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1Division of Epidemic Intelligence Service, Korea Centers for Disease Control and Prevention, Cheongju, Korea
2Department of Cancer Control and Policy, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang, Korea
3Graduate School of Public Health and Institute of Health and Environment, Seoul National University, Seoul, Korea
4Department of Architectural Engineering, Sejong University, Seoul, Korea
5Department of HVAC & Firefighting Engineering, Gachon University College of Engineering, Seongnam, Korea
6Department of Social and Preventive Medicine, Sungkyunkwan University School of Medicine, Suwon, Korea
7Division of Malaria and Parasitic Diseases, Korea Centers for Disease Control and Prevention, Cheongju, Korea
8Department of Preventive Medicine, Hanyang University College of Medicine, Seoul, Korea
©2015, Korean Society of Epidemiology
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Total | Patients |
Caregivers |
Medical staff |
|||||||
---|---|---|---|---|---|---|---|---|---|---|
Total | Eighth floor (May 15-21) | Seventh floor (May 20-29) | Seventh floor (May 15-19) | Total | Nurses on eighth floor | Nurses on seventh floor | Other | |||
Subjects (n) | 929 | 263 | 70 | 148 | 45 | 389 | 277 | 16 | 20 | 241 |
Confirmed cases (n) | 36 | 20 | 13 | 7 | 0 | 13 | 3 | 2 | 1 | 0 |
Attack rate (%) | 3.9 | 7.6 | 18.6 | 4.7 | 0.0 | 3.3 | 1.1 | 12.5 | 5.0 | 0 |
n | % | Deaths (n) | Case fatality rate (%) | p-value |
||
---|---|---|---|---|---|---|
Sex | Male | 20 | 55.6 | 3 | 15.0 | 0.76 |
Female | 16 | 44.4 | 3 | 18.8 | ||
Age (yr) | 20-29 | 4 | 11.1 | 0 | 0.0 | 0.01 |
30-39 | 2 | 5.6 | 0 | 0.0 | ||
40-49 | 11 | 30.6 | 0 | 0.0 | ||
50-59 | 11 | 30.6 | 3 | 27.3 | ||
60-69 | 2 | 5.6 | 0 | 0.0 | ||
70-79 | 6 | 16.7 | 3 | 50.0 | ||
Case type | Patient | 20 | 55.6 | 5 | 25.0 | 0.23 |
Caregivers | 13 | 36.1 | 1 | 7.7 | ||
Medical staff | 3 | 8.3 | 0 | 0.0 | ||
Generation | First | 26 | 72.2 | 4 | 15.4 | 0.74 |
Second | 10 | 27.8 | 2 | 20.0 | ||
Underlying diseases | No | 17 | 47.2 | 0 | 0.0 | 0.003 |
Yes | 19 | 52.8 | 6 | 31.6 | ||
Diabetes mellitus | 13 | 36.1 | 4 | 30.8 | 0.09 | |
Malignancy | 9 | 25.0 | 3 | 33.3 | 0.14 | |
Respiratory diseases |
6 | 16.7 | 3 | 50.0 | 0.03 | |
Cardiac diseases |
5 | 13.9 | 3 | 60.0 | 0.01 | |
Chronic kidney disease | 3 | 8.3 | 1 | 33.3 | 0.46 | |
Clinical symptoms | Fever | 35 | 97.2 | 5 | 14.3 | 0.05 |
Cough | 20 | 55.6 | 4 | 20.0 | 0.54 | |
Sputum | 16 | 44.4 | 3 | 18.8 | 0.76 | |
Shortness of breath | 4 | 11.1 | 2 | 50.0 | 0.09 | |
Myalgia | 17 | 47.2 | 1 | 5.9 | 0.09 | |
Nausea, vomiting | 5 | 13.9 | 0 | 0.0 | 0.16 | |
Diarrhea | 7 | 19.4 | 1 | 14.3 | 0.85 | |
Disease course | Pneumonia | 13 | 36.1 | 3 | 23.1 | 0.44 |
Mechanical ventilation | 5 | 13.9 | 3 | 60.0 | 0.006 | |
ECMO | 3 | 8.3 | 3 | 100.0 | <0.001 | |
Total | 36 | 100.0 | 6 | 16.7 |
Patient zero (case #1) was admitted to the eighth floor from May 15 to May 17. Other MERS cases stayed on the eighth floor from May 15 to May 21 and on the seventh floor from May 20 to May 29. Caregivers were defined as the family members, health aides, or visitors of patients.
ECMO, extracorporeal membrane oxygenation. Log likelihood ratio test. Trend test. Respiratory diseases were defined as including chronic obstructive pulmonary disease and asthma. Cardiac diseases were defined as including ischemic heart disease, arrhythmia, and heart failure.