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HOME > Epidemiol Health > Volume 45; 2023 > Article
Cohort Profile Integrated database-based Screening Cohort for Asian Nomadic descendants in China (Scan-China): Insights on prospective ethnicity-focused cancer screening
Yuelin Yu1orcid , Liying Qiao2orcid , Jing Han2, Weiwei Wang1, Weiwei Kang2, Yunjing Zhang1, Shu Shang2, Ruogu Meng3, Lin Zhuo4, Siyan Zhan1, Yunfeng Xi2orcid , Shengfeng Wang1orcid
Epidemiol Health 2023;45e2023048-0
DOI: https://doi.org/10.4178/epih.e2023048
Published online: April 18, 2023
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1Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, China
2Center for Disease Control and Prevention in Inner Mongolia, Hohhot, China
3National Institute of Health Data Science, Peking University, Beijing, China
4Research Center of Clinical Epidemiology, Peking University Third Hospital, Beijing, China
Corresponding author:  Yunfeng Xi,
Email: xiyunfeng210@163.com
Shengfeng Wang,
Email: shengfeng1984@126.com
Received: 23 November 2022   • Accepted: 29 March 2023
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Abstract

Established in 2017, the Screening Cohort for Asian Nomadic descendants in China (Scan-China) has benefited over 180,000 members of a multi-ethnic population, particularly individuals of Mongolian descent compared with the general population (Han ethnicity), in the Inner Mongolia Autonomous Region, China. This cohort study aims to evaluate the effectiveness of cancer screening and serve as a real-world data platform for cancer studies. The 6 most prevalent cancers in China are considered—namely, breast, lung, colorectal, gastric, liver and esophageal cancer. After baseline cancer risk assessments and screening tests, both active and passive follow-up (based on the healthcare insurance database, cancer registry, the front page of hospital medical records, and death certificates) will be conducted to trace participants’ onset and progression of cancers and other prevalent chronic diseases. Scan-China has preliminarily found a disproportionately lower screening participation rate and higher incidence/mortality rates of esophageal and breast cancer among the Mongolian population than among their Han counterparts. Further research will explore the cancer burden, natural history, treatment patterns, and risk factors of the target cancers.

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