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Cancer screenee cohort study of the National Cancer Center in South Korea
Jeongseon Kim
Epidemiol Health. 2014;36:e2014013.   Published online August 6, 2014
DOI: https://doi.org/10.4178/epih/e2014013
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  • 33 Web of Science
  • 31 Crossref
AbstractAbstract AbstractSummary PDF
Abstract
The Cancer Screenee Cohort Study was first established in 2002 by the National Cancer Center in South Korea to investigate all possible risk factors related to cancers and to expand biological specimen banking for the development of effective methodologies for cancer detection, diagnosis, and prevention. As of July in 2014, total 41,105 participants were enrolled in this cohort. Data were collected via questionnaire, clinical examination, cancer screening, and biological specimen testing including blood, urine, and exfoliated cervical cells. The highest incidence was found to be thyroid cancer, according to a nested case-control study that was linked to the National Cancer Registry information as of December 31, 2011. Case-control, cross-sectional, and cohort studies have been published using these data since 2009. Diet and nutrition was the most published topic, followed by genetics, hepatitis B virus and liver cancer screening, methodologies, physical activity, obesity, metabolic syndrome, smoking and alcohol consumption, and blood type. Evidence from the Cancer Screenee Cohort Study is highly anticipated to reduce the burden of cancer in the Korean population and aid in the detection, diagnosis, and prevention of cancer.
Summary
Korean summary
국립암센터에서는 암을 포함한 만성질환의 포괄적인 위험요인 정보와 생물학적 시료은행을 포함하는 연구기반을 확충하기 위해 2002년 8월부터 지금까지 총 41,104건의 코호트가 구축되고 있다 (2014년 7월 31일 현재). 국립암센터 검진자 코호트 자료를 통해 암발생의 위험요인과 암의 자연사 원인을 규명하고, 역학연구 자원을 활용한 본격적인 암 분자역학 연구를 지원할 수 있을 것으로 기대한다. 뿐만 아니라, 암발생의 유전자-환경 상호작용 규명을 위한 모델을 개발하고, 개인화된 맞춤예방의학(personalized preventive medicine)의 근거지식을 제공할 수 있으며 질병예방 정책 개발 및 적용을 위한 근거를 생산함으로써 우리나라 암관리 정책 사업 평가 및 중장기 연구사업 기획을 위한 자료로 활용될 수 있다.

Citations

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