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Epidemiol Health > Volume 41; 2019 > Article
Epidemiology and Health 2019;41: e2019016-0.
DOI: https://doi.org/10.4178/epih.e2019016    Published online April 23, 2019.
Risk factors contributing to the incidence and mortality of acute childhood poisoning in emergency department patients in Iran: a hospital-based casecontrol study
Hamideh Feiz Disfani1  , Mostafa Kamandi2  , Seyed Mohammad Mousavi1  , Sayyed Majid Sadrzadeh1  , Roohie Farzaneh1  , Najme Doolabi1  , Kazem Rahmani3 
1Department of Emergency Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
2Department of Internal Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
3Department of Epidemiology, School of Public Health, Iran University of Medical Sciences, Tehran, Iran
Correspondence  Najme Doolabi ,Email: drnajdoolabi@gmail.com
Received: February 7, 2019  Accepted after revision: April 23, 2019
Abstract
OBJECTIVES:
Since poisoning is one of the most important preventable factors contributing to the hospitalization and death of children who present to emergency departments, this study was carried out to investigate the risk factors contributing to the incidence and mortality of acute childhood poisoning.
METHODS:
This hospital-based case-control study included 243 cases and 489 controls, drawn from daily admissions to the emergency departments of the included hospitals according to the inclusion and exclusion criteria.
RESULTS:
Gastrointestinal poisoning was the most common poisoning type, found in 87.7% of subjects, and medications were the most common cause of poisoning (49.8%). Multiple logistic regression analysis showed that a history of poisoning (odds ratio [OR], 10.44; 95% confidence interval [CI], 5.58 to 19.51; p<0.001) and the availability of poisonous substances (OR, 8.88; 95% CI, 5.41 to 14.56; p<0.001) were among the most important predictors of childhood poisoning. Respiratory poisoning (OR, 6.72; 95% CI, 1.40 to 32.07; p<0.05) and the presence of addiction in the family (OR, 4.54; 95% CI, 1.10 to 18.68; p<0.05) were the most important predictors of mortality among children with poisoning.
CONCLUSIONS:
Addiction and the presence of physical or psychological disorders in family members, a history of poisoning, and the availability of poisonous substances were significantly associated with the incidence of childhood poisoning and resultant mortality.
Keywords: Poisoning, Child, Mortality, Emergency department, Iran


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