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- Original Article Hepatitis B virus infection rate of orphans
- Sung Kook Lee, Min Hae Yeh, Gi Dog Ahn, Byung Yeol Chun, Chang Eun Kim
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Epidemiol Health 1987;9(2):183-192
DOI: https://doi.org/
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Abstract
To determine the hepatitis B virus (HBV) infection rate of orphans and take preventive measures against the hepatitis B virus, the hepatitis B virus infection rate by age, residence duration in orphanages and residence before admission of 249 orphans(male 143, female 106) in 2 orphanages among 21 orphanages which are located in Busan was analyzed and measured for HBsAg, anti-HBs, and anti-HBc, HBeAg with RPHA and RIA method from April 1 to April 28, 1987. Overall HBsAg positive rate was 6.4% and rate for male (9.1%) was statistically significant higher than that for female (2.8%) (P<0.05). Anti-HBs positive rate was 44.6% (48.3% for male, 39.6% for female) and anti-HBc positive rate that executed orphans of HBsAg and anti-HBs negative was 14.8% (19.7% for male, 9.8% for female). Accordingly the hepatitis B virus infection rate (HBV) was 58.2% and the infection rate for male (65.7%) was higher than that for female (48.1%) (P<0.01). HBsAg positive rate by preschool age (under 5 years old) was 8.7%; elementary school age (6-11 years old), 8.3%; junior school age (12-14 years old), 4.8%; senior school age (15 years and over), 4.4% and preschool children were the highest in HBsAg positive rate. HBV infection rate for 5 years old and under was 30.4%; 52.1% for 6-11 years old; 66.1% for 12-14 years old; 69.1% for 15 years and over and the infection rate was increased as age increased. The infection rate by duration of residence in orphanages was 50.3% for 4 years under; 77.4% for 5-9 years; 80.7% for 10 years above and the infection rate by duration was in proportion to their residence duration. The infection rate by residence before admission was 53.5% for home; 75.5% for orphanages; 57.1% for temporary residence and the orphanage residence group was the highest. HBsAg positive rate among HBsAg poisitive orphans (68.8%) was so high and HBV infection rate of orphans with HBeAg positive person in the same room was 64.1% HBV infection rate of orphans with HBeAg negative person in the same room was 55.1% and orphans who live with HBeAg positive person showed the high positive rate, but there isn’t statistically significant difference. Three orphans among 16 HBsAg positive orphans were the HBV patients and HBsAg positive rate related to the result of liver function test greatly. As result of this study, 58.2% orphans among young aged orphans were infected with the hepatitis B virus, and HBsAg positive rate of workers at restaurant was 40.0% and that of workers at office or room was 27.3%. HBeAg positive rate among HBsAg positive workers in orphanage was 80.8%. HBV infection rate of adults in orphanage was 81.6%. There findings suggest that the high HBV infection rate of orphans should be attributed to the high HBeAg positive rate among workers in orphanage by horizontal transmission of HBV through close personal contact. So it is recommended to test new orphans soon after the admission to the orphanage and immunize all the susceptible orphans. Also it is necessary to observe continually after seperating any HBeAg positive orphans who can infect the other.
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