Key Message
• This study examined leptospirosis patterns in Kelantan, Malaysia, from 2016 to 2023, highlighting distinct regional varia- tions in disease incidence.
• Case densities were high in the northern region, whereas incidence demonstrated higher risk in the central and southern regions.
• The study underscores the importance of considering both geographic location and population dynamics when planning interventions and allocating resources for disease control.
• The evident spatial clustering highlights the need for targeted public health interventions.