Baseline |
|
|
Total(n) |
8,457 |
Demographics: age, sex, village, taluk |
Age (yr) |
30-105 |
Socioeconomic indicators: education, occupation, type of house, number of people at home, number of room at home, land ownership, vehicle ownership, type of latrine, source of drinking water, presence of indoor animals |
Mean±SD (yr) |
45.5±12.5 |
|
Year |
2006-2009 |
Health related (respiratory symptoms) cough, phlegm, breathlessness, wheeze |
|
|
Self-reported diagnosis of respiratory diseases: emphysema, asthma, allergic bronchitis, chronic bronchitis, COPD, lung cancer, tuberculosis |
|
|
Self-reported diagnosis of non-communicable diseases: hypertension, diabetes mellitus, stroke, heart disease |
|
|
Medical history of consultation with doctor or hospitalization: consulted or admitted for breathlessness, days of hospitalization, chest surgeries, hospitalization in childhood for respiratory illness |
|
|
Risk factors for chest disorders: tobacco smoking: type of smoking (beedi, cigarette, both), age of start, years of smoking, frequency, current smoking status, pack years, smoking index |
|
|
Biomass fuel smoke exposure: years of exposure, hours exposed in a day, biomass index |
|
|
Environmental exposure to dust at work, tobacco smoke |
|
|
Type of fuel used for domestic work (kerosene, gas, biomass) presence of chimney and early life events |
|
|
Knowledge and attitudes of smokers towards tobacco smoking and nicotine dependence: Fagerstrom questionnaire (subset n=900) [8,32] |
MUDHRA cohort |
|
|
Total (n) |
1,085 |
Height, weight, body mass index |
Age (yr) |
35-80 |
Lung function: spirometry pre- and post-bronchodilator forced vital capacity, forced expiratory volume in the first second |
Mean±SD (yr) |
49.9±10.5 |
|
Year |
2009-2010 |
|
First follow up |
|
|
Total (n) |
869 |
Respiratory symptom severity indicators: COPD Assessment Test [33], St. Georg’s Respiratory Questionnaire [34], modified Medical Research Council dyspnoea scale [35] |
Age (yr) |
43-90 |
|
Mean±SD (yr) |
60.7±12.9 |
Assessment of physical activity/exercise capacity: six-minute walk distance [36] |
Year |
2014-2016 |
Lung function test (spirometry) pre- and post-bronchodilator forced vital capacity, forced expiratory volume in the first second |
|
|
Mental health: HAM-A [37] and HAM-D [38] scales |
|
|
Serum vitamin D levels (n=200) |
|
|
Serum antioxidant reserves thiobarbituric acid reactive substances and ferric reducing antioxidant power (n=200) |
|
|
Forty serum cytokines and chemokines (n=98) |