Skip Navigation
Skip to contents

Epidemiol Health : Epidemiology and Health



Page Path
HOME > Search
1 "Erdaw Tachbele"
Article category
Publication year
Original Article
Survival and predictors of mortality among human immunodeficiency virus patients on anti-retroviral treatment at Jinka Hospital, South Omo, Ethiopia: a six years retrospective cohort study
Erdaw Tachbele, Gobena Ameni
Epidemiol Health. 2016;38:e2016049.   Published online November 6, 2016
  • 16,255 View
  • 368 Download
  • 24 Web of Science
  • 11 Crossref
AbstractAbstract PDF
The survival rate of human immunodeficiency virus (HIV)-infected patients receiving treatment in Ethiopia is poorly understood. This study aimed to determine the survival rate and predictors of mortality among HIV-infected adults on antiretroviral therapy (ART) at Jinka Hospital, South Omo, Ethiopia.
A 6-year retrospective cohort study was conducted using 350 patient records drawn from 1,899 patients on ART at Jinka Hospital from September 2010 to August 2015. The data were analyzed using Kaplan-Meier statistics and Cox regression models.
Of the 350 study participants, 315 (90.0%) were censored and 35 (10.0%) died. Twenty-two (62.9%) of the deaths occurred during the first year of treatment. The total follow-up encompassed 1,995 person-years, with an incidence rate of 1.75 deaths per 100 person-years. The mean survival time of patients on highly active antiretroviral therapy (HAART) was 30.84±19.57 months. The overall survival of patients on HAART was 64.00% (95% confidence interval [CI], 61.85 to 66.21%) at 72 months of follow-up. The significant predictors of mortality included non-disclosure of HIV status (adjusted hazard ratio [aHR], 5.82; 95% CI, 1.91 to 17.72), a history of tuberculosis (aHR, 1.82; 95% CI, 1.41 to 3.51), and ambulatory (aHR, 2.97; 95% CI, 1.20 to 8.86) or bedridden (aHR, 4.67; 95% CI, 1.30 to 17.27) functional status, World Health Organization (WHO) clinical stage IV illness (aHR, 24.97; 95% CI, 2.75 to 26.45), and substance abusers (aHR, 3.72; 95% CI, 1.39 to 9.97).
Patients with a history of tuberculosis treatment, ambulatory or bedridden functional status, or advanced WHO clinical stage disease, as well substance abusers, should be carefully monitored, particularly in the first few months after initiating antiretroviral therapy. Patients should also be encouraged to disclose their status to their relatives.


Citations to this article as recorded by  
  • Incidence rate of mortality and its predictors among tuberculosis and human immunodeficiency virus coinfected patients on antiretroviral therapy in Ethiopia: systematic review and meta-analysis
    Nebiyu Mekonnen Derseh, Muluken Chanie Agimas, Fantu Mamo Aragaw, Tilahun Yemanu Birhan, Solomon Gedlu Nigatu, Meron Asmamaw Alemayehu, Tigabu Kidie Tesfie, Tirualem Zeleke Yehuala, Tilahun Nega Godana, Mehari Woldemariam Merid
    Frontiers in Medicine.2024;[Epub]     CrossRef
  • Predictors of Survival Time Among HIV-Infected Adults After Initiating Anti-Retroviral Therapy in Kombolcha Town: A 5-Year Retrospective Cohort Study
    Muhammed Siraj, Sisay Gedamu, Belachew Tegegne
    HIV/AIDS - Research and Palliative Care.2022; Volume 14: 181.     CrossRef
  • Survival and predictors of mortality among HIV-infected adults receiving ART in Hawassa comprehensive specialized hospital, Sidama regional state, Ethiopia
    Balta Bargude, Fanta Amanuel
    Journal of Advanced Pediatrics and Child Health.2022; 5(1): 042.     CrossRef
  • Incidence of Mortality and Its Predictors Among HIV Positive Adults on Antiretroviral Therapy in University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia
    Achamyeleh Birhanu Teshale, Adino Tesfahun Tsegaye, Haileab Fekadu Wolde
    HIV/AIDS - Research and Palliative Care.2021; Volume 13: 31.     CrossRef
  • Statistical Joint Modeling for Predicting the Association of CD4 Measurement and Time to Death of People Living with HIV Who Enrolled in ART, Southwest Ethiopia
    Firew Tiruneh, Lalisa Chewaka, Dinaol Abdissa
    HIV/AIDS - Research and Palliative Care.2021; Volume 13: 73.     CrossRef
  • Rate and Predictors of Mortality Among Adults on Antiretroviral Therapy at Debre Markos Referral Hospital, North West Ethiopia
    Haddis Birhanu, Atsede Alle, Molla Yigzaw Birhanu
    HIV/AIDS - Research and Palliative Care.2021; Volume 13: 251.     CrossRef
  • Predictors of Mortality Among Adult HIV-Infected Patients Taking Antiretroviral Therapy (ART) in Harari Hospitals, Ethiopia
    Abdi Birhanu, Tariku Dingeta, Moti Tolera
    HIV/AIDS - Research and Palliative Care.2021; Volume 13: 727.     CrossRef
  • Epidemiology of survival pattern and its predictors among HIV positive patients on highly active antiretroviral therapy in Southern Ethiopia public health facilities: a retrospective cohort study
    Abewa Kebede, Fasil Tessema, Gadisa Bekele, Zerihun Kura, Hailu Merga
    AIDS Research and Therapy.2020;[Epub]     CrossRef
  • Prognostic Factors of Mortality among Adult Patients on Antiretroviral Therapy in India: A Hospital Based Retrospective Cohort Study
    Nitin Joseph, Ushasti Sinha, Nishtha Tiwari, Pritha Ghosh, Patneedi Sindhu
    BioMed Research International.2019; 2019: 1.     CrossRef
  • Predictors of mortality among adult patients enrolled on Antiretroviral Therapy in Hiwotfana specialized University Hospital, Eastern Ethiopia: Retrospective Cohort study
    Eticha Endalkachew Mekonnen
    Journal of HIV for Clinical and Scientific Research.2018; : 007.     CrossRef
  • Prevalence and Risk Factors of Mortality among Adult HIV Patients Initiating ART in Rural Setting of HIV Care and Treatment Services in North Western Tanzania: A Retrospective Cohort Study
    Daniel Wilfred Gunda, Igembe Nkandala, Semvua Bukheti Kilonzo, Boniface Bartholomew Kilangi, Bonaventura Cornel Mpondo
    Journal of Sexually Transmitted Diseases.2017; 2017: 1.     CrossRef

Epidemiol Health : Epidemiology and Health