Skip Navigation
Skip to contents

Epidemiol Health : Epidemiology and Health

OPEN ACCESS
SEARCH
Search
Advanced Search
mobile menu button

Search

Page Path
HOME > Search
8 "Alcohol drinking"
Filter
Filter
Article category
Keywords
More +
Publication year
More +
Authors
More +
Funded articles
More +
Original Articles
Normal liver enzymes do not indicate safety from alcohol-related liver disease: evidence from a Korean nationwide cohort
Yeon Woo Oh, Jun Young Park, Eun-Cheol Park
Epidemiol Health. 2026;48:e2026004.   Published online January 22, 2026
DOI: https://doi.org/10.4178/epih.e2026004
  • 1,384 View
  • 51 Download
AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
OBJECTIVES
This study examined whether individuals with consistently normal liver enzyme levels are protected from alcohol-related liver disease and investigated whether heavy drinking increases liver disease risk independent of normal biomarker status.
METHODS
We conducted a nationwide cohort study using Korean National Health Insurance Service data (2002–2019), including 19,035 participants aged ≥40 years who maintained normal liver enzyme levels (aspartate aminotransferase ≤40 μ/L, alanine aminotransferase ≤40 μ/L, gamma-glutamyl transferase ≤63 μ/L for men and ≤35 μ/L for women) across multiple examinations conducted between 2002 and 2008. Participants were categorized as abstainers (≤1 time/mo), moderate drinkers (≤2 times/wk), and heavy drinkers (≥3 times/wk). Primary outcomes included incident liver disease identified using diagnostic codes. Cox proportional hazards models were used to estimate hazard ratios (HRs), with age-stratified analyses performed.
RESULTS
Heavy drinkers demonstrated a significantly higher risk of liver disease than abstainers (HR, 1.73; 95% confidence interval [CI], 1.40 to 2.14), whereas moderate drinkers showed no significant association (HR, 1.06; 95% CI, 0.94 to 1.19). Consistent patterns emerged for middle-aged adults (40–69 years), with attenuated effects among participants aged ≥70 years. When alcoholic liver disease was analyzed specifically, both moderate (HR, 1.29; 95% CI, 1.05 to 1.58) and heavy drinkers (HR, 2.86; 95% CI, 2.09 to 3.91) exhibited significantly increased hazards.
CONCLUSIONS
Despite normal liver enzyme levels, heavy alcohol consumption was associated with a significantly increased risk of liver disease. These findings challenge current reactive screening paradigms relying solely on biomarker abnormalities and support proactive alcohol counseling regardless of enzyme results. More sensitive strategies are needed for early detection of alcohol-related liver injury.
Summary
Korean summary
간 효소 수치가 지속적으로 정상 범위를 유지한 사람들에게서도 과음은 간 질환 발생 위험을 유의하게 높이는 것으로 나타났다. 이는 정상 간 효소 수치가 간 건강을 보장하지 않음을 의미하며, 간 효소 수치와 무관하게 과음자 모두를 대상으로 한 적극적인 음주 상담과 예방적 개입이 필요하다.
Key Message
Even among individuals who consistently maintain normal liver enzyme levels, heavy alcohol consumption significantly increases the risk of liver disease. These findings challenge the conventional assumption that normal biomarker results reflect hepatic safety. Proactive alcohol counseling should be provided to all heavy drinkers regardless of their liver enzyme status.
Preventable cancer cases and deaths attributable to alcohol consumption in Korea from 2015 to 2030
Soseul Sung, Jihye An, Jeehi Jung, Hyeon Sook Lee, Sungji Moon, Inah Kim, Jung Eun Lee, Aesun Shin, Sun Ha Jee, Sun-Seog Kweon, Min-Ho Shin, Sangmin Park, Seungho Ryu, Sun Young Yang, Seung Ho Choi, Jeongseon Kim, Sang-Wook Yi, Yoon-Jung Choi, Youjin Hong, Sangjun Lee, Woojin Lim, Kyungsik Kim, Sohee Park, Jeong-Soo Im, Hong Gwan Seo, Kwang-Pil Ko, Sue K. Park
Epidemiol Health. 2025;47:e2025009.   Published online February 27, 2025
DOI: https://doi.org/10.4178/epih.e2025009
  • 6,241 View
  • 167 Download
AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
OBJECTIVES
Alcohol consumption is causally linked to several cancers, and major health organizations classify it as a carcinogen. This study assessed the impact of alcohol consumption on cancer incidence and mortality in Korea in 2015 and 2020, projected trends up to 2030, and compared results based on different criteria.
METHODS
The relative risk of cancer associated with alcohol consumption in Korea was determined through a meta-analysis of alcohol-related relative risks for specific cancers, using primary data from the Korean Cohort Study within the Korean Cohort Consortium. The population-attributable fraction (PAF) was calculated using Levin’s formula, incorporating drinking prevalence and the number of cancer cases and deaths, with a 15-year latency period assumed.
RESULTS
In Korea, the PAF for alcohol consumption, based on ever/never drinking criteria, was higher than that calculated using other criteria, except for the PAF based on past and current/never drinking criteria. Alcohol consumption contributed to 3.58% of all cancer cases and 3.28% of cancer deaths in 2015. It accounted for 4.58% of new cancer cases in male and 2.08% in female, with a higher contribution to incidence than mortality (4.00 and 2.25% of cancer deaths in male and female, respectively). Projections indicate that alcohol-related cancer PAF will decrease by 17.2% in male but increase by 70.2% in female by 2030.
CONCLUSIONS
This study highlights the impact of alcohol consumption on cancer in Korea, emphasizing the need for sex-specific regulations to address sex differences.
Summary
Korean summary
2015년 알콜 섭취는 한국에서 전체 암 발생의 3.58%, 암 사망의 3.28%를 차지했으며, 남성(4.58%)이 여성(2.08%)보다 더 큰 영향을 받았음. 2030년까지 남성의 알콜 관련 암 발생률은 감소할 것으로 예상되지만, 여성에서는 급증할 것으로 보임. 이러한 결과는 특히 여성에서 증가하는 추세를 반영하여 성별 맞춤형 공공 보건 정책의 필요성을 시사함.
Key Message
In 2015, alcohol consumption was responsible for 3.58% of all cancer cases and 3.28% of cancer deaths in Korea, with a more significant impact on males (4.58% of new cases) than females (2.08%). Projections indicate a decrease in alcohol-related cancer cases among males but a sharp increase in females by 2030. These findings highlight the need for sex-specific public health measures to address the growing impact of alcohol on cancer, particularly the increasing trend in female cases.
Special Articles
Cancer risk based on alcohol consumption levels: a comprehensive systematic review and meta-analysis
Seunghee Jun, Hyunjin Park, Ui-Jeong Kim, Eun Jeong Choi, Hye Ah Lee, Bomi Park, Soon Young Lee, Sun Ha Jee, Hyesook Park
Epidemiol Health. 2023;45:e2023092.   Published online October 16, 2023
DOI: https://doi.org/10.4178/epih.e2023092
  • 65,535 View
  • 1,158 Download
  • 44 Web of Science
  • 57 Crossref
AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
OBJECTIVES
Alcohol consumption is a well-established risk factor for cancer. Despite extensive research into the relationship between alcohol consumption and cancer risk, the effect of light alcohol consumption on cancer risk remains a topic of debate. To contribute to this discourse, we conducted a comprehensive systematic review and meta-analysis.
METHODS
Our systematic review aimed to investigate the associations between different levels of alcohol consumption and the risk of several cancer types. We focused on analyzing prospective associations using data from 139 cohort studies. Among them, 106 studies were included in the meta-analysis after a quantitative synthesis.
RESULTS
Our analysis did not find a significant association between light alcohol consumption and all-cause cancer risk (relative risk, 1.02; 95% confidence interval, 0.99 to 1.04), but we observed a dose-response relationship. Light alcohol consumption was significantly associated with higher risks of esophageal, colorectal, and breast cancers. Light to moderate drinking was associated with elevated risks of esophageal, colorectal, laryngeal, and breast cancers. Heavy drinking was also found to contribute to the risk of stomach, liver, pancreas, and prostate cancers, thereby increasing the risk of almost all types of cancer. Additionally, females generally had lower cancer risks compared to males.
CONCLUSIONS
Our findings highlight that cancer risks extend beyond heavy alcohol consumption to include light alcohol consumption as well. These findings suggest that there is no safe level of alcohol consumption associated with cancer risk. Our results underscore the importance of public health interventions addressing alcohol consumption to mitigate cancer risks.
Summary
Korean summary
본 연구는 코호트 연구를 기반으로 하여 음주의 수준에 따른 암 위험 연관성에 대해 체계적 문헌고찰(139편)과 메타분석(106편)을 수행하였다. 연구 결과, 음주와 암 위험 사이에 용량-반응 관계가 나타났으며, 소량의 음주는 암 유형에 따라 차이가 있었으나, 식도암, 대장암, 전립선암(남성), 유방암(여성)에서 암 위험과의 연관성이 있음을 발견했다. 따라서, 암 위험 측면에서 음주에 안전한 수준이 없음을 시사하며, 음주와 관련된 잠재적 피해를 완화하기 위해서는 음주 지침 강화와 같은 공중보건개입이 필요하다.
Key Message
The aim of this study was to assess the relationship between different levels of alcohol consumption and the risk of various cancer types through a systematic review and meta-analysis, providing insights into the ongoing debate about alcohol consumption and cancer causality. The findings support a dose-response relationship between alcohol consumption levels and cancer risk and the light alcohol consumption was associated with risks of esophageal, colorectal, prostate (male), and breast (female) cancer. These results emphasize the absence of a safe threshold for alcohol consumption in terms of cancer risk.

Citations

Citations to this article as recorded by  
  • Prévention et dépistage des cancers dans les rhumatismes inflammatoires chroniques
    Elodie Mamou, Laetitia Morardet, Djaha Mogni, Bruno Fautrel, Laure Gossec
    Revue du Rhumatisme.2026; 93(1): 61.     CrossRef
  • MetALD Was an Independent Risk Factor for the Recurrence of Early Esophageal Squamous Cell Carcinoma After Endoscopic Resection: A Multicenter Cohort Study Using Directed Acyclic Graphs
    Michita Mukasa, Shuhei Fukunaga, Tomoyuki Nakane, Tomonori Cho, Shinpei Minami, Hiroshi Tanaka, Daiki Ohzono, Tomokazu Yoshio, Yusei Watanabe, Dan Nakano, Tsubasa Tsutsumi, Toshihiro Araki, Taku Morita, Takuji Torimura, Ryuichi Nouno, Keigo Emori, Hidetos
    Hepatology Research.2026; 56(4): 467.     CrossRef
  • Incidence and Mortality Risks of Gastrointestinal Cancers During Working‐Age Period: Trends and Disparities in 204 Countries and Territories (1990–2021)
    Yiming Song, Zhongge Ji, Xunbing Zhang, Qian Liang, Zeyu Li, Xiaojie Huang, Jinnan Chen, Yujie Zhou, Xinyuan Wang, Zhao Li, Liuyi Yang, Yixin Qian, Xiaolu Lin, Qingwei Zhang, Xiaobo Li
    Med Research.2026; 2(1): 58.     CrossRef
  • Green tea catechins and prostate cancer: mechanisms, clinical evidence, and safety: a narrative review
    Hatice Berin Altinoz, Nevin Sanlier
    BMC Cancer.2026;[Epub]     CrossRef
  • European Code Against Cancer, 5th edition – tobacco and nicotine containing products, second‐hand smoke, alcohol and cancer
    Ariadna Feliu, Annie S. Anderson, Linda Bauld, Esteve Fernández, Michael Leitzmann, Sherry Morris, Bernard Srour, Constantine Vardavas, Ioana Vlad, Sabine Vuik, Matty Weijenberg, Rosa Alvarado‐Villacorta, Carlos Canelo‐Aybar, Hajo Zeeb, Joachim Schüz, Eri
    Molecular Oncology.2026; 20(1): 6.     CrossRef
  • Alcohol Consumption and Health Outcomes Among Men in a Rural HIV-Endemic Cohort in South Africa
    Alison C. Castle, Sheela V. Shenoi, Kobus Herbst, Emily B. Wong, Thumbi Ndung'u, Willem Hanekom, Judith A. Hahn, Mark J. Siedner
    Wellcome Open Research.2026; 10: 469.     CrossRef
  • Menopausal hormone treatment and breast cancer
    Anne Gompel, Richard Simcock
    The Lancet Diabetes & Endocrinology.2026; 14(3): 259.     CrossRef
  • Dynamics of mortality from causes directly attributable to alcohol and their contribution to all-cause mortality in the Russian Federation
    Esedulla M. Osmanov, Vladimir A. Reshetnikov, Temirlan M. Akaev, Biysultan S. Khamzaev, Magomedsaid A. Omarov
    Terapevticheskii arkhiv.2026; 97(12): 981.     CrossRef
  • Relative handgrip strength, lifestyles and cancer risk in older adults: a multi-country cohort study
    Yanxue Lian, Pincheng Luo
    QJM: An International Journal of Medicine.2026;[Epub]     CrossRef
  • Aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) for preventing colorectal cancer and colorectal adenoma in the general population
    Zhaolun Cai, Yang Meng, Wenming Yang, Yihui Han, Dan Cao, Bo Zhang
    Cochrane Database of Systematic Reviews.2026;[Epub]     CrossRef
  • Screening older adults for alcohol use in orthopaedic care: Healthcare team perspectives, current practices, and barriers
    Ashley C. Helle, Bryce Rizvanović, Kylee Rucinski, Samantha M. Portis
    Journal of Orthopaedic Reports.2026; : 100954.     CrossRef
  • Judith and Holofernes: alcohol's role in male sexual health in the light of the systems sexology
    Dimitri Yannas, Andrea Sansone, Angelo Cignarelli, Daniele Santi, Giorgia Spaggiari, Francesco Giorgino, Tommaso B Jannini, Alberto Siracusano, Emmanuele A Jannini
    Sexual Medicine Reviews.2026;[Epub]     CrossRef
  • Obesity, Bariatric Surgery, and Cancer Risk: Nutritional Perspectives and Long-Term Clinical Implications
    Claudia Reytor-González, Gerardo Sarno, Martha Montalvan, Ludovica Verde, Giuseppe Annunziata, Luigi Barrea, Giovanna Muscogiuri, Daniel Simancas-Racines
    Nutrients.2026; 18(4): 685.     CrossRef
  • Ultra-processed food consumption and risk of oesophagus, stomach, and pancreatic cancers: a multi case–control study
    Laura Torres-Collado, Sandra González-Palacios, Laura María Compañ-Gabucio, Carolina Ojeda-Belokon, Marielisa Gabriela Belisario-Ubeto, Manuela García-de-la-Hera, Alejandro Oncina-Cánovas, Jesús Vioque
    Frontiers in Nutrition.2026;[Epub]     CrossRef
  • Alcohol‐cancer risk communication on social media: A content analysis of alcohol‐related Instagram and TikTok posts
    Joseph Alejandro, Christina Mair, Robert W. S. Coulter, Kar‐Hai Chu, Alexa Pierce, Kennedy Sawicki, Arpita Tripathi, Jaime E. Sidani
    Alcohol, Clinical and Experimental Research.2026;[Epub]     CrossRef
  • Gastric Cancer in China, 1990 to 2023
    Shuai Wang, Jingbo Lv, Li Wang, Xiaoming Lin, Hao Wu, Xueyuan Cao
    Journal of Clinical Gastroenterology.2026;[Epub]     CrossRef
  • Alcohol use: less is better. An umbrella systematic review of clinical interventions, policies, and dose–response health risks in adults
    Tommaso Dionisi, Vittorio De Vita, Giovanna Di Sario, Antonio Gasbarrini, Giovanni Addolorato
    European Journal of Internal Medicine.2026; : 106837.     CrossRef
  • Dietary Factors Associated With the Progression of Gastric Intestinal Metaplasia: A Multicenter, Prospective Cohort Study in a Western Population
    N.E.A. Kapteijn, F.E. Marijnissen, J.K.F. Pluimers, I.L. Holster, L.G. Capelle, I. Schot, M.P. Anten, E.M. Witteman, F. ter Borg, J.P.W. Burger, M. Doukas, E.J. Kuipers, J. Honing, M.C.W. Spaander
    Clinical and Translational Gastroenterology.2026;[Epub]     CrossRef
  • Aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) for preventing colorectal cancer and colorectal adenoma in the general population
    Zhaolun Cai, Yang Meng, Wenming Yang, Yihui Han, Dan Cao, Bo Zhang
    Cochrane Database of Systematic Reviews.2026;[Epub]     CrossRef
  • Content analysis of output from generative artificial intelligence chatbots when prompted about breast cancer and alcohol consumption
    A.B. Anbari, K. Maturino, O. Goth, G.H. Jesudasan, J.R. Bautista
    Public Health.2026; 255: 106278.     CrossRef
  • Unraveling the bidirectional link between cancer and dementia and the impact of cancer therapies on dementia risk: A systematic review and meta‐analysis
    Liwei Ma, Edwin C. K. Tan, Benjamin Goudey, Liang Jin, Yijun Pan
    Alzheimer's & Dementia.2025;[Epub]     CrossRef
  • Associations of lifestyle factors with oral cancer risk: An umbrella review
    Haobo Xu, Zhonglan Gao, Hairong Liu, Liya An, Ting Yang, Bojun Zhang, Guobin LIU, Dali Sun
    Journal of Stomatology Oral and Maxillofacial Surgery.2025; 126(3): 102234.     CrossRef
  • Estudio bibliométrico de las publicaciones sobre cirugía pancreática realizadas por cirujanos españoles
    Juan Jesús Rubio-García, Celia Villodre Tudela, Cándido Alcázar López, Silvia Carbonell Morote, Mariano Franco Campello, Paola Melgar Requena, Adrián Paredes Segura, José Manuel Ramia Ángel
    Cirugía Española.2025; 103(4): 201.     CrossRef
  • Personalized Lifestyle Interventions for Prevention and Treatment of Obesity-Related Cancers: A Call to Action
    Mohamad Motevalli, Fatima Cody Stanford
    Cancers.2025; 17(8): 1255.     CrossRef
  • Bibliometric study of publications on pancreatic surgery carried out by spanish surgeons
    Juan Jesús Rubio-García, Celia Villodre Tudela, Cándido Alcázar López, Silvia Carbonell Morote, Mariano Franco Campello, Paola Melgar Requena, Adrián Paredes Segura, José Manuel Ramia Ángel
    Cirugía Española (English Edition).2025; 103(4): 201.     CrossRef
  • Alcohol consumption and breast lesions: targets for risk-based screening in high-risk Italian women
    Sonia Cerrai, Alessio Lachi, Michela Franchini, Stefania Pieroni, Giada Anastasi, Marco Scalese, Anna Odone, Silvano Gallus, Luc Smits, Sabrina Molinaro
    Breast Cancer.2025; 32(5): 970.     CrossRef
  • Design and Optimization of Surface Plasmon Resonance-Based Non-Invasive Refractive Index Biosensor Using Ag-SiO2 Materials for Alcoholic Beverages Compound Detection
    Trupti Kamani, Shobhit K. Patel, Sana Ben Khalifa, Pankaj Pathak, Saleh Chebaane, Marouan Kouki
    Plasmonics.2025; 20(10): 9017.     CrossRef
  • Invisible foes: how air pollution and lifestyle conspire in the rise of colorectal cancer
    Di Zhao, Meng Zhu
    QJM: An International Journal of Medicine.2025; 118(7): 501.     CrossRef
  • Wine Consumption and Lung Cancer Risk: A Systematic Review and Meta-Analysis
    Carlotta Bertola, Camilla Gobbetti, Gaia Baccarini, Roberto Fabiani
    Nutrients.2025; 17(8): 1322.     CrossRef
  • A narrative review on alcohol and alimentary tract cancer with special emphasis on acetaldehyde and oxidative stress
    Helmut Karl Seitz
    Zeitschrift für Gastroenterologie.2025; 63(09): 960.     CrossRef
  • Association of Cigarette Smoking and Alcohol Drinking With Risk of 12 Common Cancers Among Low-Income American Adults in the Southeastern United States
    Jiajun Shi, Wanqing Wen, Qiuyin Cai, Martha J. Shrubsole, Xiao-Ou Shu, Wei Zheng
    Cancer Control.2025;[Epub]     CrossRef
  • Identification of MMP14 and MKLN1 as colorectal cancer susceptibility genes and drug-repositioning candidates from a genome-wide association study
    Dabin Yun, Jung-Ho Yang, Jin-ah Sim, Minjung Kim, Ji Won Park, Seung Yong Jeong, Aesun Shin, Sun-Seog Kweon, Nan Song
    Journal of Translational Medicine.2025;[Epub]     CrossRef
  • Research Progress on Risk Factors and Endoscopic Diagnosis of Gastric Mucosal Intestinal Metaplasia
    思妤 刘
    Advances in Clinical Medicine.2025; 15(05): 1135.     CrossRef
  • Global Cancer Burden Forecast for 204 Countries and Territories, 2022–2050: A Predictive Analysis from the Global Burden of Disease Study 2021
    Jinghao Liang, Yijian Lin, Wenxi Wang, Jingchun Ni, Hongmiao Lin, Zishan Huang, Jihao Qi, Zhaofeng Tan, Hengrui Liang, Jianxing He
    Cancer Letters.2025; 629: 217883.     CrossRef
  • Global burden of breast cancer attributable to alcohol consumption: a multi-regional observational analysis (1990–2021)
    Fangfang Cui, Yuntian Chu, Weiyi Wang, Meihao Ji, Sidong Zhang, Zhengyu Wu, Yadong Song
    Addictive Behaviors.2025; 170: 108426.     CrossRef
  • Patterns of cigarette, e-cigarette, heated tobacco, and alcohol use in solid organ transplant recipients, a pre- versus posttransplant comparison: Survey results from a transplantation center in Poland
    Zuzanna Marczak, Bartosz Olkowski, Olga Maria Rostkowska, Dorota Miszewska-Szyszkowska, Olga Kozińska-Przybył, Tomasz Warężak, Magdalena Durlik
    Tobacco Prevention & Cessation.2025; 11(June): 1.     CrossRef
  • Analysis of Novel DNA Adducts Derived from Acetaldehyde
    Yuuki Betsuyaku, Mina Motohashi, Akira Sassa, Takeji Takamura-Enya, Yukari Totsuka
    Biomolecules.2025; 15(6): 878.     CrossRef
  • Granulocyte function in response to acute alcohol consumption: temporal shifts from proinflammatory activation to antiinflammatory modulation in healthy volunteers
    Ramona Sturm, Florian Haag, Helen Rinderknecht, Jasmin Maria Bülow, Nils Wagner, Julian Zabel, Christian B Bergmann, Ingo Marzi, Borna Relja
    Journal of Leukocyte Biology.2025;[Epub]     CrossRef
  • Soy and Isoflavones: Revisiting Their Potential Links to Breast Cancer Risk
    Catherine Bennetau-Pelissero
    Nutrients.2025; 17(16): 2621.     CrossRef
  • Alcohol Consumption and Health Outcomes Among Men in a Rural HIV-Endemic Cohort in South Africa
    Alison C. Castle, Sheela V. Shenoi, Kobus Herbst, Emily B. Wong, Thumbi Ndung'u, Willem Hanekom, Judith A. Hahn, Mark J. Siedner
    Wellcome Open Research.2025; 10: 469.     CrossRef
  • RE: Drinking pattern and time lag of alcohol consumption with colorectal cancer risk in US men and women
    Gokhan Koker, Gulhan Ozcelik
    JNCI: Journal of the National Cancer Institute.2025; 117(11): 2409.     CrossRef
  • Light to Moderate Alcohol Consumption and Cancer Incidence: The Norwegian Women and Health Cohort Study
    Fjorida Llaha, Idlir Licaj, Ekaterina Sharashova, Pietro Ferrari, Marko Lukic, Kristin Benjaminsen Borch
    Clinical Epidemiology.2025; Volume 17: 807.     CrossRef
  • Association between alcohol consumption and the risk of developing breast cancer: a systematic review
    Siane Silva Cesar, Gabriel Nuñez Costa, Marilia Niedermayer Fagundes, Mary Gomes Silva
    Mastology.2025;[Epub]     CrossRef
  • Direct and Indirect Costs of Cancer in Adult Population of Poland in the Period 2021–2023
    Izabela Gąska, Aleksandra Czerw, Monika Pajewska, Olga Partyka, Dorota Charkiewicz, Andrzej Deptała, Anna Badowska-Kozakiewicz, Katarzyna Sygit, Ireneusz Dziubek, Paulina Wojtyła-Buciora, Jarosław Drobnik, Piotr Pobrotyn, Dorota Waśko-Czopnik, Tomasz Sowi
    Cancers.2025; 17(23): 3725.     CrossRef
  • Methionine Adenosyltransferase 1A and S-Adenosylmethionine in Alcohol-Associated Liver Disease
    Lucía Barbier-Torres, Jyoti Chhimwal, José M. Mato, Shelly C. Lu
    Antioxidants.2025; 14(12): 1486.     CrossRef
  • The Need for a Systems Biology Approach in Cancer Explained
    Hehuan Zhu, Xi Zhang, Ehsan Nazemalhosseini-Mojarad, Jessica Roelands, Lysanne D. A. N. de Muynck, Cor J. Ravensbergen, Rachel Hoorntje, Imke Stouten, Marianne Hokland, Alexander L. Vahrmeijer, Rob A. E. M. Tollenaar, Edwin Koster, Peter J. K. Kuppen
    International Journal of Molecular Sciences.2025; 27(1): 141.     CrossRef
  • Unmasking the ‘rods and rings’ antinuclear antibody pattern: a sign of hepatitis C treatment and a risk factor for cerebrovascular disease
    Ko-Ming Lin, Kuang-Hui Yu, Chao-Yang Hsiao, Yu-Jih Su, Tien-Ming Chan
    Annals of Medicine.2025;[Epub]     CrossRef
  • Exploring genetic associations of Crohn’s disease and ulcerative colitis with extraintestinal cancers in European and East Asian populations
    Chengdong Yu, Jiawei Xu, Siyi Xu, Lei Tang, Qinyuan Han, Xiaoqiang Zeng, Yanxiao Huang, Tenghua Yu, Zhengkui Sun
    Frontiers in Immunology.2024;[Epub]     CrossRef
  • The Impact of Tobacco Smoking and Alcohol Consumption on the Development of Gastric Cancers
    Waku Hatta, Tomoyuki Koike, Naoki Asano, Yutaka Hatayama, Yohei Ogata, Masahiro Saito, Xiaoyi Jin, Kaname Uno, Akira Imatani, Atsushi Masamune
    International Journal of Molecular Sciences.2024; 25(14): 7854.     CrossRef
  • Genetic Heterogeneity Across Dimensions of Alcohol Use Behaviors
    Jeanne E. Savage, Peter B. Barr, Tanya Phung, Younga H. Lee, Yingzhe Zhang, Vivia V. McCutcheon, Tian Ge, Jordan W. Smoller, Lea K. Davis, Jacquelyn Meyers, Bernice Porjesz, Danielle Posthuma, Travis T. Mallard, Sandra Sanchez-Roige
    American Journal of Psychiatry.2024; 181(11): 1006.     CrossRef
  • To Drink or Not to Drink? Investigating Alcohol’s Impact on Prostate Cancer Risk
    Aris Kaltsas, Michael Chrisofos, Evangelos N. Symeonidis, Athanasios Zachariou, Marios Stavropoulos, Zisis Kratiras, Ilias Giannakodimos, Asterios Symeonidis, Fotios Dimitriadis, Nikolaos Sofikitis
    Cancers.2024; 16(20): 3453.     CrossRef
  • Factors associated with acquiring exercise habits through health guidance for metabolic syndrome among middle-aged Japanese workers: A machine learning approach
    Jiawei Wan, Kyohsuke Wakaba, Takeshi Onoue, Kazuyo Tsushita, Yoshio Nakata
    Preventive Medicine Reports.2024; 48: 102915.     CrossRef
  • Development of an algorithm for identifying paraneoplastic ischemic stroke in association with lung, pancreatic, and colorectal cancer
    Rebecca Kassubek, Marc-Andre G. R. Winter, Jens Dreyhaupt, Mona Laible, Jan Kassubek, Albert C. Ludolph, Jan Lewerenz
    Therapeutic Advances in Neurological Disorders.2024;[Epub]     CrossRef
  • Alimentación y cáncer
    Carlos A. González Svatetz
    FMC - Formación Médica Continuada en Atención Primaria.2024; 31(8): 403.     CrossRef
  • Alcohol consumption and its association with cancer, cardiovascular, liver and brain diseases: a systematic review of Mendelian randomization studies
    Naouras Bouajila, Cloé Domenighetti, Henri-Jean Aubin, Mickael Naassila
    Frontiers in Epidemiology.2024;[Epub]     CrossRef
  • Global, regional, and national trends in gastric cancer burden: 1990-2021 and projections to 2040
    Tao Zhang, Yiqun Zhang, Xiaofei Leng
    Frontiers in Oncology.2024;[Epub]     CrossRef
  • Alcohol Consumption and Breast and Ovarian Cancer Development: Molecular Pathways and Mechanisms
    Francesca Fanfarillo, Brunella Caronti, Marco Lucarelli, Silvia Francati, Luigi Tarani, Mauro Ceccanti, Maria Grazia Piccioni, Loredana Verdone, Micaela Caserta, Sabrina Venditti, Giampiero Ferraguti, Marco Fiore
    Current Issues in Molecular Biology.2024; 46(12): 14438.     CrossRef
Genetically determined alcohol consumption and cancer risk in Korea
Keum Ji Jung, Ji Woo Baek, Sang Yop Shin, Sun Ha Jee
Epidemiol Health. 2023;45:e2023077.   Published online August 23, 2023
DOI: https://doi.org/10.4178/epih.e2023077
  • 18,744 View
  • 190 Download
  • 3 Web of Science
  • 3 Crossref
AbstractAbstract AbstractSummary PDF
Abstract
OBJECTIVES
The purpose of this study was to determine the causal relationship between the genetically determined amount of alcohol consumption and the occurrence of major cancers.
METHODS
The data used in this study were from 129,324 people selected from the Korean Cancer Prevention Study-II, the participants of which visited 18 health examination centers between 2004 and 2013. Cancer incidence was confirmed as of 2020 using data from the National Cancer Center. A genome-wide association study (GWAS) on alcohol consumption was performed using PLINK 2.0, and sex, age, chip type, and principal components were adjusted.
RESULTS
From the GWAS, a genetic risk score for alcohol consumption was calculated and genetically determined alcohol consumption (GDAC) was estimated. GDAC was divided into quintile groups and showed significant causal relationships with rectal cancer and liver cancer, but not with other cancers. For liver cancer, an association was shown in the hepatitis B surface antigen (HBsAg)-negative group, and a particularly strong association was found in the over-60-year-old HBsAg-negative group, in which, compared to the GDAC Q1 group, the Q4 group had a 2.35 times higher risk (95% confidence interval [CI], 1.05 to 5.23), and the Q5 group had a 2.40 times higher risk (95% CI, 1.09 to 5.30).
CONCLUSIONS
The results of this study provided evidence that the amount of alcohol consumed is causally related to the occurrence of rectal cancer and liver cancer in HBsAg-negative individuals. Additional studies should be continued for other cancer types through long-term follow-up.
Summary
Korean summary
본 연구는 유전적으로 결정되는 음주량과 주요 암 발생 사이의 인과 관계를 밝히고자 하였다. 그 결과 유전적으로 결정되는 음주량이 증가할수록 직장암 발생 위험이 높아졌고, 특히 HBsAg 음성인 사람에서 간암 발생 위험이 높아지는 것으로 밝혀졌다.
Key Message
The purpose of this study was to reveal the causal relationship between genetically determined alcohol consumption and the incidence of major cancers. As a result, it was found that as the genetically determined amount of alcohol consumed increases, the risk of rectal cancer increases, and especially in people who are HBsAg negative, the risk of liver cancer increases.

Citations

Citations to this article as recorded by  
  • Cohort profile update: the Korean Cancer Prevention Study-II (KCPS-II) biobank
    Heejin Kimm, Keum Ji Jung, Wes Spiller, Yeun Soo Yang, So Young Kim, Min Young Park, Sun Mi Lee, Sun Ha Jee
    Epidemiology and Health.2025; 47: e2025040.     CrossRef
  • A pan-cancer analysis of the prognostic implication and oncogenic role of tubulin epsilon and delta complex 2 (TEDC2) in human tumors
    Yang Liu, Jie Zhu, Jing Shen, Yuting Lu, Ke Pan, Chuan Tong, Yao Wang
    Frontiers in Immunology.2024;[Epub]     CrossRef
  • Cancer risk based on alcohol consumption levels: a comprehensive systematic review and meta-analysis
    Seunghee Jun, Hyunjin Park, Ui-Jeong Kim, Eun Jeong Choi, Hye Ah Lee, Bomi Park, Soon Young Lee, Sun Ha Jee, Hyesook Park
    Epidemiology and Health.2023; 45: e2023092.     CrossRef
Original Articles
Trends in health behaviors over 20 years: findings from the 1998-2018 Korea National Health and Nutrition Examination Survey
Soyeon Kim, Sunhye Choi, Jihee Kim, Suyeon Park, Young-Taek Kim, Ok Park, Kyungwon Oh
Epidemiol Health. 2021;43:e2021026.   Published online April 19, 2021
DOI: https://doi.org/10.4178/epih.e2021026
  • 28,861 View
  • 385 Download
  • 42 Web of Science
  • 34 Crossref
AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
OBJECTIVES
This study aimed to examine the trends in health behaviors in Korean population using data from the Korea National Health and Nutrition Examination Survey (KNHANES).
METHODS
The subjects were 96,408 adults aged 19 years or older who participated in the first (1998) through seventh (2016-2018) KNHANES health interview. The prevalence of health behaviors (cigarette smoking, alcohol drinking, and physical activity) and annual percent change (APC) were estimated using SAS and the Joinpoint program.
RESULTS
The prevalence of current cigarette smoking in men decreased by 2.8%p (APC= -2.8, p< 0.001) annually over the 20-year period, and the prevalence of exposure to secondhand smoke at home substantially decreased compared to 2005 (APC= -8.8, p< 0.001). Compared to 2005, the prevalence of current alcohol drinking in women, but not men, increased (APC= 2.0, p< 0.001), and the prevalence of binge drinking decreased in men (APC= -0.7, p< 0.001) and increased in women (APC= 2.4, p< 0.001). The prevalence of aerobic physical activity decreased from 2014 in both gendersd (p< 0.001). The prevalence of healthy behaviors practice (non-smoking, alcohol abstinence, and aerobic physical activity) was down-trending (APC= -5.3, p< 0.001), especially among women (APC= -6.4, p< 0.001).
CONCLUSIONS
Over the past 20 years, smoking behaviors improved. However, drinking behavior was unchanged and physical activity indicators markedly decreased. More active programs are necessary for improving health behaviors, which are major risk factors linked to chronic diseases.
Summary
Korean summary
국민건강영양조사(1998-2018) 자료를 활용하여 지난 20년간 성인의 건강행태를 분석한 결과 흡연율과 간접흡연 노출률은 지속적으로 감소하였고, 신체활동 실천율 또한 감소하였다. 월간음주율과 폭음률의 경우 남자는 큰 변화가 없었던 반면 여자는 모두 증가하였다.
Key Message
This study aimed to examine the trends in health behaviors in Korean population using data from the 1998-2018 Korea National Health and Nutrition Examination Survey (KNHANES). Over the past 20 years, the prevalence of cigarette smoking and exposure to secondhand smoke in Korean adults consistently decreased, as well as the prevalence of physical activity. There was no considerable change in men, whereas in women, the prevalence of alcohol drinking and binge drinking both increased.

Citations

Citations to this article as recorded by  
  • Health literacy mediates the association of education levels with engagement in leisure-time physical activity and muscle-strengthening exercise: a population-based study of Korea
    Seong-Uk Baek, Jin-Ha Yoon
    Postgraduate Medical Journal.2026; 102(1204): 140.     CrossRef
  • Plan and operations of the 10th Korea National Health and Nutrition Examination Survey (2025–2027)
    Sun-Ja Kim, Sihyun Park, Sunja Kim, Suyeon Park, Yoonjung Kim, Yunjung Choi, Sungha Yun, Kyungwon Oh
    Epidemiology and Health.2026; 48: e2026001.     CrossRef
  • Effect of healthy lifestyle score trajectory on all-cause mortality in the late middle-aged and older population: Finding from 17-year retrospective cohort study
    Jeong Min Yang, Jieun Hwang
    Experimental Gerontology.2025; 200: 112681.     CrossRef
  • Cancer risk according to lifestyle risk score trajectories: a population-based cohort study
    Thi Minh Thu Khong, Thi Tra Bui, Hee-Yeon Kang, Eunjung Park, Moran Ki, Yoon-Jung Choi, Byungmi Kim, Jin-Kyoung Oh
    BJC Reports.2025;[Epub]     CrossRef
  • Age at first drink as a predictor of all-cause mortality of middle-aged Koreans
    Horim A Hwang, Dong Jun Kim, Seongju Kim, Hooyeon Lee
    International Journal of Epidemiology.2025;[Epub]     CrossRef
  • Trends of health behaviors among cancer patients in Korea: a cross-sectional time series analysis
    Noor Afif Mahmudah, Young-Kwon Park, Minsu Ock
    BMC Cancer.2025;[Epub]     CrossRef
  • Temporal Trends in Handgrip Strength and Associated Factors among Korean Adults from 2014 to 2019: Analysis of Korea National Health and Nutrition Examination Survey Data
    Yun Ki Kim, Sukyoung Jung, Seung Hoo Lee, Jaehee Seo
    Clinics in Orthopedic Surgery.2025; 17(5): 891.     CrossRef
  • Breakfast Skipping Among Dormitory- and Home-Residing High School Students: Insights from the Korea Youth Risk Behavior Survey 2018–2024
    Jeong Mi Lee, Jee-Seon Shim
    Nutrients.2025; 17(20): 3190.     CrossRef
  • Preventable cancer cases and deaths attributable to tobacco smoking in Korea from 2015 to 2030
    Soseul Sung, Jihye An, Jeehi Jung, Hyeon Sook Lee, Sungji Moon, Inah Kim, Jung Eun Lee, Aesun Shin, Sun Ha Jee, Sun-Seog Kweon, Min-Ho Shin, Sangmin Park, Seungho Ryu, Sun Young Yang, Seung Ho Choi, Jeongseon Kim, Sang-Wook Yi, Yoon-Jung Choi, Youjin Hong
    Epidemiology and Health.2025; 47: e2025008.     CrossRef
  • Variability in the association of smoking status with the prevalence of diabetes mellitus in the Korean population according to different definitions of smoking status: analysis based on the Korea National Health and Nutrition Examination Survey (2014-202
    Yechan Kyung, Young Sook Park, Mi Hyeon Jin, Hae Jeong Lee
    International Journal of Environmental Health Research.2024; 34(9): 3218.     CrossRef
  • Relationship between Handgrip Strength and Incident Diabetes in Korean Adults According to Gender: A Population-Based Prospective Cohort Study
    Sung-Bum Lee, Min-Kyeung Jo, Ji-Eun Moon, Hui-Jeong Lee, Jong-Koo Kim
    Journal of Clinical Medicine.2024; 13(2): 627.     CrossRef
  • Influencing factors of health screening among retirees: an extended TPB approach
    Jiayi Xu, Younghwan Pan, Qiongzhen Li
    Frontiers in Public Health.2024;[Epub]     CrossRef
  • Chronic Disease Patterns and Their Relationship With Health-Related Quality of Life in South Korean Older Adults With the 2021 Korean National Health and Nutrition Examination Survey: Latent Class Analysis
    Mi-Sun Lee, Hooyeon Lee
    JMIR Public Health and Surveillance.2024; 10: e49433.     CrossRef
  • Telehealth Uptake Among Hispanic People During COVID-19: Retrospective Observational Study
    Di Shang, Cynthia Williams, Hera Culiqi
    JMIR Medical Informatics.2024; 12: e57717.     CrossRef
  • Contemporary Statistics of Acute Ischemic Stroke and Transient Ischemic Attack in 2021: Insights From the CRCS-K-NIH Registry
    Do Yeon Kim, Tai Hwan Park, Yong-Jin Cho, Jong-Moo Park, Kyungbok Lee, Minwoo Lee, Juneyoung Lee, Sang Yoon Bae, Da Young Hong, Hannah Jung, Eunvin Ko, Hyung Seok Guk, Beom Joon Kim, Jun Yup Kim, Jihoon Kang, Moon-Ku Han, Sang-Soon Park, Keun-Sik Hong, Ho
    Journal of Korean Medical Science.2024;[Epub]     CrossRef
  • Health-Related Quality of Life and Associated Comorbidities in Community-Dwelling Women with Breast Cancer
    Dong Kee Jang, Hyung Seok Nam, Jieun Kim, Yeo Hyung Kim
    Journal of Clinical Medicine.2024; 13(17): 5321.     CrossRef
  • Long-term exposure to PM2.5 and mortality: a national health insurance cohort study
    Jeongmin Moon, Ejin Kim, Hyemin Jang, Insung Song, Dohoon Kwon, Cinoo Kang, Jieun Oh, Jinah Park, Ayoung Kim, Moonjung Choi, Yaerin Cha, Ho Kim, Whanhee Lee
    International Journal of Epidemiology.2024;[Epub]     CrossRef
  • Adherence to Cancer Prevention Guidelines and Cancer Incidence and Mortality: A Population-Based Cohort Study
    Jin-Kyoung Oh, Minji Han, Byungmi Kim, Eun Young Park
    Cancer Research and Treatment.2023; 55(1): 15.     CrossRef
  • Ocular motility disorders following coronavirus disease-19 vaccination
    Kyung-Ah Park, Hyeshin Jeon, Dong Gyu Choi, Jae Ho Jung, Hyun-Jin Shin, Byung Joo Lee, Yeji Moon, Se-Youp Lee, Dong Cheol Lee, Soon Young Cho, Seong-Joon Kim, Sei Yeul Oh, Sunghyuk Moon, Shin Yeop Oh, Daye Diana Choi, Mi Young Choi, Won Jae Kim, Ungsoo Sa
    Graefe's Archive for Clinical and Experimental Ophthalmology.2023; 261(4): 1127.     CrossRef
  • Alcoholic liver disease in relation to cancer incidence and mortality: Findings from a large, matched cohort study in South Korea
    Thi Phuong Thao Tran, Minji Han, Ngoc Minh Luu, Jin‐Kyoung Oh
    Cancer Medicine.2023; 12(7): 8754.     CrossRef
  • Associations of dual use of tobacco cigarettes and e‐cigarettes, sleep duration, physical activity and depressive symptoms among middle‐aged and older Korean adults
    Mi‐Ae You, JiYeon Choi, Youn‐Jung Son
    Nursing Open.2023; 10(6): 4071.     CrossRef
  • Prevalence, Trend, and Risk Factors for Early Chronic Obstructive Pulmonary Disease: An Analysis of the Nationwide Population-Based Survey from 2010 to 2019 in South Korea
    Taeyun Kim, Hyunji Choi, Ju-il Seo, Seung-Jin Kim, Ji-Eun Choi, Minsu Yun, Jihun Kang
    COPD: Journal of Chronic Obstructive Pulmonary Disease.2023; 20(1): 153.     CrossRef
  • Trends in the Quality of Primary Care and Acute Care in Korea From 2008 to 2020: A Cross-sectional Study
    Yeong Geun Gwon, Seung Jin Han, Kyoung Hoon Kim
    Journal of Preventive Medicine and Public Health.2023; 56(3): 248.     CrossRef
  • Association of handgrip strength with new-onset CKD in Korean adults according to gender
    Sung-Bum Lee, Miryung Kim, Hui-Jeong Lee, Jong-Koo Kim
    Frontiers in Medicine.2023;[Epub]     CrossRef
  • Elevated Uric Acid Levels with Early Chronic Kidney Disease as an Indicator of New-Onset Ischemic Heart Disease: A Cohort of Koreans without Diabetes
    Sung-Bum Lee, Hui-Jeong Lee, Ha Eun Ryu, Byoungjin Park, Dong-Hyuk Jung
    Biomedicines.2023; 11(8): 2212.     CrossRef
  • Clinical and life style factors related to the nighttime blood pressure, nighttime dipping and their phenotypes in Korean hypertensive patients
    Byung Sik Kim, Ju Han Kim, Wan Kim, Woo Shik Kim, Sungha Park, Sang Jae Lee, Jang Young Kim, Eun Mi Lee, Sang Hyun Ihm, Wook Bum Pyun, Jeong-Hun Shin, Jinho Shin
    Clinical Hypertension.2023;[Epub]     CrossRef
  • Combinations of lifestyle behaviors and cancer risk among Korean adults
    Ngoc Minh Luu, Thi Tra Bui, Thi Phuong Thao Tran, Thi Huyen Trang Nguyen, Jin-Kyoung Oh
    Scientific Reports.2023;[Epub]     CrossRef
  • Risk for Esophageal Cancer Based on Lifestyle Factors–Smoking, Alcohol Consumption, and Body Mass Index: Insight from a South Korean Population Study in a Low-Incidence Area
    Mi Jung Kwon, Ho Suk Kang, Hyo Geun Choi, Joo-Hee Kim, Ji Hee Kim, Woo Jin Bang, Sung Kwang Hong, Nan Young Kim, Sangkyoon Hong, Hong Kyu Lee
    Journal of Clinical Medicine.2023; 12(22): 7086.     CrossRef
  • Association of Muscle Strength with Non-Alcoholic Fatty Liver Disease in Korean Adults
    Sung-Bum Lee, Yu-Jin Kwon, Dong-Hyuk Jung, Jong-Koo Kim
    International Journal of Environmental Research and Public Health.2022; 19(3): 1675.     CrossRef
  • Association of Handgrip Strength with Diabetes Mellitus in Korean Adults According to Sex
    Sung-Bum Lee, Ji-Eun Moon, Jong-Koo Kim
    Diagnostics.2022; 12(8): 1874.     CrossRef
  • Smoking trajectory and cancer risk: A population-based cohort study
    Minh Luu, Minji Han, Tra Bui, Phuong Thao Tran, Min-Kyung Lim, Jin Oh
    Tobacco Induced Diseases.2022; 20(August): 1.     CrossRef
  • Awareness of and practice toward cancer prevention recommendations: results of the Korean National Cancer Prevention Awareness and Practice Survey in 2021
    Jin-Kyoung Oh, Eunjung Park, Byungmi Kim, Yoon-Jung Choi, E Hwa Yun, Min Kyung Lim, Jeong-Soo Im, Eun Young Park
    Epidemiology and Health.2022; 44: e2022068.     CrossRef
  • Incidence rate, risk factors and behaviour changes for alcohol drinking: findings from a community-based cohort study in Southwest China
    Bingbing Zhu, Jie Zhou, Yun Chen, Kelin Xu, Yanli Wu, Yiying Wang, Na Wang, Tao Liu, Chaowei Fu
    BMJ Open.2022; 12(9): e060914.     CrossRef
  • Gender and tobacco epidemic in South Korea: implications from age-period-cohort analysis and the DPSEEA framework
    Sera Kim, Garam Byun, Garam Jo, Dahyun Park, Sung-Il Cho, Hannah Oh, Rockli Kim, S V Subramanian, Sungha Yun, Kyungwon Oh, Jong-Tae Lee, Min-Jeong Shin
    BMJ Open.2022; 12(4): e058903.     CrossRef
Alcohol-related emergency department visits and income inequality in New York City, USA: an ecological study
Kathleen H. Reilly, Katherine Bartley, Denise Paone, Ellenie Tuazon
Epidemiol Health. 2019;41:e2019041.   Published online October 8, 2019
DOI: https://doi.org/10.4178/epih.e2019041
  • 23,583 View
  • 183 Download
  • 8 Web of Science
  • 7 Crossref
AbstractAbstract PDF
Abstract
OBJECTIVES
Previous research has found that greater income inequality is related to problematic alcohol use across a variety of geographical areas in the USA and New York City (NYC). Those studies used self-reported data to assess alcohol use. This study examined the relationship between within-neighborhood income inequality and alcohol-related emergency department (ED) visits.
METHODS
The study outcome was the alcohol-related ED visit rate per 10,000 persons between 2010 and 2014, using data obtained from the New York Statewide Planning and Research Cooperative System. The main predictor of interest was income inequality, measured using the Gini coefficient from the American Community Survey (2010-2014) at the public use microdata area (PUMA) level (n=55) in NYC. Variables associated with alcohol-related ED visits in bivariate analyses were considered for inclusion in a multivariable model.
RESULTS
There were 420,568 alcohol-related ED visits associated with a valid NYC address between 2010 and 2014. The overall annualized NYC alcohol-related ED visit rate was 100.7 visits per 10,000 persons. The median alcohol ED visit rate for NYC PUMAs was 88.0 visits per 10,000 persons (interquartile range [IQR], 64.5 to 133.5), and the median Gini coefficient was 0.48 (IQR, 0.45 to 0.51). In the multivariable model, a higher neighborhood Gini coefficient, a lower median age, and a lower percentage of male residents were independently associated with the alcohol-related ED visit rate.
CONCLUSIONS
This study found that higher neighborhood income inequality was associated with higher neighborhood alcohol-related ED visit rates. The precise mechanism of this relationship is not understood, and further investigation is warranted to determine temporality and to assess whether the results are generalizable to other locales.
Summary

Citations

Citations to this article as recorded by  
  • Association of the built environment, demographic and socioeconomic factors with indoor environmental complaints: A community-level study
    Zhao Dong, Zhonghua Gou, Isabelle Y.S. Chan
    Habitat International.2026; 171: 103773.     CrossRef
  • While Some Things Change, Do Others Stay the Same? The Heterogeneity of Neighborhood Health Returns to Gentrification
    Jennifer Candipan, Alicia R. Riley, Janeria A. Easley
    Housing Policy Debate.2023; 33(1): 129.     CrossRef
  • Distribution of the compression and expansion of morbidity in 194 countries and territories, 1990–2016: The role of income inequality
    He Chen, Jing Ning, Hongwei Hu, Haotian He
    Sociology of Health & Illness.2023; 45(7): 1523.     CrossRef
  • Inequality's on Tap: A Longitudinal Study of Area-Level Income Inequality and Alcohol Consumption Among Canadian Adolescents
    Samuel A.J. Lowe, Sujan Basnet, Scott T. Leatherdale, Karen A. Patte, Roman Pabayo
    Journal of Adolescent Health.2023; 73(6): 1093.     CrossRef
  • Variation in intervention stigma among medications for opioid use disorder
    Erin F. Madden, Kristin K. Barker, Joshua Guerra, Corey Villanueva, Sandra H. Sulzer
    SSM - Qualitative Research in Health.2022; 2: 100161.     CrossRef
  • Bayesian Spatio-Temporal Modeling for the Inpatient Hospital Costs of Alcohol-Related Disorders
    Zhen Yu, Keming Yu, Wolfgang K. Härdle, Xueliang Zhang, Kai Wang, Maozai Tian
    Journal of the Royal Statistical Society Series A: Statistics in Society.2022; 185(Supplement): S644.     CrossRef
  • Social vulnerabilities for substance use: Stressors, socially toxic environments, and discrimination and racism
    Hortensia Amaro, Mariana Sanchez, Tara Bautista, Robynn Cox
    Neuropharmacology.2021; 188: 108518.     CrossRef
Association between Metabolic Syndrome and Alcohol drinking and Smoking histories in a rural area of Korea.
Hee Sung Ha, Hyeon Woo Yim, Yong Moon Park, Jin Hee Lee, Seung Hwan Lee, Hyuk Sang Kwon, Kun Ho Yoon, Ho Young Son, Moo Il Kang, Won Chul Lee
Korean J Epidemiol. 2008;30(2):281-293.   Published online December 31, 2008
DOI: https://doi.org/10.4178/kje.2008.30.2.281
  • 12,229 View
  • 43 Download
AbstractAbstract PDF
Abstract
PURPOSE
Prevalence of metabolic syndrome is increasing markedly in rural area of Korea. Alcohol drinking and smoking are the main risk factors which shows the highest prevalence rate among the risk factors of metabolic syndrome. The aim of this study was to investigate the association between metabolic syndrome and alcohol drinking and smoking histories in a rural area of Korea.
METHODS
Data was obtained from 1,332(507 men, 825 women) individuals aged over 40 years who lived in rural area of Chungju city in 2007. Metabolic syndrome was defined by NCEP ATP III criteria and waist circumference was defined by WHO-APR(Asia Pacific Region). Data analysis was carried out using SAS version 8.02.
RESULTS
In men, adjusted odds ratio for metabolic syndrome was 2.78(1.09-7.05) for current alcohol drinker, 2.75(1.38-5.51) for past alcohol drinker, 3.25(1.58-6.67) for under 21 years old at start of alcohol drinking, 2.62(1.12-6.11) for light alcohol drinker, 6.01(2.65-13.64) for heavy alcohol drinker. In women, all the alcohol related risk factors were not statistically significant with metabolic syndrome. For all the smoking related risk factors were not statistically significant with metabolic syndrome in men and women. Adjusted odds ratio of alcohol drinking habits for each components of diagnostic criteria of metabolic syndrome was significant for high blood pressure, high fasting glucose and hypertriglyceridemia in men and abdominal obesity in women. Adjusted odds ratio of cigarette smoking habits for each components of diagnostic criteria of metabolic syndrome was significant for abdominal obesity in women.
CONCLUSION
Controlling alcohol drinking habits in men should be reinforced in order to prevent the metabolic syndrome in a rural area of Korea.
Summary
Cigarette Smoking, Alcohol Consumption, and Breast Cancer in Korea.
Dae Hee Kang, Keun Young Yoo, Sue Kyung Park, Hye Won Koo, Jun Suk Suh, Young Chul Kim, Dong Young Noh, Kuk Jin Choe
Korean J Epidemiol. 1998;20(1):60-69.
  • 9,774 View
  • 32 Download
AbstractAbstract PDF
Abstract
A hospital-based case-control study was conducted to assess the relationship between cigarette smoking, alcohol consumption, and the risk of bgreast cancer in Korea. Histologically confirmed incident cases of breast cancer(n=146) were selected from the inpatients at the Department of Surgery, Seoul National University Hospital and Borame Hospital during 1994 to 1997. Women ithout self-reported past history of any malignandies were regarded as controls and selected at the same hospitals during the same period(n-153). Information on life-styles including cigarette smoking, alcohol drinking, and reproductive history were obtained by direct interview using standardixed questionnaire. Each case was matched with one control by 5-year age category(n=146). Adjusted odds ratios and 90% confidence intervals were estimated by unconditional linear logistic regression model. For smokers, age at first smoking was significantly associated with the breat cancer risk(adjusted OR=14.1, 90% CI=1.24-364.2). Particularly noteworthy was an increasing tendency of the breast cancer risk with the duration of alcohol consumtion in years aong alcohol drinkers(ptrend<0.1). These findings suggest that cigarette smoking at an earlier age and alcohol intake might contribute to the risk factor of breast cancer in Korean women. Further investigation on the association between genetic polymorphism of xenobiotic metabolism enxymes of environmental carcinogens and breast cancer should be needed.
Summary
Epidemiol Health : Epidemiology and Health
© Korean Society of Epidemiology.
TOP