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Sensitization to common allergens among patients with allergies in major Iranian cities: a systematic review and meta-analysis
Mozhgan Moghtaderi, Saeed Hosseini Teshnizi, Shirin Farjadian
Epidemiol Health. 2017;39:e2017007.   Published online February 5, 2017
  • 13,889 View
  • 283 Download
  • 6 Citations
AbstractAbstract PDF
Various allergens are implicated in the pathogenesis of allergic diseases in different regions. This study attempted to identify the most common allergens among patients with allergies based on the results of skin prick tests in different parts of Iran. Relevant studies conducted from 2000 to 2016 were identified from the MEDLINE database. Six common groups of allergen types, including animal, cockroach, food, fungus, house dust mite, and pollen were considered. Subgroup analysis was performed to determine the prevalence of each type of allergen. The Egger test was used to assess publication bias. We included 44 studies in this meta-analysis. The overall prevalence of positive skin test results for at least one allergen was estimated to be 59% in patients with allergies in various parts of Iran. The number of patients was 11,646 (56% male and 44% female), with a mean age of 17.46±11.12 years. The most common allergen sources were pollen (47.0%), mites (35.2%), and food (15.3%). The prevalence of sensitization to food and cockroach allergens among children was greater than among adults. Pollen is the most common allergen sensitization in cities of Iran with a warm and dry climate; however, sensitization to house dust mites is predominant in northern and southern coastal areas of Iran.
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  • Patterns of allergen sensitization in patients with asthma in Yaqui Valley, Mexico
    Diego Hazael Ramirez-Leyva, Leticia Díaz-Sánchez, Maria Citlaly-Ochoa, Jose Manuel Ornelas-Aguirre
    Journal of Asthma.2022; 59(7): 1319.     CrossRef
  • Change in sensitization to inhalant allergens in adults with respiratory allergic disease in Busan and Gyeongsangnam-do province
    Chan Sun Park, Eun-Jung Jo, Mi-Yeong Kim, Young-Hee Nam, Seung-Eun Lee, Gil-Soon Choi, Yi-Yeong Jeong, Hee-Kyoo Kim, Jae-Won Oh, Hye-Kyung Park
    Allergy, Asthma & Respiratory Disease.2022; 10(3): 172.     CrossRef
  • Sensitization to Common Allergens Among Children with Asthma and Allergic Rhinitis in Qatar
    Khalid Zahraldin, Prem Chandra, Amjad Tuffaha, Mohammad Ehlayel
    Journal of Asthma and Allergy.2021; Volume 14: 287.     CrossRef
  • The Fertility Outcome of Royal Jelly versus Intra Uterine Insemination: A Pilot Randomized Controlled Trial Study
    Tahereh Fathi Najafi, Nayereh Khadem, Narjes Bahri, Mojtaba Meshkat, Shirin Sadri, Sareh Dashti
    Jundishapur Journal of Natural Pharmaceutical Products.2021;[Epub]     CrossRef
  • ¿Son las mascotas, perro o gato, un factor de riesgo o protector para el desarrollo o exacerbación del asma? Revisión sistemática de revisiones sistemáticas
    Oscar Alberto Rojas Sánchez
    Revista de Salud Pública.2020; 22(1): 1.     CrossRef
  • Association of molds and metrological parameters to frequency of severe asthma exacerbation
    Mona Al-Ahmad, Edin Jusufovic, Nermina Arifhodzic, Tito Rodriguez, Jasmina Nurkic
    Allergy, Asthma & Clinical Immunology.2019;[Epub]     CrossRef
Methodological issues for determining intervals of subsequent cancer screening
Jong-Myon Bae
Epidemiol Health. 2014;36:e2014010.   Published online July 30, 2014
  • 15,789 View
  • 136 Download
  • 4 Citations
AbstractAbstract AbstractSummary PDFSupplementary Material
The gap between nationwide recommendations of cancer screening and the related evidences obtained from Korean adults should be filled. Estimation of the mean sojourn time (MST) in a specific cancer is important to determine the intervals of subsequent screening. This author arranged the methods for calculating MST into 5 categories based on the parameters used. Under the legal barrier for protection of individual privacy and confidentiality in a Korean academic situation, the methods involving the use of transition rates or prevalence/incidence ratio would be applicable among these methods.
Korean summary
국가 암조기 검진사업에서 제시하는 검진지침은 우리나라 국민을 대상으로 한 역학연구 결과에 근거하여 개발해야 한다. 특정 암에 대한 조기검진 지침에는 검진방법, 시작 및 종료 연령과 함께 검사 주기를 담아야 한다. 이중 반복검사의 간격은 해당 암의 평균체류기간을 산출하여 결정한다. 저자는 특정 암의 평균체류기간을 구하는 방법을 5가지로 분류하여 제시하였다. 또한 현재 개인정보 보호를 강조하는 여건에서 수행이 가능한 방법을 검토하였다.
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  • Quantifying the duration of the preclinical detectable phase in cancer screening: a systematic review
    Sandra M. E. Geurts, Anne M. W. M. Aarts, André L. M. Verbeek, Tony H. H. Chen, Mireille J. M. Broeders, Stephen W. Duffy
    Epidemiology and Health.2022; 44: e2022008.     CrossRef
  • Optimal Interval for Repeated Gastric Cancer Screening in Normal-Risk Healthy Korean Adults: A Retrospective Cohort Study
    Jong-Myon Bae, Sang Yop Shin, Eun Hee Kim
    Cancer Research and Treatment.2015; 47(4): 564.     CrossRef
  • Narrative Reviews
    Jong-Myon Bae
    Epidemiology and Health.2014; : e2014018.     CrossRef
  • Endoscopic Gastric Cancer Screening and Surveillance in High-Risk Groups
    Il Ju Choi
    Clinical Endoscopy.2014; 47(6): 497.     CrossRef
Original Articles
The Validity and Reliability of Characterizing Epilepsy Based on an External Review of Medical Records
Bong Su Kang, Hae-Kwan Cheong, Ki-Young Jung, Sang Hyeon Jang, Jae Kook Yoo, Dong Wook Kim, Soo-Eun Chung, Seo-Young Lee
Epidemiol Health. 2013;35:e2013006.   Published online August 23, 2013
  • 15,405 View
  • 120 Download
  • 9 Citations
AbstractAbstract PDF

Our goal is to validate diagnosing and characterizing epilepsy based on a medical record survey by external reviewers.


We reviewed medical records from 80 patients who received antiepileptic drugs in 2009 at two hospitals. The study consisted of two steps; data abstraction by certified health record administrators and then verification by the investigators. The gold standard was the results of the survey performed by the epileptologists from their own hospital.


The specificity was more than 90.0% for diagnosis and activity, and for new-onset seizures. The sensitivity was 97.0% or more for diagnosis and activity and 66.7-75.0% for new-onset epilepsy. This method accurately classified epileptic syndromes in 90.2-92.9% of patients, causes in 85.4-92.7%, and age of onset in 78.0-81.0%. Kappa statistics for inter-rater reliability and test-retest reliability ranged from 0.641-0.975, which means substantial to near-perfect agreement in all items.


Our data suggest that epilepsy can be well identified by external review of medical records. This method may be useful as a basis for large-scale epidemiological research.

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  • Risk of COVID-19 Infection and of Severe Complications Among People With Epilepsy
    Joonsang Yoo, Jee Hyun Kim, Jimin Jeon, Jinkwon Kim, Tae-Jin Song
    Neurology.2022; 98(19): e1886.     CrossRef
  • The association between early childhood onset epilepsy and attention-deficit hyperactivity disorder (ADHD) in 3237 children and adolescents with Autism Spectrum Disorder (ASD): a historical longitudinal cohort data linkage study
    Lauren Carson, Valeria Parlatini, Tara Safa, Benjamin Baig, Hitesh Shetty, Jacqueline Phillips-Owen, Vibhore Prasad, Johnny Downs
    European Child & Adolescent Psychiatry.2022;[Epub]     CrossRef
  • The bumpy road to achieve reliability of clinical profile characteristics in psychosis and related disorders
    Steven Berendsen, Mirjam J. van Tricht, Amy Tedja, Thijs J. Burger, Mariken B. de Koning, Lieuwe de Haan
    International Journal of Methods in Psychiatric Research.2021;[Epub]     CrossRef
  • Staging and profiling for schizophrenia spectrum disorders: Inter-rater reliability after a short training course
    Steven Berendsen, Jasper W. van der Paardt, Henricus L. Van, Marion van Bruggen, Hans Nusselder, Margje Jalink, Olav R. de Peuter, Jaap Peen, Mirjam J. van Tricht, Lieuwe de Haan
    Progress in Neuro-Psychopharmacology and Biological Psychiatry.2020; 99: 109856.     CrossRef
  • The new definition and classification of seizures and epilepsy
    Jessica J. Falco-Walter, Ingrid E. Scheffer, Robert S. Fisher
    Epilepsy Research.2018; 139: 73.     CrossRef
  • Presentation and management of community-onset vs hospital-onset first seizures
    Emma Foster, Sarah Holper, Zhibin Chen, Patrick Kwan
    Neurology: Clinical Practice.2018; 8(5): 421.     CrossRef
  • Estimating the Prevalence of Treated Epilepsy Using Administrative Health Data and Its Validity: ESSENCE Study
    Seo-Young Lee, Soo-Eun Chung, Dong Wook Kim, So-Hee Eun, Hoon Chul Kang, Yong Won Cho, Sang Do Yi, Heung Dong Kim, Ki-Young Jung, Hae-Kwan Cheong
    Journal of Clinical Neurology.2016; 12(4): 434.     CrossRef
  • Early Antiretroviral Therapy Is Protective Against Epilepsy in Children With Human Immunodeficiency Virus Infection in Botswana
    David Bearden, Andrew P. Steenhoff, Dennis J. Dlugos, Dennis Kolson, Parth Mehta, Sudha Kessler, Elizabeth Lowenthal, Baphaleng Monokwane, Gabriel Anabwani, Gregory P. Bisson
    JAIDS Journal of Acquired Immune Deficiency Syndromes.2015; 69(2): 193.     CrossRef
  • Clinical characteristics of patients with treated epilepsy in Korea: A nationwide epidemiologic study
    Dong Wook Kim, Seo-Young Lee, Soo-Eun Chung, Hae-Kwan Cheong, Ki-Young Jung
    Epilepsia.2014; 55(1): 67.     CrossRef
Diagnostic accuracy of conventional Pap test, liquid-based cytology and human papillomavirus DNA testing in cervical cancer screening in Korea: a meta-analysis.
Jin Kyoung Oh, Hai Rim Shin, Gyungyub Gong, Jin Hee Sohn, Shin Kwang Khang
Korean J Epidemiol. 2008;30(2):178-187.   Published online December 31, 2008
  • 58,436 View
  • 59 Download
  • 4 Citations
AbstractAbstract PDF
Objective: The aim of this study was to compare the diagnostic accuracy of the Pap test, liquid-based cytology (LBC), and human papillomavirus (HPV) testing used as screening methods for the early detection of cervical cancer in Korea. Materials and Methods: Articles reporting the sensitivity and specificity of each screening method that were published between 1995 and March 2008 were retrieved from MEDLINE and KoreaMed. A meta-analysis was conducted to calculate pooled estimates for the sensitivity and specificity of each method. Only cases with histological confirmation were included, and cervical cancer was defined as samples exhibiting cervical intraepithelial neoplasia 2 or worse. In cytological tests, findings of atypical squamous cells of undetermined significance or worse were considered positive.
Of the 24 studies, 15 studies of the Pap test, 3 studies of LBC, and 4 studies of HPV met the inclusion criteria and were included in the meta-analysis. The meta-analysis showed that the sensitivity was highest for LBC (92%), followed by HPV testing (83%) and the Pap test (76%), and the specificity of LBC was the highest (79%), followed by the Pap test (76%) and HPV testing (59%). However, except for the sensitivity of LBC (heterogeneity p-value = 0.682), significant heterogeneity was found among the results of the studies (heterogeneity p-value < 0.0001).
Due to the significant heterogeneity among the studies, the results of this meta-analysis are limited in representing the accuracy of each test method. The accuracy and cost-effectiveness of cervical cancer screening methods should be further evaluated.
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Citations to this article as recorded by  
  • A prospective pilot evaluation of vaginal and urine self-sampling for the Roche cobas 4800 HPV test for cervical cancer screening
    Sang-Hyun Hwang, Hye Young Shin, Dong Ock Lee, Na Young Sung, Bomyee Lee, Do-Hoon Lee, Jae Kwan Jun
    Scientific Reports.2018;[Epub]     CrossRef
  • Comparison of Unsatisfactory Samples from Conventional Smear versus Liquid-Based Cytology in Uterine Cervical Cancer Screening Test
    Hoiseon Jeong, Sung Ran Hong, Seoung-Wan Chae, So-Young Jin, Hye Kyoung Yoon, Juhie Lee, Eun Kyung Kim, Sook Tai Ha, Sung Nam Kim, Eun-Jung Park, Jong Jae Jung, Sun Hee Sung, Sung-chul Lim
    Journal of Pathology and Translational Medicine.2017; 51(3): 314.     CrossRef
  • The performance of multimodal hyperspectral spectroscopy in the detection of precancerous cervical lesions
    Trahmono, N Lusiana, J Indarti
    Journal of Physics: Conference Series.2017; 884: 012152.     CrossRef
  • Usefulness of anti-phosphohistone H3 immunoreactivity to determine mitotic rate in gastrointestinal stromal tumors
    Ahrong Kim, Dong Han Im, Kyungbin Kim, Jee Yeon Kim, Mee Young Sol, Jeong Hee Lee, Kyung Un Choi
    Basic and Applied Pathology.2012; 5(4): 91.     CrossRef

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