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HOME > Epidemiol Health > Volume 6(1); 1984 > Article
Original Article Analytical studies of internal quality control status in clinical chemistry: total protein, albumin, globulin, and cholesterol
Chang Kyou Lee
Epidemiol Health 1984;6(1):78-84
DOI: https://doi.org/
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An internal quality control status analysis on some biochemistries tested in a University Hospital laboratory, a participating member of the External Quality Control Program, but not maintaining the internal quality control program regularly. The test items were total protein, albumin, globulin and cholesterol, and the period of collective data accumulated was from January to December of 1982. 1. The quality control status of total protein in months of January, July, August, September, October and November exceeded the allowable error of 0.21, and it consequently showed low precision while the plus proportional error in accuracy was noticed. 2. In albumin test, it had shown unstable tendency in months of April, June, July, August, September, October and November exceeding the allowable error of 0.11,consequently, lowering the precision. Its accuracy, with the proportional error in the systematic error, was also unsatisfactory. 3. Both precision and accuracy were out of the acceptable range in globulin test quality control status with the allowable error of 0.19 was exceeded in months of January, February, March, April, August, September and November, and the proportional error in the systematic error caused the unsatisfactory phenomenon in accuracy. 4. Both precision and accuracy were out of the acceptable range in cholesterol test quality control status with the allowable error of 8.6 was exceeded in months of January, April, May, June, August, September and October, and the constant error in the systematic error caused the unsatisfactory phenomenon in accuracy. 5. The standards of the allowable error of four chemistry items was established for the domestic reference. 6. Regressive order of the CV mean values were albumin (4.23%), total protein (4.7%), cholesterol (7.28%) and globulin(9.20%) respectively. 7. The results of tested items that fall out of the acceptable range were 4 in August and September, 3 in January, April, October and November, 2 in June July, and 1 in February, March and May.


Epidemiol Health : Epidemiology and Health