Epidemiology and Health

Systematic Reviews

Handgrip strength thresholds associated with metabolic syndrome risk in children and adolescents: a systematic review and meta-analysis: Hye Ah Lee, Seunghee Jun, Hyesook Park; Epidemiol Health. 2024;46:e2024047. Published online April 24, 2024; DOI: https://doi.org/10.4178/epih.e2024047

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Abstract Summary PDF Supplementary Material: Abstract
OBJECTIVES
Certain studies have reported that handgrip strength (HGS) is associated with metabolic health risks in children and adolescents, and some studies have suggested HGS thresholds for identifying poor metabolic health. Therefore, we aimed to determine the HGS thresholds associated with metabolic syndrome (MetS) in children and adolescents through a systematic review.
METHODS
We searched 3 electronic databases from their inception until October 2023 to identify original papers that focused on children and adolescents and assessed their risks of MetS according to specific HGS values. Studies were selected for inclusion through a planned screening process based on specific criteria. The Quality Assessment Tool for Diagnostic Accuracy Studies version 2 (QUADAS-2) was used to evaluate quality, and a meta-analysis was performed using the diagmeta R package to suggest the optimal thresholds.
RESULTS
From the search, 8 studies were selected for this systematic review. For detecting MetS risk, the optimal threshold for HGS (defined as relative HGS by adjusting for body mass) was found to be 0.422, with a sensitivity of 76.7% (95% confidence interval [CI], 64.0 to 85.8) and a specificity of 62.9% (95% CI, 56.9 to 68.5). The stratification analysis by sex resulted in optimal thresholds of 0.416 for boys and 0.376 for girls. Additionally, when the data were stratified by age, the thresholds were 0.356 for children and 0.416 for adolescents.
CONCLUSIONS
Our results provide practical information for detecting high-risk groups and encouraging strength-related activities that may reduce the risk of MetS in children and adolescents.; Summary

Korean summary
- 본 연구는 체계적 고찰 및 메타 분석을 수행하여 아동 및 청소년의 대사 증후군(MetS) 위험을 감지하기 위한 최적의 악력 임계값을 제안했습니다. - 본 연구 결과는 아동 및 청소년의 대사 증후군(MetS) 위험을 줄이기 위해 근력 관련 활동이 필요한 고위험군을 식별하는 데 사용할 수 있으므로 1차 임상 및 공공 의료에 실용적인 정보를 제공합니다.

Key Message
- This study conducted a systematic review and meta-analysis to propose the optimal handgrip strength (HGS) threshold for detecting the risk of metabolic syndrome in children and adolescents. - The results provide practical information for primary clinical and public healthcare, as they can be used to identify high-risk groups in need of strength-related interventions to reduce the risk of metabolic syndrome in children and adolescents.

Dietary intake and cancer incidence in Korean adults: a systematic review and meta-analysis of observational studies: Ji Hyun Kim, Shinyoung Jun, Jeongseon Kim; Epidemiol Health. 2023;45:e2023102. Published online November 30, 2023; DOI: https://doi.org/10.4178/epih.e2023102

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Abstract

Cancer is a major health burden in Korea, and dietary factors have been suggested as putative risk factors for cancer development at various sites. This study systematically reviewed the published literature investigating the associations between dietary factors and cancer incidence among Korean adults, following the Preferred Reporting Items for Systematic Reviews and Meta- Analyses guidelines. We focused on the 5 most studied cancer sites (stomach, colorectum, breast, thyroid, and cervix) as outcomes and dietary exposures with evidence levels greater than limited-suggestive according to the World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) panel’s judgment for any of the cancer sites. This resulted in the inclusion of 72 studies. Pooled estimates of the impact of dietary factors on cancer risk suggested protective associations of fruits and vegetables with risks for gastric cancer (GC), colorectal cancer (CRC), and breast cancer (BC) and dietary vitamin C with the risk of GC, as well as a harmful association between fermented soy products and the risk of GC. Despite the limited number of studies, we observed consistent protective associations of dietary fiber with GC and dietary fiber, coffee, and calcium with CRC. These findings are largely consistent with the WCRF/AICR expert report. However, pooled estimates for the associations of other salt-preserved foods with GC, meat with CRC, and dietary carotenoids and dairy products with BC did not reach statistical significance. Further studies with prospective designs, larger sample sizes, and diverse types of dietary factors and cancer sites are necessary.

Summary

Korean summary
한국 성인을 대상으로 주요 암종 발생과 관련된 식이 요인을 탐색한 72개 역학연구들을 체계적으로 리뷰하고 메타 분석한 결과, 과일 및 채소는 위암, 대장암, 유방암에 대한 보호 효과가 있으며, 식이 비타민 C는 위암 예방에 도움이 된다는 결과가 확인되었다. 반면, 염장 식품 중 발효 대두 제품은 위암 발생 위험을 증가시킬 수 있다. 향후 식이 섭취와 밀접하게 관련되었으나 기존 국내 연구가 부족한 암종과 다양한 식이 요인의 영향을 탐색하는 대규모 전향적 코호트 연구가 요구된다.

Key Message
We conducted a systematic review and meta-analysis on the associations between dietary factors and cancer incidence among Korean adults. Pooled estimates suggested protective associations of fruits and vegetables with risks for gastric cancer (GC), colorectal cancer (CRC), and breast cancer (BC) and dietary vitamin C with the risk of GC, as well as a harmful association between fermented soy products and GC risk. Further research is warranted, emphasizing longitudinal designs, larger sample sizes, and a comprehensive exploration of dietary factors, with a specific focus on anatomical sites with a substantial burden of disease but understudied in the context of diet.

Citations

Citations to this article as recorded by

Genetic evidence of circulating metabolites linking to gastric cancers: a two-sample Mendelian randomization study
Yu Haiwen, Liu Yongjian, Xie Penglong, Feng Wanting, Xu Dongchu
Annals of Medicine & Surgery.2025; 87(2): 571. CrossRef

Special Articles

Evidence integration on health damage for humidifier disinfectant exposure and legal presumption of causation: Mina Ha, Taehyun Park, Jong-Hyun Lee, Younghee Kim, Jungyun Lim, Yong-Wook Baek, Sol Yu, Hyen-Mi Chung, Kyu Hyuck Chung, Hae-Kwan Cheong, Review Committee for the Epidemiological Correlations between Humidifier Disinfectants Exposure and Health Effects; Epidemiol Health. 2023;45:e2023095. Published online October 24, 2023; DOI: https://doi.org/10.4178/epih.e2023095

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Abstract

OBJECTIVES
Inhalation exposure to humidifier disinfectants has resulted to various types of health damages in Korea. To determine the epidemiological correlation necessary for presuming the legal causation, we aimed to develop a method to synthesize the entire evidence.

METHODS

Epidemiological and toxicological studies are systematically reviewed. Target health problems are selected by criteria such as frequent complaints of claimants. Relevant epidemiologic studies are reviewed and the risk of bias and confidence level of the total evidence are evaluated. Toxicological literature reviews are conducted on three lines of evidence including hazard information, animal studies, and mechanistic studies, considering the source-to-exposure-to-outcome continuum. The confidence level of the body of evidence is then translated into the toxicological evidence levels for the causality between humidifier disinfectant exposure and health effects. Finally, the levels of epidemiological and toxicological evidence are synthesized.

RESULTS

Under the Special Act revised in 2020, if the history of exposure and the disease occurred/worsened after exposure were approved, and the epidemiological correlation between the exposure and disease was verified, the legal causation is presumed unless the company proves the evidence against it. The epidemiological correlation can be verified through epidemiological investigations, health monitoring, cohort investigations and/or toxicological studies. It is not simply as statistical association as understood in judicial precedents, but a general causation established by the evidence as a whole, i.e., through weight-of-the-evidence approach.

CONCLUSIONS

The weight-of-the-evidence approach differs from the conclusive single study approach and this systematic evidence integration can be used in presumption of causation.

Summary

Korean summary
저자들은 가습기살균제 노출로 인한 건강피해의 법적 인과관계 추정요건인 역학적 상관관계를 확인하기 위한 과정으로서 체계적 문헌고찰과 역학과 독성학의 전체 과학적 근거를 체계적으로 종합하는 방법을 제시하였다. 이것은 법적 증거 방법에서 개별 연구가 가지는 제한점이나 불확실성을 이유로 배척하지 않고, 전체 증거의 부분으로서 종합적으로 접근하는 것을 통해 사실 관계에 도달하는 방법이다. 이 전체증거접근법은 향후 인과관계 추정에서 전범(model)이 될 수 있다.

Key Message
We establish a systematic method for integrating a body of scientific evidence of epidemiology and toxicology to verify the epidemiological correlation, which is essential for presuming legal causation of health damages due to exposure to humidifier disinfectants. In terms of a legal proof, this method does not exclude individual studies due to their limitations or uncertainty but integrates them as part of a body of evidence to arrive at a conclusion that better reflects the truth of the evidence. This weight-of-the-evidence approach can be a model for future causal inference.

Citations

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Prenatal and Childhood Exposure to Humidifier Disinfectants and Attention-Deficit/Hyperactivity Disorder (ADHD): Insights from a Retrospective Cohort Design
Hyowon Choi, Hunju Lee, Yeon-Soon Ahn
Toxics.2025; 13(2): 78. CrossRef
A systematic review and BMD modeling approach to develop an AOP for humidifier disinfectant-induced pulmonary fibrosis and cell death
Donghyun Kim, Yusun Shin, Jong-In Park, Donghyeon Lim, Hyunjoon Choi, Seongwon Choi, Yong-Wook Baek, Jungyun Lim, Younghee Kim, Ha Ryong Kim, Kyu Hyuck Chung, Ok-Nam Bae
Chemosphere.2024; 364: 143010. CrossRef
Toxicological evidence integration to confirm the biological plausibility of the association between humidifier disinfectant exposure and respiratory diseases using the AEP-AOP framework
Ha Ryong Kim, Jun Woo Kim, Jong-Hyeon Lee, Younghee Kim, Jungyun Lim, Yong-Wook Baek, Sunkyoung Shin, Mina Ha, Hae-Kwan Cheong, Kyu Hyuck Chung
Epidemiology and Health.2024; 46: e2024060. CrossRef

Cancer risk based on alcohol consumption levels: a comprehensive systematic review and meta-analysis: Seunghee Jun, Hyunjin Park, Ui-Jeong Kim, Eun Jeong Choi, Hye Ah Lee, Bomi Park, Soon Young Lee, Sun Ha Jee, Hyesook Park; Epidemiol Health. 2023;45:e2023092. Published online October 16, 2023; DOI: https://doi.org/10.4178/epih.e2023092

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Abstract Summary PDF Supplementary Material

Abstract

OBJECTIVES
Alcohol consumption is a well-established risk factor for cancer. Despite extensive research into the relationship between alcohol consumption and cancer risk, the effect of light alcohol consumption on cancer risk remains a topic of debate. To contribute to this discourse, we conducted a comprehensive systematic review and meta-analysis.

METHODS

Our systematic review aimed to investigate the associations between different levels of alcohol consumption and the risk of several cancer types. We focused on analyzing prospective associations using data from 139 cohort studies. Among them, 106 studies were included in the meta-analysis after a quantitative synthesis.

RESULTS

Our analysis did not find a significant association between light alcohol consumption and all-cause cancer risk (relative risk, 1.02; 95% confidence interval, 0.99 to 1.04), but we observed a dose-response relationship. Light alcohol consumption was significantly associated with higher risks of esophageal, colorectal, and breast cancers. Light to moderate drinking was associated with elevated risks of esophageal, colorectal, laryngeal, and breast cancers. Heavy drinking was also found to contribute to the risk of stomach, liver, pancreas, and prostate cancers, thereby increasing the risk of almost all types of cancer. Additionally, females generally had lower cancer risks compared to males.

CONCLUSIONS

Our findings highlight that cancer risks extend beyond heavy alcohol consumption to include light alcohol consumption as well. These findings suggest that there is no safe level of alcohol consumption associated with cancer risk. Our results underscore the importance of public health interventions addressing alcohol consumption to mitigate cancer risks.

Summary

Korean summary
본 연구는 코호트 연구를 기반으로 하여 음주의 수준에 따른 암 위험 연관성에 대해 체계적 문헌고찰(139편)과 메타분석(106편)을 수행하였다. 연구 결과, 음주와 암 위험 사이에 용량-반응 관계가 나타났으며, 소량의 음주는 암 유형에 따라 차이가 있었으나, 식도암, 대장암, 전립선암(남성), 유방암(여성)에서 암 위험과의 연관성이 있음을 발견했다. 따라서, 암 위험 측면에서 음주에 안전한 수준이 없음을 시사하며, 음주와 관련된 잠재적 피해를 완화하기 위해서는 음주 지침 강화와 같은 공중보건개입이 필요하다.

Key Message
The aim of this study was to assess the relationship between different levels of alcohol consumption and the risk of various cancer types through a systematic review and meta-analysis, providing insights into the ongoing debate about alcohol consumption and cancer causality. The findings support a dose-response relationship between alcohol consumption levels and cancer risk and the light alcohol consumption was associated with risks of esophageal, colorectal, prostate (male), and breast (female) cancer. These results emphasize the absence of a safe threshold for alcohol consumption in terms of cancer risk.

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Associations of lifestyle factors with oral cancer risk: An umbrella review
Haobo Xu, Zhonglan Gao, Hairong Liu, Liya An, Ting Yang, Bojun Zhang, Guobin LIU, Dali Sun
Journal of Stomatology, Oral and Maxillofacial Surgery.2025; : 102234. CrossRef
Estudio bibliométrico de las publicaciones sobre cirugía pancreática realizadas por cirujanos españoles
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Personalized Lifestyle Interventions for Prevention and Treatment of Obesity-Related Cancers: A Call to Action
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Cirugía Española (English Edition).2025;[Epub] CrossRef
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Chengdong Yu, Jiawei Xu, Siyi Xu, Lei Tang, Qinyuan Han, Xiaoqiang Zeng, Yanxiao Huang, Tenghua Yu, Zhengkui Sun
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To Drink or Not to Drink? Investigating Alcohol’s Impact on Prostate Cancer Risk
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Brief Communication

Prevalence and methodological quality of systematic reviews in Korean medical journals: Seong Jung Kim, Mi Ah Han, Jae Hung Jung, Eu Chang Hwang, Hae Ran Kim, Sang Eun Yoon, Seo-Hee Kim, Pius Kim, So-Yeong Kim; Epidemiol Health. 2023;45:e2023017. Published online February 6, 2023; DOI: https://doi.org/10.4178/epih.e2023017

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Abstract

This study aimed to assess and evaluate the prevalence and methodological quality of systematic reviews (SRs) published in major Korean medical journals (KMJs). The top 15 journals with the highest Korean Medical Citation Index, published between 2018 to 2021, were selected. We assessed the methodological quality of SRs using A Measurement Tool to Assess Systematic Reviews 2 (AMSTAR 2). In total, 126 SRs were included, with an average of 32 SRs being reported annually. The overall prevalence of SRs in KMJs was 2.8%, with an increase from 2.6% in 2018 to 3.4% in 2021. Overall, the methodological quality of SRs was low (9.5% low, 90.5% critically low). More than 80% of the studies adhered to critical domain items such as a comprehensive literature search and risk of bias assessment, but for items such as protocol registration and listing excluded studies and the justification for exclusion, the adherence rate was less than 15%. While the number of SRs in KMJs steadily increased, the overall confidence in the methodological quality was low to critically low. Therefore, in order to provide the best evidence for decision-making in clinical and public health areas, editors, reviewers, and authors need to pay more attention to improving the quality of SRs.

Summary

Korean summary
한국의학저널에서 체계적 문헌고찰의 수는 꾸준히 증가했지만 방법론적 품질은 전반적으로 낮았다. 임상 및 공중 보건 분야에서 의사 결정을 위한 최상의 근거를 제공하기 위해 편집자, 심사자 및 저자는 체계적 문헌고찰의 품질을 개선하는 데 더 많은 관심을 기울여야 할 것이다.

Key Message
While the number of systematic reviews in Korean medical journals steadily increased, the overall confidence of methodological quality was low to critically low. Therefore, in order to provide the best evidence for decision-making in clinical and public health areas, editors, reviewers, and authors need to pay more attention to improving the quality of systematic reviews.

Citations

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RETRACTED: A methodological framework for rigorous systematic reviews: Tailoring comprehensive analyses to clinicians and healthcare professionals
Stefano Mancin, Marco Sguanci, Giuliano Anastasi, Lea Godino, Alessio Lo Cascio, Emanuela Morenghi, Michela Piredda, Maria Grazia De Marinis
Methods.2024; 225: 38. CrossRef
The status quo of systematic reviews published in high-impact journals in Korea: a study focused on protocol registration and GRADE use
Mi Ah Han, Seong Jung Kim, Eu Chang Hwang, Jae Hung Jung
Epidemiology and Health.2022; 44: e2022108. CrossRef

Systematic Reviews

Associations of daily diet-related greenhouse gas emissions with the incidence and mortality of chronic diseases: a systematic review and meta-analysis of epidemiological studies: Jee Yeon Hong, Young Jun Kim, Sanghyuk Bae, Mi Kyung Kim; Epidemiol Health. 2023;45:e2023011. Published online December 30, 2022; DOI: https://doi.org/10.4178/epih.e2023011

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Abstract Summary PDF Supplementary Material

Abstract

OBJECTIVES
Although the entire process extending from food production to dietary consumption makes a large contribution to total greenhouse gas (GHG) emissions, little and inconsistent evidence exists on the epidemiological associations of daily diet-related GHG emissions with chronic disease risk or all-cause mortality. This systematic review and meta-analysis explored the observational epidemiological relationship between daily diet-related GHG emissions and health outcomes, including the risk of chronic diseases and all-cause mortality.

METHODS

Original articles published in English until May 2022 were identified by searching PubMed, Ovid-Embase, Web of Science, CINAHL, and Google Scholar. The extracted data were pooled using both fixed-effects and random-effects meta-analyses and presented as hazard and risk ratios (RRs) with 95% confidence intervals (CIs).

RESULTS

In total, 7 cohort studies (21 study arms) were included for qualitative synthesis and meta-analysis. The GHG emissions of dietary consumption showed a significant positive association with the risk of chronic disease incidence and mortality in both fixed-effects and random-effects models (fixed: RR, 1.04; 95% CI, 1.03 to 1.05; random: RR, 1.04; 95% CI, 1.02 to 1.06). This positive association was robust regardless of how daily diet-related GHG emissions were grouped. More strongly animal- based diets showed higher GHG emissions. However, there were only a few studies on specific chronic diseases, and the subgroup analysis showed insignificant results. There was no evidence of publication bias among the studies (Egger test: p=0.79).

CONCLUSIONS

A higher GHG-emission diet was found to be associated with a greater risk of all-cause mortality.

Summary

Korean summary
식이로부터 배출되는 GHG양은 메타분석의 고정 효과 모델과 확률 효과 모델 모두에서 만성 질환 발병률 및 사망 위험과 유의미한 양의 상관 관계를 보여주었습니다. 동물성 식단은 더 높은 GHG 배출량을 나타냈으나, 특정 만성질환에 대한 연구의 수가 적었고 질환 별 하위군 분석에서 유의미한 결과를 보이지 않았습니다. 결론적으로 온실가스 배출량이 많은 식단은 모든 원인으로 인한 사망 위험이 더 큰 것으로 나타났습니다.

Key Message
Daily food consumption contributes a large part of greenhouse gas (GHG) emissions, however, no review study was conducted. This study is the first review paper that reviews the relationship between greenhouse gas (GHG) emissions from daily diet and chronic disease risk and all-cause mortality. GHG emissions from the daily diet were significantly positively associated with disease risk and mortality. Animal-based diets contributed most to diet-derived GHG emissions. Men tended to have diets with higher GHG emissions compared to women. At times when the response to climate change is urgent, this study can help many policymakers and health officials.

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The bounds of meta-analytics and an alternative method
Ramalingam Shanmugam, Mohammad Tabatabai, Derek Wilus, Karan P. Singh
Epidemiology and Health.2024; 46: e2024016. CrossRef
Association between Diet-Related Greenhouse Gas Emissions and Mortality among Japanese Adults: The Japan Collaborative Cohort Study
Daiki Watanabe, Kotatsu Maruyama, Akiko Tamakoshi, Isao Muraki
Environmental Health Perspectives.2024;[Epub] CrossRef

The status quo of systematic reviews published in high-impact journals in Korea: a study focused on protocol registration and GRADE use: Mi Ah Han, Seong Jung Kim, Eu Chang Hwang, Jae Hung Jung; Epidemiol Health. 2022;44:e2022108. Published online November 15, 2022; DOI: https://doi.org/10.4178/epih.e2022108

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Abstract Summary PDF Supplementary Material: Abstract
OBJECTIVES
This study investigated the status quo of systematic reviews published in major journals in Korea from the perspective of protocol registration and adopting the grading of recommendation, assessment, development and evaluation (GRADE) system.
METHODS
We examined systematic reviews published in Korea’s top 15 medical journals from 2018 to 2021. Teams of 2 reviewers assessed the studies’ eligibility criteria and extracted data independently and in duplicate. We collected information on study characteristics, protocol registration, and GRADE use of the included reviews, and reviewed the “Instructions for Authors” of the selected journals to assess any guidance related to systematic reviews.
RESULTS
Out of the 126 identified reviews, 18 (14.3%) reported that they registered or published their protocol. Only 5 (4.0%) rated the certainty of evidence; and all 5 used the GRADE system. Only 6 of 15 journals mentioned systematic reviews in their “Instructions for Authors.” Six journals endorsed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) framework for systematic review reporting (2 mandatory, 3 recommended, and 1 unclear). None of the journals included mentioned protocol registration or certainty of evidence in their authors’ guidelines.
CONCLUSIONS
Overall, the proportion of systematic reviews that had prior protocol registration or used the GRADE approach to rate the certainty of evidence was very low. Our study highlights the need for adherence to systematic review standards in medical journals in Korea, including prior protocol registration and certainty of evidence assessment. Our review will help improve the quality of systematic reviews in Korea.; Summary

Korean summary
한국 의학 저널에서 계획서를 사전에 등록하거나 근거의 확실성을 평가하기 위해 GRADE 접근 방식을 사용한 체계적 문헌고찰의 분율은 낮았다. 우리의 연구는 계획서 등록 및 근거의 확실성 평가를 포함하여 체계적 문헌고찰의 방법론적 표준 준수의 필요성을 강조한다.

Key Message
The proportion of systematic reviews that had prior protocol registration or used the GRADE approach to rate the certainty of evidence was very low in Korean medical journals, and our study highlights the need for adherence to systematic review standards in medical journals in Korea, including prior protocol registration and certainty of evidence assessment.

Methods

Meta-analysis of diagnostic test accuracy studies with multiple thresholds for data integration: Sung Ryul Shim; Epidemiol Health. 2022;44:e2022083. Published online September 28, 2022; DOI: https://doi.org/10.4178/epih.e2022083

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Abstract Summary PDF Supplementary Material

Abstract

OBJECTIVES
The objective of this study is to introduce methods to use all of the information without omission when individual studies provide multiple effect sizes according to multiple cut-off values (thresholds) during diagnostic test accuracy (DTA) for data integration. For diagnostic test meta-analysis, a general performance method for synthesizing data according to one cut value in one study and a performance method for synthesizing data according to two or more cut values in one study were compared and analyzed.

METHODS

As sample data for meta-analysis of DTA studies, 13 DTA studies on prostate cancer (34 effect sizes including total cut-offs) were collected. The summary statistics were calculated and the summary line was analyzed using the “meta”, “mada”, and “diagmeta” packagesof the R software.

RESULTS

The summary statistics of the random effect model univariate analysis of the “meta” package with a single cut-off corresponding to the highest Youden index in a single study and those of the bivariate analysis of the “mada” package were highly similar. However, in the bivariate analysis of the “diagmeta” package including all cut-off values, the sensitivity decreased and the specificity increased as the amount of data increased.

CONCLUSIONS

Considering the heterogeneity of the summary receiver op erating characteristic curve and the use of all given cut-offs, the use of the bivariate analysis model of the “diagmeta” package is recommended. This study focused on practical methods of DTA rather than theoretical concepts for use by researchers whose fields of study are non-statistics related. By performing this study, we hope that many researchers will use R software to determine the DTA more easily, and that there will be greater interest in related research.

Summary

Korean summary
본 연구는 진단검사 메타분석시 개별 대상연구가 다수의 기준치 (cut-off value, threshold)에 따른 여러 개의 효과크기를 제공하고 있을 때, 정보의 누락없이 이를 모두 사용하는 방법과 더불어 기존의 수행방법도 비교 분석하였기에 연구에 적합한 모델 선택에 도움이 될 것이다.

Key Message
The objective of this study is to introduce methods to use all of the information without omission when indi¬vidual studies provide multiple effect sizes according to multiple cut-off values (thresholds) during diagnostic test accuracy (DTA) for data integration.

Citations

Citations to this article as recorded by

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Systematic Review

Quantifying the duration of the preclinical detectable phase in cancer screening: a systematic review: Sandra M. E. Geurts, Anne M. W. M. Aarts, André L. M. Verbeek, Tony H. H. Chen, Mireille J. M. Broeders, Stephen W. Duffy; Epidemiol Health. 2022;44:e2022008. Published online January 3, 2022; DOI: https://doi.org/10.4178/epih.e2022008

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443 Download
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Abstract Summary PDF Supplementary Material

Abstract

OBJECTIVES
The aim of this study was to provide an overview of published mathematical estimation approaches to quantify the duration of the preclinical detectable phase (PCDP) using data from cancer screening programs.

METHODS

A systematic search of PubMed and Embase was conducted for original studies presenting mathematical approaches using screening data. The studies were categorized by mathematical approach, data source, and assumptions made. Furthermore, estimates of the duration of the PCDP of breast and colorectal cancer were reported per study population.

RESULTS

From 689 publications, 34 estimation methods were included. Five distinct types of mathematical estimation approaches were identified: prevalence-to-incidence ratio (n=8), maximum likelihood estimation (n=16), expectation-maximization algorithm (n=1), regression of observed on expected (n=6) and Bayesian Markov-chain Monte Carlo estimation (n=5). Fourteen studies used data from both screened and unscreened populations, whereas 19 studies included only information from a screened population. Estimates of the duration of the PCDP varied between 2 years and 7 years for breast cancer in the Health Insurance Plan study (annual mammography and clinical breast examinations in women aged 40-64 years) and 2 years and 5 years for colorectal cancer in the Calvados study (a guaiac fecal occult blood test in men and women aged 45-74 years).

CONCLUSIONS

Different types of mathematical approaches lead to different estimates of the PCDP duration. We advise researchers to use the method that matches the data available, and to use multiple methods for estimation when possible, since no method is perfect.

Summary

Key Message
Quantifying the duration of the preclinical detectable phase is important for the design and evaluation of cancer screening programs. Different types of mathematical estimation approaches lead to different estimates of the preclinical detectable phase duration. We advise researchers to use the method that matches the data available, and to use multiple methods for estimation when possible, since no method is perfect.

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COVID-19: Original Article

The role of vitamin D deficiency on COVID-19: a systematic review and meta-analysis of observational studies: Mehmet Onur Kaya, Esra Pamukçu, Burkay Yakar; Epidemiol Health. 2021;43:e2021074. Published online September 23, 2021; DOI: https://doi.org/10.4178/epih.e2021074

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Abstract Summary PDF Supplementary Material

Abstract

OBJECTIVES
Although vaccination has started, coronavirus disease 2019 (COVID-19) poses a continuing threat to public health. Therefore, in addition to vaccination, the use of supplements to support the immune system may be important. The purpose of this study was to synthesize evidence on the possible effect of low serum vitamin D levels (25[OH]D<20 ng/mL or 50 nmol/L) on COVID-19 infection and outcomes.

METHODS

We searched Google Scholar, PubMed, Scopus, Web of Science, and ScienceDirect without any language restrictions for articles published between January 1 and December 15, 2020. We performed 3 meta-analyses (called vitamin D and COVID-19 infection meta-analysis [D-CIMA], vitamin D and COVID-19 severity meta-analysis [D-CSMA], and vitamin D and COV ID-19 mortality meta-analysis [D-CMMA] for COVID-19 infection, severity, and mortality, respectively) to combine odds ratio values according to laboratory measurement units for vitamin D and the measured serum 25(OH)D level.

RESULTS

Twenty-one eligible studies were found to be relevant to the relationship between vitamin D and COVID-19 infection/outcomes (n=205,869). The D-CIMA meta-analysis showed that individuals with low serum vitamin D levels were 1.64 times (95% confidence interval [CI], 1.32 to 2.04; p<0.001) more likely to contract COVID-19. The D-CSMA meta-analysis showed that people with serum 25(OH)D levels below 20 ng/mL or 50 nmol/L were 2.42 times (95% CI, 1.13 to 5.18; p=0.022) more likely to have severe COVID-19. The D-CMMA meta-analysis showed that low vitamin D levels had no effect on COVID-19 mortality (OR, 1.64; 95% CI, 0.53 to 5.06, p=0.390).

CONCLUSIONS

According to our results, vitamin D deficiency may increase the risk of COVID-19 infection and the likelihood of severe disease. Therefore, we recommend vitamin D supplementation to prevent COVID-19 and its negative outcomes.

Summary

Key Message
Although vaccination has started, it seems that Covid-19 will continue to threaten public health for a long time. In addition to the vaccine, the use of supplements to support the immune system may also be important. The purpose of this study is to indicate the possible effect of low serum vitamin D (25(OH)D<20 ng/mL or 50nmol/L) on the Covid-19 infection and outcomes. According to our remarkable results, vitamin D deficiency increases the risk of Covid-19 infection and the potential for the severity of the disease. Therefore, vitamin D supplements should be added to prevention and treatment protocols for Covid-19 disease.

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COVID-19: Systematic Review

Mental health outcomes of quarantine and isolation for infection prevention: a systematic umbrella review of the global evidence: Md Mahbub Hossain, Abida Sultana, Neetu Purohit; Epidemiol Health. 2020;42:e2020038. Published online June 2, 2020; DOI: https://doi.org/10.4178/epih.e2020038

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Abstract PDF Supplementary Material

Abstract

Objectives
Transmission of infectious diseases is often prevented by quarantine and isolation of the populations at risk. These approaches restrict the mobility, social interactions, and daily activities of the affected individuals. In recent coronavirus disease 2019 (COVID-19) pandemic, quarantine and isolation are being adopted in many contexts, which necessitates an evaluation of global evidence on how such measures impact the mental health outcomes among populations. This umbrella review aimed to synthesize the available evidence on mental health outcomes of quarantine and isolation for preventing infectious diseases.

Methods

We searched nine major databases and additional sources and included articles if they were systematically conducted reviews, published as peer-reviewed journal articles, and reported mental health outcomes of quarantine or isolation in any population.

Results

Among 1,364 citations, only eight reviews met our criteria. Most of the primary studies in those reviews were conducted in high-income nations and in hospital settings. These articles reported a high burden of mental health problems among patients, informal caregivers, and healthcare providers who experienced quarantine or isolation. Prevalent mental health problems among the affected individuals include depression, anxiety, mood disorders, psychological distress, posttraumatic stress disorder, insomnia, fear, stigmatization, low self-esteem, lack of self-control, and other adverse mental health outcomes.

Conclusions

This umbrella review found severe mental health problems among individuals and populations who have undergone quarantine and isolation in different contexts. This evidence necessitates multipronged interventions including policy measures for strengthening mental health services globally and promoting psychosocial wellbeing among high-risk populations.

Summary

Citations

Citations to this article as recorded by

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Breastfeeding Practices and Postpartum Depression in Mexican Women during the COVID-19 Pandemic: A Cross-Sectional Study
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A Survey of Changes in the Psychological State of Individuals with Social Withdrawal (hikikomori) in the Context of the COVID Pandemic
Takafumi Ogawa, Yuki Shiratori, Haruhiko Midorikawa, Miyuki Aiba, Daichi Sugawara, Naoaki Kawakami, Tetsuaki Arai, Hirokazu Tachikawa
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A social network analysis: mental health scales used during the COVID-19 pandemic
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Piloting a new method to estimate action thresholds in medicine through intuitive weighing
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The influences of dormitory exercise on negative emotions among quarantined Chinese college students during the COVID-19 pandemic
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Frontiers in Psychiatry.2023;[Epub] CrossRef
Change in the form of work of psychologists after the outbreak of the COVID-19 pandemic in Poland, and the subjective mental state of this professional group
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International Journal of Occupational Safety and Ergonomics.2023; 29(4): 1552. CrossRef
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Psychosocial and Economic Risks of Institutional Quarantine in a Low-Resource Setting: Experiences of Affected Persons during the COVID-19 Pandemic in Uganda
Esther K. Nanfuka, Agatha Kafuko, Rita Nakanjako, James T. Ssenfuuma, Florence Turyomurugyendo, Jingo Kasule
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Depressive Disorders of Polish University Students During the Covid-19 Pandemic
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COVID-19—Evidence of the Impact of Literacy and Salutogenic Behaviours in Positive Mental Health: A Cross-Sectional Study
Cláudia Almeida, André Novo, Maria Lluch Canut, Carme Ferré-Grau, Carlos Sequeira
Behavioral Sciences.2023; 13(10): 845. CrossRef
Depressive Disorders of Polish University Students During the Covid-19 Pandemic
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قدرة القلق والاكتئاب واضطراب ما بعد الصدمة على التنبؤ بإدمان مواقع التواصل الاجتماعي لدى طلبة الجامعة في ظل جائحة كورونا
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Association of COVID-19 Infection with Sociodemographic, Anthropometric and Lifestyle Factors: A Cross-Sectional Study in an Older Adults’ Population Aged over 65 Years Old
Eleni Pavlidou, Sousana K. Papadopoulou, Georgios Antasouras, Theofanis Vorvolakos, Olga Alexatou, Gerasimos Tsourouflis, Exakousti-Petroula Angelakou, Aspasia Serdari, Maria G. Grammatikopoulou, Evmorfia Psara, Konstantinos Vadikolias, Antonios Dakanalis
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Biopsychosocial Profile of COVID-19 Patients Cared for in Public and Private Health Facilities in Kandahar Province, Afghanistan
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Prevalence of Obesity and Lifestyle Risk Factors Following Two Years’ COVID-19 Related Service Closure at Wellness Center, Primary Health Care
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Psychological Impact of COVID-19 and Its Influence on Parental Willingness to Vaccinate Children: A Cross-Sectional Study at a Tertiary Care Hospital in Kolkata
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The impact of COVID-19 and the confinement on the secondary level students of the Eastern region of Morocco
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SAÚDE MENTAL E PANDEMIA: Avaliação dos níveis de ansiedade e depressão em pessoas que tiveram Covid-19 no município de Sobral-CE
Francisco Thiago Paiva Monte, Roberlandia Evangelista Lopes Ávila, Hermínia Maria Sousa da Ponte, Percy Antonio Galimbertti Catanio
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Impact of the COVID-19 pandemic on the Thai population: Delineating the effects of the pandemic and policy measures
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Anxiety and Depressive Symptoms among Discharged COVID-19 Patients from Isolation Centers in North-Central, Nigeria: A Cross-sectional Study
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Exploring the Relationship Between Self-Isolation and Distress Among People with Gastrointestinal Disorders During the COVID-19 Pandemic
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The postpartum period during the COVID-19 pandemic: investigating Turkish women’s postpartum support and postpartum-specific anxiety
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Psychological Burden and Associated Factors of the COVID-19 Pandemic on People in Quarantine and Isolation Centers in Ethiopia: A Cross-Sectional Study
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The Trend of Psychiatric Visits and Psychiatric Medication Prescription Among People Tested for SARS-CoV-2 During the Initial Phase of COVID-19 Pandemic in South Korea
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Evaluating a psychological support service focused on the needs of critical care and theatres staff in the first wave of COVID-19
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How Long Does Adaption Last for? An Update on the Psychological Impact of the Confinement in Portugal
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The Impact of Long COVID-19 on Mental Health: Observational 6-Month Follow-Up Study
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Promoting Flight Crew Mental Health Requires International Guidance for Down-Route Quarantine Circumstances
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Impact of the COVID-19 pandemic on BMI: Its changes in relation to socio-demographic and physical activity patterns based on a short period
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Workplace Factors, Burnout Signs, and Clinical Mental Health Symptoms among Mental Health Workers in Lombardy and Quebec during the First Wave of COVID-19
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Evaluating a psychological support service focused on the needs of critical care and theatre staff in the first wave of COVID-19
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Factors Predicting Practices in Prevention of COVID-19 and Impacts among Population in Chiang Mai, Thailand
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The Burden of the Pain: Adverse Mental Health Outcomes of COVID-19 in Women With and Without Cancer
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Dihydromyricetin improves social isolation-induced cognitive impairments and astrocytic changes in mice
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Effect of Neuromuscular Training Program on Quality of Life After COVID-19 Lockdown Among Young Healthy Participants: A Randomized Controlled Trial
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Anxiety, Depression, and Other Emotional Disorders during the COVID-19 Pandemic: A Narrative Review of the Risk Factors and Risk Groups
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Perceived Changes in Emotions, Worries and Everyday Behaviors in Children and Adolescents Aged 5–18 Years with Type 1 Diabetes during the COVID-19 Pandemic
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The Psychological Impact of Quarantine During the COVID-19 Pandemic on Quarantined Non-Healthcare Workers, Quarantined Healthcare Workers, and Medical Staff at the Quarantine Facility in Saudi Arabia
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Mental Wellbeing and Boosting Resilience to Mitigate the Adverse Consequences of the COVID-19 Pandemic: A Critical Narrative Review
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Prevalence and Factors Associated with Insomnia in Military Personnel: A Retrospective Study during the Second COVID-19 Epidemic Wave in Peru
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The Impact of SARS-CoV-2 (COVID-19) on the Acuity of Mental Health–Related Diagnosis at Admission for Young Adults in New York City and Washington, DC: Observational Study
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Quality of Life of Older Adults with Physical and Mobility Disabilities during the COVID-19 Pandemic: A Cross-Sectional Study in Thailand
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Analyses of Social Issues and Public Policy.2022; 22(3): 817. CrossRef
Anxiety, Distress and Stress among Patients with Diabetes during COVID-19 Pandemic: A Systematic Review and Meta-Analysis
Rubén A. García-Lara, José L. Gómez-Urquiza, María José Membrive-Jiménez, Almudena Velando-Soriano, Monserrat E. Granados-Bolivar, José L. Romero-Béjar, Nora Suleiman-Martos
Journal of Personalized Medicine.2022; 12(9): 1412. CrossRef
COVID-19 neuropsychiatric repercussions: Current evidence on the subject
Ronaldo Teixeira da Silva Júnior, Jonathan Santos Apolonio, Beatriz Rocha Cuzzuol, Bruna Teixeira da Costa, Camilo Santana Silva, Glauber Rocha Lima Araújo, Marcel Silva Luz, Hanna Santos Marques, Luana Kauany de Sá Santos, Samuel Luca Rocha Pinheiro, Vin
World Journal of Methodology.2022; 12(5): 365. CrossRef
Health Behaviors and Associated Feelings of Remote Workers During the COVID-19 Pandemic—Silesia (Poland)
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Frontiers in Public Health.2022;[Epub] CrossRef
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Translational Psychiatry.2022;[Epub] CrossRef
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Jung-Hoon Lee, Seri Maeng, Jeong-Seop Lee, Jae-Nam Bae, Won-Hyoung Kim, Hyeyoung Kim
Journal of the Korean Academy of Child and Adolescent Psychiatry.2022; 33(4): 113. CrossRef
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National Journal of Community Medicine.2022; 13(09): 642. CrossRef
Individual-based modeling reveals that the COVID-19 isolation period can be shortened by community vaccination
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Frontiers in Psychology.2022;[Epub] CrossRef
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Petra Engelmann, Bernd Löwe, Thomas Theo Brehm, Angelika Weigel, Felix Ullrich, Marylyn M. Addo, Julian Schulze zur Wiesch, Ansgar W. Lohse, Anne Toussaint
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The significant transformation of life into health and beauty in metaverse era
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Journal of Cosmetic Dermatology.2022; 21(12): 6575. CrossRef
Key features of a trauma-informed public health emergency approach: A rapid review
Christina L. Heris, Michelle Kennedy, Simon Graham, Shannon K. Bennetts, Caroline Atkinson, Janine Mohamed, Cindy Woods, Richard Chennall, Catherine Chamberlain
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Psychological Status of College Students During COVID-19 Pandemic: A Cross-Sectional Study in Saudi Arabia
Mona Alanazi
Advances in Medical Education and Practice.2022; Volume 13: 1443. CrossRef
The Influence of COVID-19 on University Students’ Well-Being, Physical Activity, Body Composition, and Strength Endurance
Robert Podstawski, Kevin John Finn, Krzysztof Borysławski, Aneta Anna Omelan, Anna Maria Podstawska, Andrzej Robert Skrzypczak, Andrzej Pomianowski
International Journal of Environmental Research and Public Health.2022; 19(23): 15680. CrossRef
Self-Care for Nurses and Midwives: Findings from a Scoping Review
Luisa Sist, Sara Savadori, Annalisa Grandi, Monica Martoni, Elena Baiocchi, Carlotta Lombardo, Lara Colombo
Healthcare.2022; 10(12): 2473. CrossRef
Lower Back Pain Caused by the Impact of COVID-19 Quarantine on Physical Activity and Daily Sitting Among Adult Saudi Arabian Populations in Jeddah: A Cross-Sectional Study
Lutf Ahmed Abumunaser, Kawther Ali Alfaraj, Lujain Khalid Kamal, Renad Abdullah Alzahrani, Maram Misfer Alzahrani, Alzahraa Bader AlAhmed
Orthopedic Research and Reviews.2022; Volume 14: 477. CrossRef
Baseline emotional state influences on the response to animated short films: A randomized online experiment
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Personality Trait Changes in Athletic Training Students during Their University Career: Effects of Academic Stress or COVID-19 Pandemic?
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Journal of Clinical Medicine.2022; 12(1): 269. CrossRef
The COVID-19 Pandemic Between Bio-Ethics, Bio-Law and Bio-Politics: A Case Study on The Italian Experience of The DuPre Commission
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ETHICS IN PROGRESS.2022; 13(2): 90. CrossRef
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Madhu Kharel, Jennifer Lisa Sakamoto, Rogie Royce Carandang, Shinejil Ulambayar, Akira Shibanuma, Ekaterina Yarotskaya, Milana Basargina, Masamine Jimba
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Physical Activity, Dietary Behavior, and Body Weight Changes during the COVID-19 Nationwide Level 3 Alert in Taiwan: Results of a Taiwanese Online Survey
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Effect of the Coronavirus Disease 2019 Pandemic on Suicide-Related Trauma Burden at a Level 1 Trauma Center
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FOOD INTAKE, FOOD PURCHASING ACCESS, AND STRESS DURING THE COVID-19 PANDEMIC: A DESCRIPTIVE STUDY AMONG COLLEGE STUDENTS OF JENDERAL SOEDIRMAN UNIVERSITY
Izka Sofiyya Wahyurin, Ajeng Dian Purnamasari, Hiya Alfi Rahmah
Media Gizi Indonesia.2022; 17(1): 70. CrossRef
Adolescence and COVID-19: Traumatic Stress and Social Distancing in the Italian Epicenter of Pandemic
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European Archives of Psychiatry and Clinical Neuroscience.2021; 271(2): 223. CrossRef
Impacts of COVID-19 pandemic on urban park visitation: a global analysis
Dehui (Christina) Geng, John Innes, Wanli Wu, Guangyu Wang
Journal of Forestry Research.2021; 32(2): 553. CrossRef
Correlates of insomnia among the adults during COVID19 pandemic: evidence from an online survey in India
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The Journal of General Psychology.2021; 148(3): 226. CrossRef
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PPmP - Psychotherapie · Psychosomatik · Medizinische Psychologie.2021; 71(02): 61. CrossRef
COVID-19 pandemisinin yetişkinlerin diyet davranışları, fiziksel aktivite ve stres düzeyleri üzerine etkisi
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Globale Auswirkungen der COVID-19-Pandemie auf die Versorgung von Menschen mit psychischen Erkrankungen
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Der Nervenarzt.2021; 92(6): 556. CrossRef
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COVID-19 and Personality: A Cross-Sectional Multicenter Study of the Relationship Between Personality Factors and COVID-19-Related Impacts, Concerns, and Behaviors
Mahmoud K. AL-Omiri, Ibrahim A. Alzoubi, Abdullah A. Al Nazeh, Abdallah K. Alomiri, Mohannad N. Maswady, Edward Lynch
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Health, Psycho-Social Factors, and Ageism in Older Adults in Spain during the COVID-19 Pandemic
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Exercise and Use of Enhancement Drugs at the Time of the COVID-19 Pandemic: A Multicultural Study on Coping Strategies During Self-Isolation and Related Risks
Artemisa R. Dores, Irene P. Carvalho, Julius Burkauskas, Pierluigi Simonato, Ilaria De Luca, Roisin Mooney, Konstantinos Ioannidis, M. Ángeles Gómez-Martínez, Zsolt Demetrovics, Krisztina Edina Ábel, Attila Szabo, Hironobu Fujiwara, Mami Shibata, Alejandr
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Journal of Korean Neuropsychiatric Association.2021; 60(1): 11. CrossRef
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Souhail Hermassi, Maha Sellami, Ahmad Salman, Abdulla S. Al-Mohannadi, El Ghali Bouhafs, Lawrence D. Hayes, René Schwesig
International Journal of Environmental Research and Public Health.2021; 18(6): 3093. CrossRef
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Barnaby N. Zoob Carter, Ian D. Boardley, Katinka van de Ven
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Changes in health status, workload, and lifestyle after starting the COVID-19 pandemic: a web-based survey of Japanese men and women
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Environmental Health and Preventive Medicine.2021;[Epub] CrossRef
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Nicola Magnavita, Giovanni Tripepi, Carlo Chiorri
International Journal of Environmental Research and Public Health.2021; 18(7): 3330. CrossRef
The Italians in the Time of Coronavirus: Psychosocial Aspects of the Unexpected COVID-19 Pandemic
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Frontiers in Psychiatry.2021;[Epub] CrossRef
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Ines Testoni, Chiara Franco, Enrica Gallo Stampino, Erika Iacona, Robert Crupi, Claudio Pagano
Frontiers in Psychology.2021;[Epub] CrossRef
Effects of Home Confinement on the Intensity of Physical Activity during the COVID-19 Outbreak in Team Handball According to Country, Gender, Competition Level, and Playing Position: A Worldwide Study
Souhail Hermassi, El Ghali Bouhafs, Nicola Luigi Bragazzi, Shiro Ichimura, Khaled E. Alsharji, Lawrence D. Hayes, René Schwesig
International Journal of Environmental Research and Public Health.2021; 18(8): 4050. CrossRef
Is Watching TV Series an Adaptive Coping Strategy During the COVID-19 Pandemic? Insights From an Italian Community Sample
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Frontiers in Psychiatry.2021;[Epub] CrossRef
A cross-sectional study of psychological distress in patients hospitalized for COVID-19
Srilakshmi Pingali, Ajay Kumar Joopaka, Pradeep Sharma Telkapalli, Molanguri Umashankar
Archives of Mental Health.2021; 22(1): 4. CrossRef
Effects of Interoceptive Sensibility on Mental Health during the Coronavirus Disease 2019 Pandemic
Naho Suzuki, Tetsuya Yamamoto, Chigusa Uchiumi, Nagisa Sugaya
International Journal of Environmental Research and Public Health.2021; 18(9): 4616. CrossRef
Psychological impact of infection with SARS-CoV-2 on health care providers
Vidya Venkatesh, Vijay Nirup Samyuktha, Benny Paul Wilson, Dheeraj Kattula, Jayaprakash Russell Ravan
Journal of Family Medicine and Primary Care.2021; 10(4): 1666. CrossRef
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Frontiers in Psychiatry.2021;[Epub] CrossRef
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Frontiers in Public Health.2021;[Epub] CrossRef
Daily hassles and depressive symptoms among COVID-19 home quarantined Chinese university students: The moderating effects of negative cognitive styles
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Journal of Psychology in Africa.2021; 31(2): 124. CrossRef
Changes in physical activity and sleep habits among adults in Russian Federation during COVID-19: a cross-sectional study
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BMC Public Health.2021;[Epub] CrossRef
Mental Disorders of Bangladeshi Students During the COVID-19 Pandemic: A Systematic Review
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Psychology Research and Behavior Management.2021; Volume 14: 645. CrossRef
Suicide and Suicidal Behaviors in the Context of COVID-19 Pandemic in Bangladesh: A Systematic Review
Mohammed A Mamun
Psychology Research and Behavior Management.2021; Volume 14: 695. CrossRef
Impact of COVID-19 Institutional Isolation Measures on Postnatal Women in Level 3 COVID Facility in Northern India
Manisha Gupta, Neelima Agarwal, Alpana G Agrawal
Journal of South Asian Federation of Obstetrics and Gynaecology.2021; 13(1): 50. CrossRef
MENTAL HEALTH CHALLENGES, RESILIENCE AND COPING STYLE CONTRIBUTING TO THE WELL BEING OF PATIENTS RECOVERED FROM COVID - 19.
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PARIPEX INDIAN JOURNAL OF RESEARCH.2021; : 60. CrossRef
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Australian and New Zealand Journal of Public Health.2021; 45(4): 325. CrossRef
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Frontiers in Psychiatry.2021;[Epub] CrossRef
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Physical education of students.2021; 25(3): 158. CrossRef
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European Journal of Psychotraumatology.2021;[Epub] CrossRef
The Experience of Patients with COVID-19 in China: An Interpretative Phenomenological Analysis
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Psychology Research and Behavior Management.2021; Volume 14: 877. CrossRef
Differences Between the Psychiatric Symptoms of Healthcare Workers Quarantined at Home and in the Hospital After Contact With a Patient With Middle East Respiratory Syndrome
Su Jeong Seong, Hyung Joon Kim, Kyung Mi Yim, Ji Won Park, Kyung Hoon Son, Yeong Ju Jeon, Jae Yeon Hwang
Frontiers in Psychiatry.2021;[Epub] CrossRef
Impact of COVID-19 Pandemic on Sleep Quality, Stress Level and Health-Related Quality of Life—A Large Prospective Cohort Study on Adult Danes
Maria Didriksen, Thomas Werge, Janna Nissen, Michael Schwinn, Erik Sørensen, Kaspar R. Nielsen, Mie T. Bruun, Karina Banasik, Thomas F. Hansen, Christian Erikstrup, Sisse R. Ostrowski, Poul J. Jennum, Henrik Hjalgrim, Henrik Ullum, Ole B. Pedersen
International Journal of Environmental Research and Public Health.2021; 18(14): 7610. CrossRef
COVID-19 Fear, Resilience, Social Support, Anxiety, and Suicide among College Students in Spain
Jesús Muyor-Rodríguez, Francisco Caravaca-Sánchez, Juan Sebastián Fernández-Prados
International Journal of Environmental Research and Public Health.2021; 18(15): 8156. CrossRef
Family perceptions related to isolation during COVID-19 hospitalization
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Active Coping and Anxiety Symptoms during the COVID-19 Pandemic in Spanish Adults
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International Journal of Environmental Research and Public Health.2021; 18(16): 8240. CrossRef
Towards an In-Depth Understanding of Physical Activity and Eating Behaviours during COVID-19 Social Confinement: A Combined Approach from a Portuguese National Survey
Marlene Nunes Silva, Maria João Gregório, Rute Santos, Adilson Marques, Bruno Rodrigues, Cristina Godinho, Catarina Santos Silva, Romeu Mendes, Pedro Graça, Miguel Arriaga, Graça Freitas
Nutrients.2021; 13(8): 2685. CrossRef
COVID-19’a Yakalanma Kaygısı İle Fiziksel Aktiviteye Katılım Motivasyonu Arasındaki İlişkinin İncelenmesi
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Frontiers in Psychiatry.2021;[Epub] CrossRef
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International Journal of Environmental Research and Public Health.2021; 18(18): 9758. CrossRef
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Risk Management and Healthcare Policy.2021; Volume 14: 4051. CrossRef
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International Journal of Environmental Research and Public Health.2021; 18(19): 10305. CrossRef
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Systematic Review

Food frequency questionnaires developed and validated in Iran: a systematic review: Arezoo Rezazadeh, Nasrrin Omidvar, Katherine L. Tucker; Epidemiol Health. 2020;42:e2020015. Published online March 30, 2020; DOI: https://doi.org/10.4178/epih.e2020015

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308 Download
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Abstract PDF

Abstract

OBJECTIVES
To systematically review and identify food frequency questionnaires (FFQs) developed for the Iranian population and their validation and reproducibility in order to determine possible research gaps and needs.

METHODS

Studies were selected by searching for relevant keywords in the PubMed, Scopus, Science Direct, Google Scholar, SID, and Iranmedex databases, unpublished data, and theses in November 2016 (updated in September 2019). All English-language and Persian-language papers were included. Duplicates, articles with unrelated content, and articles only containing a protocol were excluded. The FFQs were categorized based on: (1) number of food items in to short (≤80 items) and long (>80 items) and; (2) the aim of the FFQ to explore total consumption pattern/nutrients (general) or to detect specific nutrient(s)/food group(s) (specialized).

RESULTS

Sixteen reasonably validated questionnaires were identified. However, only 13 presented a reproducibility assessment. Ten FFQs were categorized as general (7 long, 3 short) and 6 as specialized (3 long, 3 short). The correlation coefficients for nutrient intake between dietary records or recalls and FFQs were 0.07-0.82 for long (general: 0.07-0.82 and specialized: 0.26-0.67) and 0.20-0.67 for short (general: 0.24-0.54 and specialized: 0.20-0.42) FFQs. Long FFQs showed higher validity and reproducibility than short FFQs. Reproducibility of FFQs was acceptable (0.32-0.89). The strongest correlations were reported by studies with shorter intervals between FFQs.

CONCLUSIONS

FFQs designed for the Iranian population appear to be appropriate tools for dietary assessment. Despite their acceptable reproducibility, their validity for assessing specific nutrients and their applicability for populations other than those they were developed for may be questionable.

Summary

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Reviews

A systematic review and meta-analysis of the genetic characterization of human echinococcosis in Iran, an endemic country: Abolghasem Siyadatpanah, Davood Anvari, Amir Emami Zeydi, Seyed Abdollah Hosseini, Ahmad Daryani, Shahabeddin Sarvi, Christine M. Budke, Reza Esmaeelzadeh Dizaji, Mohammad Ali Mohaghegh, Mohammad Hasan Kohansal, Samira Dodangeh, Reza Saberi, Shirzad Gholami; Epidemiol Health. 2019;41:e2019024. Published online June 15, 2019; DOI: https://doi.org/10.4178/epih.e2019024

18,738 View
335 Download
18 Web of Science
17 Crossref

Abstract PDF

Abstract

Human echinococcosis is an infectious disease caused by tapeworms belonging to the species Echinococcus. This parasite has a worldwide distribution and is considered a neglected tropical disease by the World Health Organization. Due to the diversity of Echinococcus spp. hosts, as well as variation in geographical, climatic, and socio-ethnic conditions, the question of the strains or genotypes of Echinococcus spp. that are involved in human infections is important. The aim of this study was to provide a summary of the available data on genotypes of Echinococcus obtained from the Iranian population. Four international databases (PubMed, Scopus, Science Direct, and Web of Science) and 4 Persian databases (Magiran, Scientific Information Database, Iran Medex, and IranDoc) were searched for cross-sectional studies that reported the genotypes of Echinococcus spp. in human echinococcosis cases using molecular methods in Iran through July 2018. The Newcastle-Ottawa Scale was used to assess the quality of the selected studies. A total of 559 cases of human cystic echinococcosis were reported in the 21 included articles. The majority of cases belonged to genotype G1 (89.2%; 95% confidence interval [CI], 80.1 to 95.8), genotype G6 (8.2%; 95% CI, 2.8 to 15.9), and genotype G3 (2.3%; 95% CI, 1.1 to 3.9). Since genotype G1 of Echinococcus appears to be the most prevalent genotype affecting humans in Iran, disease control initiatives aimed at sheep intermediate hosts may be the most beneficial. In addition, educational programs and serological screening in individuals may help reduce the national impact of the disease.

Summary

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Protective factors of marital stability in long-term marriage globally: a systematic review: Reza Karimi, Maryam Bakhtiyari, Abbas Masjedi Arani; Epidemiol Health. 2019;41:e2019023. Published online June 15, 2019; DOI: https://doi.org/10.4178/epih.e2019023

59,519 View
844 Download
31 Web of Science
34 Crossref

Abstract PDF

Abstract

OBJECTIVES
In recent decades, due to the high prevalence of divorce in numerous countries and the detrimental aftermath thereof, it has become increasingly important to study the components of marital stability. The current study explored fundamental protective factors in long-term marriage through a systematic review.

METHODS

Searches for relevant publications were conducted in Embase, Web of Science, PubMed, Scopus, Science Direct, Magiran, and Scientific Information Database from their inception through January 30, 2019. Through the keyword search, 1,706 articles were found, of which 25 articles remained after screening based on the eligibility criteria.

RESULTS

The extracted protective factors associated with marital stability in long-term marriage were classified as interpersonal and intrapersonal. Notable extracted factors included spirituality and religion, commitment, sexual relationship, communication, children, love and attachment, intimacy, and conflict resolution approach. These findings show that some aspects of relationships, such as commitment, act to preserve the pillars of marriage in critical situations, while other aspects, such as intimacy, help to construct marital identity and satisfaction.

CONCLUSIONS

The identified components of marital stability are structures that enhance a couple’s identity and sense of togetherness. Identifying the specific aspects of marital relationships that contribute to marital stability may help specialists and researchers to target specific types of marital interaction that may enhance the happiness and longevity of relationships, thereby preventing avoidable divorces.

Summary

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Congenital toxoplasmosis among Iranian neonates: a systematic review and meta-analysis: Shahabeddin Sarvi, Tooran Nayeri Chegeni, Mehdi Sharif, Mahbobeh Montazeri, Seyed Abdollah Hosseini, Afsaneh Amouei, Zahra Hosseininejad, Davood Anvari, Reza Saberi, Shaban Gohardehi, Ahmad Daryani; Epidemiol Health. 2019;41:e2019021. Published online May 17, 2019; DOI: https://doi.org/10.4178/epih.e2019021

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Abstract

Toxoplasmosis is a serious zoonotic disease that can lead to abortion and congenital disorders and has a widespread global distribution in humans and animals. The objective of this review was to investigate the incidence of toxoplasmosis in Iranian neonates in order to obtain a comprehensive assessment of the overall situation of the disease for use in developing future interventions. Original studies investigating the incidence of Toxoplasma gondii infections in Iranian neonates were systematically searched in a number of English-language and Persian-language electronic databases. The search process resulted in the inclusion of a total of 11 studies in the systematic review, 10 of which were entered into the meta-analysis. The reviewed articles included 2,230 Iranian neonates investigated through January 1, 2018. Based on the retrieved studies, the overall weighted incidence rates of toxoplasmosis in the Iranian neonatal population and neonates with suspected congenital toxoplasmosis were estimated to be 0.64% (95% confidence interval [CI], 0.31 to 1.09) and 4.10% (95% CI, 2.68 to 5.77), respectively, using a fixed-effects model. The findings of the reviewed studies demonstrate that the incidence of toxoplasmosis is high in Iranian neonates. Accordingly, it can be concluded that toxoplasmosis is a serious public health concern that has been ignored by the Ministry of Health. Therefore, it is essential to perform further studies, in addition to implementing screening and detection programs, using standardized methods to estimate the incidence of toxoplasmosis in Iran and to determine its associated risk factors.

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