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Korean Journal of Epidemiology 1985;7(2): 265-273.
종합건강진단 수진자들에서 나타난 HBsAg 및 Anti-HBs의 양성률과 간기능 검사치와의 관련성에 관한 연구
이세훈, 조창용, 맹광호
A study on the positive rate of HBsAg and Anti-HBs and the relationship between HBsAg positive and some liver function tests among the multiphasic health screening examinees
Se Hoon Lee, Chang Yong Cho, Kwang Ho Meng
Abstract
Because of high positive rate of HBsAg among population, its relationship with liver disease and abnormal liver functions has been an important issue in recent years in Korea. To measure the positive rates of HBsAg and Anti-HBs by different population characteristics and to investigate the relationship of HBsAg positivity with liver functions 2,479 subjects who have visited Multiphasic Health Screening Unit, Kangnam St. Mary's Hospital were studied. The results obtained from this study were as follows: 1) Positive rate of HBsAg of total study subjects was 9.7%, and it was significantly higher in males(10.8%) than in females(7.4%). 2) In male aged 20~29, the positive rate of HBsAg was as high as 16.3, and it was gradually decreased as age increased. In female, however, there was the tendency of increment in positive rate of HBsAg as age increased. Positive rate of HBsAg was the highest in sales and service workers(12.1%) and the lowest in laborers and agricultural workers(8.3%). The difference was even statistically significant. 3) Positive rate of Anti-HBs in all study subjects was 37.4%, and those who revealed negative response both in HBsAg and Anti-HBs were 53.3%. 4) HBsAg positivity was statistically associated with abnormal values of liver function tests, such as SGOT, SGPT and TTT. Those with HBsAg positive have abnormal SGOT, SGPT and TTT odds radios of 2.87,2.67 and 2.70, respectively relative to those with HBsAg negative. These odds ratio was even increased to 4.18, 3.34 and 3.13 respectively if those with HBsAg positive and Anti-HBs negative were compared with those HBsAg negative and Anti-HBs positive.


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