^{ 1}Research Institute, Health Insurance Review & Assessment Service, Seoul, Korea
^{ 2}Department of Preventive Medicine, Gyeongsang National University School of Medicine, Jinju, Korea
^{ 3}Department of Cancer Control and Policy, Graduated School of Cancer Science and Policy, National Cancer Center, Goyang, Korea
^{ 4}Department of Preventive Medicine, Eulji University School of Medicine, Daejeon, Korea
^{ 5}International Vaccine Institute, Seoul, Korea
^{ 6}Department of Preventive Medicine, Hanyang University College of Medicine, Seoul, Korea
^{ 7}Regional Cardiocerebrovascular Center, Chungnam National University Hospital, Daejeon, Korea
©2014, Korean Society of Epidemiology
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We first classified hepatitis A infections into eight clinical pathways and calculated the incidence rate of each clinical pathway by age group. We multiplied this incidence rate by the number of hepatitis A incidences by age group to compute the total number of incidences for each age group and clinical pathway.
Then, we segmented the total cost of a single hepatitis A case into direct and indirect costs and computed the cost of a single case for the respective age group and clinical pathway.
We multiplied the number of incidences in the respective age group and clinical pathway (outcome of step 1) with the cost of hepatitis A per person (outcome of step 2) to determine the total social cost of hepatitis A.
^{} Unit: 1,000 US dollar.
^{} Sensitivity analysis 1; 50% of base value on fatality of hepatitis A infection.
^{} Sensitivity analysis 2; 150% of base value on fatality of hepatitis A infection.
^{} Sensitivity analysis 3; 50% of base value on transplantation probability in fulminant hepatitis A infection.
^{} Sensitivity analysis 4; 150% of base value on transplantation probability in fulminant hepatitis A infection.
^{} Sensitivity analysis 5; sensitivity analysis 1 + sensitivity analysis 3.
^{} Sensitivity analysis 6; sensitivity analysis 2 + sensitivity analysis 4.