Epidemiology and Health

Original Articles

Age- and disability-based trends in potentially preventable hospitalizations: evidence from nationwide claims data in Korea: Hyejung Yoon, Boyoung Jeon, Seyune Lee, Daesung Choi, Se-Youn Jung, Dong-Min Son, Yong Joo Rhee, Juhyeon Moon, So Youn Park, In-Hwan Oh, Young-il Jung; Epidemiol Health. 2026;48:e2026012. Published online February 27, 2026; DOI: https://doi.org/10.4178/epih.e2026012

2,696 View
109 Download

Abstract Summary PDF Supplementary Material: Abstract
OBJECTIVES
Individuals with disabilities are at greater risk of hospitalization than the general population. We examined 10-year trends in potentially preventable hospitalizations (PPH) in Korea, comparing individuals with and without disabilities and assessing age-specific patterns.
METHODS
Using National Health Information Database claims data (2010–2019), we established a fixed cohort of newly registered individuals with disabilities and control subjects statistically matched (1:1.5) at baseline. Annual PPH rates among patients with each condition were calculated and age- and sex-standardized according to Organization for Economic Cooperation and Development Health Care Quality Indicators definitions. Trends and annual percent changes (APCs) were analyzed by disability status and age group (non-older: 30–64; older adults: ≥65 years).
RESULTS
Between 2010 and 2019, PPH rates declined significantly in both groups. Among individuals with disabilities, the steepest decline was observed for hypertension (APC, −15.7%; 95% confidence interval [CI], −17.7 to −13.7), whereas congestive heart failure showed the largest reduction among individuals without disabilities (APC, −7.8%; 95% CI, −10.8 to −4.7). Declines were generally greater among non-older adults aged 30–64 years, regardless of disability status. The disparity between disability and non-disability groups narrowed over the decade, primarily due to larger improvements among non-older adults. Older adults with disabilities consistently exhibited the highest PPH rates for most conditions, whereas younger individuals with disabilities had the highest rates for diabetes.
CONCLUSIONS
PPH rates declined over the decade among both individuals with and without disabilities, particularly for hypertension and among non-older adults. However, older adults with disabilities remain at elevated risk, underscoring the need for targeted strategies to improve access to community-based primary care.; Summary

Korean summary
2010–2019년 한국의 예방가능입원(PPH)은 장애인·비장애인 모두에서 감소했으며, 특히 고혈압과 65세 미만에서 가장 두드러졌다. 장애인-비장애인 간 격차는 감소하고 있으나 여전히 존재했고, 특히 당뇨와 고령 장애인에서 두드러졌다. 이러한 격차의 감소에도 불구하고 고령 장애인이 직면한 높은 PPH 위험은 지속되고 있으며, 이는 지역사회 중심의 일차의료 접근성을 강화하기 위한 맞춤형 전략 수립이 시급함을 시사한다.

Key Message
This study examined trends in potentially preventable hospitalizations (PPH) in Korea from 2010 to 2019,comparing individuals with and without disabilities. Overall, PPH rates declined in both groups, with the largest reductions observed for hypertension and among adults aged 30–64 years. Disability-related disparities also narrowed over time; however, they persisted, particularly for diabetes and among older adults with disabilities. Despite narrowing disparities, the persistently high PPH risk among older adults with disabilities underscores the urgent need for targeted strategies to enhance access to community-based primary care.

Associations between usual source of care characteristics and health outcomes in diabetes mellitus: a focus on medication adherence and healthy behaviors in Korea: Seung Eun Lee, Chul-Woung Kim, Ji Eun Bae, Jee Hyun Choi; Epidemiol Health. 2025;47:e2025063. Published online December 2, 2025; DOI: https://doi.org/10.4178/epih.e2025063

3,068 View
80 Download
1 Crossref

Abstract

OBJECTIVES
This study investigated the associations between usual source of care (USC) characteristics, which incorporate primary care functions, and medication adherence and healthy behaviors in Korean adults with diabetes.

METHODS

We used data from 1,543 adults with diabetes in the 2020 Korea Health Panel Survey. USC was categorized into 5 types based on whether a regular doctor was identified and whether that provider fulfilled comprehensiveness and coordination functions. Multivariable logistic regression was used to assess associations with medication adherence and healthy behaviors.

RESULTS

A significant difference in medication adherence was observed by USC type, although no significant associations emerged for healthy behaviors (smoking, drinking, exercise). Compared to the group without a USC, patients whose regular doctor fulfilled either function were 2.38 times more likely to adhere (odds ratio [OR], 2.38; 95% confidence interval [CI], 1.70 to 3.32), and those whose doctor fulfilled both functions were 1.84 times more likely to adhere (OR, 1.84; 95% CI, 1.31 to 2.59). This association was particularly strong for adherence to medication dosage, frequency, and timing.

CONCLUSIONS

The findings underscore that the functional quality of the USC, particularly the fulfillment of comprehensiveness and coordination, is crucial in improving medication adherence. Simply having a USC is insufficient. The lack of association with healthy behaviors suggests that physicians may focus more on pharmacological control, highlighting the need for multifaceted interventions.

Summary

Korean summary
본 연구는 단순히 주치의가 있는 것만으로는 당뇨병 환자의 복약 순응에 불충분하며, 일차 의료 기능을 충실히 수행하는 상용치료원만이 복약 순응과 유의한 관련이 있음을 입증했습니다. 하지만 상용치료원이 건강 행동 개선과는 관련이 없음을 확인하여, 의료진이 생활 습관 개선에는 영향을 주지 못하고 있음을 시사했습니다. 이러한 결과는 만성질환 관리를 개선하기 위해 상용치료원의 일차 의료 기능을 강화해야 한다는 정책적 근거를 제공합니다.

Key Message
This study shows that simply having a usual source of care (USC) is insufficient; only USCs that fully perform primary care functions are significantly associated with better medication adherence in diabetic patients. However, USC was not linked to improved health behaviors, suggesting providers fail to influence lifestyle changes. The findings provide policy evidence to reinforce the primary care functions of USCs to enhance chronic disease management.

Citations

Citations to this article as recorded by

Association Between Usual Source of Care Types and Health Behaviors: Smoking Cessation, Alcohol Abstinence, and Physical Activity
Jeong-Hee Kang, Chul-Woung Kim
Research in Community and Public Health Nursing.2026; 37: 101. CrossRef

Prospective associations between psychosocial stress and the risk of type 2 diabetes in middle-aged adults: findings from the KoGES_CAVAS: Ji Eun Kim, Hye Won Woo, Yu-Mi Kim, Min-Ho Shin, Sang Baek Koh, Mi Kyung Kim; Epidemiol Health. 2025;47:e2025061. Published online October 31, 2025; DOI: https://doi.org/10.4178/epih.e2025061

3,563 View
112 Download

Abstract Summary PDF Supplementary Material: Abstract
OBJECTIVES
Psychosocial stress is a potential risk factor for type 2 diabetes (T2D); however, the influence of the timing of stress exposure remains uncertain. We examined the prospective associations of baseline, cumulative average, and recent psychosocial stress with the risk of incident T2D in middle-aged adults.
METHODS
We analyzed data from 7,880 participants aged 40-64 years without T2D at baseline. Psychosocial stress was assessed repeatedly using the Psychosocial Well-Being Index-Short Form. Incidence rate ratios (IRRs) and 95% confidence intervals (CIs) were estimated using modified Poisson regression models with robust error estimators.
RESULTS
A total of 437 T2D cases occurred over 47,621 person-years. While baseline stress showed a non-significant association, both cumulative and recent stress demonstrated positive associations with T2D risk. Recent stress exhibited the strongest association in both male (stress vs. healthy group: IRR, 2.23; 95% CI, 1.41 to 3.52; highest [T3] vs. lowest tertile [T1]: IRR, 1.50; 95% CI, 1.07 to 2.10) and female (stress vs. healthy group: IRR, 1.72; 95% CI, 1.11 to 2.66; T3 vs. T1: IRR, 1.73; 95% CI, 1.26 to 2.37). These associations were more pronounced among participants with abdominal obesity, showing a significant positive linear trend (Bonferroni-corrected threshold, p=0.003).
CONCLUSIONS
Recent psychosocial stress was associated with an increased incidence of T2D, underscoring the importance of integrating psychosocial factors into diabetes prevention strategies, particularly for individuals with abdominal obesity.; Summary

Korean summary
최근(진단 전 방문)의 심리사회적 스트레스는 T2D의 위험인자로 확인되었으며, 기저 스트레스와는 유의미하지 않은 관계를 보였고 누적 스트레스와는 보다 약한 연관성을 보였다. 특히, 복부 비만이 있는 대상자에서 이러한 양상이 두드러져, 이 고위험군을 중심으로 한 스트레스 관리의 필요성이 제기된다.

Key Message
Recent psychosocial stress was identified as the strongest risk factor for type 2 diabetes (T2D), showing non-significant relationship with baseline stress and weaker link for cumulative stress. Particularly, it was more pronounced among those with abdominal obesity, highlighting the importance of stress management in T2D prevention focusing on this high-risk subgroup.

Importance of younger age group and high inflammatory status in the association between periodontal disease and diabetes mellitus: results from the Korea National Health and Nutrition Examination Survey 2012-2018: Hyunmin Lee, Myung-Hee Shin; Epidemiol Health. 2024;46:e2024088. Published online November 15, 2024; DOI: https://doi.org/10.4178/epih.e2024088

13,842 View
105 Download
2 Web of Science
2 Crossref

Abstract Summary PDF

Abstract

OBJECTIVES
Although previous studies have demonstrated an association between periodontal disease (PD) and diabetes mellitus (DM), the influence of age and the mediating role of inflammation have seldom been explored. This study investigated this association while considering the modifying effects of age and inflammatory status.

METHODS

This study included 29,491 participants from the 2012-2018 Korea National Health and Nutrition Examination Survey. The community periodontal index (CPI) was assessed by trained dentists using the World Health Organization CPI probe. PD was defined as a CPI score of 3 or 4. Pre-existing and incident DM were identified based on serum glucose levels, a history of DM diagnosis, medication use, and insulin injections. Serum high-sensitivity C-reactive protein (hs-CRP) levels were utilized as an indicator of chronic inflammation.

RESULTS

PD and DM exhibited a significant association, which was more pronounced with incident DM than with pre-existing DM, particularly in individuals younger than 65 years. Among those aged 20-44 years, the odds ratio of incident DM for CPI=4 versus CPI=0 was 2.61 (95% confidence interval, 1.16 to 6.09). High hs-CRP levels (>3 mg/L) were also associated with DM, especially in individuals with PD. This association was stronger with incident DM than with pre-existing DM. A notable joint effect was observed in younger individuals and those with PD.

CONCLUSIONS

The association between PD and DM was more pronounced in younger age groups and those with higher levels of inflammation. Therefore, early interventions for PD in younger patients may be crucial for preventing DM.

Summary

Korean summary
- 치주 질환과 당뇨병 사이의 연관성은 젊은 연령과 염증 수치가 높게 나타난 대상에서 더 두드러지게 나타남 - 치주 질환과 높은 염증 수치를 동시에 가지고 있을 경우의 당뇨 오즈비는 각각의 오즈비 합보다 더 크게 나타나 시너지 효과를 보였음 - 젊은 치주 질환 환자에 대한 조기 개입은 당뇨병 예방에 중요하게 작용할 수 있음

Key Message
• The association between PD and DM was more pronounced in younger age groups and those with higher levels of in- flammation. • The odds of DM increased synergistically for those with both PD and high inflammatory status. • Therefore, early interventions for PD in younger patients may be crucial for preventing DM.

Citations

Citations to this article as recorded by

Resveratrol supplementation as a non-surgical treatment in periodontitis and related systemic conditions
Caterina Vinciguerra, Loredana Bellia, Graziamaria Corbi, Sandro Rengo, Alessandro Cannavo
Journal of Traditional and Complementary Medicine.2026; 16(3): 241. CrossRef
Synergic Elevation of Systemic Inflammation by the Coexistence of Periodontitis and Diabetes Mellitus: A Nationwide Analysis of Korean Adults
Hye-Sun Shin
Biomedicines.2025; 13(10): 2441. CrossRef

Sex-specific associations between dietary legume subtypes and type 2 diabetes in a prospective cohort study: Hye Won Woo, Sangmo Hong, Min-Ho Shin, Sang Baek Koh, Hyeon Chang Kim, Yu-Mi Kim, Mi Kyung Kim; Epidemiol Health. 2024;46:e2024083. Published online October 17, 2024; DOI: https://doi.org/10.4178/epih.e2024083

12,377 View
128 Download
1 Web of Science
1 Crossref

Abstract Summary PDF Supplementary Material

Abstract

OBJECTIVES
Dietary soy, known for its high phytoestrogen content, has been suggested to exhibit a sex-specific association with type 2 diabetes. However, evidence regarding the sex-specific associations of different legume subtypes with type 2 diabetes remains scarce. We aimed to evaluate whether habitual consumption of soy and non-soy legumes (beans and peanuts) was prospectively and sex-specifically associated with the risk of type 2 diabetes incidence, taking into considering significant sex-specific genetic factors beyond legume consumption.

METHODS

A total of 16,666 participants (96,945 person-years) were followed and 945 incident cases were observed. Cumulative intake of legume subtypes was calculated using a food frequency questionnaire administered at baseline and during the revisit surveys.

RESULTS

Non-soy legumes are inversely associated with type 2 diabetes in both men and women. Dietary soy intake, however, demonstrated a unilaterally interacting sex-specific association with type 2 diabetes risk (pinteraction for sex=0.017). Specifically, there was a significant inverse association with type 2 diabetes risk in women (incidence rate ratio, 0.66; 95% confidence interval, 0.48 to 0.80; ptrend=0.007), but no such association was observed in men. This sex-specific association persisted and even appeared antagonistic in minor allele carriers of 2 novel single nucleotide polymorphisms, rs10196939 (LRRTM4) and rs11750158 (near GFPT2) (pinteraction for sex=0.001 and 0.011, respectively).

CONCLUSIONS

Habitual consumption of legumes shows protective impacts against type 2 diabetes, although these benefits vary by sex. Non-soy legumes provide health advantages for both men and women, whereas soy consumption seems to be beneficial exclusively for women.

Summary

Korean summary
콩류 섭취는 제2형 당뇨병 예방에 도움이 되는데, 대두를 제외한 콩류와 땅콩은 남녀 모두에게 건강상의 이점이 있는 반면, 대두는 여성에게만 보호적 이점이 있는 것으로 관찰되었다. 대두 섭취는 남성과 여성에서 서로 다른 영향을 미치는 것으로 관찰되었으며, 이는 대두 섭취의 건강상의 영향이 성별에 따라 다르게 나타날 수 있음을 시사하였다.

Key Message
Our findings showed that while legume consumption was protective against type 2 diabetes, beans and peanuts demonstrated health benefits in both sexes, whereas soy's protective benefits were observed only in women. Soy consumption was observed to have different effects between men and women, suggesting that the health impact of soy intake may differ by sex.

Citations

Citations to this article as recorded by

Differential Network-Based Dietary Structure and Type 2 Diabetes Risk: A Prospective Cohort Study Using Food Co-Consumption Networks
Hye Won Woo, Yu-Mi Kim, Min-Ho Shin, Sang Baek Koh, Hyeon Chang Kim, Mi Kyung Kim
Nutrients.2026; 18(3): 506. CrossRef

Influence of practice location on prescribing, diabetes care, and colorectal cancer screening among Czech general practitioners during the COVID-19 pandemic: Jan Bělobrádek, Luděk Šídlo, Tom Philipp; Epidemiol Health. 2024;46:e2024033. Published online February 23, 2024; DOI: https://doi.org/10.4178/epih.e2024033

16,529 View
123 Download
1 Web of Science
2 Crossref

Abstract Summary PDF Supplementary Material

Abstract

OBJECTIVES
The provision of primary health care was not interrupted during the coronavirus disease 2019 (COVID-19) pandemic in Czechia, although the capacity and resources of providers changed. We examined how the pandemic affected individual general practices throughout 2017-2021, focusing on differences between urban and rural practices.

METHODS

We analysed data from the largest health insurance company in Czechia, which provides care to 4.5 million people (60% of the population). We evaluated the prescription volume, diabetes care procedures, and faecal immunochemical test (FIT) in preventive care and new pandemic-related procedures (remote consultations, testing, and vaccinations). For the spatial distribution of practices, we adapted the Organisation for Economic Cooperation and Development typology.

RESULTS

We observed minimal declines in 2020 in the rate of prescribing (-1.0%) and diabetes care (-5.1%), with a rapid resumption in 2021, but a substantial decline in FIT (-17.8% in 2020) with slow resumption. Remote consultations were used by 94% of all practices regardless of location, with testing and vaccinations more commonly performed by rural general practitioners (GPs).

CONCLUSIONS

Primary care in Czechia rose to the challenge of the COVID-19 pandemic, as shown by the finding that the volume of healthcare services provided through primary care did not decrease across most of the monitored parameters. This study also confirmed that rural GPs provide more care in-house, both in terms of prescribing and procedures performed in their practices. Future studies will need to focus on preventive care, which the pandemic has dampened in GP practices in Czechia.

Summary

Key Message
Primary care in Czechia has effectively adapted to the changes brought about by the COVID-19 pandemic. Minimal impact was observed in prescribtions and diabetic patient care. There was a significant decline in colorectal cancer screening, with a slow restitution after the pandemic subsided. Rural GPs consistently provided in-house treatment and have higher shares of both prescribing and diabetes care, as well as performing more COVID-19 specific procedures.

Citations

Citations to this article as recorded by

Geographical Disparities in Faecal Immunochemical Test‐Based Colorectal Cancer Screening Participation and Positivity Rates: A Systematic Review and Meta‐Analysis
Melkalem Mamuye Azanaw, Erin L. Symonds, Geraldine Laven‐Law, Wudneh Simegn Belay, Syme Aftab, Muktar B. Ahmed, Molla M. Wassie
Health Promotion Journal of Australia.2026;[Epub] CrossRef
Effect of Age, Practice Location and Covid-19 on the Use of POCT Methods by General Practitioners in Czechia in 2017–2021
Jan Bělobrádek, Luděk Šídlo, Tom Philipp
Acta Medica (Hradec Kralove, Czech Republic).2025; 68(3): 87. CrossRef

Impact of electronic cigarette use on the increased risk of diabetes: the Korean Community Health Survey: Wonseok Jeong, Seungju Kim; Epidemiol Health. 2024;46:e2024029. Published online February 13, 2024; DOI: https://doi.org/10.4178/epih.e2024029

20,179 View
198 Download
6 Web of Science
8 Crossref

Abstract Summary PDF

Abstract

OBJECTIVES
Only a few studies have solely investigated the health impacts of electronic cigarettes on diabetes while considering the impact of conventional cigarettes. Therefore, this study aimed to examine the effect of electronic cigarette smoking on diabetes in Korean dual smokers, electronic cigarette smokers, conventional cigarette smokers, and non-smokers.

METHODS

Data were obtained from the 2021 and 2022 Korean Community Health Surveys of 460,603 Korean adults. The main independent variable was smoking behavior. Participants were categorized according to their smoking behavior, as dual smokers, electronic cigarette smokers, conventional cigarette smokers, and non-smokers. The dependent variable, the presence of diabetes, was defined by a doctor’s diagnosis. Multiple logistic regression analysis was performed to examine the association between smoking behavior and diabetes. Subgroup analyses were also performed to investigate the associations among different socioeconomic groups.

RESULTS

Conventional cigarette smokers had a higher risk of diabetes than did non-smokers (adjusted odds ratio [aOR], 1.22; 95% confidence interval [CI], 1.19 to 1.26). More importantly, those who only vaped electronic cigarettes were at high risk of diabetes (aOR, 1.15; 95% CI, 1.01 to 1.31). Lastly, dual smokers had the highest aOR for diabetes among other smoking behavior groups (aOR, 1.39; 95% CI, 1.22 to 1.58). Dual smoking was associated with the highest risk of diabetes in most subgroups.

CONCLUSIONS

This study suggests that conventional cigarette use and smoking electronic cigarettes negatively impact diabetes, and using both types leads to worse health outcomes. Therefore, cessation of all types of smoking is necessary for a healthy life.

Summary

Korean summary
이 연구는 한국의 이중 흡연자, 전자담배 흡연자, 일반 담배 흡연자 및 비흡연자들 사이에서 전자담배가 당뇨병에 미치는 영향을 조사하였다. 데이터는 460,603명의 한국 성인을 대상으로 한 2021년과 2022년 한국 지역사회 건강 조사를 사용하였다. 우리는 일반 담배나 전자담배 사용이 당뇨병에 부정적인 영향을 미친다는 것을 발견했으며, 두 가지를 함께 사용하면 건강 상태가 더욱 악화될 수 있다. 이에, 건강한 삶을 유지하기 위해서는 모든 형태의 흡연을 중단하는 것이 필수적이다.

Key Message
This study investigated how smoking electronic cigarettes affects diabetes among Korean dual smokers, electronic cigarette smokers, conventional cigarette smokers, and non-smokers. Data were obtained from the 2021 and 2022 Korean Community Health Surveys of 460,603 Korean adults. We found that using traditional cigarettes or electronic cigarettes adversely affects diabetes, and the combined use of both can lead to worse health outcomes. Therefore, quitting all forms of smoking is essential for maintaining a healthy life.

Citations

Citations to this article as recorded by

Molecular Health Effects of Electronic Cigarettes
Paweł Sutkowy, Igor Hadryś, Wiktor Gmys, Przemysław Grzempa, Aleksandra Sobieszczańska, Weronika Tuska, Karolina Błachnio, Alina Woźniak
Biomolecules.2026; 16(2): 264. CrossRef
Associations Between Tobacco Use Behaviors and Metabolic Syndrome in Korean Adults: Analysis of the 2020–2022 KNHANES
Jinsun Kim, Seungju Kim
Journal of Preventive Medicine and Public Health.2026; 59(2): 174. CrossRef
Association of Heated Tobacco Product Use With Risk of Type 2 Diabetes
Huan Hu, Tohru Nakagawa, Toru Honda, Shuichiro Yamamoto, Maki Konishi, Tetsuya Mizoue
American Journal of Preventive Medicine.2026; 71(3): 108368. CrossRef
Association Between Electronic Cigarette Use and Risk of Obstructive Sleep Apnea Among Korean Adults: A Cross-Sectional Nationwide Population-Based Study
Wonseok Jeong, Min Ji Song, Ji Hye Shin, Ji Hyun Kim
Journal of Clinical Medicine.2025; 14(11): 3616. CrossRef
Tobacco, electronic cigarette, alcohol and cannabis use among individuals diagnosed with diabetes. A national survey in France
Ivan Berlin, Romain Guignard, Sandrine Fosse-Edorh, Guillemette Quatremère, Emmanuel Lahaie, Viêt Nguyen-Thanh
Primary Care Diabetes.2025; 19(5): 478. CrossRef
New nicotine and tobacco products and risk of major diseases: A review of the scientific evidence
Sofia Carlsson, Miranda Beck, Anna Bergström, Kristian Dreij, Koustav Ganguly, Maria Kippler, Federica Laguzzi, Karin Leander, Donghau Lu, Lena Palmberg, Swapna Upadhyay, Anna Zettergren, Göran Pershagen
Scandinavian Journal of Public Health.2025;[Epub] CrossRef
Differential associations between smoking, e-cigarette use, and diabetes prevalence
Yusuff Adebayo Adebisi, Chimwemwe Ngoma, Davide Campagna, Antonio Ceriello, Najim Z. Alshahrani, Anoop Misra, Abdul Basit, Cristina Russo, Tadej Battelino, Noel Somasundaram, Muhammad Yazid Jalaludin, Phuong Le Dinh, Yoshifumi Saisho, Magdalena Walicka, V
Diabetes & Metabolic Syndrome: Clinical Research & Reviews.2025; 19(10): 103331. CrossRef
Investigating Pre-pregnancy and Late-Pregnancy E-cigarette Use Exposure and Gestational Diabetes Mellitus
Elizabeth R Burgess, Hope M Cherian, Carter Wegner, Grettel Castro, Marcia Varella
Cureus.2025;[Epub] CrossRef

Associations of the magnesium depletion score and magnesium intake with diabetes among US adults: an analysis of the National Health and Nutrition Examination Survey 2011-2018: Zhong Tian, Shifang Qu, Yana Chen, Jiaxin Fang, Xingxu Song, Kai He, Kexin Jiang, Xiaoyue Sun, Jianyang Shi, Yuchun Tao, Lina Jin; Epidemiol Health. 2024;46:e2024020. Published online January 10, 2024; DOI: https://doi.org/10.4178/epih.e2024020

37,991 View
206 Download
16 Web of Science
16 Crossref

Abstract Summary PDF Supplementary Material

Abstract

OBJECTIVES
The magnesium depletion score (MDS) is considered more reliable than traditional approaches for predicting magnesium deficiency in humans. We explored the associations of MDS and dietary magnesium intake with diabetes.

METHODS

We obtained data from 18,853 participants in the National Health and Nutrition Examination Survey 2011-2018. Using multivariate regression and stratified analysis, we investigated the relationships of both MDS and magnesium intake with diabetes. To compute prevalence ratios (PRs), we employed modified Poisson or log-binomial regression. We characterized the non-linear association between magnesium intake and diabetes using restricted cubic spline analysis.

RESULTS

Participants with MDS ≥2 exhibited a PR of 1.26 (95% confidence interval [CI], 1.19 to 1.34) for diabetes. Per-standard deviation (SD) increase in dietary magnesium intake was associated with a lower prevalence of diabetes (PR, 0.91; 95% CI, 0.87 to 0.96). Subgroup analyses revealed a positive association between MDS ≥2 and diabetes across all levels of dietary magnesium intake, including the lowest (PR, 1.35; 95% CI, 1.18 to 1.55), middle (PR, 1.23; 95% CI, 1.12 to 1.35), and highest tertiles (PR, 1.25; 95% CI, 1.13 to 1.37; pinteraction<0.001). Per-SD increase in magnesium intake was associated with lower diabetes prevalence in participants with MDS <2 (PR, 0.92; 95% CI, 0.87 to 0.98) and those with MDS ≥2 (PR, 0.91; 95% CI, 0.84 to 0.98; pinteraction=0.030).

CONCLUSIONS

MDS is associated with diabetes, particularly among individuals with low magnesium intake. Adequate dietary magnesium intake may reduce diabetes risk, especially in those with high MDS.

Summary

Key Message
The relationship between magnesium intake and risk is currently understudied in the field of diabetes prevention. The study found that magnesium deficiency is associated with diabetes risk, especially in people with low magnesium intake. Dietary magnesium supplementation may reduce risk and provide a new strategy for diabetes prevention. This study fills this knowledge gap and is important for scientific understanding of diabetes pathogenesis and epidemiological prevention and control.

Citations

Citations to this article as recorded by

Chronic Latent Magnesium Deficiency and an Unbalanced Calcium-to-Magnesium Ratio Impact Fetal Development and Maternal Health
Deanna J. Nelson, Laura J. Sommerville
Journal of Dietary Supplements.2026; 23(2): 268. CrossRef
Magnesium depletion score is associated with arterial stiffness: data from the Brisighella Heart Study
Federica Fogacci, Marina Giovannini, Elisa Grandi, Sergio D’Addato, Claudio Borghi, Arrigo F.G. Cicero
Journal of Hypertension.2026; 44(5): 771. CrossRef
Magnesium Depletion Score and Mortality in Individuals with Metabolic Dysfunction Associated Steatotic Liver Disease over a Median Follow-Up of 26 Years
Lei Fan, Xiangzhu Zhu, Xinyuan Zhang, Shakirat Salvador, Xuehong Zhang, Martha J. Shrubsole, Manhal J. Izzy, Qi Dai
Nutrients.2025; 17(2): 244. CrossRef
Higher magnesium depletion score increases the risk of all‑cause and cardiovascular mortality in US adults with diabetes
Hao Zhang, Liping Kuang, Qiang Wan, Amirmohammad Khalaji
PLOS ONE.2025; 20(1): e0314298. CrossRef
Association of magnesium depletion score with all-cause and cardiovascular mortality in hyperlipidemia adults: a large nationwide population-based study
Chengxing Liu, Yuntao Feng, Fan Ping, Litang Huang, Jun Qian, Li Zhou, Fei Chen, Xuebo Liu
Journal of Health, Population and Nutrition.2025;[Epub] CrossRef
Hypomagnesemia: exploring its multifaceted health impacts and associations with blood pressure regulation and metabolic syndrome
Wenlong Wu, Ming Gong, Pan Liu, Huiying Yu, Xue Gao, Xin Zhao
Diabetology & Metabolic Syndrome.2025;[Epub] CrossRef
Magnesium depletion score is a risk factor for all-cause, cancer and cardiovascular disease mortality in cancer survivors: evidence from two prospective cohort studies
Yunmiao Ma, Minjie Li, Xing Liu
Frontiers in Nutrition.2025;[Epub] CrossRef
Association between magnesium depletion score and overactive bladder among U.S. Adults using data from NHANES 2005–2018
Hege Bian, Yuzhong Zhang, Kun Liu
Scientific Reports.2025;[Epub] CrossRef
Association between magnesium depletion score and atherosclerotic cardiovascular disease: Findings from NHANES 2005 to 2018
Tianjiao Liu, Jie Wang, Chenghuan Ren, Ruotong Yu, Changgeng Fu
Medicine.2025; 104(33): e43914. CrossRef
Magnesium Depletion Score as an Indicator of Health Risk and Nutritional Status—A Scoping Review
Rebecca Costello, Zhongqi Fan, Taylor Wallace
Nutrients.2025; 17(20): 3286. CrossRef
Blood glucose control, magnesium status, and diabetic retinopathy in patients with type 2 diabetes mellitus: Evidence from NHANES 2005–2018
Liping Gu, Song Jia, Juan Chen
Science Progress.2025;[Epub] CrossRef
Magnesium depletion score and stroke in US adults: Analysis of NHANES 1999 to 2018
Li-Chao Zhang, Zhi-Qiang Ye, Wen-Liang Shuai, Chen-Qi He, Xu-Ying Yu, Li-Min Zhuang, Li-Min Gong
Medicine.2025; 104(51): e46376. CrossRef
Magnesium Matters: A Comprehensive Review of Its Vital Role in Health and Diseases
Ghizal Fatima, Andrej Dzupina, Hekmat B Alhmadi, Aminat Magomedova, Zainab Siddiqui, Ammar Mehdi, Najah Hadi
Cureus.2024;[Epub] CrossRef
Magnesium depletion score and depression: a positive correlation among US adults
Wei Zhao, Hai Jin
Frontiers in Public Health.2024;[Epub] CrossRef
Magnesium depletion score and gout: insights from NHANES data
Xu Cao, Haixia Feng, Huijie Wang
Frontiers in Nutrition.2024;[Epub] CrossRef
Association between magnesium depletion score and the prevalence of kidney stones in the low primary income ratio: a cross-sectional study of NHANES 2007–2018
Jiahao Wang, Yunfei Xiao, Yaqing Yang, Shan Yin, Jianwei Cui, Ke Huang, Jia Wang, Yunjin Bai
International Journal of Surgery.2024; 110(12): 7636. CrossRef

A prospective association between dietary mushroom intake and the risk of type 2 diabetes: the Korean Genome and Epidemiology Study–Cardiovascular Disease Association Study: Yu-Mi Kim, Hye Won Woo, Min-Ho Shin, Sang Baek Koh, Hyeon Chang Kim, Mi Kyung Kim; Epidemiol Health. 2024;46:e2024017. Published online January 8, 2024; DOI: https://doi.org/10.4178/epih.e2024017

19,833 View
156 Download
3 Web of Science
3 Crossref

Abstract Summary PDF Supplementary Material

Abstract

OBJECTIVES
Mushrooms, known for their nutritious and functional components, are considered healthy and medicinal. This study investigated the prospective association between dietary mushroom consumption and the incidence of type 2 diabetes among Korean adults aged ≥40 years.

METHODS

In total, 16,666 participants who were not taking anti-diabetic medication or insulin and had normal fasting blood glucose (FBG; <126 mg/dL) were included. We used the cumulative average dietary consumption of mushrooms as an exposure metric, calculated from food frequency questionnaires at every follow-up, along with covariates collected during a baseline survey. To estimate incidence rate ratios (IRRs) for type 2 diabetes, a modified Poisson regression model with a robust error estimator was applied.

RESULTS

In multivariable models, dietary mushroom consumption was inversely associated with type 2 diabetes incidence in both genders (men: IRR, 0.65; 95% confidence interval [CI], 0.47 to 0.90; plinearity=0.043 in the highest quartile (Q4) vs. the lowest quartile (Q1); women: IRR, 0.70; 95% CI, 0.54 to 0.93; plinearity=0.114 in Q4 vs. Q1). The inverse association remained after adjustment for dietary factors instead of dietary quality index, the baseline FBG, and the exclusion of incidence within the first year. Additionally, no significant interaction was found regarding the risk of type 2 diabetes between dietary mushroom consumption and participants’ gender or other factors.

CONCLUSIONS

Dietary mushroom consumption was inversely linked with the risk of type 2 diabetes incidence in both genders, indicating the beneficial role of mushrooms in preventing the disease.

Summary

Korean summary
- 흔히 사용하는 버섯의 식이 섭취량이 증가함에 따라 한국 40세 이상 성인에서 제2형 당뇨병 발생 위험이 낮았다. - 이러한 역관계는 성별과 다양한 식이 배경에서도 일관성을 유지하였고, 이는 버섯이 제2형 당뇨병 예방에 있어 잠재적인 식이요소로서의 가능성을 보여주는성을 보여주는 보여주는 결과이다.

Key Message
• Increased dietary consumption of commonly used mushrooms is associated with a lower risk of type 2 diabetes incidence among adults aged 40 years or older in Korea. • This inverse relationship remains consistent across genders and various dietary backgrounds, underscoring the potential of mushrooms as a preventive dietary component against.

Citations

Citations to this article as recorded by

Underappreciated Health Benefits of Edible Mushrooms in the Dietary Management of Chronic Kidney Disease
Mona S. Calvo, Jaime Uribarri
Journal of Renal Nutrition.2026; 36(2): 187. CrossRef
Integrative Roles of Functional Foods, Microbiotics, Nutrigenetics, and Nutrigenomics in Managing Type 2 Diabetes and Obesity
Hong Nhung Lam, Shih-Ping Lin, Dang Hien Ngan Nguyen, Chiao-Ming Chen, Chien-Tien Su, Te-Chao Fang, Sing-Chung Li
Nutrients.2025; 17(4): 608. CrossRef
Protective Properties of the White Button Mushroom, Agaricus bisporus, in a Mouse Model of Colitis
Elaine Dempsey, Aaron M. Walsh, Supriya Yadav, Jude Wilson, Frederick J. Sheedy, Sinead C. Corr
Molecular Nutrition & Food Research.2025;[Epub] CrossRef

Brief Communication

Association between cardiac arrhythmia before pregnancy and gestational diabetes: a nationwide population-based study in Korea: You-Jung Choi, Won Young Wi, Geum Joon Cho, Jin Oh Na; Epidemiol Health. 2023;45:e2023103. Published online December 4, 2023; DOI: https://doi.org/10.4178/epih.e2023103

13,206 View
207 Download

Abstract Summary PDF Supplementary Material: Abstract
Given the higher prevalence of cardiac arrhythmias in individuals with diabetes, we investigated the relationship between cardiac arrhythmias and the incidence of gestational diabetes (GDM). This retrospective cohort study utilized data from the Korean Health Insurance Service database, encompassing 1,113,729 women who gave birth between January 2007 and December 2015. After excluding those who did not undergo National Health Screening tests within 1 year prior to pregnancy, those with multifetal pregnancies, and those diagnosed with diabetes, we analyzed 365,880 singleton pregnancies without a history of diabetes. Of these, 3,253 (0.9%) had cardiac arrhythmias, including premature extra beats, supraventricular tachyarrhythmias, and/or atrial flutter/fibrillation. GDM occurred in 31,938 (8.7%) subjects during pregnancy, and was more prevalent in women with cardiac arrhythmia than in those without (14.9 vs. 8.7%, p<0.001). In the multivariate analysis, the association between cardiac arrhythmia and GDM remained statistically significant (adjusted odds ratio, 1.78; 95% confidence interval, 1.61 to 1.97; p<0.001). Subgroup analysis revealed that the risk of GDM was consistently statistically significant in subjects with cardiac arrhythmia, regardless of age, body mass index, and the presence or absence of chronic hypertension. Therefore, cardiac arrhythmias before and during pregnancy appear to be associated with an increased risk of developing GDM.; Summary

Korean summary
본 연구에서는 부정맥과 임신성 당뇨병의 발생과의 관계를 확인인하기 위하여 2007년부터 2015년까지 국민건강보험 공단 데이터를 이용하여 분만력을 가진 1,113,729명의 여성을 대상으로 진행되었습니다. 최종 분석은 과거 당뇨병 진단병력을 가지고 있는 환자를 제외하고 365,880건의 단태아 임산부를 포함하였고, 전체 대상자 중 31,938 (8.7%)에서 임신성 당뇨병을 확인하였습니다. 그 중 부정맥 병력이 확인되지 않은 임산부와 비교하였을 때, 부정맥 병력이 있는 경우 임신 기간 중 임신성 당뇨병 발생률이 높았으며 (8.7% vs. 14.9%, p<0.001), 다변량 분석에서도 부정맥과 임신 당뇨병 간의 연관성이 통계적으로 유의미하게 나타났습니다 (adjusted odds ratio, 1.78; 95% confidence interval, 1.61 to 1.97; p<0.001). 따라서, 본 연구는 임신 전후의 부정맥 병력은 임신성 당뇨병 발병 위험 증가와 관련 있음을 시사합니다.

Key Message
This nationwide population-based cross-sectional study using the Korean Health Insurance Service database showed that women with a history of cardiac arrhythmia had an elevated risk of incident GDM during pregnancy. The prevalence of GDM was significantly higher in women with cardiac arrhythmias (8.7% vs. 14.9%). There was a statistically significant association between cardiac arrhythmia and GDM (adjusted odds ratio: 1.78), suggesting that cardiac arrhythmias before and during pregnancy are linked to an increased risk of developing GDM, independent of age, BMI, and chronic hypertension.

Original Articles

Increased risk of cancer and cancer-related mortality in middle-aged Korean women with prediabetes and diabetes: a population-based study: Thi Xuan Mai Tran, Soyeoun Kim, Huiyeon Song, Boyoung Park; Epidemiol Health. 2023;45:e2023080. Published online August 28, 2023; DOI: https://doi.org/10.4178/epih.e2023080

16,393 View
99 Download
3 Web of Science
4 Crossref

Abstract Summary PDF Supplementary Material

Abstract

OBJECTIVES
This study investigated the risk of developing and dying from all types of cancer, as well as cancer-specific mortality, in women diagnosed with prediabetes and diabetes.

METHODS

We included women aged ≥40 years who underwent cancer screening from 2009 to 2014 with follow-up until 2020. Diabetes status was determined based on fasting plasma glucose levels, self-reported history of diabetes, and the use of antidiabetic medication. We quantified the risk of cancer and mortality in the prediabetes and diabetes groups, relative to the normoglycemia group, by calculating adjusted hazard ratios (aHRs).

RESULTS

The study included 8,309,393 participants with a mean age of 52.7±9.7 years. Among these participants, 522,894 cases of cancer and 193,283 deaths were detected. An increased risk of cancer was observed in both the prediabetes group (aHR, 1.03; 95% confidence interval [CI], 1.02 to 1.04) and the diabetes group (aHR, 1.13; 95% CI, 1.12 to 1.14). The highest risk was identified in those with diabetes who developed liver (aHR, 1.72; 95% CI, 1.66 to 1.79), pancreatic (aHR, 1.68; 95% CI, 1.60 to 1.76), and gallbladder cancer (aHR, 1.43; 95% CI, 1.36 to 1.51). Women with prediabetes and diabetes exhibited a 1.07-fold (95% CI, 1.05 to 1.08) and 1.38-fold (95% CI, 1.36 to 1.41) increased risk of death from cancer, respectively.

CONCLUSIONS

Both prediabetes and diabetes were associated with an elevated risk of cancer, as well as an increased risk of death from cancer, in middle-aged Korean women. However, the degree of risk varied depending on the specific site of the cancer.

Summary

Korean summary
40세 이상의 중년 여성에서 당뇨 또는 당뇨 전 단계는 암 발생 위험과 암으로 인한 사망위험을 증가시킴. 암 종별로는 위암, 대장암, 직장암, 간암, 담낭암, 췌장암, 유방암, 자궁경부암, 자궁암, 신장암, 방광암의 발생 위험이 증가한 반면, 갑상선암의 발생 위험은 감소하였음. 거의 대부분의 암종에서 당뇨는 암으로 인한 사망위험을 증가시킴

Key Message
Both prediabetes and diabetes were independently associated with an overall increased risk of cancer, with a stronger association with malignancies in the liver and pancreas in women. Additionally, both prediabetes and diabetes status are associated with an elevated risk of death from cancer. These findings support the need for prevention and management to reduce cancer-related burden and premature deaths due to cancer, not only in individuals with diabetes but also in those with prediabetes.

Citations

Citations to this article as recorded by

Overview of the prevalence and features of oncological diseases in type 2 diabetes and possible immunological mechanisms
Ya. V. Dvoryanchikov, S. M. Deunezhewa, I. A. Yatskov, V. A. Beloglazov
Problems of Endocrinology.2025; 71(2): 75. CrossRef
Prognostic value of preoperative serum tumor markers in gallbladder cancer
Qianhui Duan, Jie Zhong, Yinghui Song, Sicheng Zhang, Weimin Yi, Chuang Peng, Sulai Liu, Jianping Wu, Lianhong Zou
BMC Gastroenterology.2025;[Epub] CrossRef
A burden of proof study of the effects of exposure to high fasting plasma glucose on the risk of seven types of cancer
Paula Portal Teixeira, Yvonne Yiru Xu, Aleksandr Aravkin, Peng Zheng, Lisa M. Force, Jonathan Kocarnik, Susan McLaughlin, Theo Vos, Hailey Lenox, Simon I. Hay, Bruce Bartholow Duncan, Verônica Colpani, Chris Murray, Fernando Gerchman, Kanyin Liane Ong
Scientific Reports.2025;[Epub] CrossRef
Prediabetes persistence or remission and subsequent risk of gallbladder cancer: A nationwide cohort study
Joo-Hyun Park, Jung Yong Hong, Kyungdo Han, Young Suk Park, Joon Oh Park, Ho Yeong Lim, Jay J. Shen
European Journal of Cancer.2024; 213: 114312. CrossRef

Associations between adverse childhood experiences and diabetes among middle-aged and older Chinese: a social-ecological perspective: Siyu Zhu, Leying Hou, Jiaying Ma, Shuting Li, Weidi Sun, Wen Liu, Jiajun Hao, Wenhan Xiao, Siqing Cheng, Dexing Zhang, Dong Zhao, Peige Song; Epidemiol Health. 2023;45:e2023071. Published online August 2, 2023; DOI: https://doi.org/10.4178/epih.e2023071

16,291 View
156 Download
2 Web of Science
2 Crossref

Abstract Summary PDF Supplementary Material

Abstract

OBJECTIVES
This study examined the associations between adverse childhood experiences (ACEs) and diabetes within a social-ecological framework, incorporating personal and environmental unfavorable conditions during childhood from family, school, and community contexts.

METHODS

Data were obtained from the China Health and Retirement Longitudinal Study (2014 life history survey and 2015 survey), including 9,179 participants aged ≥45 years. ACEs were collected through self-report questionnaires, and participants were categorized based on the number of distinct ACEs experienced (0, 1, 2, 3, or ≥4 ACEs). Diabetes was defined by biomarkers, self-reported diagnosis, and treatment status. Logistic regression was conducted to explore the associations between ACEs and diabetes. Subgroup analyses were conducted by gender, age, and obesity status.

RESULTS

Compared with participants without ACEs, those exposed to any ACE (odds ratio [OR], 1.19; 95% confidence interval [CI], 1.01 to 1.40), 3 ACEs (OR, 1.32; 95% CI, 1.07 to 1.62) and ≥4 ACEs (OR, 1.29; 95% CI, 1.07 to 1.56) had an increased risk of diabetes. For each additional ACE, the risk of diabetes increased by about 5%. Regarding the source of ACEs, those originating from the family (OR, 1.23; 95% CI, 1.08 to 1.41) were associated with diabetes. In terms of specific ACE types, family members with substance abuse (OR, 1.23; 95% CI, 1.01 to 1.52), emotional abuse (OR, 1.28; 95% CI, 1.12 to 1.46), and poor parental relationship (OR, 1.25; 95% CI, 1.09 to 1.43) were associated with diabetes.

CONCLUSIONS

ACEs, particularly those originating from the family, were associated with diabetes. Interventions aimed at preventing and mitigating ACEs are essential for the early prevention of diabetes.

Summary

Key Message
From a social-ecological perspective, this study delineates an association between adverse childhood experiences (ACEs), particularly those originating from the family, and diabetes among middle-aged and older Chinese. Interventions aimed at preventing and mitigating ACEs are essential for the early prevention of diabetes.

Citations

Citations to this article as recorded by

Association of Adverse Childhood Experiences and Metabolic Syndrome: A Systematic Review and Meta‐Analysis
Joohan Kim, Luyu Xie, Alejandra Fernandez, Jaime P. Almandoz, Sarah E. Messiah
Obesity Reviews.2026;[Epub] CrossRef
Health effects associated with exposure of children to physical violence, psychological violence and neglect: a Burden of Proof study
Luisa S. Flor, Caroline Stein, Gabriela F. Gil, Mariam Khalil, Molly Herbert, Aleksandr Y. Aravkin, Alejandra Arrieta, María Jose Baeza de Robba, Flavia Bustreo, Jack Cagney, Renzo J. C. Calderon-Anyosa, Sinclair Carr, Jaidev Kaur Chandan, Joht Singh Chan
Nature Human Behaviour.2025; 9(6): 1217. CrossRef

Effects of multigrain rice and white rice on periodontitis: an analysis using data from the Korea National Health and Nutrition Examination Survey 2012-2015: Seung-Hee Ryu, Zi-lan Wang, Seon-Jip Kim, Hyun-Jae Cho; Epidemiol Health. 2023;45:e2023063. Published online July 3, 2023; DOI: https://doi.org/10.4178/epih.e2023063

20,808 View
159 Download
3 Web of Science
3 Crossref

Abstract Summary PDF

Abstract

OBJECTIVES
Numerous studies have investigated the efficacy of whole grains; however, research on multigrain remains limited. Grains exhibit combined positive effects against various diseases. The purpose of this study was to examine the impact of multigrain and white rice consumption on periodontitis.

METHODS

We analyzed data from the Korea National Health and Nutrition Examination Survey V-3 and VI, collected between 2012 and 2015, which included 12,450 patients (4,859 male and 7,591 female) aged 19-64 years. The World Health Organization’s Community Periodontal Index (CPI) was utilized to assess the presence of periodontitis, with periodontitis defined as a CPI index score of ≥3. Multivariable logistic regression analysis was performed after adjusting for potential confounding variables.

RESULTS

The group that consumed only multigrain rice was less likely to have periodontitis than the group that consumed only white rice (odds ratio [OR], 0.80; 95% confidence interval [CI], 0.69 to 0.93). When stratified by sex, the risk of periodontitis demonstrated a 24% decrease in female who consumed only multigrain rice (OR, 0.76; 95% CI, 0.62 to 0.93). A similar result was observed in the age group of 40-64 years (OR, 0.84; 95% CI, 0.71 to 0.99). In the diabetes stratification model, the normal group that consumed only multigrain rice exhibited a 25% decrease in the odds of periodontitis (OR, 0.75; 95% CI, 0.62 to 0.91).

CONCLUSIONS

Our findings suggest that the prevalence of periodontitis may vary depending on the type of rice consumed.

Summary

Korean summary
본 연구에서는 우리나라의 대규모 자료를 이용하여 쌀 섭취 종류가 치주염 위험에 미치는 영향을 살펴보았다. 우리의 연구 결과는 잡곡밥을 매일 2회 이상 섭취하는 것이 흰쌀밥을 먹는 것보다 치주염 예방에 더 효과적이라는 것을 보여준다. 이러한 결과는 당뇨병이 있는 사람에 비해 건강한 사람, 남성보다는 여성, 40~64세에서 더 큰 예방 효과를 시사한다.

Key Message
In this study, we examined the impact of different types of rice consumption on the risk of periodontitis using large-scale data from Korea. The group that consumed only multigrain rice was less likely to have periodontitis than the group that consumed only white rice (odds ratio [OR]=0.80; 95% confidence interval [CI], 0.69–0.93). The risk of periodontitis was reduced by 24% in female who consumed only multigrain rice, 16% decrease in the 40–64 age group, and in the diabetic stratification model, the normal group who consumed only multigrain rice had a 25% decrease in periodontitis risk.

Citations

Citations to this article as recorded by

Is Starch Intake Associated With Periodontal Status? An 11‐Year Longitudinal Analysis Among Finnish Adults
F. H. Jangda, A. L. Suominen, A. Lundqvist, S. Männistö, A. Golkari, E. Bernabé
Journal of Clinical Periodontology.2025; 52(3): 353. CrossRef
The need and strategies for increasing whole-grain intake: a narrative review focused on the UK and Ireland
Neil Bernard Boyle, Louise Dye, Chris J. Seal
British Journal of Nutrition.2025; 134(7): 600. CrossRef
Trends and Characteristics of Brown Rice Consumption among Adults in Japan: An Analysis of the National Health and Nutrition Surveys, 2012–2019
Nayu Ikeda, Miwa Yamaguchi, Nobuo Nishi
Nutrients.2024; 16(10): 1473. CrossRef

Clinical traits and systemic risks of familial diabetes mellitus according to age of onset and quantity: an analysis of data from the community-based KoGES cohort study: Ju-Yeun Lee, Kyungsik Kim, Sangjun Lee, Woo Ju An, Sue K. Park; Epidemiol Health. 2023;45:e2023029. Published online February 23, 2023; DOI: https://doi.org/10.4178/epih.e2023029

18,466 View
244 Download
1 Web of Science
1 Crossref

Abstract Summary PDF Supplementary Material

Abstract

OBJECTIVES
The aim of this study was to clarify the clinical trait of familial diabetes mellitus (DM) by analyzing participants’ risk of DM according to the age of DM onset in parents and siblings, and to evaluate individuals’ risk of DM-associated cardiometabolic diseases.

METHODS

Altogether, 211,173 participants aged ≥40 years from the Korean Genome and Epidemiology Study were included in this study. The participants were divided into groups based on the number (1 or 2 relatives) and age of onset (no DM and early, common, or late onset) of familial DM. Participants’ risk of DM was assessed using a Cox regression model with hazard ratios and 95% confidence intervals (CIs). A logistic regression model with odds ratios was used to evaluate associations among the participants’ likelihood of acquiring cardiometabolic diseases such as hypertension, chronic kidney disease (CKD), and cardiovascular disease.

RESULTS

The risk of developing DM was 2.02-fold (95% CI, 1.88 to 2.18) and 2.88-fold (95% CI, 2.50 to 3.33) higher, respectively, in participants with 1 and 2 family members diagnosed with familial DM. It was 2.72-fold (95% CI, 2.03 to 3.66) higher in those with early-onset familial DM. In the early-onset group, the respective risks of hypertension and CKD were 1.87-fold (95% CI, 1.37 to 2.55) and 4.31-fold (95% CI, 2.55 to 7.27) higher than in the control group.

CONCLUSIONS

The risk of DM and related cardiometabolic diseases was positively associated with the number of family members diagnosed with DM and an early diagnosis in family members with DM.

Summary

Korean summary
본 연구는 한국인유전체역학조사사업 역학자료를 이용하여, 당뇨병을 진단받은 가족 구성원 (부모 및 형제)의 수가 많고 당뇨병이 조기에 발생할수록 개인의 당뇨발생 위험도가 높아짐을 보고하였습니다. 또한 당뇨병이 조기에 발생한 가족구성원이 있을 경우 개인의 일부 심대사질환과의 연관성이 있을 수 있음을 설명하였습니다.

Key Message
This study demonstrated that the risk of diabetes in individuals was significantly associated with the quantity and the onset of family members diagnosed with diabetes. We also explained that having a family member with early-onset diabetes can be associated with some cardiometabolic diseases in individuals.

Citations

Citations to this article as recorded by

Assessing blood sugar measures for predicting new-onset diabetes and cardiovascular disease in community-dwelling adults
Jung-Hwan Kim, Yaeji Lee, Chung-Mo Nam, Yu-Jin Kwon, Ji-Won Lee
Endocrine.2024; 86(2): 528. CrossRef

COVID-19: Health Statistics

Changes in the management of hypertension, diabetes mellitus, and hypercholesterolemia in Korean adults before and during the COVID-19 pandemic: data from the 2010-2020 Korea National Health and Nutrition Examination Survey: Yoonjung Kim, Suyeon Park, Kyungwon Oh, Hongseok Choi, Eun Kyeong Jeong; Epidemiol Health. 2023;45:e2023014. Published online February 1, 2023; DOI: https://doi.org/10.4178/epih.e2023014

24,815 View
221 Download
10 Web of Science
11 Crossref

Abstract Summary PDF Supplementary Material

Abstract

OBJECTIVES
This study aimed to analyze the changes in chronic disease management indicators, including hypertension, diabetes mellitus, and hypercholesteremia, from 2010-2020 and before (2019) and during (2020) the coronavirus disease 2019 (COVID-19) pandemic.

METHODS

This study included 58,504 individuals aged ≥30 years who participated in the Korea National Health and Nutrition Examination Survey 2010-2020. Trends in the prevalence, awareness, treatment, and control of chronic diseases and the difference in those between before and during the COVID-19 pandemic were analyzed using the SAS program PROC SURVEYREG.

RESULTS

From 2010-2020, the awareness, treatment, and control in adults aged ≥30 years for hypertension and hypercholesterolemia continuously improved, whereas no significant change in the management indicators of diabetes mellitus was observed. The prevalence of hypertension, diabetes mellitus, and hypercholesterolemia in men increased from before to during the COVID- 19 pandemic. However, there was no significant change in the management indicators of hypertension and diabetes mellitus in men and women, and the awareness, treatment, and control rates for hypercholesterolemia increased by 5.5%p, 6.9%p, and 4.1%p respectively.

CONCLUSIONS

In 2020, the first year of the COVID-19 pandemic, the prevalence of hypertension, diabetes mellitus, and hypercholesterolemia increased, but the management indicators of the chronic diseases did not significantly deteriorate. Considering the ongoing COVID-19 pandemic, it is necessary to monitor changes in chronic disease management indicators and to develop efficient and accessible chronic disease prevention and management programs.

Summary

Korean summary
국민건강영양조사 자료를 분석한 결과 11년간(2010-2020년) 성인의 고혈압, 고콜레스테롤혈증 인지율, 치료율, 치료자 중 조절률은 개선된 반면 당뇨병은 변화가 없었다. 코로나19 유행 전(2019년)·후(2020년) 비교시 남자에서 고혈압, 당뇨병, 고콜레스테롤혈증 유병률이 증가했다. 그러나 고혈압, 당뇨병 관리지표는 변화가 없었고, 고콜레스테롤혈증 관리지표만 개선되었다.

Key Message
The rates of awareness, treatment, and control in adults aged ≥30 years for hypertension and hypercholesterolemia continuously improved, whereas no significant change in the management indicators of diabetes mellitus was observed over the past 11 years (2010-2020). The prevalence of hypertension, diabetes mellitus, and hypercholesterolemia in men increased from before (2019) to during (2020) the COVID-19 pandemic. However, there was no significant change in the management indicators of hypertension and diabetes mellitus in men and women, and that of hypercholesterolemia improved.

Citations

Citations to this article as recorded by

Plan and operations of the 10th Korea National Health and Nutrition Examination Survey (2025–2027)
Sun-Ja Kim, Sihyun Park, Sunja Kim, Suyeon Park, Yoonjung Kim, Yunjung Choi, Sungha Yun, Kyungwon Oh
Epidemiology and Health.2026; 48: e2026001. CrossRef
Korea Hypertension Fact Sheet 2025: national trends in hypertension with a special analysis of hypertensive disorders of pregnancy
Hyeon Chang Kim, Hokyou Lee, Hansol Choi, Hayan Kwon, Jaeyong Lee, Minsung Cho, Dasom Son, Sang Gyeong Lee, Na Yeon Ahn, Jeonga Park, Song Vogue Ahn, Dae Young Cheon, JoonNyung Heo, Jong Hyun Jhee, Eunji Kim, Hyeok-Hee Lee, Ju-Mi Lee, Seung Won Lee, Min-H
Clinical Hypertension.2026;[Epub] CrossRef
Korea Hypertension Fact Sheet 2024: nationwide population-based analysis with a focus on young adults
Hyeon Chang Kim, Hokyou Lee, Hyeok-Hee Lee, Song Vogue Ahn, Ju-Mi Lee, Dae Young Cheon, Jong Hyun Jhee, Minjae Yoon, Min-Ho Shin, JoonNyung Heo, Eunji Kim, Seung Won Lee, Jaeyong Lee, Yeon Woo Oh, Jooeun Jeon, Minsung Cho, Dasom Son, Na Yeon Ahn
Clinical Hypertension.2025;[Epub] CrossRef
Effect modification by cardiovascular and metabolic disease onset on long-term PM2.5 exposure and mortality: a nationwide cohort study
Hyemin Jang, Jinah Park, Eun Soo Lee, Dongmug Kang, Jeongmin Moon, Insung Song, Seoyeong Ahn, Ayoung Kim, Cinoo Kang, Jieun Oh, Dohoon Kwon, Jieun Min, Ejin Kim, Michelle L. Bell, Ho Kim, Whanhee Lee
Scientific Reports.2025;[Epub] CrossRef
Predictive Model of Medication Adherence among Hypertension and Diabetes Patients Using the Korea Health Panel Data
Seonhye Jeong, Yuyoung Lee, Moonhyang Kim, Yeoungsuk Song
Journal of Korean Public Health Nursing.2025; 39(3): 354. CrossRef
One-year post-acute COVID-19 syndrome and mortality in South Korea: a nationwide matched cohort study using claims data
Jung-Hyun Won, Yesol Hong, Siun Kim, Howard Lee
Frontiers in Public Health.2024;[Epub] CrossRef
Impact of the COVID-19 Pandemic on Obesity, Metabolic Parameters and Clinical Values in the South Korean Adult Population
Anna Kim, Eun-yeob Kim, Jaeyoung Kim
Journal of Clinical Medicine.2024; 13(10): 2814. CrossRef
Effects of the COVID-19 Pandemic on the Medical Use of Elderly Patients with Hypertension: A Nationwide Cohort Study in Korea
Eunbyul Cho, Sujeong Han, Jae-ryun Lee, Hyejin Lee, Bumjo Oh
Korean Journal of Family Medicine.2024; 45(5): 283. CrossRef
Socioeconomic inequalities in the prevalence, non-awareness, non-treatment, and non-control of diabetes among South Korean adults in 2021
Seongju Kim, Dong Jun Kim, Hooyeon Lee, Dong Keon Yon
PLOS ONE.2024; 19(11): e0313988. CrossRef
Topic Modeling-Based Analysis of News Keywords Related to Patients with Diabetes during the COVID-19 Pandemic
Jeong-Won Han, Jung Min Kim, Hanna Lee
Healthcare.2023; 11(7): 957. CrossRef
Molecular Mechanisms Responsible for Diabetogenic Effects of COVID-19 Infection—Induction of Autoimmune Dysregulation and Metabolic Disturbances
Barbara Grubišić, Luka Švitek, Klara Ormanac, Dea Sabo, Ivica Mihaljević, Ines Bilić-Ćurčić, Tea Omanović Omanović Kolarić
International Journal of Molecular Sciences.2023; 24(14): 11576. CrossRef

Original Articles

Long-term association of pericardial adipose tissue with incident diabetes and prediabetes: the Coronary Artery Risk Development in Young Adults Study: Minsuk Oh, Wonhee Cho, Dong Hoon Lee, Kara M. Whitaker, Pamela J. Schreiner, James G. Terry, Joon Young Kim; Epidemiol Health. 2023;45:e2023001. Published online December 3, 2022; DOI: https://doi.org/10.4178/epih.e2023001

12,579 View
126 Download
1 Web of Science

Abstract Summary PDF Supplementary Material: Abstract
OBJECTIVES
We examined whether pericardial adipose tissue (PAT) is predictive of prediabetes and type 2 diabetes over time.
METHODS
In total, 2,570 adults without prediabetes/diabetes from the Coronary Artery Risk Development in Young Adults Study were followed up over 15 years. PAT volume was measured by computed tomography scans, and the new onset of prediabetes/diabetes was examined 5 years, 10 years, and 15 years after the PAT measurements. Multivariable Cox regression models were used to examine the association between the tertile of PAT and incident prediabetes/diabetes up to 15 years later. The predictive ability of PAT (vs. waist circumference [WC], body mass index [BMI], waist-to-height ratio [WHtR]) for prediabetes/diabetes was examined by comparing the area under the receiver operating characteristic curve (AUC).
RESULTS
The highest tertile of PAT was associated with a 1.56 times (95% confidence interval [CI], 1.03 to 2.34) higher rate of diabetes than the lowest tertile; however, no association was found between the highest tertile of PAT and prediabetes in the fully adjusted models, including additional adjustment for BMI or WC. In the fully adjusted models, the AUCs of WC, BMI, WHtR, and PAT for predicting diabetes were not significantly different, whereas the AUC of WC for predicting prediabetes was higher than that of PAT.
CONCLUSIONS
PAT may be a significant predictor of hyperglycemia, but this association might depend on the effect of BMI or WC. Additional work is warranted to examine whether novel adiposity indicators can suggest advanced and optimal information to supplement the established diagnosis for prediabetes/diabetes.; Summary

Korean summary
본 연구는 심장 내 축적되는 내장지방과 5년에서 15년 뒤의 당뇨병 전조 단계 및 당뇨병의 발생률과 연관성이 있음을 제안한다. 또한, 본 연구는 심장 내 내장지방과 당뇨병 발생률의 관계는 체질량 지수 또는 허리둘레의 영향에 따라 상이할 수 있음을 제안한다.

Key Message
Pericardial adipose tissue may be a significant predictor of future hyperglycemia in adults, but this association might depend on the effect of body mass index or waist circumference.

Type 2 diabetes mellitus increases the severity of non-fatal injuries, but not the risk of fatal injuries, among driver victims of motor vehicle crashes in Taiwan: I-Lin Hsu, Wen-Hsuan Hou, Ya-Hui Chang, Chung-Yi Li; Epidemiol Health. 2022;44:e2022076. Published online September 16, 2022; DOI: https://doi.org/10.4178/epih.e2022076

16,658 View
139 Download
2 Web of Science
2 Crossref

Abstract Summary PDF Supplementary Material

Abstract

OBJECTIVES
Limited information is available on whether diabetes increases the severity of injuries from motor vehicle crashes (MVCs). This study aimed to investigate the association of type 2 diabetes with injury severity among driver victims of MVCs.

METHODS

This cohort study involved 75,737 adult driver victims with type 2 diabetes from Taiwan’s Police-Reported Traffic Accident Registry in 2015-2017, along with 150,911 sex-, age-, and calendar year-matched controls. The severity level of non- fatal injuries was derived from the International Classification of Diseases Programs for Injury Categorization based on the diagnostic codes of National Health Insurance claims within 3 days after an MVC. Information on fatal injuries within 3 days after an MVC was obtained from the Taiwan Death Registry. Logistic regression models were used to estimate the odds ratios (ORs) and the corresponding 95% confidence intervals (CIs) of injury severity in association with type 2 diabetes.

RESULTS

After adjusting for potential confounders, driver victims with type 2 diabetes experienced significantly higher risks of mild and severe non-fatal injuries than their counterparts without diabetes, with covariate-adjusted ORs of 1.08 (95% CI, 1.05 to 1.11) and 1.28 (95% CI, 1.20 to 1.37), respectively. By contrast, the adjusted OR for fatal injuries was not significantly elevated, at 1.02 (95% CI, 0.89 to 1.18). Similar results were found when car and scooter driver victims were analyzed separately.

CONCLUSIONS

Type 2 diabetes was found to moderately increase the severity of non-fatal injuries from MVCs among car and scooter driver victims.

Summary

Key Message
With 75,737 driver victims with diabetes and 150,911 matched controls, this study showed an 8% and 28% increase in mild and severe non-fatal injury, respectively among driver victims with diabetes. Such increase in risk was equally applied to both car and scooter drivers. No increase in risk of 3-day mortality after crash was found.

Citations

Citations to this article as recorded by

Prevalence of diabetes mellitus among traumatic patients admitted to Aseer Central Hospital, Aseer Region, Abha, Saudi Arabia: cross-sectional study
Majed Mohammed Al Saleh, Bandar A. Alasmari, Ali Mohammed AlAmri, Mohammed Mabkhoot Mogbel, Ali Saeed Alasmary, Alhussein Ali Almonawar, Saeed Doos S. Almontashri, Hassan Mussa Al Mojamad, Turki Abdullah Al Qahtani, Abdulrahman Mohammed Alshehri, Ibrahim
BMC Endocrine Disorders.2025;[Epub] CrossRef
A population-based study on meteorological conditions in association with motor vehicle collisions among people with type 2 diabetes
Chung-Yi Li, Ya-Hui Chang, Hon-Ping Ma, Ping-Ling Chen, Chang-Ta Chiu, I-Lin Hsu
Environmental Health and Preventive Medicine.2025; 30: 91. CrossRef

Associations of fasting glucose and glycated hemoglobin with vitamin D levels according to diabetes mellitus status in Korean adults: Yerin Hwang, Jiyoung Jang, Myung-Hee Shin; Epidemiol Health. 2022;44:e2022025. Published online February 21, 2022; DOI: https://doi.org/10.4178/epih.e2022025

21,824 View
392 Download

Abstract Summary PDF Supplementary Material: Abstract
OBJECTIVES
According to previous studies, vitamin D deficiency might increase the risk of type 2 diabetes mellitus (DM). However, few studies have examined whether vitamin D continues to affect glucose control after DM diagnosis. Therefore, we examined the association between vitamin D and glucose levels in individuals with and without DM.
METHODS
We analyzed data for 32,943 adults aged 19 years and older from the 2008 to 2014 Korea National Health and Nutrition Examination Survey. Patients were classified into 3 groups according to the 25-hydroxyvitamin D concentration. DM was defined as a fasting glucose level ≥126 mg/dL, current use of DM medications or insulin injections, or a self-reported diagnosis of DM by a doctor.
RESULTS
In male DM patients, the hemoglobin A1c (HbA1c) level increased significantly as vitamin D levels became severely deficient. In male and postmenopausal female with abnormal HbA1c, those with severe vitamin D deficiency had significantly higher HbA1c levels (p for trend=0.004 and 0.022 for male and postmenopausal female, respectively). Significant differences were found between participants with normal and abnormal HbA1c levels in both male and female. However, regardless of sex or menopausal status, there was no significant association between vitamin D and fasting glucose in any of the fasting glucose subgroups.
CONCLUSIONS
Male and female with abnormal HbA1c levels showed markedly elevated blood glucose when they also had vitamin D deficiency. A more distinct difference was observed in the HbA1c subgroups than in the fasting glucose subgroups.; Summary

Korean summary
당화혈색소 비정상군에서 비타민 D가 부족할수록 혈당의 상승을 보였다. 현재까지 비타민 D와 혈당 조절과 관련하여 한국인을 대상으로 한 연구는 매우 미비한 상황이며, 한국인을 대상으로 한 연구 결과를 반영한 당뇨병 환자들의 혈당 조절 관리 지침 마련이 필요하다.

Key Message
Guidelines are needed for managing glucose control in DM patients that reflect the results of this research performed among Koreans. Additional large-scale longitudinal studies should be conducted to clarify the causal relationships underlying this association.

Dairy product consumption and type 2 diabetes among Korean adults: a prospective cohort study based on the Health Examinees (HEXA) study: Jiaqi Zhang, Kyungjoon Lim, Sangah Shin; Epidemiol Health. 2022;44:e2022019. Published online February 4, 2022; DOI: https://doi.org/10.4178/epih.e2022019

25,477 View
492 Download
14 Web of Science
15 Crossref

Abstract Summary PDF Supplementary Material

Abstract

OBJECTIVES
It has been suggested that the consumption of dairy products helps lower the prevalence of type 2 diabetes (T2D). We investigated the association between the consumption of dairy products and T2D events in middle-aged Korean adults.

METHODS

We followed up 53,288 participants (16,895 male and 36,393 female) in the Health Examinees (HEXA) study. The consumption of dairy products was assessed using the self-administered food frequency questionnaire, and T2D was defined according to the 2015 treatment guidelines of the Korean Diabetes Association. Hazard ratios (HRs) and 95% confidence intervals (CIs) between the consumption of dairy products and the risk of T2D were calculated using Cox proportional hazards models after adjusting for potential confounders. Spline regression was used to better represent the association between the consumption of dairy products and the risk of T2D.

RESULTS

Among male, those with higher consumption of dairy products had a significantly lower risk of T2D than those who consumed essentially no dairy products (HR, 0.73; 95% CI, 0.58 to 0.91). In particular, consumption of yogurt (HR, 0.75; 95% CI, 0.60 to 0.93; ptrend=0.035) and cheese (HR, 0.66; 95% CI, 0.49 to 0.89; ptrend=0.005) was negatively associated with the incidence of T2D in male. In female, daily consumption of 1 serving of yogurt decreased the risk of T2D by 11%.

CONCLUSIONS

The association between the consumption of dairy products and the risk of T2D differed by sex and dairy product type. Further prospective studies are needed to confirm these associations.

Summary

Korean summary
본 연구는 한국인유전체역학조사사업의 도시코호트 기반조사와 추적조사에 참여한 40-69세 한국 성인 53 288명의 유제품 섭취와 제2형 당뇨병 발생 위험도를 분석하였다. 요거트와 치즈를 포함한 유제품 섭취가 많을수록 남성의 제2형 당뇨병 위험도가 낮아졌다. 요거트 섭취량을 하루에 한번 증가하면 여성의 제2형 당뇨병 위험도가 감소하다. 유제품 소비와 제2형 당뇨병의 위험도의 연관성은 성별과 유제품에 따라 다르다. 이를 확인하기 위해서는 추가 연구가 필요하다.

Key Message
The study aimed to assess the association between the consumption of dairy products and type 2 diabetes events in Korean adults. Data was from the Health Examinees Study among 53 288 participants. Higher consumption of dairy products including yogurt and cheese was associated with a lower risk of developing type 2 diabetes in men. Increasing yogurt intake by one serving/day reduces the risk of type 2 diabetes in women. The association between the consumption of dairy products and the risk of type 2 diabetes differed by gender and dairy product type. Further studies are needed to confirm this.

Citations

Citations to this article as recorded by

Dairy Intake and Type 2 Diabetes Mellitus in Iranian Older Adults: Insights From the Baseline Phase of the Birjand Longitudinal Aging Study
Mahboubeh Darabi, Amirmohammad Tajik, Mehraneh Movahedi Aliabadi, Zeinab Shakeri, Maryam Mohammadi, Hossein Fakhrzadeh, Mitra Moudi, Masoumeh Khorashadizadeh, Mehdi Varmaghani, Farshad Sharifi
Endocrinology, Diabetes & Metabolism.2026;[Epub] CrossRef
The inflammatory bowel disease and gut microbiome are restored by employing metformin-loaded alginate-shelled microcapsules
Eun-Ju Kim, Hye-Seon Jeong, Ji-Yeon Park, Jae-Young Je, Chang-Hyung Choi, Sei-Jung Lee
Journal of Controlled Release.2025; 378: 490. CrossRef
Identification of Novel Genetic Variants and Food Intake Factors Associated with Type 2 Diabetes in South Korean Adults, Using an Illness–Death Model
Jeongmin Oh, Junho Cha, Sungkyoung Choi
International Journal of Molecular Sciences.2025; 26(6): 2597. CrossRef
Yogurt and Reduced Risk of Type 2 Diabetes: Exploring the Food and Drug Administration Qualified Health Claim and Potential Implications for Improving Public Health
Miguel Freitas, Annalouise O’Connor, Amanda Blechman, Christopher J Cifelli, Wendy Reinhardt Kapsak
The Journal of Nutrition.2025; 155(8): 2475. CrossRef
Usual intake of dairy products and the chance of pre-diabetes regression to normal glycemia or progression to type 2 diabetes: a 9-year follow-up
Zahra Bahadoran, Parvin Mirmiran, Fereidoun Azizi
Nutrition & Diabetes.2024;[Epub] CrossRef
Age-specific association between meal-skipping patterns and the risk of hyperglycemia in Korean adults: a national cross-sectional study using the KNHANES data
Yeonji Kang, Minji Kang, Hyunjung Lim
BMC Public Health.2024;[Epub] CrossRef
Real-time continuous glucose monitoring vs. self-monitoring of blood glucose: cost-utility in South Korean type 2 diabetes patients on intensive insulin
Ji Yoon Kim, Sabrina Ilham, Hamza Alshannaq, Richard F. Pollock, Waqas Ahmed, Gregory J. Norman, Sang-Man Jin, Jae Hyeon Kim
Journal of Medical Economics.2024; 27(1): 1245. CrossRef
The association between consumption of dairy products and risk of type 2 diabetes
Soroor Fathi, Mahsa Vahdat, Zahra Saeedirad, Naeemeh Hassanpour Ardekanizadeh, Mahdi Mousavi Mele, Soheila Shekari, Khadijeh Abbasi Mobarakeh, Hanieh Shafaei, Alireza Mosavi Jarrahi, Asma Rajabi Harsini, Sara Khoshdooz, Maryam Gholamalizadeh, Hamideh Yazd
Cardiovascular Endocrinology & Metabolism.2024;[Epub] CrossRef
Cheese consumption and multiple health outcomes: an umbrella review and updated meta-analysis of prospective studies
Mingjie Zhang, Xiaocong Dong, Zihui Huang, Xue Li, Yue Zhao, Yingyao Wang, Huilian Zhu, Aiping Fang, Edward L. Giovannucci
Advances in Nutrition.2023; 14(5): 1170. CrossRef
Effect of Milk and Cultured Milk Products on Type 2 Diabetes: A Global Systematic Review and Meta-analysis of Prospective Cohort Studies
Viswanathan Mohan, Kuzhandhaivelu Abirami, Valangaiman Sriram Manasa, Anandakumar Amutha, Balaji Bhavadharini, Rinky Rajput, Nagarajan Lakshmipriya, Chowdary Sruthi, Ranjit Mohan Anjana, Ranjit Unnikrishnan, Vasudevan Sudha, Kamala Krishnaswamy
Journal of the Indian Institute of Science.2023; 103(1): 167. CrossRef
Probiotic potential of fermented foods and their role in non-communicable diseases management: An understanding through recent clinical evidences
A. Nithya, Sourav Misra, Chirasmita Panigrahi, Chandrakant Genu Dalbhagat, Hari Niwas Mishra
Food Chemistry Advances.2023; 3: 100381. CrossRef
Dairy intake and risk of type 2 diabetes: results of a large prospective cohort
Shunming Zhang, Ge Meng, Qing Zhang, Li Liu, Hongmei Wu, Yeqing Gu, Xuena Wang, Juanjuan Zhang, Shaomei Sun, Xing Wang, Ming Zhou, Qiyu Jia, Kun Song, Yan Borné, Emily Sonestedt, Le Ma, Lu Qi, Kaijun Niu
Food & Function.2023; 14(21): 9695. CrossRef
Association of milk consumption with management and incidence of hypertension among South Korean adults: A prospective analysis of the health examinees study cohort
Hyein Jung, Geongu Lee, Kyungjoon Lim, Sangah Shin
Nutrition, Metabolism and Cardiovascular Diseases.2022; 32(11): 2515. CrossRef
Association between dairy consumption and the risk of diabetes: A prospective cohort study from the China Health and Nutrition Survey
Yucheng Yang, Xiaona Na, Yuandi Xi, Menglu Xi, Haibing Yang, Zhihui Li, Ai Zhao
Frontiers in Nutrition.2022;[Epub] CrossRef
Association of dairy consumption patterns with the incidence of type 2 diabetes: Findings from Alberta's Tomorrow Project
Emad Yuzbashian, Mohammadreza Pakseresht, Jennifer Vena, Catherine B. Chan
Nutrition, Metabolism and Cardiovascular Diseases.2022; 32(12): 2760. CrossRef

The predictive value of resting heart rate in identifying undiagnosed diabetes in Korean adults: Korea National Health and Nutrition Examination Survey: Dong-Hyuk Park, Wonhee Cho, Yong-Ho Lee, Sun Ha Jee, Justin Y. Jeon; Epidemiol Health. 2022;44:e2022009. Published online January 3, 2022; DOI: https://doi.org/10.4178/epih.e2022009

25,643 View
425 Download
2 Web of Science
3 Crossref

Abstract Summary PDF Supplementary Material

Abstract

OBJECTIVES
The purpose of this study was (1) to examine whether the addition of resting heart rate (RHR) to the existing undiagnosed diabetes mellitus (UnDM) prediction model would improve predictability, and (2) to develop and validate UnDM prediction models by using only easily assessable variables such as gender, RHR, age, and waist circumference (WC).

METHODS

Korea National Health and Nutrition Examination Survey (KNHANES) 2010, 2012, 2014, 2016 data were used to develop the model (model building set, n=19,675), while the data from 2011, 2013, 2015, 2017 were used to validate the model (validation set, n=19,917). UnDM was defined as a fasting glucose level ≥126 mg/dL or glycated hemoglobin ≥6.5%; however, doctors have not diagnosed it. Statistical package for the social sciences logistic regression analysis was used to determine the predictors of UnDM.

RESULTS

RHR, age, and WC were associated with UnDM. When RHR was added to the existing model, sensitivity was reduced (86 vs. 73%), specificity was increased (49 vs. 65%), and a higher Youden index (35 vs. 38) was expressed. When only gender, RHR, age, and WC were used in the model, a sensitivity, specificity, and Youden index of 70%, 67%, and 37, respectively, were observed.

CONCLUSIONS

Adding RHR to the existing UnDM prediction model improved specificity and the Youden index. Furthermore, when the prediction model only used gender, RHR, age, and WC, the outcomes were not inferior to those of the existing prediction model.

Summary

Korean summary
당뇨병 미인지 또는 미진단은 적절한 치료 시작 시기를 늦추고 당뇨병 합병증 발생의 위험을 높이기 때문에, 각국은 당뇨병 예측 모형을 개발하여 당뇨병을 조기에 예측하고, 치료 시기를 앞당기기 위해 노력하고 있다. 본 연구는 기존의 한국인 당뇨병 예측 모형에 안정시심박수를 추가 변수로 포함시켜, 예측 모형의 성능이 일부개선되는 것을 확인하였고, 더 나아가 나이, 허리 둘레, 그리고 안정시심박수를 포함하여 예측 모형을 개발하고, 그 성능을 확인하였다. 본 연구에서는 간단하게 측정이 가능한 허리 둘레와 안정시심박수 그리고 나이만 포함한 예측 모형이 기존의 예측 모형과 비교해 성능이 열등하지 않은 것을 확인하였다.

Key Message
Higher RHR is associated with increased risk of diabetes. When RHR is added to the Korean undiagnosed diabetes risk score model (Age, Family history of diabetes, Hypertension, Waist circumference, Smoking, Alcohol consumption), the model somewhat increased its predictability of undiagnosed diabetes. Furthermore, the prediction model developed only using age, waist circumference and RHR, which anyone can easily measure or access, had similar predictability to the previous undiagnosed diabetes risk prediction model. The results of this study may help develop future strategies or applications for predicting early undiagnosed diabetes.

Citations

Citations to this article as recorded by

Improving T2D machine learning-based prediction accuracy with SNPs and younger age
Cynthia AL Hageh, Andreas Henschel, Hao Zhou, Jorge Zubelli, Moni Nader, Stephanie Chacar, Nantia Iakovidou, Haralampos Hatzikirou, Antoine Abchee, Siobhán O’Sullivan, Pierre A. Zalloua
Computational and Structural Biotechnology Journal.2025; 27: 2772. CrossRef
Comparisons of the prediction models for undiagnosed diabetes between machine learning versus traditional statistical methods
Seong Gyu Choi, Minsuk Oh, Dong–Hyuk Park, Byeongchan Lee, Yong-ho Lee, Sun Ha Jee, Justin Y. Jeon
Scientific Reports.2023;[Epub] CrossRef
Factors related to undiagnosed diabetes in Korean adults: a secondary data analysis
Bohyun Kim
Journal of Korean Biological Nursing Science.2023; 25(4): 295. CrossRef

Effects of early medication treatment and metformin use for cancer prevention in diabetes patients: a nationwide sample cohort study in Korea using extended landmark time analysis: Hwa Jeong Seo, Hyun Sook Oh; Epidemiol Health. 2021;43:e2021103. Published online December 17, 2021; DOI: https://doi.org/10.4178/epih.e2021103

27,103 View
222 Download
7 Web of Science
3 Crossref

Abstract Summary PDF Supplementary Material

Abstract

OBJECTIVES
This study investigated the effectiveness of early medication treatment and metformin use for cancer prevention in type 2 diabetes patients.

METHODS

Population-based cohort data were used from the Korean National Health Insurance Service-National Sample Cohort database (KNHIS-NSC) for 2002-2013. Patient-specific medication prescription status was defined by the landmark time (LMT; a fixed time after cohort entry), considering both pre- and post-LMT prescriptions to control methodological biases in observational research. The LMT was set to 2 years. Logistic regression analysis with multivariable adjustment was conducted to analyze cancer incidence by patient-specific medication prescription status.

RESULTS

Only 33.4% of the subjects were prescribed medication early (before the LMT) with compliance. Cancer incidence in individuals with early prescription and compliance was 25% lower (odds ratio [OR], 0.75; 95% confidence interval [CI], 0.67 to 0.84) than in those without. As early-prescribed medications, metformin monotherapy and metformin combination therapy were associated with 34% (OR, 0.66; 95% CI, 0.51 to 0.83) and 25% (OR, 0.75; 95% CI, 0.64 to 0.88) lower cancer risk than non-use, respectively. Patients who were prescribed late (post-LMT) but did not comply with the prescription had a 24% (OR, 1.24; 95% CI, 0.97 to 1.58) higher cancer incidence than non-users. Among patients who started monotherapy early without changes throughout the entire follow-up period, those who started on metformin had a 37% (OR, 0.63; 95% CI, 0.41 to 0.99) lower risk of cancer than non-metformin users.

CONCLUSIONS

Doctors must prescribe antidiabetic medication early, and patient compliance is required, regardless of the prescription time, to prevent cancer. Metformin monotherapy or combination therapy is recommended as an early prescription.

Summary

Korean summary
당뇨 환자는 암 발병 위험이 높으며 암은 주요 사망 원인이다. 당뇨환자의 암발생 예방을 위한 관리로서, 당뇨병 진단 후 약물 치료 시기에 대한 연구는 부족하다. 또한, 전 세계적으로 가장 흔히 처방되는 당뇨병 치료제인 메트포민은 암 예방 효과가 있다고 알려져 왔으나 관측연구에서 발생하는 선택 편향의 문제가 제기되었고, 최근 일부 연구에서 기존의 암 예방 효과와 상충되는 결과가 나오고 있어 논쟁이 이어지고 있다. 본 연구는 선택 편향을 통제한 코호트 연구에서 조기 약물 치료와 메트포민 사용이 당뇨환자의 암 예방에 효과적임을 밝혔다. 따라서 의사들은 처음 당뇨 진단을 받은 환자에게 조기에 약물 처방을 하고, 환자들은 처방에 잘 따라야 한다. 조기 처방 약물로서 메트포민이 권장된다.

Key Message
Diabetic patients have a high risk of developing cancer, and cancer is the leading cause of death. There are few studies on the timing of medication treatment after diagnosis of diabetes. In addition, metformin, the most commonly prescribed diabetes treatment worldwide, is known to have cancer-preventive effects, but the problem of selection bias that occurs in observational studies has been raised, and some studies have recently been contradicting the existing cancer-preventing effects of metformin. This study, in a cohort study controlled for selection bias, demonstrated that early medication treatment and metformin use were effective in preventing cancer in diabetic patients.

Citations

Citations to this article as recorded by

Association between metformin use and the risk of developing open-angle glaucoma among patients with diabetes: a retrospective cohort study and meta-analysis
Hong Kyu Kim, Wanhyung Lee, Ik Hee Ryu, Jin Kuk Kim, Hyungsu Kim, Tae Keun Yoo
International Ophthalmology.2024;[Epub] CrossRef
Metformin and HER2-positive breast cancer: Mechanisms and therapeutic implications
Sara S Bashraheel, Hadeel Kheraldine, Sarah Khalaf, Ala-Eddin Al Moustafa
Biomedicine & Pharmacotherapy.2023; 162: 114676. CrossRef
Effects of millimeter-wave for preventing joint stiffness in the immobilized knee rat model
Xiao-ping Shui, Feng Ye, Chun-ying Li, Xin Zhang, Min-jia Wang, Bin Li, Ke Chen, Ying-ying Liao
The Knee.2023; 42: 236. CrossRef

Editorial

Spatiotemporal analyses of the epidemiological characteristics of diabetes mellitus: Sang Youl Rhee; Epidemiol Health. 2021;43:e2021102. Published online December 16, 2021; DOI: https://doi.org/10.4178/epih.e2021102

21,097 View
169 Download
1 Web of Science
1 Crossref

Abstract Summary PDF

Abstract

Research based on spatiotemporal analysis has been conducted to identify various factors that can affect an individual’s or community’s degree of health and disease. These spatiotemporal studies can effectively illustrate patterns in disease frequency, features, and temporal flow in different parts of a country. Furthermore, identifying these regional characteristics can aid in the development of disease prevention or intervention strategies.

Summary

Korean summary
1. 시공간 분석은 국가 혹은 지역의 질병 빈도, 특징 및 시간 흐름의 패턴을 효과적으로 설명할 수 있다. 2. 시공간 분석은 질병의 예방 또는 중재 전략 개발에 도움이 될 수 있다.

Key Message
1. Spatiotemporal analyses can effectively illustrate patterns in disease frequency, features, and temporal flow in different parts of a country. 2. Spatiotemporal analysis can aid in disease prevention or development of intervention strategies.

Citations

Citations to this article as recorded by

Epidemiological characteristics and spatiotemporal analysis of mumps at township level in Wuhan, China, 2005–2019
Ying Peng, Peng Wang, De-guang Kong, Wen-zhen Li, Dong-ming Wang, Li Cai, Sha Lu, Bin Yu, Bang-hua Chen, Pu-Lin Liu
Epidemiology and Infection.2023;[Epub] CrossRef

Original Article

Spatiotemporal trends in diabetes-related mortality by school district in the state of Michigan, United States: Nurjannah Nurjannah, Kathleen M. Baker, Duduzile Phindi Mashinini; Epidemiol Health. 2021;43:e2021098. Published online November 9, 2021; DOI: https://doi.org/10.4178/epih.e2021098

26,564 View
160 Download
4 Web of Science
4 Crossref

Abstract Summary PDF

Abstract

OBJECTIVES
This study examined the spatiotemporal epidemiological status of diabetes-related death in relation to school district boundaries in the state of Michigan, United States.

METHODS

A retrospective observational study was conducted using death records spanning the years 2007-2014 in Michigan, with school districts as the geographic unit of analysis. Geocoding was performed for each death record. Cluster analysis used spatial autocorrelation with local Moran’s I, and spatiotemporal analysis used the Space Time Pattern Mining tool in ArcGIS Pro 2.1.

RESULTS

The study revealed spatial clusters of high-high locations of diabetes-related mortality rate by school district in Michigan from 2007 to 2014. Spatiotemporal analysis showed grids with intensifying, consecutive, sporadic, and persistent hotspots of diabetes-related death in the Lansing, Royal Oak, Flint City, Berkley, Detroit City, East Lansing, South Lake, and Holt public school districts. These school districts should be prioritized for school-based diabetes prevention programs

CONCLUSIONS

The study demonstrated the presence of various hotspots of diabetes-related deaths within the state of Michigan across the 8-year period of analysis. Understanding spatial and temporal hotspots could further improve our ability to evaluate diabetes burden across both time and space.

Summary

Key Message
Using existing secondary data with spatio-temporal analysis, the study identified diabetes-related death varies across space and time within the state of Michigan, USA at the school district level. This approach provided policy-relevant information to target high-risk school-district when having limited resources to prevent diabetes at schools.

Citations

Citations to this article as recorded by

Age-specific life expectancies across school districts in the United States: Applying a population weighted geographic crosswalk to aggregate census tract indicators
Logan Beyer, Jeff Blossom, Junyi Chen, Rockli Kim, S.V. Subramanian
SSM - Population Health.2026; 33: 101896. CrossRef
Spatiotemporal Epidemiological Trends of Mpox in Mainland China: Spatiotemporal Ecological Comparison Study
Shuli Ma, Jie Ge, Lei Qin, Xiaoting Chen, Linlin Du, Yanbo Qi, Li Bai, Yunfeng Han, Zhiping Xie, Jiaxin Chen, Yuehui Jia
JMIR Public Health and Surveillance.2024; 10: e57807. CrossRef
Asthma Hot Spots in New York Before and During the COVID-19 Pandemic
Samira Skochko, Trang Nguyen, Stephanie Mack, Brooke Turcotte, Catherine Adler, Eli S. Rosenberg, Christopher Joseph, Lynley Siag, Alexandra Dubuisson, Victoria L. Wagner
Preventing Chronic Disease.2024;[Epub] CrossRef
Spatiotemporal analyses of the epidemiological characteristics of diabetes mellitus
Sang Youl Rhee
Epidemiology and Health.2021; 43: e2021102. CrossRef

Systematic Review

The effect of peer support in diabetes self-management education on glycemic control in patients with type 2 diabetes: a systematic review and meta-analysis: Akhmad Azmiardi, Bhisma Murti, Ratih Puspita Febrinasari, Didik Gunawan Tamtomo; Epidemiol Health. 2021;43:e2021090. Published online October 22, 2021; DOI: https://doi.org/10.4178/epih.e2021090

43,536 View
519 Download
48 Web of Science
59 Crossref

Abstract Summary PDF Supplementary Material

Abstract

OBJECTIVES
Diabetes self-management education (DSME) programs are a strategy to maintain healthy behaviors. Nevertheless, limited evidence has been reported from systematic evaluations of the effects of DSME integrated with peer support on glycemic control. This study aimed to review the effectiveness of DSME interventions integrated with peer support on glycemic control in patients with type 2 diabetes.

METHODS

A systematic search was carried out in electronic databases, including PubMed, Cochrane Library, ProQuest, SpringerLink, ScienceDirect, Scopus, and Google Scholar, for English-language articles published from 2005 until 2020. The effect size was estimated as the standard mean difference (SMD). The Cochrane Collaboration’s Risk of Bias tool was employed to assess the risk of bias.

RESULTS

Twelve studies were included in this study. DSME integrated with peer support effectively reduced glycated hemoglobin A1c (HbA1c) levels, with a statistically significant effect (SMD, -0.41; 95% confidence interval [CI], -0.69 to -0.13; p<0.001). Programs with a sample size <100 (SMD, -0.45; 95% CI, -0.79 to -0.11; p=0.009), duration of intervention ≤6 months (SMD, -0.52; 95% CI, -0.96 to -0.07; p=0.020), baseline HbA1c <8.5% (SMD, -0.42; 95% CI, -0.77 to -0.07; p=0.020), delivery by group (SMD, -0.28; 95% CI, -0.51 to -0.06; p=0.010), and high frequency of contact (SMD, -0.29; 95% CI, -0.48 to -0.10; p=0.003) had statistically significant effects on reducing HbA1c levels in patients with type 2 diabetes.

CONCLUSIONS

DSME integrated with peer support effectively enhances glycemic control in patients with type 2 diabetes. Programs with smaller participants groups, shorter interventions, weekly meetings, and closer group sessions improved glycemic control in patients with type 2 diabetes.

Summary

Key Message
We reviewed and assessed the quality of the twelve articles included in this systematic review and meta-analysis. The findings of this review show that peer support integrated with diabetes self-management education programs can significantly enhance glycemic control in type 2 diabetes patients. Peer support is a critical component of a successful diabetes self-management programme in patients with type 2 diabetes. interventions programme with smaller groups, shorter durations, lower HbA1c baseline levels, group sessions, and high frequencies of sessions significantly enhanced glycemic control.

Citations

Citations to this article as recorded by

Is There a Relationship Between Social Health and Musculoskeletal Discomfort and Incapability? A Systematic Review
Andrew Samson, Ananya Murthy, David Ring, Niels Brinkman
Clinical Orthopaedics & Related Research.2026; 484(3): 465. CrossRef
1. Improving Care and Promoting Health in Populations: Standards of Care in Diabetes—2026
Mandeep Bajaj, Rozalina G. McCoy, Kirthikaa Balapattabi, Raveendhara R. Bannuru, Natalie J. Bellini, Allison K. Bennett, Elizabeth A. Beverly, Kathaleen Briggs Early, Sathyavathi ChallaSivaKanaka, Osagie Ebekozien, Justin B. Echouffo-Tcheugui, Brendan M.
Diabetes Care.2026; 49(Supplement): S13. CrossRef
Exploring the REACHOUT Mental Health Support App for Type 1 Diabetes From the Perspectives of Recipients and Providers of Peer Support: Qualitative Study
Debbie Lam, Poonamdeep Jhajj, Diana Sherifali, Frances S Chen, Tricia S Tang
JMIR Diabetes.2026; 11: e72779. CrossRef
Conceptual validation of a family-centered intervention for adults with type 1 and type 2 diabetes mellitus: insights from focus groups with healthcare professionals, patients, and families
Vânia Lídia Soares, Carlos Alberto da Sequeira, Maria Carminda Morais, Maria do Céu Barbieri-Figueiredo
BMC Primary Care.2026;[Epub] CrossRef
The Effectiveness of Peer Support on Self‐Management and Psychosocial Outcomes in Maintenance Hemodialysis Patients: A Systematic Review and Meta‐Analysis
Tiqiong Gong, Hong Wang, Qingshu Zhang, Yansheng Ye
Hemodialysis International.2026; 30(2): 329. CrossRef
Exploring stakeholder perceptions of peer support initiatives in the management of diabetes in low- and middle-income countries: An online survey study
Bishal Gyawali, Soahum Bagchi, Zainab Dakhil, Israa Yaseen, Fathima Aaysha Cader, Lilian Pinto da Silva, Pooja Dewan, Diana Sherifali, Sheila Klassen, Julia Robinson
PLOS Global Public Health.2026; 6(2): e0005840. CrossRef
Effect of diabetes self-management education in type 2 diabetes management - a systematic umbrella review of meta-analysis
Liang Ma, Wei-Shun Zhao, Ran Wang, Sha-Sha Huo, Si-Yin Chu, Li-Hua Shi, Yun Chen, Yin-Qin Zhong
BMC Endocrine Disorders.2026;[Epub] CrossRef
A three-arm, parallel group, cluster randomized controlled trial to evaluate digital and complex lifestyle interventions as compared with usual care for type 2 diabetes prevention: protocol for the Daqing Diabetes Prevention Study II (Daqing DPS-II)
Juan Zhang, Di Li, Yachen Wang, Xin Chai, Dongli Zhu, Chunyu Yang, Minlin Chen, Xinran Xiang, Ji Zhang, Xuejun Yin, Jinping Wang, Alon Rasooly, Jaana Lindström, Zhiwei Yang, Ruitai Shao
Trials.2026;[Epub] CrossRef
The psychological burden of diabetes: common mental health disorders, their impact on disease outcomes and strategies for intervention
Javed Latoo, Yasser Saeed Khan, Armaan Latoo, Majid Alabdulla, Farida Jan, Nasseer Masoodi, Daljit Sura, Shariful Islam, Ovais Wadoo
Journal of Diabetes & Metabolic Disorders.2026;[Epub] CrossRef
Evaluation of Diabetes Self‐Care Activities and Glycemic Control Profiles in People With Type 2 Diabetes Mellitus
Sonu Neupane, Prasanna Dahal, Mukesh Koirala, Rahi Bikram Thapa, Dojindra Basnet, Sashi Sharma Rijal
Health Science Reports.2026;[Epub] CrossRef
Factors influencing the implementation of best clinical practices for hip fracture management in resource-constrained hospitals in China and co-design of quality improvement interventions: a qualitative study
Tingzhuo Liu, Gang Liu, Ning Tang, Boya Nan, Chenguang Hao, Xuecheng Sun, Baorui Xing, Dongsheng Wu, Shuyuan Wang, Liming Li, Kangquan Shou, Yang Li, Lei Yang, Zhigang Zhong, Wei Tian, Qiang Li, Lei Si, Ronald Man Yeung Wong, Xinyi Zhang, Jing Zhang, Shan
The Lancet Regional Health - Western Pacific.2026; 69: 101847. CrossRef
Effectiveness of family and peer support intervention on glycemic control, self-management, and quality of life in type 2 diabetes in rural Indonesia: A randomized controlled trial
Akhmad Azmiardi, Ratih P. Febrinasari, Bhisma Murti
Journal of Family and Community Medicine.2026; 33(2): 84. CrossRef
Self-management education and support for type 2 diabetes in Thailand: a cluster randomized trial (2019–2021)
Piyachon Aramrat, Iliatha Papachristou Nadal, Poppy Alice Carson Mallinson, Kanokporn Pinyopornpanish, Orawan Quansri, Kittipan Rerkasem, Supattra Srivanichakorn, Win Techakehakij, Nuthchanath Wichit, Kamlesh Khunti, Chaisiri Angkurawaranon, Sanjay Kinra
The Lancet Regional Health - Southeast Asia.2026; 49: 100778. CrossRef
Pengaruh Edukasi Terstruktur Berbasis Booklet Terhadap Kepatuhan, Kualitas Hidup, Dan Kadar Glukosa Darah Sewaktu Pasien Diabetes Melitus Tipe 2 Di Puskesmas Kota Tasikmalaya, Jawa Barat, Indonesia
Listya Permatasari, Tri Murti Andayani, Fita Rahmawati
Journal of Pharmaceutical and Sciences.2026; : 1493. CrossRef
The Underutilization of National Diabetes Prevention Program Among Women With a History of Gestational Diabetes Mellitus: An In-Depth Focus Group Analysis
Priyadharshini Narayanan, Sahitya R. Kothapalli, Harmonie B. Strohl, Linda L. Hill
AJPM Focus.2025; 4(1): 100279. CrossRef
1. Improving Care and Promoting Health in Populations: Standards of Care in Diabetes—2025
Nuha A. ElSayed, Rozalina G. McCoy, Grazia Aleppo, Kirthikaa Balapattabi, Elizabeth A. Beverly, Kathaleen Briggs Early, Dennis Bruemmer, Osagie Ebekozien, Justin B. Echouffo-Tcheugui, Laya Ekhlaspour, Rajesh Garg, Kamlesh Khunti, Rayhan Lal, Ildiko Lingva
Diabetes Care.2025; 48(Supplement): S14. CrossRef
Practicing Meta-Analytics with Rectification
Ramalingam Shanmugam, Karan P. Singh
Publications.2025; 13(1): 2. CrossRef
Lessons learned in recruiting and retaining Black men in behavioral diabetes intervention research
Jaclynn M. Hawkins, Alana M. Ewen, Martha Funnell, Robin Nwankwo, Gretchen Piatt
Contemporary Clinical Trials Communications.2025; 45: 101487. CrossRef
A Randomized Controlled Trial in a 14-Month Longitudinal Design to Analyze the Effects of a Peer Support Instant Messaging Service Intervention to Improve Diabetes Self-Management and Support
Elisabeth Höld, Ursula Hemetek, Katharina Tremmel, Tatjana Aubram, Johanna Grüblbauer, Martin Wiesholzer, Manuel Schwanda, Stefan Stieger
Diabetology.2025; 6(5): 44. CrossRef
Psychological Care Needs and Mental Health Service Use Among Adults with Diabetes: Evidence from the Diabetes, Distress, and Disparities (3D) Study
Briana Mezuk, Kara M. Mannor, Rebecca Hebert, Lauren Kouassi, Bella Flores, Emma Spring, Alejandro Rodríguez-Putnam
Healthcare.2025; 13(12): 1427. CrossRef
Type 2 Diabetes Management: Is it Fair to Put the Onus on the Patients Alone?
Ragini Bhake, Shalbha Tiwari, Neelam Patil, Shailesh Deshpande
Chronicle of Diabetes Research and Practice.2025; 4(2): 59. CrossRef
Evaluation of the NHS England Low-Calorie Diet implementation pilot: a coproduced mixed-method study
Louisa J Ells, Tamara Brown, Jamie Matu, Ken Clare, Simon Rowlands, Maria Maynard, Karina Kinsella, Kevin Drew, Jordan R Marwood, Pooja Dhir, Tamla S Evans, Maria Bryant, Wendy Burton, Duncan Radley, Jim McKenna, Catherine Homer, Adam Martin, Davide Tebal
Health and Social Care Delivery Research.2025; : 1. CrossRef
The effect of peer support on HbA1c levels in middle-aged and elderly patients with type 2 diabetes: a systematic review and meta-analysis
Jiankun Luo, Jiyuan Shu, Weiqing Pan, Duanqin Guan, Congmin Liang, Dongyan Zheng, Kailun Huang, Yixi Lai, Bing Meng, Renjian Lu, Ziwei Cai, Lifei Xing, Jialong Chen, He Zhang
PeerJ.2025; 13: e19803. CrossRef
Pentingnya Kesehatan Mental Dalam Manajemen Diri Diabetes Mellitus
Iswanto, Ratna Puji Priyanti, Eka Mei Dianita
DEDIKASI SAINTEK Jurnal Pengabdian Masyarakat.2025; 4(2): 158. CrossRef
The role of dietary tracking on changes in dietary behaviour in a community-based diabetes prevention and management intervention
Ranjita Misra, Delores James
Public Health Nutrition.2025;[Epub] CrossRef
Peer-led Diabetes Self-Management Education and Support Enhances Cardiometabolic Markers in Adults With Type 2 Diabetes: A Quasi-Experimental Study
Elizabeth Wanjiru Maina, Samuel Kimani, James Mwaura
INQUIRY: The Journal of Health Care Organization, Provision, and Financing.2025;[Epub] CrossRef
“I no longer feel that diabetes is the end of everything, but rather the beginning of a healthier lifestyle”: Experience of type 2 diabetes mellitus patient to achieve glycemic control
Rifky Octavia Pradipta, Sylvia Dwi Wahyuni, Hakim Zulkarnain, Ferry Efendi, Mei Chan Chong
Electronic Journal of General Medicine.2025; 22(6): em705. CrossRef
Reimagining Diabetes Self-Management Education and Support (DSMES) Services: Complementing the Four Critical Times With Continuous, Peer-Driven Support
Janice MacLeod, Donna Rice, Deborah Greenwood
ADCES in Practice.2025;[Epub] CrossRef
Systematic review of healthcare-led and lay-led interventions for type 2 diabetes in community settings
Xuanning Luo, Chuanlei Zheng, Qingfeng Wu
Scientific Reports.2025;[Epub] CrossRef
Impact of Diabetes Self-Management Education on A1C Levels Among Black/African Americans: A Systematic Review
Hilda M. Okeyo, Martha Biddle, Lovoria B. Williams
The Science of Diabetes Self-Management and Care.2024; 50(1): 87. CrossRef
The effects of diabetes clubs on peer-support, disclosure of diabetes status, and sources of information regarding diabetes management: results of a pilot-intervention in rural Vietnam
D.W. Meyrowitsch, N.-A. Thi Dang, T.V. Phong, J. Nielsen, J. Søndergaard, N.D. Cuong, H. Le Minh, T.K.D. Vu, I.C. Bygbjerg, T.M. Gammeltoft, N.D. Thanh
Public Health.2024; 228: 171. CrossRef
Effect of peer support interventions in patients with type 2 diabetes: A systematic review
Chen Chen, Yuan Zhou, Jia-Yi Xu, Hai-Yan Song, Xu-Wen Yin, Ze-Juan Gu
Patient Education and Counseling.2024; 122: 108172. CrossRef
Prioritizing Patient Experiences in the Management of Diabetes and Its Complications: An Endocrine Society Position Statement
Rita R Kalyani, Myriam Z Allende-Vigo, Kellie J Antinori-Lent, Kelly L Close, Sandeep R Das, Phyllisa Deroze, Steven V Edelman, Nuha A El Sayed, David Kerr, Joshua J Neumiller, Anna Norton
The Journal of Clinical Endocrinology & Metabolism.2024; 109(5): 1155. CrossRef
Self-help friendliness and cooperation with self-help groups among rehabilitation clinics in Germany (KoReS): a mixed-methods study protocol
Elâ Ziegler, Thea Bartzsch, Alf Trojan, Nicole Usko, Ines Krahn, Sabine Bütow, Christopher Kofahl
BMJ Open.2024; 14(3): e083489. CrossRef
Peer support for adults with type 2 diabetes starting continuous glucose monitoring—An exploratory randomised controlled trial
Nanna Lind, Merete Bechmann Christensen, Dorte Lindqvist Hansen, Ingrid Willaing, Kirsten Nørgaard
Diabetic Medicine.2024;[Epub] CrossRef
Implementing (and evaluating) peer support with people living with noncommunicable diseases in humanitarian settings
Benjamin Schmid, Carla Njeim, Lavanya Vijayasingham, Leah Anku Sanga, Rima Kighsro Naimi, Fouad M. Fouad, Chaza Akik, Carla Zmeter, Sigiriya Aebischer Perone, Lars Bruun Larsen, Jytte Roswall, Éimhín Ansbro, Pablo Perel
Journal of Migration and Health.2024; 9: 100229. CrossRef
Recent Findings on the Effectiveness of Peer Support for Patients with Type 2 Diabetes
James J. Werner, Kelsey Ufholz, Prashant Yamajala
Current Cardiovascular Risk Reports.2024; 18(5): 65. CrossRef
Peer support for people living with hepatitis B virus—A foundation for treatment expansion
Louise O. Downs, Kenneth Kabagambe, Sarah Williams, Elizabeth Waddilove, Marion Delphin, Sheila F. Lumley, Richard Ndungutse, Beatrice Kimono, Robert Newton, Joy Ko, Emily Martyn, Jessica Carter, Agnieszka Kemper, Fernando Monteiro, Sive O'Regan, Julian S
Journal of Viral Hepatitis.2024; 31(8): 490. CrossRef
A qualitative study on inner experience of self-management behavior among elderly patients with type 2 diabetes in rural areas
Zi-chen Zhang, Qiu-hui Du, Hong-hong Jia, Yu-min Li, Yu-qin Liu, Shao-bo Li
BMC Public Health.2024;[Epub] CrossRef
Does type 2 diabetes duration influence the effectiveness of an aerobic exercise intervention: Results from the INTENSITY study
Amy M. Thomson, Brittany V. Rioux, Travis J. Hrubeniuk, Danielle R. Bouchard, Martin Sénéchal, Hidetaka Hamasaki
PLOS ONE.2024; 19(6): e0304341. CrossRef
Therapeutic patient education programs on diabetes in sub-Saharan Africa: A systematic review
Omomene Iwelomen, Jean Toniolo, Pierre-Marie Preux, Pascale Beloni, Francis Xavier Kasujja
PLOS ONE.2024; 19(6): e0299526. CrossRef
Patient-centered care in diabetes care-concepts, relationships and practice
Tsung-Tai Chen, Wei-Chih Su, Mei-I Liu
World Journal of Diabetes.2024; 15(7): 1417. CrossRef
Effectiveness of a health literacy intervention to improve diabetes outcomes in rural family medicine clinics: a randomized pragmatic trial
Laura M. Curtis, Terry C. Davis, Connie L. Arnold, Jennifer M. Gan, Jean C. McSweeney, Scott Hur, Mary J. Kwasny, Michael S. Wolf, Kristie Hadden
Health Literacy and Communication Open.2024;[Epub] CrossRef
Challenges in Insulin Therapy: Perspectives of Malaysian Diabetes Educators
Nur Shazwaniza Yahya, Zamzaliza Abdul Mulud, Ahmad Zamir Che Daud, Fauziah Ahmad
The Open Nursing Journal.2024;[Epub] CrossRef
Effectiveness of Multilevel and Multidomain Interventions to Improve Glycemic Control in U.S. Racial and Ethnic Minority Populations: A Systematic Review and Meta-analysis
Eli M. Falk, Erin M. Staab, Amber N. Deckard, Sofia I. Uranga, Nikita C. Thomas, Wen Wan, Andrew J. Karter, Elbert S. Huang, Monica E. Peek, Neda Laiteerapong
Diabetes Care.2024; 47(9): 1704. CrossRef
Factors associated with disease knowledge and attitude among ambulatory patients with type 2 diabetes – a multicenter study
Akinniyi A. Aje, Titilayo O. Fakeye
BMC Endocrine Disorders.2024;[Epub] CrossRef
Comparative Effects of Diabetes Self‐Management Programs on Type 2 Diabetes Clinical Outcomes: A Systematic Review and Network Meta‐Analysis
Debby Syahru Romadlon, Yu‐Kang Tu, Yang‐Ching Chen, Faizul Hasan, Rudy Kurniawan, Hsiao‐Yean Chiu
Diabetes/Metabolism Research and Reviews.2024;[Epub] CrossRef
A pilot community-based Diabetes Prevention and Management Program for adults with diabetes and prediabetes
Ranjita Misra, Samantha Shawley-Brzoska
Journal of Clinical and Translational Science.2024;[Epub] CrossRef
Simulación basada en aprendizaje experiencial en la educación en diabetes para promover la empatía hacia el paciente
María Rosario Sánchez, Freddy Contreras
Revista Digital de Postgrado.2024;[Epub] CrossRef
The current diabetes education experience: Findings of a cross-sectional survey of adults with type 2 diabetes
Kelley M. Baker, Carine M. Nassar, Neelam Baral, Michelle F. Magee
Patient Education and Counseling.2023; 108: 107615. CrossRef
2023 update on Italian guidelines for the treatment of type 2 diabetes
Edoardo Mannucci, Riccardo Candido, Lina delle Monache, Marco Gallo, Andrea Giaccari, Maria Luisa Masini, Angela Mazzone, Gerardo Medea, Basilio Pintaudi, Giovanni Targher, Marina Trento, Giuseppe Turchetti, Valentina Lorenzoni, Matteo Monami
Acta Diabetologica.2023; 60(8): 1119. CrossRef
Mechanisms Activated in the Interaction between Peer Supporters and Peers: How do the Peer Supporters Perceive and Perform Their Role in an Intervention Targeted Socially Vulnerable People with Type 2 Diabetes: A Realist-Informed Evaluation
Stine Dandanell Garn, Charlotte Glümer, Sarah Fredsted Villadsen, Majken Lillholm Pico, Ulla Christensen, Gianpiero Greco
Health & Social Care in the Community.2023; 2023: 1. CrossRef
Fresh Start: A Comprehensive Pilot Produce Prescription Program to Improve Food Literacy and Glycemic Control in Rural, Uninsured Patients
Lauren R. Sastre, Brandon J. Stroud
American Journal of Lifestyle Medicine.2023;[Epub] CrossRef
Current evidence for designing self-management support for underserved populations: an integrative review using the example of diabetes
Ian Litchfield, Tim Barrett, Julian Hamilton-Shield, Theresa Moore, Parth Narendran, Sabi Redwood, Aidan Searle, Suma Uday, Jess Wheeler, Sheila Greenfield
International Journal for Equity in Health.2023;[Epub] CrossRef
Diabetes care components effectively implemented in the ASEAN health systems: an umbrella review of systematic reviews
Vannarath Te, Sokvy Ma, Ir Por, Wim Van Damme, Edwin Wouters, Josefien van Olmen
BMJ Open.2023; 13(10): e071427. CrossRef
The impact of veteran support and resources for diabetes (iNSPiRED) on diabetes distress: Results from a randomized, parallel-group trial
Mark E. Kunik, Tracy L. Evans, Israel C. Christie, Gala True, Andrea Bradford, Madhuri M. Vasudevan, Natalie E. Hundt
General Hospital Psychiatry.2023; 85: 55. CrossRef
A stepped wedge cluster randomized trial to evaluate the effectiveness of a community leader-driven kit-based diabetes self-management education approach in improving diabetes control and care: study protocol for the DElhi Diabetes INTervention Trial (DED
Jitender Nagpal, Swapnil Rawat, Lovely Gupta, Avantika Negi, Divya Shashi Oraon
Trials.2023;[Epub] CrossRef
Family doctors’ attitudes toward peer support programs for type 2 diabetes and/or coronary artery disease: an exploratory survey among German practitioners
K. Majjouti, L. Küppers, A. Thielmann, M. Redaélli, F. Vitinius, C. Funke, I. van der Arend, L. Pilic, M. Hessbrügge, S. Stock, B. Weltermann, D. Wild
BMC Primary Care.2022;[Epub] CrossRef
From clinic to community: A randomized controlled trial of a peer support model for adults with type 2 diabetes from specialty care settings in British Columbia
Tricia S. Tang, Rowshanak Afshar, Thomas Elliott, Jason Kong, Sabrina Gill
Diabetic Medicine.2022;[Epub] CrossRef

Original Articles

Association between a family history of diabetes and carotid artery atherosclerosis in Korean adults: Sun Young Shim, Ga Bin Lee, Jee-Seon Shim, Sun Jae Jung, Hyeon Chang Kim; Epidemiol Health. 2021;43:e2021049. Published online August 3, 2021; DOI: https://doi.org/10.4178/epih.e2021049

23,635 View
329 Download
5 Web of Science
6 Crossref

Abstract Summary PDF Supplementary Material

Abstract

OBJECTIVES
Diabetes is a well-known risk factor for atherosclerosis, but the association between a family history of diabetes and atherosclerosis remains unknown. In this study, we assessed the association between a family history of diabetes and increased carotid intima-media thickness (IMT), a marker of subclinical atherosclerosis, in a middle-aged Korean population.

METHODS

This cross-sectional study included 3,974 community-dwelling adults (1,404 male and 2,570 female) aged 30-64 years from the Cardiovascular and Metabolic Diseases Etiology Research Center cohort. The presence of a family history of diabetes was assessed through face-to-face interviews using a standardized questionnaire. Carotid IMT was assessed using B-mode ultrasonography, and increased IMT was defined as a value in the top quartile of the IMT values of all participants. Multivariate logistic regression was used to evaluate independent associations between a family history of diabetes and increased IMT.

RESULTS

A family history of diabetes was significantly associated with increased carotid IMT (odds ratio, 1.23; 95% confidence interval, 1.03 to 1.48) after adjusting for sex; age; body mass index; systolic blood pressure; total cholesterol, triglyceride, and hemoglobin A1c levels; smoking; alcohol consumption; exercise; use of antidiabetic, antihypertensive, and antilipidemic drugs; and a family history of hypertension. The positive association remained significant after excluding participants with diabetes (odds ratio, 1.21; 95% confidence interval, 1.00 to 1.47).

CONCLUSIONS

A family history of diabetes was positively associated with increased carotid IMT, even in participants without diabetes. Therefore, information on a family history of diabetes may help identify individuals at high risk of atherosclerotic cardiovascular disease.

Summary

Korean summary
한국의 30–64세 성인에게서 당뇨병 가족력이 있는 경우, 본인의 당뇨병 여부와 무관하게 경동맥 내중막 두께가 증가된 경향을 보였다. 이 결과는 당뇨병 가족력에 대한 정보를 파악하는 것은 죽상경화성 심혈관 질환의 위험이 높은 개인을 식별하는 데 도움이 될 수 있음을 시사한다.

Key Message
The family history of diabetes was positively associated with an increase in intima-media thickness of the carotid artery, even among people with normal fasting glucose levels. This suggests that asking for a family history of diabetes can help identify people at high risk of arteriosclerotic cardiovascular disease.

Citations

Citations to this article as recorded by

Endothelial cell phenotype is linked to endothelial dysfunction in individuals with a family history of type 2 diabetes
Noé Alvarado-Vásquez, Bettina Sommer, María Eva González-Trujano
Hormone Molecular Biology and Clinical Investigation.2025; 46(2): 85. CrossRef
Citropten Inhibits Vascular Smooth Muscle Cell Proliferation and Migration via the TRPV1 Receptor
Thi Hoa Pham, Nguyen Minh Trang, Eun-Nam Kim, Hye Gwang Jeong, Gil-Saeng Jeong
ACS Omega.2024; 9(27): 29829. CrossRef
Association between soft drink consumption and carotid atherosclerosis in a large-scale adult population: The TCLSIH cohort study
Ge Meng, Tongfeng Liu, Sabina Rayamajhi, Amrish Thapa, Shunming Zhang, Xuena Wang, Hongmei Wu, Yeqing Gu, Qing Zhang, Li Liu, Shaomei Sun, Xing Wang, Ming Zhou, Qiyu Jia, Kun Song, Zhongze Fang, Kaijun Niu
Nutrition, Metabolism and Cardiovascular Diseases.2023; 33(11): 2209. CrossRef
The association between grip strength and incident carotid atherosclerosis in middle-aged and older adults: The TCLSIH cohort study
Bei Zhang, Xuena Wang, Yeqing Gu, Qing Zhang, Li Liu, Ge Meng, Hongmei Wu, Shunming Zhang, Tingjing Zhang, Huiping Li, Juanjuan Zhang, Shaomei Sun, Xing Wang, Ming Zhou, Qiyu Jia, Kun Song, Jian Huang, Junsheng Huo, Bing Zhang, Gangqiang Ding, Kaijun Niu
Maturitas.2023; 167: 53. CrossRef
Clinical traits and systemic risks of familial diabetes mellitus according to age of onset and quantity: an analysis of data from the community-based KoGES cohort study
Ju-Yeun Lee, Kyungsik Kim, Sangjun Lee, Woo Ju An, Sue K. Park
Epidemiology and Health.2023; 45: e2023029. CrossRef
The Relationship between Family History of Diabetes and Diabetes by BMI and Age in Korean Men and Women
Eunna Ko, Jae Woong Sull
Biomedical Science Letters.2021; 27(4): 317. CrossRef

Trends in the prevalence and management of major metabolic risk factors for chronic disease over 20 years: findings from the 1998-2018 Korea National Health and Nutrition Examination Survey: Yoonjung Kim, Sun Jin Nho, Gyeongji Woo, Hyejin Kim, Suyeon Park, Youngtaek Kim, Ok Park, Kyungwon Oh; Epidemiol Health. 2021;43:e2021028. Published online April 19, 2021; DOI: https://doi.org/10.4178/epih.e2021028

31,418 View
428 Download
28 Web of Science
27 Crossref

Abstract Summary PDF Supplementary Material

Abstract

OBJECTIVES
We aimed to explore trends in the prevalence and management of obesity, hypertension, diabetes, and hypercholesterolemia in Korean adults from 1998 to 2018 using data from the Korea National Health and Nutrition Examination Survey (KNHANES).

METHODS

The study participants included 79,753 individuals aged ≥ 30 years who had participated in the health examination and health interview of the first (1998) to the seventh (2016-2018) KNHANES. The prevalence and management as well as annual percent change (APC) in chronic diseases were analyzed using SAS and the Joinpoint software program.

RESULTS

The prevalence of obesity in men significantly increased from 26.8% in 1998 to 44.7% in 2018 (APC= 1.9, p< 0.001), whereas that in women decreased slightly from 30.5% in 1998 to 28.3% in 2018 (APC= -0.5, p< 0.001). The prevalence of hypertension in men was 33.2% in 2018, with no significant change, whereas that in women slightly decreased to 23.1% in 2018 (APC= -0.9, p< 0.001). The prevalence of diabetes in men increased slightly from 10.5% in 2005 to 12.9% in 2018 (APC= 1.6, p< 0.001), whereas that in women remained at approximately 8%, with no significant change. The prevalence of hypercholesterolemia in both men and women increased 3-fold in 2018 (20.9% in men [APC = 8.2, p < 0.001] and 21.4% in women [APC= 7.1, p< 0.001]) compared to that in 2005. The awareness rate, treatment rate, and control rate of hypertension and hypercholesterolemia increased 2-3 fold. Regarding diabetes, the treatment rate increased, but the control rate did not change.

CONCLUSIONS

Over the past 20 years, the prevalence of obesity (in men), diabetes, and hypercholesterolemia has increased and management indicators, such as the awareness rate, treatment rate, and control rate of chronic diseases, have improved continuously.

Summary

Korean summary
국민건강영양조사(1998-2018) 자료를 활용하여 우리나라 성인의 비만, 고혈압, 당뇨병, 고콜레스테롤혈증 유병률 및 관리수준을 분석한 결과, 20년 동안 비만(남자), 당뇨병, 고콜레스테롤혈증 만성질환의 유병 수준은 악화되고 있는 반면, 만성질환의 인지율, 치료율, 치료자 중 조절률 등 관리지표는 지속적으로 개선되고 있었다.

Key Message
We examined trends in the prevalence and management of obesity, hypertension, diabetes, and hypercholesterolemia in Korean adults from the 1998-2018 Korea National Health and Nutrition Examination Survey. Over the past 20 years, the prevalence of obesity (in men), diabetes, and hypercholesterolemia has increased and management indicators, such as the awareness rate, treatment rate, and control rate of chronic diseases, have improved continuously.

Citations

Citations to this article as recorded by

Plan and operations of the 10th Korea National Health and Nutrition Examination Survey (2025–2027)
Sun-Ja Kim, Sihyun Park, Sunja Kim, Suyeon Park, Yoonjung Kim, Yunjung Choi, Sungha Yun, Kyungwon Oh
Epidemiology and Health.2026; 48: e2026001. CrossRef
Feasibility of a Structured Calorie-Restricted Dietary Intervention in Korean Adults with Early Type 2 Diabetes and Obesity: A Pilot Study
Su-Jeong Park, Mee Kyung Kim, Jinyoung Kim, Ji-Yeon Choi, YoonJu Song, Hyuk-Sang Kwon
Nutrients.2025; 17(9): 1530. CrossRef
The relationship between family conflict resolution methods and depressive symptoms in patients with chronic diseases
Min Jeong Joo, Jisu Ko, Jae Hyeok Lim, Dan Bi Kim, Eun-Cheol Park, Ali A. Weinstein
PLOS ONE.2025; 20(2): e0318378. CrossRef
Consultation time and communication patterns in outpatient care: an observational study in South Korea
Minjung Lee, Bumjo Oh, Myoungsoon You
BMC Health Services Research.2025;[Epub] CrossRef
The Standardized Prevalence Ratios of Occupational and Chronic Diseases Among Korean Firefighters Compared with the General Population
Soo Jin Kim, Seunghon Ham
Fire.2025; 8(10): 408. CrossRef
Cost-Effectiveness of a Mobile Health Program for Pre-elderly Adults
Eunmi Bae, Arum Moon, Seungju Baek, Jung-Ha Kim, Sunmee Jang
Journal of Medical Systems.2025;[Epub] CrossRef
Long-Term Cancer Incidence Trends in Korea (2001–2020): An Age–Period–Cohort and Joinpoint Analysis with a Focus on Younger Cohorts
Hyungho Lee, Mingyu Kim, Geehyun Song, Jae Young Joung, Hokyung Seo, Jin-Ha Yoon, Jinsoo Chung
Medicina.2025; 61(12): 2179. CrossRef
The role of glucagon-like peptide-1 receptor agonists (GLP1-RAs) in the management of the hypertensive patient with metabolic syndrome: a position paper from the Korean society of hypertension
Hae Young Lee, Seung-Hyun Ko, Sungjoon Park, Kyuho Kim, Song-Yi Kim, In-Jeong Cho, Eun Joo Cho, Hyeon Chang Kim, Jae-Hyeong Park, Sung Kee Ryu, Min Kyong Moon, Sang-Hyun Ihm
Clinical Hypertension.2024;[Epub] CrossRef
The Trend of Chronic Diseases Among Older Koreans, 2004–2020: Age–Period–Cohort Analysis
Eun Ha Namkung, Sung Hye Kang, Jessica A Kelley
The Journals of Gerontology, Series B: Psychological Sciences and Social Sciences.2024;[Epub] CrossRef
Health-Related Quality of Life and Associated Comorbidities in Community-Dwelling Women with Breast Cancer
Dong Kee Jang, Hyung Seok Nam, Jieun Kim, Yeo Hyung Kim
Journal of Clinical Medicine.2024; 13(17): 5321. CrossRef
Relationship Between the Risk of Obstructive Sleep Apnea and Cardiovascular Health in Middle-Aged Korean Men and Women: A Nationwide Study
Seo Young Kang, Jung Hwan Kim, Yunmi Kim
Journal of Clinical Medicine.2024; 13(22): 6702. CrossRef
Adherence to Cancer Prevention Guidelines and Cancer Incidence and Mortality: A Population-Based Cohort Study
Jin-Kyoung Oh, Minji Han, Byungmi Kim, Eun Young Park
Cancer Research and Treatment.2023; 55(1): 15. CrossRef
Deaths and disability-adjusted life years of hypertension in China, South Korea, and Japan: A trend over the past 29 years
Yan Qiu, Junzhuang Ma, Jiahong Zhu, Ying Liu, Wen Ren, Shuaishuai Zhang, Jingjing Ren
Frontiers in Cardiovascular Medicine.2023;[Epub] CrossRef
Lifestyle and dietary changes related to weight gain in college students during the COVID-19 pandemic
Jihyun Kim, Seunghee Kye
Journal of Nutrition and Health.2023; 56(3): 288. CrossRef
Ultra-Processed Food Consumption and Obesity in Korean Adults
Jee-Seon Shim, Kyoung Hwa Ha, Dae Jung Kim, Hyeon Chang Kim
Diabetes & Metabolism Journal.2023; 47(4): 547. CrossRef
Changes in metabolic syndrome and the risk of breast and endometrial cancer according to menopause in Korean women
Thi Xuan Mai Tran, Soyeoun Kim, Boyoung Park
Epidemiology and Health.2023; 45: e2023049. CrossRef
Diet quality partially mediates the association between ultraprocessed food consumption and adiposity indicators
Jee‐Seon Shim, Kyoung Hwa Ha, Dae Jung Kim, Hyeon Chang Kim
Obesity.2023; 31(9): 2430. CrossRef
Emulsion Stability and Antioxidant Analysis of Pinus koraiensis Leaves Salad Dressing for Lacto-Ovo Diets
Jin-Ju Baek, Soo-In Ryu, Jean Kyung Paik
Journal of the Korean Society of Food Science and Nutrition.2023; 52(10): 983. CrossRef
Changes in the management of hypertension, diabetes mellitus, and hypercholesterolemia in Korean adults before and during the COVID-19 pandemic: data from the 2010-2020 Korea National Health and Nutrition Examination Survey
Yoonjung Kim, Suyeon Park, Kyungwon Oh, Hongseok Choi, Eun Kyeong Jeong
Epidemiology and Health.2023; 45: e2023014. CrossRef
Korea hypertension fact sheet 2021: analysis of nationwide population-based data with special focus on hypertension in women
Hyeon Chang Kim, Hokyou Lee, Hyeok-Hee Lee, Eunsun Seo, Eunji Kim, Jiyen Han, Ja-Young Kwon
Clinical Hypertension.2022;[Epub] CrossRef
Sex-Specific Trends in the Prevalence of Hypertension and the Number of People With Hypertension: Analysis of the Korea National Health and Nutrition Examination Survey (KNHANES) 1998–2018
Eunsun Seo, Sunjae Jung, Hokyou Lee, Hyeon Chang Kim
Korean Circulation Journal.2022; 52(5): 382. CrossRef
Benefits of adherence to the Korea Healthy Eating Index on the risk factors and incidence of the metabolic syndrome: analysis of the 7th (2016–2018) Korea National Health and Nutrition Examination Survey
Sun A Choi, Sung Suk Chung, Jeong Ok Rho
Journal of Nutrition and Health.2022; 55(1): 120. CrossRef
Obesity, hypertension, diabetes mellitus, and hypercholesterolemia in Korean adults before and during the COVID-19 pandemic: a special report of the 2020 Korea National Health and Nutrition Examination Survey
Ga Bin Lee, Yoonjung Kim, Suyeon Park, Hyeon Chang Kim, Kyungwon Oh
Epidemiology and Health.2022; 44: e2022041. CrossRef
Current Status of the National Health Screening Programs in South Korea
Hee-Taik Kang
Korean Journal of Family Medicine.2022; 43(3): 168. CrossRef
Non-linear association between serum folate concentrations and dyslipidemia: Korea National Health and Nutrition Examination Survey 2016-2018
Taiyue Jin, Eun Young Park, Byungmi Kim, Jin-Kyoung Oh
Epidemiology and Health.2022; 44: e2022046. CrossRef
Prevalence and management of hypertension in Korean adults
Hyeon Chang Kim
Journal of the Korean Medical Association.2022; 65(10): 633. CrossRef
Effects of early medication treatment and metformin use for cancer prevention in diabetes patients: a nationwide sample cohort study in Korea using extended landmark time analysis
Hwa Jeong Seo, Hyun Sook Oh
Epidemiology and Health.2021; 43: e2021103. CrossRef

Diabetes and prediabetes prevalence among young and middle-aged adults in India, with an analysis of geographic differences: findings from the National Family Health Survey: Siddardha G. Chandrupatla, Isma Khalid, Tejdeep Muthuluri, Satyanarayana Dantala, Mary Tavares; Epidemiol Health. 2020;42:e2020065. Published online September 18, 2020; DOI: https://doi.org/10.4178/epih.e2020065

32,523 View
453 Download
23 Web of Science
20 Crossref

Abstract PDF

Abstract

OBJECTIVES
This study aimed to approximate the prevalence of hyperglycemia in India.

METHODS

The study was conducted using the Demographic and Health Survey 2015-16 (also known as the National Family Health Survey-4), which surveyed 811,808 individuals using a stratified, multistage, cluster sampling design. This cross-sectional survey recorded socio-demographic and anthropometric data, including blood glucose levels, of adults aged 18 years to 54 years.

RESULTS

The final analysis included 718,597 individuals, of whom 49.90% (weighted) were males. The overall prevalence of diabetes was 6.65% and that of prediabetes was 5.57%. A positive association was seen with urban residence, geographic region, sex, age, body mass index, socioeconomic status, and hypertension. Approximately two-thirds of individuals with diabetes lived in urban areas, and about half of the urban population was considered overweight/obese. South India showed a higher prevalence of diabetes (prevalence ratio, 2.01; p<0.001) than northern India.

CONCLUSIONS

Hyperglycemia (diabetes and prediabetes) has a high prevalence in India and is a major public health issue. Diabetes is unevenly distributed based on geographic location and urbanization. Prevention, early detection, and treatment strategies should consider this uneven distribution of diabetes.

Summary

Citations

Citations to this article as recorded by

Sedentary work and diabetes among individuals aged 15 years and older in India based on national family health survey 5
Kona Chandralekha, Jayanta Kumar Bora, Amrit Virk, Rajaram Yadav
Discover Public Health.2026;[Epub] CrossRef
Prevalence of hyperinsulinemia and its association with measures of adiposity and body composition in 16-25-year-old adolescents and young adults in Mumbai
Panchali Moitra, Jagmeet Madan, Soumik Kalita, Sharvari Desai, Shobha A. Udipi, Rama Vaidya
BMC Endocrine Disorders.2026;[Epub] CrossRef
The incremental value of aspartate aminotransferase/alanine aminotransferase ratio combined with CURB-65 in predicting treatment outcomes in hospitalized adult community-acquired pneumonia patients with type 2 diabetes mellitus
Huamei Zhou, Xuelei Zhu, Yi Zhang, Wenjuan Xu, Shiqun Li
BMC Pulmonary Medicine.2025;[Epub] CrossRef
Prevalence of diabetes and prediabetes in South Asian countries: a systematic review and meta-analysis
Masum Ali, Md Mahbub Alam, M. A. Rifat, Sonjida Mesket Simi, Sneha Sarwar, Md Ruhul Amin, Sanjib Saha
Discover Public Health.2025;[Epub] CrossRef
Monitoring Survey of Cancer Risk Factors and Health System Response in Northeast Region, Mizoram
Eric Zomawia, Sang Zuala, Evelyn V. L. Hmangaihzuali, Lalawmpuii Pachuau
Indian Journal of Public Health.2025; 69(4): 405. CrossRef
Therapeutic Fasting and Vitamin D Levels: A New Dimension in Type 2 Diabetes Mellitus Prevention and Management—A Brief Report
Pradeep M.K. Nair, Karishma Silwal, Prakash Babu Kodali, Gulab Rai Tewani
Journal of Health and Allied Sciences NU.2024; 14(04): 550. CrossRef
Charting Wellness in India: Piloting the iTHRIVE’s Functional Nutrition Approach to Improve Glycaemic and Inflammatory Parameters in Prediabetes and Type 2 Diabetes Mellitus
Mugdha Pradhan, Radhika Hedaoo, Anitta Joseph, Ria Jain
Cureus.2024;[Epub] CrossRef
Rural health dynamics: Exploring the prevalence of prediabetes and prehypertension among the rural population of Puducherry district
S Thamizhmaran, Madonna J Dsouza, Divyabharathy Ramadass, J Arun Daniel
Journal of Family Medicine and Primary Care.2024; 13(10): 4299. CrossRef
Platelet Indices: Predicting Retinopathy in Patients with Type 2 Diabetes Mellitus
Arijit Paul, Soumyadip Das, Koushik Bose, Rupam Karmakar
Medical Journal of Dr. D.Y. Patil Vidyapeeth.2024; 17(6): 1231. CrossRef
Impact of hypertension, diabetes, and obesity on quality of life in rural Punjab, India
Sapana Kasaudhan, Vineet Chaudhary, Kallur Nava Saraswathy, Rajinder Kumar Dhamija, K. S. S. Uma Mahesh, Naorem Kiranmala Devi
Discover Public Health.2024;[Epub] CrossRef
Diabetes Status among Adults in Rural India: Rural Noncommunicable Disease Clinic Observation
Sakshi Chaturvedi, Shagun Singh, Chakrapani Chaturvedi, Meenakshi Sharma, Shreenidhi Joshi, Anju Yadav, Kirti Chakerwarty
International Journal of Diabetes and Technology.2024; 3(4): 165. CrossRef
Gestational diabetes mellitus in early pregnancy amongst Asian Indian women: Evidence for poor pregnancy outcomes despite treatment
John Punnose, Rajeev Kumar Malhotra, Komal Sukhija, Rashika Rijhwani M, Naimaa Choudhary, Asha Sharma, Prassan Vij, Pinky Bahl
Diabetic Medicine.2023;[Epub] CrossRef
Diabetes mellitus early warning and factor analysis using ensemble Bayesian networks with SMOTE-ENN and Boruta
Xuchun Wang, Jiahui Ren, Hao Ren, Wenzhu Song, Yuchao Qiao, Ying Zhao, Liqin Linghu, Yu Cui, Zhiyang Zhao, Limin Chen, Lixia Qiu
Scientific Reports.2023;[Epub] CrossRef
Comparison of clinical characteristics and disease burden between early- and late-onset type 2 diabetes patients: a population-based cohort study
Mingqi Wang, Yifei He, Qiao He, Fusheng Di, Kang Zou, Wen Wang, Xin Sun
BMC Public Health.2023;[Epub] CrossRef
ANTHROPOLOGICAL AND BIOCHEMICAL METABOLIC FACTORS IN THE NORMOGLYCEMIC, PRE-DIABETIC, AND DIABETIC METABOLIC POPULATION
Jitender Sorout, Sudhanshu Kacker, Neha Saboo, Munesh Kumar
Eastern Ukrainian Medical Journal.2023; 11(4): 384. CrossRef
Socio-economic inequalities in diabetes and prediabetes among Bangladeshi adults
Abdur Razzaque Sarker, Moriam Khanam
Diabetology International.2022; 13(2): 421. CrossRef
Regional estimates of noncommunicable diseases associated risk factors among adults in India: results from National Noncommunicable Disease Monitoring Survey
Thilagavathi Ramamoorthy, Sravya Leburu, Vaitheeswaran Kulothungan, Prashant Mathur
BMC Public Health.2022;[Epub] CrossRef
Efficacy Analysis of Team-Based Nursing Compliance in Young and Middle-Aged Diabetes Mellitus Patients Based on Random Forest Algorithm and Logistic Regression
Dongni Qian, Hong Gao, Yao Chen
Computational and Mathematical Methods in Medicine.2022; 2022: 1. CrossRef
Factors Influencing Optimal Glucose Control among Type II Diabetes Patients: From the Health Behaviour Models’ Perspective
Eslavath Rajkumar, GT Kruthika, Padiri Angiel Ruth, R Lakshmi, Daniel Monica, John Romate, Abraham John
The Open Public Health Journal.2022;[Epub] CrossRef
Prevalence of prediabetes and associated factors of prediabetic stages: a cross-sectional study among adults in Nepal
Pushpanjali Shakya, Archana Shrestha, Biraj Man Karmacharya, Abha Shrestha, Bård Eirik Kulseng, Eva Skovlund, Abhijit Sen
BMJ Open.2022; 12(12): e064516. CrossRef

Trends in prediabetes and diabetes prevalence and associated risk factors in Vietnamese adults: That Thanh Ton, Anh Thi Ngoc Tran, Ich Thanh Do, Hoa Nguyen, Thi Thanh Binh Nguyen, Minh Tu Nguyen, Van Anh Bao Ha, Anh Quoc Tran, Huu Khoi Hoang, Binh Thang Tran; Epidemiol Health. 2020;42:e2020029. Published online May 11, 2020; DOI: https://doi.org/10.4178/epih.e2020029

37,793 View
396 Download
17 Web of Science
15 Crossref

Abstract PDF Supplementary Material

Abstract

OBJECTIVES
The prevalence of diabetes mellitus is rapidly increasing in Vietnam, particularly among adults aged over 45 years. This study estimated trends in diabetes and prediabetes prevalence and determined risk factors in Vietnamese adults (over 45 years).

METHODS

A cross-sectional study was conducted based on data from an annual diabetes screening program among people aged 45-69 years in an urban city in central Vietnam (Da Nang). Joinpoint regression analyses were performed to calculate the annual percentage change and ptrend-values. Multinomial logistic regression analysis was used to determine risk factors.

RESULTS

In total, 3,765 men and 9,149 women were included in this analysis. The age-adjusted prevalence of diabetes and prediabetes in 2017 was 11.4% and 52.9%, respectively. The prevalence of diabetes was higher in men (15.1%) than in women (10.3%), but that of prediabetes was similar in both genders (53.4% vs. 52.8%). The prevalence of prediabetes significantly increased during the study period, whereas no upward or downward trend for diabetes was observed. The prevalence of obesity, abdominal obesity, hypertension, and dyslipidemia showed no obvious trend. Obesity, a high waist-to-hip ratio, hypertension, more severe abdominal obesity, and dyslipidemia were significantly associated with a higher risk of diabetes and prediabetes.

CONCLUSIONS

Diabetes and prediabetes were more prevalent among people aged over 45 years than in the general population. Da Nang has experienced a marked increase in the prevalence of prediabetes. These findings have significant implications regarding the need for nationwide public health interventions and management aiming at diabetes prevention and control.

Summary

Citations

Citations to this article as recorded by

The burden of prediabetes in low- and middle-income countries: a systematic review and meta-analysis
Anjaly Joseph, Christian Sewor, Bhagiaswari Kodapally, Chanda Engred Manda, Jaison Joseph, Elezebeth Mathews
European Journal of Clinical Nutrition.2025; 79(9): 827. CrossRef
A Comparison of Emergency Room Visits and Hospital Admissions Between People with Prediabetes and Diabetes
Sharon Larson, Justin Beaupré, Stephanie Kjelstrom, Stanley Schwartz, William Hartz, Jackie Massuda
Population Health Management.2024; 27(4): 241. CrossRef
Risk factors for prediabetes in community‐dwelling adults: A generalized estimating equation logistic regression approach with natural language processing insights
Aeri Kim, Eunjoo Jeon, Hana Lee, Hyunsook Heo, Kyungmi Woo
Research in Nursing & Health.2024; 47(6): 620. CrossRef
Association of socioeconomic and lifestyle factors with prevalence of diabetes in rural southwest China: a structural equation modelling approach
Lan Liu, Xia Wu, Guo-Hui Li, Zi-Zi Yu, Du-Li Liu, Allison Rabkin Golden, Xiang-Yang Yin, Le Cai
BMJ Open.2024; 14(10): e086050. CrossRef
The Role of Screening, Risk Factors, and Early Intervention in Preventing Diabetes in the Obese Population: A Systematic Review
Noor A Merwass, Yazed K Alkhader, Salma A Alharthi, Rawdha M Al Fardan, Abdullah M Alqahtani, Fahad A Mahnashi, Nora M Salam, Mustafa M Al Najim, Ahmad A Alenezi , Abdullah O Binobaid
Cureus.2024;[Epub] CrossRef
Associations of intermediate hyperglycemia with elevated abdominal obesity, high-sensitivity C-reactive protein, and leptin in Korean adults
Heashoon Lee
Journal of Korean Biological Nursing Science.2024; 26(3): 250. CrossRef
Association of pre-diabetes with increased obesity and depression in older male and female: A secondary analysis of the Korea National Health and Nutrition Examination Survey 2020
Heashoon Lee
Journal of Korean Gerontological Nursing.2024; 26(3): 257. CrossRef
A single - center, retrospective observational study comparing the efficacy of empagliflozin and dapagliflozin as add-on therapy in type 2 diabetic patients
Nguyen Van Vy Hau, Nguyen Van Bang, Nguyen Thi Xuan, Pham Nguyen Tuyen Linh, Nguyen Thi Ngoc Thoi, Vo Thanh Trang, Phan Minh Trung, Le Van Chi, Nguyen Hai Thuy
Tạp chí Y học lâm sàng Bệnh viện Trung Ương Huế.2024; 16(8): 81. CrossRef
The prevalence of excess weight among Vietnamese adults: A pooled analysis of 58 studies with more 430 thousand participants over the last three decades
Tran Thai Phuc, Tran Quang Duc, Vu Thi Quynh Chi, Phan Ngoc Quang
Nutrition and Health.2023; 29(3): 443. CrossRef
Rural-urban differentials of prevalence and lifestyle determinants of pre-diabetes and diabetes among the elderly in southwest China
Yi Zhao, Hui-fang Li, Xia Wu, Guo-hui Li, Allison Rabkin Golden, Le Cai
BMC Public Health.2023;[Epub] CrossRef
Nonlinear relationship between atherogenic index of plasma and the risk of prediabetes: a retrospective study based on Chinese adults
Xiaodan Zheng, Xin Zhang, Yong Han, Haofei Hu, Changchun Cao
Cardiovascular Diabetology.2023;[Epub] CrossRef
Effectiveness of Textured Soybean Protein on Blood Biochemistry in Vietnamese Type 2 Diabetes Mellitus Patients
Ngoc Thi TA, Hien Thi Thu NGO, Phuong Mai NGUYEN, Thu Thi TRUONG, Giang Huong NGUYEN, Hang Thi Dieu DINH, Linh Thuy NGUYEN, Huong Thi LE, Khan Cong NGUYEN, Shigeru YAMAMOTO
Journal of Nutritional Science and Vitaminology.2022; 68(1): 32. CrossRef
Diabetes self-management and its associated factors among patients with diabetes in central Vietnam: A cross-sectional study
Van Bang Nguyen, Kim Huong Pham Thi, Thi Xuan Nguyen, Nguyen Tuyen Linh Pham, Van Vy Hau Nguyen, Chi Van Le, Muhammad Sajid Hamid Akash
PLOS ONE.2022; 17(7): e0270901. CrossRef
Prevalence of prediabetes and associated factors of prediabetic stages: a cross-sectional study among adults in Nepal
Pushpanjali Shakya, Archana Shrestha, Biraj Man Karmacharya, Abha Shrestha, Bård Eirik Kulseng, Eva Skovlund, Abhijit Sen
BMJ Open.2022; 12(12): e064516. CrossRef
Diabetes-Related Distress and Its Associated Factors Among Patients with Diabetes in Vietnam

Van Bang Nguyen, Tam Thi Tran, Thi Ly Dang, Van Vy Hau Nguyen, Binh Thang Tran, Chi Van Le, Nguyen Dinh Toan
Psychology Research and Behavior Management.2020; Volume 13: 1181. CrossRef

Lifestyle-related predictors affecting prediabetes and diabetes in 20-30-year-old young Korean adults: Kyong Sil Park, Seon Young Hwang; Epidemiol Health. 2020;42:e2020014. Published online March 19, 2020; DOI: https://doi.org/10.4178/epih.e2020014

28,355 View
330 Download
12 Web of Science
15 Crossref

Abstract Summary PDF Supplementary Material

Abstract

OBJECTIVES
To investigate lifestyle-related predictors of prediabetes and diabetes in young adults aged 20–39 years using data from the 2014-2016 Korea National Health and Nutrition Examination Survey (KNHANES).

METHODS

This study is a cross-sectional, secondary analysis using the KNHANES data. Participants were classified into normal group (fasting plasma glucose [FPG] <100 mg/dL and/or hemoglobin A1c [HbA1c] <5.7%), prediabetes group (FPG 100-125 mg/dL and/or HbA1c 5.7-6.4%), and diabetes group (FPG ≥126 mg/dL and/or HbA1c ≥ 6.5%). The data were statistically analyzed using SPSS software.

RESULTS

Out of 4,190 participants, 27.7% of men and 16.3% of women were in the prediabetes group and 1.4% of men and 1.3% of women were in the diabetes group. Logistic regression confirmed that age and obesity are predictors of prediabetes and diabetes in both men and women. Additionally low physical activity and low education level are predictors of prediabetes in men and women, respectively (p<0.05).

CONCLUSIONS

This study has found that age and increased obesity are predictors of elevated blood glucose in young men and women in their 20s and 30s. A strategy to lower obesity by promoting physical activity in men in their 30s is essential to prevent metabolic syndrome and progression to prediabetes.

Summary

Korean summary
20-30대 젊은 성인 남성에서 당뇨전단계 27.7%, 당뇨 1.4%, 여성에서 당뇨전단계 16.4%, 당뇨 1.3%로 확인되었다. 당뇨전단계 및 당뇨의 이환을 예방하기 위해서 비만 관리가 필수적이며, 특히 교육수준이 낮은 젊은 여성과 신체활동이 낮은 30대의 남성에서 신체활동 증진을 통해 효율적으로 비만도를 낮추는 전략 마련이 필요함을 확인하였다.

Citations

Citations to this article as recorded by

Determinants of Prediabetes in Adolescents: Evidence From Indonesia
Yourisna Pasambo, Ferry Efendi, Ika Yuni Widyawati, Rifky Octavia Pradipta, Fadhaa Aditya Kautsar Murti, Mei‐Chan Chong
Diabetes/Metabolism Research and Reviews.2026;[Epub] CrossRef
Association of healthy lifestyle and dietary practices with prediabetes among young Korean adults: sex-specific findings from KNHANES 2020–2024
Youngmi Lee, Sooyoun Kwon, Heejung Park, Jean Kyung Paik, Hee-Sook Lim, Yoo Kyoung Park, Yun-Jung Bae
Nutrition Research and Practice.2026; 20(3): 539. CrossRef
Impact of cumulative exposure to a high TG to HDL-C ratio on type 2 diabetes risk in young adults
Jung Heo, Byungpyo Kim, Kyungdo Han, Jae-Hyuk Lee, Seo-Young Sohn, Jiyeon Ahn, Whi-An Kwon, Moon Jung Kim, Eun-Young Doo, Min-Kyung Lee
Journal of Clinical Lipidology.2025; 19(2): 267. CrossRef
Role of oxidative stress in prediabetes development
Aarthi Yesupatham, Radha Saraswathy
Biochemistry and Biophysics Reports.2025; 43: 102069. CrossRef
Factors Affecting Hemoglobin A1c Level in Men and Women in Their 20s: Based on the Korean National Health and Nutrition Examination Survey 2022 to 2023
Deulle Min
Western Journal of Nursing Research.2025; 47(9): 826. CrossRef
Incidence and predictors of type 2 diabetes mellitus in a population-based cohort study in Abu Dhabi
Latifa Mohammad Baynouna AlKetbi, Rudina AlKetbi, Mariam Saif AlShamsi, Nico Nagelkerke, Bachar Afandi, Muna AlDobaee, Mariam AlKuwaiti, Mariam AlNeyadi, Ahmed Humaid, Noura AlAlawi, Hamda Aleissaee, Hanan Abdulbaqi, Toqa Fahmawee, Basil AlHashaikeh, AlYa
Scientific Reports.2025;[Epub] CrossRef
Prevalence and Risk Factors of Prediabetes in Indonesian Adults: A Cross-Sectional Study (2023)
Asti Elysia Rahmatul Fitri, Chandrayani Simanjorang, Laily Hanifah
Journal of Occupational Health and Epidemiology.2025; 14(3): 162. CrossRef
Effects of a Remote Physical Activity Improvement Program on Male Office Workers with Metabolic Syndrome in Their 30s and 40s with Sedentary Behavior: A Randomized Controlled Trial
Kyong Sil Park, Seon Young Hwang
Asian Nursing Research.2024; 18(2): 81. CrossRef
Relationship between Marriage and Prediabetes among Healthcare Workers: Mediating Effect of Triglycerides
Yong-Hsin Chen, Jia-June Lin, Hsiu-Mei Tang, Ching-Wen Yang, Gwo-Ping Jong, Yi-Sun Yang
Medicina.2024; 60(9): 1418. CrossRef
Prevalence of Impaired Fasting Glucose and Diabetes in Adults Aged 20-59 Years: Based on the 2012 and 2022 Korea National Health and Nutrition Examination Surveys
Suhee Kim, Ju-Yeon Uhm
Journal of Korean Public Health Nursing.2024; 38(3): 344. CrossRef
Prediabetes and all-cause mortality in young patients undergoing coronary artery angiography: a multicenter cohort study in China
Yibo He, Hongyu Lu, Yihang Ling, Jin Liu, Sijia Yu, Ziyou Zhou, Tian Chang, Yong Liu, Shiqun Chen, Jiyan Chen
Cardiovascular Diabetology.2023;[Epub] CrossRef
A Study Analyzing the Relationship among Impaired Fasting Glucose (IFG), Obesity Index, Physical Activity, and Beverage and Alcohol Consumption Frequency in 20s and 30s:The Korea National Health and Nutrition Examination Survey (KNHANES) 2013-2015
Yujin Lee, Jung-Hyun Kim
The Korean Journal of Community Living Science.2022; 33(1): 19. CrossRef
Sex differences in factors associated with prediabetes in Korean adults
Jin Suk Ra
Osong Public Health and Research Perspectives.2022; 13(2): 142. CrossRef
Differences in health behavior and nutrient intake status between diabetes-aware and unaware Korean adults based on the Korea national health and nutrition examination survey 2016–18 data: A cross-sectional study
Anshul Sharma, Chen Lulu, Kee-Ho Song, Hae-Jeung Lee
Frontiers in Public Health.2022;[Epub] CrossRef
Mediterranean Diet and Healthy Eating in Subjects with Prediabetes from the Mollerussa Prospective Observational Cohort Study
Mireia Falguera, Esmeralda Castelblanco, Marina Idalia Rojo-López, Maria Belén Vilanova, Jordi Real, Nuria Alcubierre, Neus Miró, Àngels Molló, Manel Mata-Cases, Josep Franch-Nadal, Minerva Granado-Casas, Didac Mauricio
Nutrients.2021; 13(1): 252. CrossRef

Trends in the prevalence and management of diabetes in Korea: 2007-2017: Ji-Yeon Shin; Epidemiol Health. 2019;41:e2019029. Published online July 4, 2019; DOI: https://doi.org/10.4178/epih.e2019029

35,959 View
346 Download
50 Web of Science
51 Crossref

Abstract Summary PDF Supplementary Material

Abstract

OBJECTIVES
This study analyzed Korea National Health and Nutrition Examination Survey data from 2007 to 2017 to assess trends in the prevalence, treatment, and control of diabetes in Korean adults ≥30 years of age.

METHODS

Prevalent diabetes was defined as a fasting plasma glucose level ≥126 mg/dL, self-reported use of anti-diabetic treatment (insulin or oral anti-diabetic drugs), or diabetes diagnosis by a physician. Target levels were defined as glycosylated hemoglobin <6.5% or <7.0%, blood pressure <130/80 mmHg, and total cholesterol <200 mg/dL. All survey waves were age-standardized to the 2005 Korean census population.

RESULTS

Diabetes prevalence increased from 9.6% in 2007-2009 to 10.8% in 2016-2017 (p<0.001). Impaired fasting glucose prevalence significantly increased in both genders and almost every age group. Diabetes awareness and glycemic control did not show an increasing trend; however, the treatment rate and proportion of people diagnosed with diabetes achieving target blood pressure and total cholesterol levels improved from 57.2% to 63.5% (p=0.008), from 41.1% to 53.2% (p<0.001), and from 65.0% to 78.0% (p<0.001), respectively.

CONCLUSIONS

From 2007 to 2017, the prevalence of diabetes increased moderately in Korea, whereas the diabetes treatment rate and the proportion of people diagnosed with diabetes achieving target blood pressure and total cholesterol levels improved. However, awareness of diabetes and glycemic control require significant improvements. A national-level action plan is required to raise awareness about diabetes and prediabetes, with the goal of improving glycemic control and minimizing the occurrence of adverse health outcomes.

Summary

Korean summary
지난 2007년-2017년 동안 우리나라 30세 이상 성인의 당뇨병 유병률은 소폭 증가하였으며, 당뇨환자의 치료율, 혈압 조절율, 총콜레스테롤 조절율은 증가 추세를 보였다. 그러나 당뇨병 인지율과 당뇨 환자의 혈당 조절율은 현재의 추세대로라면 Health Plan 2020의 목표치를 달성하기 어려울 것으로 보이며, 개선이 필요하다.

Citations

Citations to this article as recorded by

Age-stratified comorbidity transitions and interconnected mapping of nine allergic diseases
Ju Hee Kim, Eun Lee, Jeewon Shin, Eunkyo Ha, Hana Yoo, Soonchul Lee, Man Yong Han
Allergology International.2026; 75(2): 252. CrossRef
TRATAMENTO E CONTROLE DO DIABETES MELLITUS NA ATENÇÃO PRIMÁRIA À SAÚDE EM RIO BRANCO, ACRE
Aline Fernanda Silva Sampaio, Thatiana Lameira Maciel Amaral , Cledir de Araújo Amaral, Mauricio Teixeira Leite de Vasconcellos, Gina Torres Rego Monteiro
Revista Contemporânea.2026; 6(1): e10156. CrossRef
Risk of obstructive sleep apnea and diabetes in Korean adults
Mi Ah Han
Endocrine Research.2026; 51(2): 93. CrossRef
Impact of Dietary Supplement Usage on Nutrient Adequacy and the Risk of Nutrient Excess Among Korean Adults
Seongha Kim, Jihee Shin, Yoonmi Park, Kwang Suk Ko, Hye Mi Kim, Chaewon Lee, Soohan Jung, Seok‐Hee Lee, Yooheon Park, Huiwon Seo, Ga‐Hee Shin, Sangmin Lee, Byeongchul Kang, Seungyoun Jung
Journal of Human Nutrition and Dietetics.2026;[Epub] CrossRef
Trends of diabetes in Beijing, China
Aijuan Ma, Jun Lyu, Zhong Dong, Li Nie, Chen Xie, Bo Jiang, Xueyu Han, Jing Dong, Yue Zhao, Liming Li
Chinese Medical Journal.2025; 138(6): 713. CrossRef
Non-linear relationship between arteriosclerosis index and diabetes risk in non-obese east Asian adults
Jun Cao, Jitong Liu, Ke Yu, Zhenhua Huang, Shunrong Lv, Wenfei Zeng
Scientific Reports.2025;[Epub] CrossRef
The Cascade of Care for Diabetes and Risks of Functional Limitation — China, 2011–2020
Yihao Zhao, Ziyang Ren, Panliang Zhong, Yugang Li, Ruitai Shao, Xiaoying Zheng, Enying Gong, Zhiqiang Song
China CDC Weekly.2025; 7(15): 503. CrossRef
Prevalence of cardiovascular-kidney-metabolic syndrome in Korea: Korea National Health and Nutrition Examination Survey 2011-2021
Sung-Bin Hong, Ji-Eun Kim, Seung Seok Han, Joseph J. Shearer, Jungnam Joo, Ji-Yeob Choi, Véronique L. Roger
Epidemiology and Health.2025; 47: e2025005. CrossRef
From Plants to Protection: Cardiorenal Benefits in Non-Diabetic Chronic Kidney Disease and Heart Failure
Dan Claudiu Măgureanu, Raluca Maria Pop, Ioana Corina Bocsan, Maria Adriana Neag, Angela Cozma, Antonia Mihaela Levai, Veronica Sanda Chedea, Anca Dana Buzoianu
Molecules.2025; 30(19): 3982. CrossRef
Intersection of Gender-Race/Color and Glycemic Control in Diabetes in Nine Years of Follow-up of the ELSA-Brazil Cohort
Gisseila Andrea Ferreira Garcia, Luana Giatti, Lidiane V. Camelo, Maria de Fátima Sander, Rosane Harter Griep, Maria de Jesus Mendes da Fonseca, Maria Inês Schmidt, Sandhi Maria Barreto
Journal of Racial and Ethnic Health Disparities.2025;[Epub] CrossRef
Glycemic outcomes of people with diabetes mellitus in Brazilian primary health care
Adrielen Aparecida Silva Calixto, Laercio Joel Franco, Rebecca Ortiz La Banca Barber, Luis Angel Cendejas Medina, Maria Tereza Gonçalves Torquato, Marta Maria Coelho Damasceno, Maria Lúcia Zanetti, Carla Regina de Souza Teixeira
International Journal of Diabetes in Developing Countries.2024; 44(1): 91. CrossRef
Sex differences in the reciprocal relationship between glycemic control and depressive symptoms among older adults with diabetes: Using a nationwide population‐based sample
Gyeong A Kang, Chang Won Won, Miji Kim, Ju Young Yoon
Geriatrics & Gerontology International.2024; 24(1): 32. CrossRef
SCORE and SCORE2 in East Asian Population
JungMin Choi, Soseul Sung, Sue K. Park, Seyong Park, Hyoyeong Kim, Myeong-Chan Cho, Bryan Williams, Hae-Young Lee
JACC: Asia.2024; 4(4): 265. CrossRef
Prevalence and outcomes of chronic comorbid conditions in patients with sepsis in Korea: a nationwide cohort study from 2011 to 2016
Christine Kang, Seongmi Choi, Eun Jin Jang, Somin Joo, Jae Hoon Jeong, Seung-Young Oh, Ho Geol Ryu, Hannah Lee
BMC Infectious Diseases.2024;[Epub] CrossRef
Incidence rates of retinal vascular occlusive diseases from 2011 to 2020 in South Korea: a nationwide cohort study
Shin Hyeong Park, Bum Jun Kim, Ji Hye Kim, Seung Chan Kim, Rock Bum Kim, Yong Seop Han
BMC Ophthalmology.2024;[Epub] CrossRef
Lowering Barriers to Health Risk Assessments in Promoting Personalized Health Management
Hayoung Park, Se Young Jung, Min Kyu Han, Yeonhoon Jang, Yeo Rae Moon, Taewook Kim, Soo-Yong Shin, Hee Hwang
Journal of Personalized Medicine.2024; 14(3): 316. CrossRef
Variations in health-related quality of life (EQ-5D) associated with cardiovascular health: a cross-sectional study of adults with diabetes in the Korean general population
Hyejin Jung
BMJ Open.2024; 14(5): e081789. CrossRef
Homocysteine levels are associated with diabetes mellitus in Chinese with H-type hypertension
Dejian Fu, Wanbao Gong, Xiaomin Bao, Bo Yang, Feng Wang, Yubing Qiao, Yuanjiang Wu, Guangzhen Chen, Weixun Sun, Qiongzhi Xiao, Wenbo Zou, Ning Fang
Nutrition Research and Practice.2024; 18(4): 511. CrossRef
The KL genetic polymorphisms Associated with type 2 diabetes Mellitus
Hyun-Seok Jin, Dongju Jung
Indian Journal of Clinical Biochemistry.2023; 38(3): 385. CrossRef
Fatty Liver and Risk of Head and Neck Cancer in Type 2 Diabetes Mellitus: A Nationwide Cohort Study
Junhee Park, Kyungdo Han, Seung Woo Lee, Yeong Jeong Jeon, Sang-Man Jin, Wonyoung Jung, Yoon Kyoung So, Sang Duk Hong, Dong Wook Shin
Cancers.2023; 15(4): 1209. CrossRef
Type 2 Diabetes Mellitus- and Complication-Related Risk of Nontuberculous Mycobacterial Disease in a South Korean Cohort
Da Som Jeon, Seonok Kim, Mi Ae Kim, Yong Pil Chong, Tae Sun Shim, Chang Hee Jung, Ye-Jee Kim, Kyung-Wook Jo, Paschalis Vergidis, Byung Woo Jhun
Microbiology Spectrum.2023;[Epub] CrossRef
Association between breakfast frequency and insulin resistance in Korean adults with prediabetes: A nationwide population-based cross-sectional study
Sihyung Lee, Duk Chul Lee, Hye Jun Lee
Diabetes & Metabolic Syndrome: Clinical Research & Reviews.2023; 17(4): 102763. CrossRef
Trends in Frailty Prevalence Among Older Adults in Korea: A Nationwide Study From 2008 to 2020
Min-gu Kang, Oh Seok Kim, Emiel O. Hoogendijk, Hee-Won Jung
Journal of Korean Medical Science.2023;[Epub] CrossRef
Clinical traits and systemic risks of familial diabetes mellitus according to age of onset and quantity: an analysis of data from the community-based KoGES cohort study
Ju-Yeun Lee, Kyungsik Kim, Sangjun Lee, Woo Ju An, Sue K. Park
Epidemiology and Health.2023; 45: e2023029. CrossRef
Prevalence trends and disease burden of diabetes and prediabetes in Chinese adults of Shanghai
Jianfeng Pei, Yanyun Li, Yihui Yang, Minna Cheng, Yan Shi, Wang Hong Xu
Journal of Diabetes.2023; 15(7): 583. CrossRef
Incidence and temporal trends in type 2 diabetes by weight status: A systematic review and meta-analysis of prospective cohort studies
Hong-jie Yu, Mandy Ho, Xiangxiang Liu, Jundi Yang, Pui Hing Chau, Daniel Yee Tak Fong
Journal of Global Health.2023;[Epub] CrossRef
Amplitude of Low-Frequency Fluctuation to Determine Disturbed Spontaneous Brain-Activity Pattern in Patients with Diabetic Optic Neuropathy
Xiao-Yu Wang, San-Hua Xu, Hong Wei, Min Kang, Jie Zou, Qian Ling, Hui Huang, Xu Chen, Yi-Xin Wang, Yi Shao, Yao Yu
Diabetes, Metabolic Syndrome and Obesity.2023; Volume 16: 2899. CrossRef
Non-Alcoholic Fatty Liver Disease and the Risk of Diabetes Mellitus by Menopausal Status: A Nationwide Cohort Study
Jungeun Shin, Soo Jung Choi, Han Rim Lee, Kyungdo Han, Jiwon Chang, Su-Min Jeong, Yun-sun Choi, Daeho Lee, Dong Wook Shin
Journal of Personalized Medicine.2022; 12(4): 546. CrossRef
High prevalence of diabetes in elderly of Iran: an urgent public health issue
Farid Fotouhi, Farhad Rezvan, Hassan Hashemi, Ali Javaherforoushzadeh, Mirgholamreza Mahbod, Abbasali Yekta, Zahra Jamshididana, Mehdi Khabazkhoob
Journal of Diabetes & Metabolic Disorders.2022; 21(1): 777. CrossRef
Annual Trends in the Incidence and Prevalence of Alzheimer's Disease in South Korea: A Nationwide Cohort Study
Min Seok Baek, Han-Kyeol Kim, Kyungdo Han, Hyuk-Sung Kwon, Han Kyu Na, Chul Hyoung Lyoo, Hanna Cho
Frontiers in Neurology.2022;[Epub] CrossRef
Current Status of the National Health Screening Programs in South Korea
Hee-Taik Kang
Korean Journal of Family Medicine.2022; 43(3): 168. CrossRef
Time trend of diabetes mellitus in adults and elderly people in Rio Branco, Acre, Western Brazilian Amazon (2006–2020)
Yara de Moura Magalhães Lima, Fernanda Andrade Martins, Alanderson Alves Ramalho
Diabetes Epidemiology and Management.2022; 7: 100093. CrossRef
Burden, trends, and risk factors for breast cancer in China from 1990 to 2019 and its predictions until 2034: an up-to-date overview and comparison with those in Japan and South Korea
Na Liu, Da-Wei Yang, Yan-Xia Wu, Wen-Qiong Xue, Dan-Hua Li, Jiang-Bo Zhang, Yong-Qiao He, Wei-Hua Jia
BMC Cancer.2022;[Epub] CrossRef
Differences in health behavior and nutrient intake status between diabetes-aware and unaware Korean adults based on the Korea national health and nutrition examination survey 2016–18 data: A cross-sectional study
Anshul Sharma, Chen Lulu, Kee-Ho Song, Hae-Jeung Lee
Frontiers in Public Health.2022;[Epub] CrossRef
Fasting blood glucose and risk of incident pancreatic cancer
Young Jin Kim, Chang-Mo Oh, Sung Keun Park, Ju Young Jung, Min-Ho Kim, Eunhee Ha, Do Jin Nam, Yeji Kim, Eun Hye Yang, Hyo Choon Lee, Soon Su Shin, Jae-Hong Ryoo, Altaf Mohammed
PLOS ONE.2022; 17(10): e0274195. CrossRef
Effects of Diabetes Quality Assessment on Diabetes Management Behaviors Based on a Nationwide Survey
Chang Kyun Choi, Jungho Yang, Ji-An Jeong, Min-Ho Shin
International Journal of Environmental Research and Public Health.2022; 19(23): 15781. CrossRef
Estimating the disease burden of Korean type 2 diabetes mellitus patients considering its complications
Juyoung Kim, Seok-Jun Yoon, Min-Woo Jo, Brecht Devleesschauwer
PLOS ONE.2021; 16(2): e0246635. CrossRef
Assessment of Trends in the Incidence Rates of Central Retinal Artery Occlusion in Korea From 2002 to 2015
Jongshin Kim, Seong Jun Byun, Se Joon Woo, Kyu Hyung Park, Sang Jun Park
JAMA Ophthalmology.2021; 139(4): 399. CrossRef
Trends of Diabetes and Prediabetes Prevalence among Korean Adolescents From 2007 to 2018
Ji Hyun Kim, Jung Sub Lim
Journal of Korean Medical Science.2021;[Epub] CrossRef
Prevalence and risk factors of diabetes among adults aged 45 years or older in China: A national cross‐sectional study
Anying Bai, Jing Tao, Liyuan Tao, Jue Liu
Endocrinology, Diabetes & Metabolism.2021;[Epub] CrossRef
Comorbidity network analysis related to obesity in middle-aged and older adults: findings from Korean population-based survey data
Hye Ah Lee, Hyesook Park
Epidemiology and Health.2021; 43: e2021018. CrossRef
Association between domain-specific physical activity and diabetes in Korean adults
Eun-Byeol Lee, Sunghyun Hong, Jihee Min, Dong-Hyuk Park, Wonhee Cho, Sang-Hoon Suh, Hae-Dong Lee, Han-Joo Lee, Heejin Kimm, Sun Ha Jee, Eun Seok Kang, Dong Hoon Lee, Justin Y. Jeon
Scientific Reports.2021;[Epub] CrossRef
The Current Situation Regarding Long-Acting Insulin Analogues Including Biosimilars Among African, Asian, European, and South American Countries; Findings and Implications for the Future
Brian Godman, Mainul Haque, Trudy Leong, Eleonora Allocati, Santosh Kumar, Salequl Islam, Jaykaran Charan, Farhana Akter, Amanj Kurdi, Carlos Vassalo, Muhammed Abu Bakar, Sagir Abdur Rahim, Nusrat Sultana, Farzana Deeba, M. A. Halim Khan, A. B. M. Muksudu
Frontiers in Public Health.2021;[Epub] CrossRef
Current utilization patterns for long-acting insulin analogues including biosimilars among selected Asian countries and the implications for the future
Brian Godman, Mainul Haque, Santosh Kumar, Salequl Islam, Jaykaran Charan, Farhana Akter, Amanj Kurdi, Eleonora Allocati, Muhammed Abu Bakar, Sagir Abdur Rahim, Nusrat Sultana, Farzana Deeba, M. A. Halim Khan, A. B. M Muksudul Alam, Iffat Jahan, Zubair Ma
Current Medical Research and Opinion.2021; 37(9): 1529. CrossRef
Trends in the prevalence and management of major metabolic risk factors for chronic disease over 20 years: findings from the 1998-2018 Korea National Health and Nutrition Examination Survey
Yoonjung Kim, Sun Jin Nho, Gyeongji Woo, Hyejin Kim, Suyeon Park, Youngtaek Kim, Ok Park, Kyungwon Oh
Epidemiology and Health.2021; 43: e2021028. CrossRef
Dietary carbohydrates interact with AMY1 polymorphisms to influence the incidence of type 2 diabetes in Korean adults
Dayeon Shin, Kyung Won Lee
Scientific Reports.2021;[Epub] CrossRef
Clinical Characteristics and Associated Risk Factors of Prediabetes in the Southwestern Region of Korea from 2010–2019
Mi-Ra Oh, Su-Jin Jung, Eun-Ju Bae, Byung-Hyun Park, Soo-Wan Chae
Journal of Clinical Medicine.2020; 9(4): 1114. CrossRef
Interactions of Habitual Coffee Consumption by Genetic Polymorphisms with the Risk of Prediabetes and Type 2 Diabetes Combined
Taiyue Jin, Jiyoung Youn, An Na Kim, Moonil Kang, Kyunga Kim, Joohon Sung, Jung Eun Lee
Nutrients.2020; 12(8): 2228. CrossRef
Anemia and incidence of dementia in patients with new-onset type 2 diabetes: a nationwide population-based cohort study
Jae Woo Choi, Tae Hyun Kim, Euna Han
BMJ Open Diabetes Research & Care.2020; 8(1): e001289. CrossRef
Body Weight Variability and the Risk of Cardiovascular Outcomes and Mortality in Patients With Type 2 Diabetes: A Nationwide Cohort Study
Ga Eun Nam, Wonsock Kim, Kyungdo Han, Chung-woo Lee, Yeongkeun Kwon, Byoungduck Han, Seokwon Park, Joo-Hyun Park, Yang-Hyun Kim, Do-Hoon Kim, Seon Mee Kim, Youn Seon Choi, Kyung Hwan Cho, Yong Gyu Park
Diabetes Care.2020; 43(9): 2234. CrossRef
Association of Blood Cadmium with Cardiovascular Disease in Korea: From the Korea National Health and Nutrition Examination Survey 2008–2013 and 2016
Jihyun Jeong, Sang-moon Yun, Minkyeong Kim, Young Ho Koh
International Journal of Environmental Research and Public Health.2020; 17(17): 6288. CrossRef

Pre-hypertension and the risk of diabetes mellitus incidence using a marginal structural model in an Iranian prospective cohort study: Ahmad Khosravi, Mohammad Hassan Emamian, Hassan Hashemi, Akbar Fotouhi; Epidemiol Health. 2018;40:e2018026. Published online June 23, 2018; DOI: https://doi.org/10.4178/epih.e2018026

25,255 View
200 Download
7 Web of Science
6 Crossref

Abstract PDF

Abstract

OBJECTIVES
The aim of this study was to evaluate the effect of pre-hypertension and its sub-classification on the development of diabetes.

METHODS

In this cohort study, 2,941 people 40 to 64 years old without hypertension or diabetes were followed from 2009 through 2014. According to the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC)-7 criteria, we classified participants into normal and pre-hypertension groups. The effect of pre-hypertension on the 5-year incidence rate of diabetes was studied using inverse probability of treatment weighting. We modeled the exposure and censored cases given confounding factors such as age, sex, body mass index, smoking, economic status, and education.

RESULTS

The 5-year incidence rate of diabetes among people with pre-hypertension and those with normal blood pressure (BP) was 12.7 and 9.7%, respectively. The risk ratio (RR) for people with pre-hypertension was estimated to be 1.13 (95% confidence interval [CI], 0.90 to 1.41). The RRs among people with normal BP and high-normal BP, according to the JNC-6 criteria, compared to those with optimal BP were 0.96 (95% CI, 0.73 to 1.25) and 1.31 (95% CI, 1.01 to 1.72), respectively.

CONCLUSIONS

Our results showed that participants who had higher levels of BP (high-normal compared to optimal BP) had a higher risk of diabetes development. With regard to the quantitative nature of BP, using the specifically distinguishing of stage 1 hypertension or high-normal BP may be a more meaningful categorization for diabetes risk assessment than the JNC-7 classification.

Summary

Citations

Citations to this article as recorded by

The difference between cystatin C- and creatinine-based estimated glomerular filtration rate and risk of hypertension: a population-based study in middle-aged and elderly Chinese
Junxi Liu, Yanjia Li, Xuwen Yi, Xue Wang, Boda Zhou
The Journal of Cardiovascular Aging.2025;[Epub] CrossRef
The association of ALT to HDL-C ratio with type 2 diabetes in 50–74 years old adults: a population-based study
Abolfazl Emamian, Mohammad Hassan Emamian, Hassan Hashemi, Akbar Fotouhi
Scientific Reports.2024;[Epub] CrossRef
Prevalence of prediabetes, diabetes, diabetes awareness, treatment, and its socioeconomic inequality in west of Iran
Farhad Moradpour, Satar Rezaei, Bakhtiar Piroozi, Ghobad Moradi, Yousef Moradi, Negar Piri, Azad Shokri
Scientific Reports.2022;[Epub] CrossRef
Association between cardiovascular risk factors and stage 1 hypertension defined by the 2017 ACC/AHA guidelines
Xing Zhen Liu, Dong Shui Chen, Fu Ping Di, Cheng Yong Shi, Hui Hua Li, Jun Min Wang, Yi Xin Ji
Clinical and Experimental Hypertension.2020; 42(6): 483. CrossRef
Obesity is the Most Important Factor for Gender Inequality in Type 2 Diabetes Incidence in an Iranian Population
Ahamd Khosravi, Mohammad Hassan Hashemian, Hassan Hashemi, Akbar Fotouhi
International Journal of Preventive Medicine.2019;[Epub] CrossRef
Blood Pressure and the Risk of Death From Non-cardiovascular Diseases: A Population-based Cohort Study of Korean Adults
Jeoungbin Choi, Jieun Jang, Yoonsuk An, Sue K. Park
Journal of Preventive Medicine and Public Health.2018; 51(6): 298. CrossRef

Cancer screening rate in people with diabetes in the Korean population: results from the Korea National Health and Nutrition Examination Survey 2007-2009: Kumban Walter Chuck, Minji Hwang, Kui Son Choi, Mina Suh, Jae Kwan Jun, Boyoung Park; Epidemiol Health. 2017;39:e2017036. Published online August 10, 2017; DOI: https://doi.org/10.4178/epih.e2017036

27,285 View
270 Download
20 Web of Science
23 Crossref

Abstract Summary PDF

Abstract

OBJECTIVES
To investigate the screening rates for gastric, breast, and cervical cancer in people with diabetes compared with people without diabetes.

METHODS

Data from the Korea National Health and Nutrition Examination Survey (2007-2009) were used. Cancer-free men who were 40 years old and over and cancer-free women who were 30 years old and over were included. The lifetime screening rate and regular screening rate were compared in people with and without diabetes.

RESULTS

Fewer people with diabetes than people without diabetes had ever received cancer screening (53.5 vs. 59.5%, p<0.001 for gastric cancer; 60.5 vs. 71.5%, p<0.001 for breast cancer; and 49.1 vs. 59.6%, p<0.001 for cervical cancer). Fewer people with diabetes than people without diabetes received the recommended screenings for gastric cancer (38.9 vs. 42.9%, p<0.001), breast cancer (38.8 vs. 44.6%, p<0.001), and cervical cancer (35.1 vs. 51.2%, p<0.001). In subgroup analyses according to socioeconomic factors, the lifetime and recommended screening rates were lower in the diabetic population in most socioeconomic subgroups. In the multivariate analysis adjusted for socioeconomic factors, people with diabetes showed lower lifetime screening rates for gastric and cervical cancer (odds ratio [OR], 0.8; 95% confidence interval [CI], 0.7 to 0.9 and OR, 0.7; 95% CI, 0.6 to 0.9), and lower regular screening rates for breast and cervical cancer (OR, 0.7; 95% CI, 0.6 to 0.9 and OR, 0.7; 95% CI, 0.5 to 0.9).

CONCLUSIONS

The cancer screening rate in people with diabetes was lower than in people without diabetes. Considering the higher cancer risk in people with diabetes, efforts to increase the screening rate in this high-risk population should be implemented.

Summary

Korean summary
기존의 여러 연구에서 당뇨병이 있는 사람에서 당뇨병이 없는 경우에 비해 암 발생의 위험이 증가하는 것이 확인되었다. 본 연구에서 당뇨병이 있는 사람과 없는 사람에서 암 수검률을 비교했을 때, 당뇨병이 있는 사람의 위암, 유방암, 자궁경부암의 평생 수검률과 권고안 이행 수검률은 모두 낮았다. 당뇨병 환자가 암 발생의 고위험군임을 고려하였을 때 이들을 대상으로 암 검진 수검률을 높이려는 노력이 필요하다.

Citations

Citations to this article as recorded by

Leveraging Sight Outcomes Research Collaborative (SOURCE) Data to Predict Initial Presentation With Advanced Open-Angle Glaucoma
RITHAMBARA RAMACHANDRAN, AARON T. ZHAO, YINXI YU, PAULA ANNE NEWMAN-CASEY, JOSHUA D. STEIN
American Journal of Ophthalmology.2026; 281: 297. CrossRef
Preventive Health Services in Reproductive-Aged Women with Diabetes Mellitus: A Scoping Review
Madeline L. Treasure, Pourandokht S. Nourbakhsh, Kate Diaz Roldan, Antonia Osuna-Garcia, Sara C. Esteves, Lisa N. Kransdorf, Lauren E. Wisk
Journal of General Internal Medicine.2026;[Epub] CrossRef
Skin autofluorescence of advanced glycation end-products, glycemic memory, and diabetes complications
Vincent Rigalleau, Yann Pucheux, Thierry Couffinhal, Frederic J Tessier, Michael Howsam, Sébastien Rubin, Catherine Helmer, Fadi Alkhami, Alice Larroumet, Laurence Blanco, Marie-Amélie Barbet-Massin, Amandine Ferriere, Kamel Mohammedi, Ninon Foussard
Diabetes & Metabolism.2025; 51(1): 101600. CrossRef
Association Between Suicidal Ideation and Cancer Screening Uptake: Results from Middle-Aged and Older Adults in Korea
Seong-Uk Baek, Jin-Ha Yoon
Cancers.2025; 17(6): 956. CrossRef
Typ-2-Diabetes mellitus und gastrointestinale Krebsvorsorge
Hans Scherübl
Diabetologie und Stoffwechsel.2025; 20(06): 441. CrossRef
Cancer Screening Behavior among People Living with HIV: A Cross-sectional Study at an AIDS Core Hospital in Tokyo, Japan
Haruka Tsuda, Michiko Koga, Kazuhiko Ikeuchi, Makoto Saito, Eisuke Adachi, Tadashi Kikuchi, Takeya Tsutsumi, Hiroshi Yotsuyanagi
Health Evaluation and Promotion.2024; 51(4): 377. CrossRef
Exploring the Interplay of Diabetes, Deaf Patient Reported Outcomes, and Cancer Screening in Deaf and Hard of Hearing Women
Emmanuel Perrodin-Njoku, Sowmya Rao, Regina Wang, Christopher Moreland, Poorna Kushalnagar
International Journal of Women's Health.2024; Volume 16: 1235. CrossRef
Association Between Type 1 Diabetes Mellitus and Incident Gastrointestinal Cancer in Korean Population: A Nationwide Retrospective Cohort Study
Soonsu Shin, Min‐Ho Kim, Chang‐Mo Oh, Eunhee Ha, Jae‐Hong Ryoo
Diabetes/Metabolism Research and Reviews.2024;[Epub] CrossRef
Typ-2-Diabetes mellitus und gastrointestinale Krebsvorsorge
Hans Scherübl
Zeitschrift für Gastroenterologie.2023; 61(06): 683. CrossRef
Increased Breast and Colorectal Cancer Risk in Type 2 Diabetes: Awareness Among Adults With and Without Diabetes and Information Provision on Diabetes Websites
Laura Ashley, Kathryn A Robb, Daryl B O’Connor, Rebecca Platt, Mollie Price, Olivia Robinson, Elizabeth Travis, Lorraine Lipscombe, Ramzi Ajjan, Rebecca Birch
Annals of Behavioral Medicine.2023; 57(5): 386. CrossRef
Diabetes and Cancer
Jae Won Hong
The Journal of Korean Diabetes.2023; 24(1): 12. CrossRef
Diabetes mellitus and cancer
Jae Won Hong
Cardiovascular Prevention and Pharmacotherapy.2023; 5(3): 69. CrossRef
More new cancers in type 2 diabetes with diabetic foot disease: A longitudinal observational study
Fadi Alkhami, Gauthier Borderie, Ninon Foussard, Alice Larroumet, Laurence Blanco, Marie-Amélie Barbet-Massin, Amandine Ferrière, Claire Ducos, Frédéric Domenge, Kamel Mohammedi, Vincent Rigalleau
Diabetes & Metabolic Syndrome: Clinical Research & Reviews.2023; 17(10): 102859. CrossRef
Do diabetic complications influence cancer-related events in people with type 2 diabetes? A cohort approach
Evelyne Liuu, Pierre-Jean Saulnier, Elise Gand, Gautier Defossez, Amélie Jamet, Stéphanie Ragot, Marc Paccalin, Samy Hadjadj
Diabetes & Metabolism.2022; 48(2): 101289. CrossRef
Factors associated with adherence to colonoscopy among individuals who were positive in the preliminary screening for colorectal neoplasms
Ji‐Bin Li, Keng‐Jian Ke, Wei‐Li Zhang, Ling‐Yan Wang, Yan‐Ping Wu, Fan Weng, Huan Tian, Zhi‐Yu Qiu, Yin Li, Shi‐Yong Lin, Mei‐Xian Ye, Qing‐Jian Ou, Cheng‐Hua Gong, Zhen‐Hai Lu, Zhi‐Zhong Pan, De‐Sen Wan, Jian‐Hong Peng, Yu‐Jing Fang
Cancer Medicine.2022; 11(22): 4321. CrossRef
Prediction Model for Hypertension and Diabetes Mellitus Using Korean Public Health Examination Data (2002–2017)
Yong Whi Jeong, Yeojin Jung, Hoyeon Jeong, Ji Hye Huh, Ki-Chul Sung, Jeong-Hun Shin, Hyeon Chang Kim, Jang Young Kim, Dae Ryong Kang
Diagnostics.2022; 12(8): 1967. CrossRef
Typ-2-Diabetes mellitus und gastrointestinale Krebsvorsorge
Hans Scherübl
Diabetes aktuell.2022; 20(06): 287. CrossRef
The Relationship between Diabetes Mellitus and Gastric Cancer and the Potential Benefits of Metformin: An Extensive Review of the Literature
Chin-Hsiao Tseng
Biomolecules.2021; 11(7): 1022. CrossRef
Type 2 diabetes and colorectal cancer screening: Findings from the English Longitudinal Study of Ageing
Christian von Wagner, Dorina Cadar, Ruth A Hackett, Panayotes Demakakos, Rebecca J Beeken, Stacy Cooper Bailey, Michael Wolf, Andrew Steptoe, Cristina Renzi, Sandro T Stoffel
Journal of Medical Screening.2020; 27(1): 25. CrossRef
Breast, cervical and colorectal cancer screening in adults with diabetes: a systematic review and meta-analysis
Dominika Bhatia, Iliana C. Lega, Wei Wu, Lorraine L. Lipscombe
Diabetologia.2020; 63(1): 34. CrossRef
Review: Diabetes, Obesity, and Cancer—Pathophysiology and Clinical Implications
Iliana C Lega, Lorraine L Lipscombe
Endocrine Reviews.2020; 41(1): 33. CrossRef
The Incidences and Characteristics of Various Cancers in Patients on Dialysis: a Korean Nationwide Study
Soon Kil Kwon, Joung-Ho Han, Hye-Young Kim, Gilwon Kang, Minseok Kang, Yeonkook J. Kim, Jinsoo Min
Journal of Korean Medical Science.2019;[Epub] CrossRef
Diabetes and Cancer: Cancer Should Be Screened in Routine Diabetes Assessment
Sunghwan Suh, Kwang-Won Kim
Diabetes & Metabolism Journal.2019; 43(6): 733. CrossRef

Associations between diabetes self-management and microvascular complications in patients with type 2 diabetes: Fatemeh Mehravar, Mohammad Ali Mansournia, Kourosh Holakouie-Naieni, Ensie Nasli-Esfahani, Nasrin Mansournia, Amir Almasi-Hashiani; Epidemiol Health. 2016;38:e2016004. Published online January 25, 2016; DOI: https://doi.org/10.4178/epih.e2016004

32,735 View
302 Download
39 Web of Science
32 Crossref

Abstract PDF

Abstract

OBJECTIVES
Diabetes is a major public health problem that is approaching epidemic proportions globally. Diabetes self-management can reduce complications and mortality in type 2 diabetic patients. The purpose of this study was to examine associations between diabetes self-management and microvascular complications in patients with type 2 diabetes.

METHODS

In this cross-sectional study, 562 Iranian patients older than 30 years of age with type 2 diabetes who received treatment at the Diabetes Research Center of the Endocrinology and Metabolism Research Institute of the Tehran University of Medical Sciences were identified. The participants were enrolled and completed questionnaires between January and April 2014. Patients’ diabetes self-management was assessed as an independent variable by using the Diabetes Self-Management Questionnaire translated into Persian. The outcomes were the microvascular complications of diabetes (retinopathy, nephropathy, and neuropathy), identified from the clinical records of each patient. A multiple logistic regression model was used to estimate odds ratios (ORs) and 95% confidence intervals (CIs) between diabetes self-management and the microvascular complications of type 2 diabetes, adjusting for potential confounders.

RESULTS

After adjusting for potential confounders, a significant association was found between the diabetes self-management sum scale and neuropathy (adjusted OR, 0.64; 95% CI, 0.45 to 0.92, p=0.01). Additionally, weak evidence was found of an association between the sum scale score of diabetes self-management and nephropathy (adjusted OR, 0.71; 95% CI, 0.47 to 1.05, p=0.09).

CONCLUSIONS

Among patients with type 2 diabetes, a lower diabetes self-management score was associated with higher rates of nephropathy and neuropathy.

Summary

Citations

Citations to this article as recorded by

Self-Management Practices and Perceived Risk of Complications Among Patients With Type II Diabetes in a Primary Care Setting
Berfin Oktay, Metin Fikret Genc
Cureus.2026;[Epub] CrossRef
Impact of Medication Adherence on Cardiovascular Outcomes in People with Type 2 Diabetes Mellitus and Disabilities
Onyou Kim, Myeongcheol Lee, Wonchang Hahn, Chang Hoon Kim, Seohyun Kim, Danbee Kang, Ki Hong Choi
Diabetes & Metabolism Journal.2026; 50(2): 418. CrossRef
Investigating the application of IoT mobile app and healthcare services for diabetic elderly: A systematic review
Jinglong Li, Rosalam Che Me, Faisul Arif Ahmad, Qisen Zhu, Vishal Sorathiya
PLOS ONE.2025; 20(4): e0321090. CrossRef
Factors influencing self-management and health-related quality of life in low-income patients with diabetes: a predictive model
Jihyon Pahn, Youngran Yang, Sun Hee Kim
International Journal of Nursing Studies Advances.2025; 8: 100349. CrossRef
Correlation between economic status and severity of type 2 diabetes mellitus in Indonesia: analysis of claim data from the national health insurance scheme, 2018–2022
Abdillah Ahsan, Wan Aisyiah Baros, Dedy Revelino Siregar, Yuyu Buono Ayuning Pertiwi, Maulida Gadis Utami, Leopold Aminde, Khaterina Kristina Manurung, Maya Febriyanti
BMJ Open.2025; 15(5): e091115. CrossRef
Diabetes rescue, engagement, and management (D-REM) for hypoglycemia: Clinical trial protocol of a community paramedic program to improve diabetes management among adults with severe hypoglycemia
Sumit Bhagra, Allison L. Ducharme-Smith, Michael B. Juntunen, Chad P. Liedl, Elizabeth H. Golembiewski, Wendy J. Sundt, Tami S. Krpata, Michelle A. Lampman, Anna L. Espinoza, Rozalina R. McCoy, Emma Campbell
PLOS One.2025; 20(6): e0322177. CrossRef
Insulin injection rotation and Diabetes Mellitus nutritional management education
Indah Rosdiana Narahaubun, Dian Handayani, Heri Kristianto, Heri Kristianto
Healthcare in Low-resource Settings.2024;[Epub] CrossRef
Exploring the relationship between self-management behaviour, family function and health information adoption behaviour in Chinese diabetic foot patients: a mixed-methods study protocol
Xueqing Wang, Panpan Tang, Lin Li, Yueying Jiang, Yuan Zhao, Leiwen Tang, Jing Shao, Dan Dan Chen
BMJ Open.2023; 13(8): e074739. CrossRef
Factors influencing self-quantification for patients with hypertension: A cross-sectional Study
Guiyue Ma, Haiyan Fang, Xiang Wang, Yahui Meng, Yu Zhu, Chuanying Zhang
Medicine.2023; 102(48): e36185. CrossRef
Association between self-care and complications among patients with type 2 diabetes mellitus: A cross-sectional study
Alaa Hamza Hermis, Fakhria Jaber Muhaibes
Medical Journal of Babylon.2023; 20(4): 762. CrossRef
Social Support as a Mediator between Depressive Symptoms and Self-Care Activities in Adults Patient with Type 2 Diabetes Mellitus
Pandan Enggarwati, Debie Dahlia, Riri Maria
Journal of Public Health Research.2022;[Epub] CrossRef
Indirect costs of non‐healing diabetic foot wounds in an African origin population in Barbados
André R. Greenidge, Simon Naitram, Kim R. Quimby, Simon G. Anderson, R. Clive Landis
Diabetic Medicine.2022;[Epub] CrossRef
Relationship Between COVID-19-related Factors and Self-management Behaviors in People with Type-2 Diabetes: A Cross-sectional Study
Maryam Binesh, Aliakbar Pahlevanian, Sajjad Rahimi Pordanjani, Zahra Ahmadizadeh
Middle East Journal of Rehabilitation and Health Studies.2022;[Epub] CrossRef
Comparing the effects of SMS-based education with group-based education and control group on diabetes management: a randomized educational program
Hourvash Haghighinejad, Leila Liaghat, Fatemeh Malekpour, Peyman Jafari, Kaveh Taghipour, Mehrdad Rezaie, Parisa Jooya, Hamidreza Ghazipoor, Mani Ramzi
BMC Primary Care.2022;[Epub] CrossRef
Prevalence of diabetic retinopathy in the Eastern Mediterranean Region: a systematic review and meta-analysis
Alireza Heiran, Seyede Pegah Azarchehry, Saeid Dehghankhalili, Mehrdad Afarid, Sonia Shaabani, Alireza Mirahmadizadeh
Journal of International Medical Research.2022;[Epub] CrossRef
The effectiveness of patient-centered care vs. usual care in type 2 diabetes self-management: A systematic review and meta-analysis
Kainat Asmat, Khairunnisa Dhamani, Raisa Gul, Erika Sivarajan Froelicher
Frontiers in Public Health.2022;[Epub] CrossRef
A health-based coaching program for diabetes self-management (DSM) practice: A sequential exploratory mixed-method approach
Rian Adi Pamungkas, Kanittha Chamroonsawasdi, Phitaya Charupoonphol, Paranee Vatanasomboon
Endocrinología, Diabetes y Nutrición.2021; 68(7): 489. CrossRef
Inter-relationship of risk factors and pathways associated with chronic kidney disease in patients with type 2 diabetes mellitus: a structural equation modelling analysis
C.-P. Wang, Y.-C. Lu, W.-C. Hung, I.-T. Tsai, Y.-H. Chang, D.-W. Hu, C.-C. Hsu, C.-C. Wu, C.-T. Wei, F.-M. Chung, Y.-J. Lee
Public Health.2021; 190: 135. CrossRef
Assessment of Self-Care Activities Using Diabetes SelfManagement Questionnaire (DSMQ) amongst Diabetes Patients Attending a Rural Health Training Centre in Lucknow
Mohammad Suhail Khan, Syed Esam Mahmood, Ausaf Ahmad, Anas Ahmad Khan, Islam Arfin
Journal of Evolution of Medical and Dental Sciences.2021; 10(18): 1324. CrossRef
Research Progress of Fibrinogen in Diabetes Mellitus and Its Complications
寒贾
Advances in Clinical Medicine.2021; 11(11): 5201. CrossRef
Symptom Clusters and Quality of Life in Patients with Type 2 Diabetes Mellitus
Su-Yeon Hong, Yang-Sook Yoo
Korean Journal of Adult Nursing.2021; 33(5): 498. CrossRef
A health-based coaching program for diabetes self-management (DSM) practice: A sequential exploratory mixed-method approach
Rian Adi Pamungkas, Kanittha Chamroonsawasdi, Phitaya Charupoonphol, Paranee Vatanasomboon
Endocrinología, Diabetes y Nutrición (English ed.).2021; 68(7): 489. CrossRef
Determinants of glycemic control: Phase 2 analysis from nationwide diabetes report of National Program for Prevention and Control of Diabetes (NPPCD-2018)
Alireza Esteghamati, Faramarz Ismail-Beigi, Pegah Khaloo, Fatemeh Moosaie, Hamid Alemi, Mohammad Ali Mansournia, Mohsen Afarideh, Ghasem Janbabaei Molla, Teyyeb Ghadimi, Mehdi Shadnoush, Jamshid Kermanchi, Fatemeh Ghaemi
Primary Care Diabetes.2020; 14(3): 222. CrossRef
A Study on Knowledge and Self-Care Practices about Type-2 Diabetes Mellitus among patients attending selected Tertiary HealthCare Facilities in Coastal Karnataka
Anjali Shrivastva, Sameer Phadnis, Karthik Rao N, Manisha Gore
Clinical Epidemiology and Global Health.2020;[Epub] CrossRef
Prefrontal cortex brain damage and glycemic control in patients with type 2 diabetes
Sarah E. Choi, Bhaswati Roy, Matthew Freeby, Rashmi Mullur, Mary A. Woo, Rajesh Kumar
Journal of Diabetes.2020; 12(6): 465. CrossRef
Self-Care in Adults with Type 2 Diabetes Mellitus: A Systematic Review
Rebeca Barbosa da Rocha, Cristiano Sales Silva, Vinícius Saura Cardoso
Current Diabetes Reviews.2020; 16(6): 598. CrossRef
The validity of the diabetes self-management questionnaire (DSMQ) in Hungarian patients with type 2 diabetes
Agnes Vincze, Antonia Losonczi, Adrienne Stauder
Health and Quality of Life Outcomes.2020;[Epub] CrossRef
Perspectives of pain in patients with type 2 diabetes
Julienne K Kirk, Jaimie C Hunter, Shannon L Mihalko, Suzanne C Danhauer, Sally A Shumaker
Expert Review of Endocrinology & Metabolism.2019; 14(3): 215. CrossRef
Association of Polymorphisms in miRNA Processing Genes With Type 2 Diabetes Mellitus and Its Vascular Complications in a Southern Chinese Population
Zihao Wen, Xiaoqian Zou, Xin Xie, Shaoling Zheng, Xiaojing Chen, Kehui Zhu, Shirui Dong, Jiayu Liang, Xiuxia Huang, Dandan Liu, Yao Wang, Yumei Liu, Jing Wu, Yuting Ying, Kailiang Liu, Congying Lu, Baohuan Zhang, Guang Yang, Chunxia Jing, Lihong Nie
Frontiers in Endocrinology.2019;[Epub] CrossRef
Prevalence, Incidence and Ecological Determinants of Diabetic Retinopathy in Iran: Systematic Review and Meta-analysis
Golnoush Sadat Mahmoudi Nezhad, Reza Razeghinejad, Mohsen Janghorbani, Alireza Mohamadian, Mohammad Hassan Jalalpour, Somaye Bazdar, Alireza Salehi, Hossein Molavi Vardanjani
Journal of Ophthalmic and Vision Research.2019; 14(3): 321. CrossRef
Interactions of TRAF6 and NLRX1 gene polymorphisms with environmental factors on the susceptibility of type 2 diabetes mellitus vascular complications in a southern Han Chinese population
Chengli Zeng, Zixing Zhou, Yajing Han, Zihao Wen, Congcong Guo, Shiqi Huang, Di Xiao, Xiaohong Ye, Meiling Ou, Chuican Huang, Xingguang Ye, Guang Yang, Chunxia Jing, Lihong Nie
Journal of Diabetes and its Complications.2017; 31(12): 1652. CrossRef
Psychometric properties of the Diabetes Self-Management Questionnaire (DSMQ) in Urdu
Allah Bukhsh, Shaun Wen Huey Lee, Priyia Pusparajah, Andreas Schmitt, Tahir Mehmood Khan
Health and Quality of Life Outcomes.2017;[Epub] CrossRef

Risk factors for amputation in patients with diabetic foot ulcer in southwest Iran: a matched case-control study: Mohammad Kogani, Mohammad Ali Mansournia, Amin Doosti-Irani, Kourosh Holakouie-Naieni; Epidemiol Health. 2015;37:e2015044. Published online October 5, 2015; DOI: https://doi.org/10.4178/epih/e2015044

32,419 View
309 Download
18 Web of Science
20 Crossref

Abstract PDF

Abstract

OBJECTIVES
Amputation is a multifactorial complication in diabetic patients. The aim of this study was to determine the risk factors associated with amputation in patients with diabetic foot ulcers.

METHODS

This matched case-control study was conducted based on new cases of amputation from March 2012 to November 2014. We selected new cases who had undergone amputation, and the control group was chosen from the cities or areas where the cases resided. Each case was matched with two controls based on the duration of diabetes and location. Conditional logistic regression was used to evaluate the associations between potential risk factors and amputation.

RESULTS

A total of 131 cases were compared with 262 controls. The results of the adjusted model showed that sex (odds ratio [OR], 8.66; 95% confidence interval [CI], 2.68 to 27.91), fewer than two hemoglobin A1c (HbA1c) tests per year (OR, 13.97; 95% CI, 4.97 to 39.26), unsuitable shoes (OR, 5.50; 95% CI, 2.20 to 13.77), smoking (OR, 3.44; 95% CI, 1.45 to 8.13), and body mass index (OR, 1.20; 95% CI, 1.03 to 1.41) were associated with amputation in diabetic patients.

CONCLUSIONS

The most important factors associated with amputation were females, irregular monitoring of HbA1c levels, improper footwear, and smoking. Developing educational programs and working to ensure a higher quality of care for diabetic patients are necessary steps to address these issues.

Summary

Citations

Citations to this article as recorded by

Comparison of the Effects of Insoles Used in Diabetes Mellitus on Plantar Pressure: A Pilot Study
Alireza Mossayebi, Suzan Cansel Doğru, Ehsan Shakouri
Afyon Kocatepe University Journal of Sciences and Engineering.2026; (Advanced O): 238. CrossRef
Reliability and Validation of Three Scoring Systems in the Assessment of Diabetic Foot Ulcers
Mruthunjaya S Bevinamarad, Ramakanth Baloorkar, Shivanagouda S Patil, Shailesh Kannur, Kanishk Kanishk, Nagaraj Biradar, Bhuvaneshwari Gachinmath
Cureus.2026;[Epub] CrossRef
Advances in biomaterials and regenerative medicine for diabetic foot ulcer therapy
Yi-Ran Li, Xiao-Shan Lai, Hio-Fai Cheong, Ding-Kun Gui, Yong-Hua Zhao, You-Hua Xu
Ageing Research Reviews.2025; 109: 102779. CrossRef
Risk of Diabetic Foot Ulcer Based on Modifiable Factors in Patients With Diabetes mellitus : A Cross-sectional Study
Anita Joeliantina, Dwi Adji Norontoko, Moch. Bahrudin, Sri Hardi Wuryaningsih
Malaysian Journal of Medicine and Health Sciences.2025; 21(3): 122. CrossRef
The Burden of Diabetic Foot Ulcers in Urban India: A Community Healthcare Setup-Based Study
Priti Patil, Satish Mishra, Anita Gadgil, Prashant Bhandarkar, Nobhojit Roy, Laxmi K. Dwivedi
Indian Journal of Endocrinology and Metabolism.2024; 28(5): 494. CrossRef
Prevalence and determinants of lower extremity amputations among type I and type II diabetic patients: A multicenter‐based study
Lawrence Sena Tuglo
International Wound Journal.2023; 20(4): 903. CrossRef
The prevalence of uncontrolled diabetes mellitus in patients with type 2 diabetes: a multicenter cross-sectional study
Monir Lorestanifar, Masoomeh Mosayebi Molasaraei, Reyhaneh Jashaninejad, Saman Khoshmanesh, Amin Doosti-Irani
Journal of Diabetes & Metabolic Disorders.2023; 22(1): 787. CrossRef
Knowledge and practice of diabetic foot care and the prevalence of diabetic foot ulcers among diabetic patients of selected hospitals in the Volta Region, Ghana
Lawrence Sena Tuglo, Felix Kwasi Nyande, Percival Delali Agordoh, Eunice Berko Nartey, Zhongqin Pan, Lydia Logosu, Atsu Eyram Dei‐Hlorlewu, Desire Koku Haligah, Linda Osafo, Simon Taful, Minjie Chu
International Wound Journal.2022; 19(3): 601. CrossRef
Preventive foot self-care practice and associated factors among diabetic patients attending the university of Gondar comprehensive specialized referral hospital, Northwest Ethiopia, 2021
Enyew Getaneh Mekonen, Tizita Gebeyehu Demssie
BMC Endocrine Disorders.2022;[Epub] CrossRef
Uso de tecnologías de información y comunicación para promover la autogestión de ulceras por pie diabético
Ana Maria Murillo Salamanca, Alejandra María Alvarado-García
Revista Cuidarte.2022;[Epub] CrossRef
Common late complications of longitudinal forefoot amputations in neuropathic foot treatment
Rodrigo Sousa Macedo, Lucas Sousa Macedo, Marcos Hideyo Sakaki, Rafael Barban Sposeto, Rafael Trevisan Ortiz, Marcos de Andrade Corsato, Alexandre Leme Godoy-Santos, Túlio Diniz Fernandes
Journal of Wound Care.2021; 30(6): 498. CrossRef
Biomechanical modelling of diabetic foot ulcers: A computational study
Gurpreet Singh, Shubham Gupta, Arnab Chanda
Journal of Biomechanics.2021; 127: 110699. CrossRef
Prediction of diabetic foot ulcer progression: a computational study
Shubham Gupta, Gurpreet Singh, Arnab Chanda
Biomedical Physics & Engineering Express.2021; 7(6): 065020. CrossRef
Predictors of Foot Ulcers Among Diabetic Patients at a Tertiary Care Center, Egypt
Yasmine Samir Galal, Walaa Ahmed Khairy, Ahmed Taha, Tarek Tawfik Amin
Risk Management and Healthcare Policy.2021; Volume 14: 3817. CrossRef
Glycemic control and awareness of foot care indiabetic foot syndrome
Ayten Guner Atayoglu, Ali Timucin Atayoglu, Rahime Ozgur, Hammad Khan
INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine).2021; 17(3): 200. CrossRef
Are arch‐conforming insoles a good fit for diabetic foot? Insole customized design by using finite element analysis
Jianwei Niu, Jing Liu, Yanling Zheng, Linghua Ran, Zhigang Chang
Human Factors and Ergonomics in Manufacturing & Service Industries.2020; 30(4): 303. CrossRef
Foot care knowledge, attitudes and practices among patients with diabetic foot and amputation in St. Kitts and Nevis
Gracelyn Hanley, Piao‐Yi Chiou, Chieh‐Yu Liu, Hui‐Mei Chen, Stefani Pfeiffer
International Wound Journal.2020; 17(5): 1142. CrossRef
Patient-level predictors of diabetes-related lower extremity amputations at a quaternary hospital in South Africa
Sifiso Mtshali, Ozayr Mahomed, Manal S. Fawzy
PLOS ONE.2020; 15(10): e0240588. CrossRef
Mobile phone text messaging to improve knowledge and practice of diabetic foot care in a developing country: Feasibility and outcomes
Zeinab M. Hassan
International Journal of Nursing Practice.2017;[Epub] CrossRef
Differences in foot self-care and lifestyle between men and women with diabetes mellitus
Mariana Angela Rossaneis, Maria do Carmo Fernandez Lourenço Haddad, Thaís Aidar de Freitas Mathias, Sonia Silva Marcon
Revista Latino-Americana de Enfermagem.2016;[Epub] CrossRef

Effect change of obesity on diabetes depending on measurement: self-reported body mass index from 2012 Community Health Survey vs. directly measured from the Korea National Health and Nutrition Examination Survey: Kyuhyun Yoon, Kyungduk Min, Heeran Chun, Soong-Nang Jang, Sung-il Cho; Epidemiol Health. 2015;37:e2015001. Published online January 6, 2015; DOI: https://doi.org/10.4178/epih/e2015001

29,991 View
175 Download
2 Web of Science
1 Crossref

Abstract Summary PDF

Abstract

OBJECTIVES
Obesity is a well-recognized risk factor for type 2 diabetes mellitus (DM) among young and middle-aged adults in South Korea. To elaborate on the association between obesity and DM, subjective data from self-reporting survey or objective data from health examination is generally used. This study was conducted to validate the change of association from using these different measurements.

METHODS

Community Health Survey data and Korea National Health and Nutrition Examination Survey data, as subjective and objective data respectively, were used. Population, resident in Seoul and over 45 aged, were selected for the study and the association between obesity and DM were defined by using multivariate logistic regression model.

RESULTS

In subjective data, DM prevalence was 12.4% (male, 14.7; female, 10.6) and obesity prevalence was 26.0% (male, 29.2; female, 23.4). Whereas, in objective data, DM prevalence was 15.0% (male, 17.8; female, 12.9), and obese population was 32.4% (male, 34.4; female, 30.8). Based on the effect of obesity on DM prevalence from each data, using objective data increased the impact of obesity. Difference of relative risk of obesity between from subjective data and from objective was bigger in female than male and statistically significant.

CONCLUSIONS

The differences of association pattern between subjective and objective data were found, due to higher obesity prevalence in objective data, and discrepancies of socio-economic status. These discrepancies could be inevitable Therefore we have to face them proactively, and understand the different aspect of various variables from different measurement.

Summary

Korean summary
지역사회건강조사는 각 지역의 건강관련 지표들을 제시하기 위한 기본 목적을 가지고 있으나, 자가보고를 통한 자료수집에 의존하고 있다는 면에서 연구결과의 신뢰성에 한계를 가지고 있다고 인식되어왔다. 본 연구는 실측자료와 자가보고자료에서의 분석결과차이를 파악함으로써, 이러한 인식에 대한 직접적 평가와 더불어, 자가보고자료에 대한 활용도 증진에 기여하고자 하였다. 연구 결과, 비만의 당뇨병에 대한 영향은 실측자료보다 자가보고자료에서 더 작아졌고, 이러한 차이는 남성에서보다 여성에서 더 크게 나타났다.

Citations

Citations to this article as recorded by

Comparison of estimates and time series stability of Korea Community Health Survey and Korea National Health and Nutrition Examination Survey
Ji Son Ki, Ho Kim
Epidemiology and Health.2019; 41: e2019012. CrossRef

Commentary

Persistent Organic Pollutants and Obesity-Related Metabolic Dysfunction: Focusing on Type 2 Diabetes: Duk-Hee Lee; Epidemiol Health. 2012;34:e2012002. Published online January 27, 2012; DOI: https://doi.org/10.4178/epih/e2012002

27,808 View
156 Download
18 Crossref

Abstract PDF

Abstract

Even though obesity is a well-established risk factor of type 2 diabetes, there is emerging evidence that persistent organic pollutants (POPs), a variety of lipophilic chemicals accumulated in adipose tissue, may be critically involved in the pathogenesis of type 2 diabetes. Among various POPs, serum concentrations of organochlorine pesticides and polychlorinated biphenyls (PCBs) were the most strongly and consistently linked to type 2 diabetes in both cross-sectional and prospective studies. In particular, obesity did not seem to be related to type 2 diabetes among persons with very low serum concentrations of POPs, suggesting a more fundamental role of chlorinated POPs in the pathogenesis of type 2 diabetes. These POPs were also associated with obesity, insulin resistance, and adverse lipid profiles like high triglyceride and low high-density lipoprotein (HDL) cholesterol among persons without diabetes, all metabolic dysfunctions commonly observed before developing type 2 diabetes. Recent animal studies supported the findings from epidemiological studies. If all these findings on POPs are true, it suggests that any effort to reduce the external and internal exposure to POPs would be necessary to decrease the social burden of type 2 diabetes.

Summary

Citations

Citations to this article as recorded by

Chlorantraniliprole exposure aggravates high-fat diet-induced metabolic disorders in mice by regulating gut microbiota and its metabolites
Ting Gu, Jie Lin, Jiani Yang, William Mumby, Quancai Sun, Ye Peng
Food Science and Human Wellness.2025; 14(1): 9250079. CrossRef
Polychlorinated biphenyls-153 induces fat accumulation and lifespan shortening through CYP450 family genes in Caenorhabditis elegans
Zhi Qu, Panpan Wang, Yalu Wang, Peisen Guo, Guimiao Lin, Peixi Wang, Zengli Yu, Nan Liu
Journal of Environmental Sciences.2025; 158: 72. CrossRef
A state-of-the-science review and guide for measuring environmental exposure biomarkers in dried blood spots
Tyler A. Jacobson, Jasdeep S. Kler, Yeunook Bae, Jiexi Chen, Daniel T. Ladror, Ramsunder Iyer, Denise A. Nunes, Nathan D. Montgomery, Joachim D. Pleil, William E. Funk
Journal of Exposure Science & Environmental Epidemiology.2023; 33(4): 505. CrossRef
Associations between exposure to brominated flame retardants and metabolic syndrome and its components in U.S. adults
Zhiqiang Che, Huixun Jia, Renjie Chen, Keyu Pan, Zhe Fan, Chang Su, Zhenyu Wu, Tao Zhang
Science of The Total Environment.2023; 858: 159935. CrossRef
Do perfluoroalkyl substances aggravate the occurrence of obesity-associated glucolipid metabolic disease?
Huinian Liu, Wenli Hu, Xin Li, Fangwen Hu, Yanni Xi, Zhu Su, Yicai Huang, Bo Liu, Chang Zhang
Environmental Research.2021; 202: 111724. CrossRef
Associations between the exposure to persistent organic pollutants and type 2 diabetes in East China: A case-control study
Xu Han, Lingling Meng, Yingming Li, An Li, Mary E. Turyk, Ruiqiang Yang, Pu Wang, Ke Xiao, Junpeng Zhao, Jianqing Zhang, Qinghua Zhang, Guibin Jiang
Chemosphere.2020; 241: 125030. CrossRef
Exposure to organochlorine pesticides and the risk of type 2 diabetes in the population of East China
Xu Han, Feng Zhang, Lingling Meng, Yuedong Xu, Yingming Li, An Li, Mary E. Turyk, Ruiqiang Yang, Pu Wang, Jianqing Zhang, Qinghua Zhang, Guibin Jiang
Ecotoxicology and Environmental Safety.2020; 190: 110125. CrossRef
Persistent organic pollutants and gestational diabetes: A multi-center prospective cohort study of healthy US women
Mohammad L. Rahman, Cuilin Zhang, Melissa M. Smarr, Sunmi Lee, Masato Honda, Kurunthachalam Kannan, Fasil Tekola-Ayele, Germaine M. Buck Louis
Environment International.2019; 124: 249. CrossRef
Oleanolic acid attenuates PCBs-induced adiposity and insulin resistance via HNF1b-mediated regulation of redox and PPARγ signaling
Shuhao Su, Guangyuan Wu, Xiaodong Cheng, Junshu Fan, Jie Peng, Hongfei Su, Zhongrui Xu, Meng Cao, Zi Long, Yiming Hao, Ge Li, Shuang Li, Chunxu Hai, Xin Wang
Free Radical Biology and Medicine.2018; 124: 122. CrossRef
Exposure to an environmentally relevant mixture of organochlorine compounds and polychlorinated biphenyls Promotes hepatic steatosis in male Ob/Ob mice
Charlee Mulligan, Sandeep Kondakala, Eun‐Ju Yang, John V. Stokes, James A. Stewart, Barbara L. F. Kaplan, George E. Howell
Environmental Toxicology.2017; 32(4): 1399. CrossRef
Polychlorinated biphenyls exposure-induced insulin resistance is mediated by lipid droplet enlargement through Fsp27
Hye Young Kim, Woo Young Kwon, Yeon A. Kim, Yoo Jin Oh, Seung Hee Yoo, Mi Hwa Lee, Ju Yong Bae, Jong-Min Kim, Young Hyun Yoo
Archives of Toxicology.2017; 91(6): 2353. CrossRef
Polychlorinated biphenyls-153 induces metabolic dysfunction through activation of ROS/NF-κB signaling via downregulation of HNF1b
Hao Wu, Weihua Yu, Fansen Meng, Jie Mi, Jie Peng, Jiangzheng Liu, Xiaodi Zhang, Chunxu Hai, Xin Wang
Redox Biology.2017; 12: 300. CrossRef
Protective role of antioxidants capacity of Hyrtios aff. Erectus sponge extract against mixture of persistent organic pollutants (POPs)-induced hepatic toxicity in mice liver: biomarkers and ultrastructural study
Nehad M. Abd El-Moneam, Mohamed A. Shreadah, Samy A. El-Assar, Asmaa Nabil-Adam
Environmental Science and Pollution Research.2017; 24(27): 22061. CrossRef
Health status of male steel workers at an electric arc furnace (EAF) in Trentino, Italy
Roberto Cappelletti, Marcello Ceppi, Justina Claudatus, Valerio Gennaro
Journal of Occupational Medicine and Toxicology.2016;[Epub] CrossRef
High serum organochlorine pesticide concentrations in diabetics of a cotton producing area of the Benin Republic (West Africa)
Colette S. Azandjeme, Hélène Delisle, Benjamin Fayomi, Pierre Ayotte, Francois Djrolo, Dismand Houinato, Michèle Bouchard
Environment International.2014; 69: 1. CrossRef
Polychlorinated biphenyl exposure, diabetes and endogenous hormones: a cross-sectional study in men previously employed at a capacitor manufacturing plant
Victoria Persky, Julie Piorkowski, Mary Turyk, Sally Freels, Robert Chatterton, John Dimos, H Leon Bradlow, Lin Kaatz Chary, Virlyn Burse, Terry Unterman, Daniel W Sepkovic, Kenneth McCann
Environmental Health.2012;[Epub] CrossRef
Exploring the Obesity Epidemic
Carolyn M. Matthews
Baylor University Medical Center Proceedings.2012; 25(3): 276. CrossRef
LINE-1 methylation in visceral adipose tissue of severely obese individuals is associated with metabolic syndrome status and related phenotypes
Valérie Turcot, André Tchernof, Yves Deshaies, Louis Pérusse, Alexandre Bélisle, Simon Marceau, Simon Biron, Odette Lescelleur, Laurent Biertho, Marie-Claude Vohl
Clinical Epigenetics.2012;[Epub] CrossRef

Original Articles

Adiponectin is Associated with Impaired Fasting Glucose in the Non-Diabetic Population: Sang Yeun Kim, Sun Ju Lee, Hyoun Kyoung Park, Ji Eun Yun, Myoungsook Lee, Jidong Sung, Sun Ha Jee; Epidemiol Health. 2011;33:e2011007. Published online August 20, 2011; DOI: https://doi.org/10.4178/epih/e2011007

29,930 View
113 Download
8 Crossref

Abstract PDF

Abstract

<sec><title>OBJECTIVES</title>Adiponectin is strongly associated with diabetes in the Western population. However, whether adiponectin is independently associated with impaired fasting glucose (IFG) in the non-obese population is unknown.</sec><sec><title>METHODS</title>The serum adiponectin, insulin resistance (IR), and waist circumference (WC) of 27,549 healthy Koreans were measured. Individuals were then classified into tertile groups by gender. IFG was defined as a fasting serum glucose of 100-125 mg/dL without diabetes. IR was calculated using the homeostasis model assessment of insulin resistance (HOMA-IR). The association of adiponectin and IFG was determined using logistic regression analysis.</sec><sec><title>RESULTS</title>WC and adiponectin were associated with IFG in both men and women. However, the association of WC with IFG was attenuated in both men and women after adjustment for the HOMA-IR. Adiponectin was still associated with IFG after adjustment for and stratification by HOMA-IR in men and women. Strong combined associations of IR and adiponectin with IFG were observed in men and women. Multivariate adjusted odds ratios (ORs) (95% confidence interval [CI]) among those in the highest tertile of IR and the lowest tertile of adiponectin were 9.8 (7.96 to 12.07) for men and 24.1 (13.86 to 41.94) for women.</sec><sec><title>CONCLUSION</title>These results suggest that adiponectin is strongly associated with IFG, and point to adiponectin as an additional diagnostic biomarker of IFG in the non-diabetic population.</sec>

Summary

Citations

Citations to this article as recorded by

ASSOCIATION OF SERUM ADIPONECTIN IN NON-DIABETIC HEALTHY YOUNG ADULT OF FIRST-DEGREE RELATION OF T2DM INDIVIDUALS
HARSHVARDHAN, BHARTI KAWATRA, HARPREET KAUR WALLIA
Asian Journal of Pharmaceutical and Clinical Research.2025; : 247. CrossRef
Determination of risk factors associated with inflammation in hypertensive patients with type-2 diabetes mellitus in a Palestinian Diabetes Study
Mohammed S. Ellulu, Ihab A. Naser, Sahar M. Abuhajar, Ahmed A. Najim
Current Medical Research and Opinion.2021; 37(9): 1451. CrossRef
Insulin and Proinsulin Dynamics Progressively Deteriorate From Within the Normal Range Toward Impaired Glucose Tolerance
Norimitsu Murai, Naoko Saito, Eriko Kodama, Tatsuya Iida, Kentaro Mikura, Hideyuki Imai, Mariko Kaji, Mai Hashizume, Yasuyoshi Kigawa, Go Koizumi, Rie Tadokoro, Chiho Sugisawa, Kei Endo, Toru Iizaka, Ryo Saiki, Fumiko Otsuka, Shun Ishibashi, Shoichiro Nag
Journal of the Endocrine Society.2020;[Epub] CrossRef
Association between the level of circulating adiponectin and prediabetes: A meta‐analysis
Huasheng Lai, Nie Lin, Zhenzhen Xing, Huanhuan Weng, Hua Zhang
Journal of Diabetes Investigation.2015; 6(4): 416. CrossRef
Comparison of salivary and plasma adiponectin and leptin in patients with metabolic syndrome
Supanee Thanakun, Hisashi Watanabe, Sroisiri Thaweboon, Yuichi Izumi
Diabetology & Metabolic Syndrome.2014;[Epub] CrossRef
Adiponectin as predictor for diabetes among pre-diabetic groups
Hyon-Suk Kim, Jaeseong Jo, Jung Eun Lim, Young Duk Yun, Soo Jin Baek, Tae-Yong Lee, Kap Bum Huh, Sun Ha Jee
Endocrine.2013; 44(2): 411. CrossRef
Attenuation of plasma annexin A1 in human obesity
Anna Kosicka, Adam D. Cunliffe, Richard Mackenzie, M. Gulrez Zariwala, Mauro Perretti, Roderick J. Flower, Derek Renshaw
The FASEB Journal.2013; 27(1): 368. CrossRef
Association between ADIPOQ SNPs with plasma adiponectin and glucose homeostasis and adiposity phenotypes in the IRAS Family Study
S. Sandy An, Anthony J.G. Hanley, Julie T. Ziegler, W. Mark Brown, Steven M. Haffner, Jill M. Norris, Jerome I. Rotter, Xiuqing Guo, Y.-D. Ida Chen, Lynne E. Wagenknecht, Carl D. Langefeld, Donald W. Bowden, Nicholette D. Palmer
Molecular Genetics and Metabolism.2012; 107(4): 721. CrossRef

Effect of Medicine Adherence on the Occurrence of Cerebrovascular Disorders in Diabetes Mellitus Patients: Il-Su Park, Hae-Sook Sohn; Epidemiol Health. 2011;33:e2011001. Published online January 28, 2011; DOI: https://doi.org/10.4178/epih/e2011001

25,039 View
85 Download
3 Crossref

Abstract PDF

Abstract

<sec><title>OBJECTIVES</title>To assess the association between the occurrence of cerebrovascular disorders and a medication adherence in diabetes mellitus patients.</sec><sec><title>METHODS</title>Medical records from 1,114 new patients with diabetes mellitus were collected and the occurrence of cerebrovascular disorders was observed. Data was gathered from the health examination records of diabetes mellitus patients registered at the Korean Metabolic Syndrome Research from 1996 to 2005, medication records from the National Health Insurance Corporation and death data from the National Statistics Office from 1997 to 2007. Hazard ratios were analyzed using the Cox proportional hazard model to test the association between the occurrence of cerebrovascular disorders and the level of medication adherence. Medication adherence was calculated using Continuous measure of Medication Acquisition (CMA).</sec><sec><title>RESULTS</title>Of 1,114 diabetes mellitus patients, cerebrovascular disorders occurred in 67 cases (6.1%). The mean duration for the development of a cerebrovascular disorder was 3.82 yr. Medication adherence (≥0.8 vs. <0.5: HR, 3.26; 95% CI, 1.47-7.21, ≥0.8 vs. 0.5-0.7 HR, 0.99; 95% CI, 0.33-2.95) was an independent factor associated with the occurrence of cerebrovascular disorders in diabetes mellitus.</sec><sec><title>CONCLUSION</title>Increased medication adherence is necessary to prevent the occurrence of cerebrovascular disorders in diabetes mellitus patients. Furthermore we propose that CMA be considered as a method for monitoring medication adherence in clinics.</sec>

Summary

Citations

Citations to this article as recorded by

Effects of early medication treatment and metformin use for cancer prevention in diabetes patients: a nationwide sample cohort study in Korea using extended landmark time analysis
Hwa Jeong Seo, Hyun Sook Oh
Epidemiology and Health.2021; 43: e2021103. CrossRef
Clinical inertia, reverse clinical inertia, and medication non-adherence in type 2 diabetes
D. Giugliano, M. I. Maiorino, G. Bellastella, K. Esposito
Journal of Endocrinological Investigation.2019; 42(5): 495. CrossRef
El incumplimiento en el tratamiento de la diabetes mellitus tipo 2 en España
Emilio Márquez Contreras
Hipertensión y Riesgo Vascular.2012; 29: 8. CrossRef

Comparison of Prevalence of Metabolic Syndrome Between Korean Emigrants and Host Country Residents in Japan and China-The Korean Emigrant Study: Myung-Hee Shin, Mi Kyung Kim, Zhong Min Li, Hyun-Kyung Oh, Soo Ryang Kim, Miyuki Taniguchi, Jinnv Fang; Epidemiol Health. 2010;32:e2010005. Published online May 7, 2010; DOI: https://doi.org/10.4178/epih/e2010005

29,162 View
122 Download
4 Crossref

Abstract PDF

Abstract

<sec><title>OBJECTIVES</title>This study aims to compare the prevalence of metabolic syndrome between Korean emigrants (KEs) and their host country residents in Japan and China.</sec><sec><title>METHODS</title>The Korean Emigrant Study (KES) is a cohort study initiated in 2005 to elucidate the effect of genetic susceptibility and environmental change on hypertension, diabetes, and metabolic syndrome. Equal numbers of KEs and host country residents, aged 30 or over, were recruited from three regions; Kobe-Osaka in Japan (total number=965), Yanbian in China (n=1,019), and Changchun in China (n=949).</sec><sec><title>RESULTS</title>The age-adjusted prevalences of metabolic syndrome among KEs in Kobe-Osaka were significantly higher than those among Japanese (in men 24.0% vs. 15.6%, p=0.04, in women 8.4% vs. 2.7%, p=0.01), while the age-adjusted prevalences among KEs in Changchun were similar to those among Chinese (in men 11.7% vs. 16.1%, p=0.37, in women 28.3% vs. 30.1%, p=0.91). The age-adjusted prevalences were generally higher in Yanbian than other regions, and KEs had higher prevalence than Chinese in men but not in women (in men 37.9% vs. 28.3%, p=0.03, women 46.0% vs. 50.6%, p=0.44). The components with significant ethnic differences in prevalence were high blood pressure and abdominal obesity in Japan, and triglyceride in China. The most influential component in diagnosing metabolic syndrome was abdominal obesity in men and triglyceride in women.</sec><sec><title>CONCLUSION</title>The prevalence of metabolic syndrome was higher in KEs than in host country residents in Japan but not in China. Abdominal obesity and triglyceride are both discriminating and influential components in metabolic syndrome.</sec>

Summary

Citations

Citations to this article as recorded by

New Common and Rare Variants Influencing Metabolic Syndrome and Its Individual Components in a Korean Population
Ho-Sun Lee, Yongkang Kim, Taesung Park
Scientific Reports.2018;[Epub] CrossRef
Cohort Profile: The Korean Genome and Epidemiology Study (KoGES) Consortium
Yeonjung Kim, Bok-Ghee Han
International Journal of Epidemiology.2017; 46(2): e20. CrossRef
Is There Disparity in Cardiovascular Health Between Migrant Workers and Native Workers?
Hyeonkyeong Lee, Sunghye Cho, Yune Kyong Kim, Jung Hee Kim
Workplace Health & Safety.2016; 64(8): 350. CrossRef
Coffee Intake and Liver Enzyme Association in Korean Immigrants and Japanese: A Comprehensive Cross-Sectional Study
Soo Ki Kim, Myung-Hee Shin, Kayo Sugimoto, Soo Ryang Kim, Susumu Imoto, Ke Ih Kim, Miyuki Taniguchi, Hyun-Kyung Oh, Yoshihiko Yano, Yoshitake Hayashi, Masatoshi Kudo
Digestive Diseases.2016; 34(6): 665. CrossRef

Relationship between serum gamma-glutamyltransferase and metabolic syndrome among Korean non-diabetic adults.: Wee Hyun Park, Shung Chull Chae, Byung Yeol Chun, Kyung Eun Lee, Bo Wan Kim, Jung Guk Kim, Ji Seun Lim, Sun Kyun Park; Korean J Epidemiol. 2008;30(2):206-215. Published online December 31, 2008; DOI: https://doi.org/10.4178/kje.2008.30.2.206

65,535 View
20 Download
3 Crossref

Abstract PDF

Abstract

PURPOSE
This study was conducted to investigate the association of gamma-glutamyltransferase (GGT) with metabolic syndrome among non-diabetic adults.

METHODS

This study was conducted in a rural area, South Korea from August, 2003 to November, 2003. The study subjects were 1,023 sampled persons aged from 40 years and older (male 377, female 646). We analyzed the association between GGT with metabolic syndrome by multiple logistic regression analysis using SAS 9.1 version.

RESULTS

The prevalence of metabolic syndrome in this study was 28.8%. The prevalence of metabolic syndrome was increased by quartiles of serum GGT level (P for trend <0.05). The prevalence of metabolic alterations fitting the criteria of the metabolic syndrome by quartiles of serum GGT level were almost significantly increased except for the criterion of low high density lipoprotein (HDL) cholesterol with adjustment for age and alcohol intake. Among 5 components of metabolic syndrome, the criterion of high serum triglyceride was most powerfully associated with serum GGT level in both gender.

CONCLUSIONS

This study shows that serum GGT level was significantly associated with metabolic syndrome even after excluding diabetic adults.

Summary

Citations

Citations to this article as recorded by

Relations between Normal Serum Gamma-glutamyltransferase and Risk Factors of Coronary Heart Diseases according to Age and Gender
Se Young Kwon, Young Ak Na
Korean Journal of Clinical Laboratory Science.2016; 48(1): 22. CrossRef
The Association between Serum Gamma-glutamyltransferase within Normal Range and Risk Factors of Cardiovascular Diseases: Based on the Framingham Risk Score
Hae-Jin Ko, Chang-Su Choi, Chang-Ho Youn, Duk-Hee Lee, Sung-Guk Lee
The Korean Journal of Obesity.2013; 22(1): 21. CrossRef
Letter: The Association between Serum Gamma-glutamyltransferase within Normal Range and Risk Factors of Cardiovascular Diseases: Based on the Framingham Risk Score (Korean J Obes Vol.22 No.1 2013)
Hye Jin Yoo
The Korean Journal of Obesity.2013; 22(4): 259. CrossRef

The association between insulin resistance and Framingham risk score among type 2 diabetes.: Hee Sook Park, Ji Eun Yun, Soo Jin Yoon, Eurin Cho, Kyung A Ahn, Seok Won Park, Chul Woo Ahn, Dae Jung Kim, Young Duk Song, Young Ju Choi, Mi Ae Cho, Eun Jig Lee, Kap Bum Huh, Sun Ha Jee; Korean J Epidemiol. 2007;29(1):46-58.

65,535 View
35 Download

Abstract PDF: Abstract
BACKGROUND
AND PURPOSE: Insulin resistance has been known to be associated with the risk of cardiovascular diseases. However, the relationship with Framingham risk score among type 2 diabetes has not been well known. We investigated the relationship between insulin resistance (IR) and the Framingham risk score(FRS) among type 2 diabetes in Korea.
METHODS
We estimated the 5-year risk of ischemic heart disease(IHD) based on Framingham equation among 1,941 diabetes patients(1,294 men and 647 women), who visited Huh's clinic, enrolled from January 2003 to June 2006. IR, which was measured by insulin tolerance test (ITT), was divided into five groups(Q1 to Q5). High risk of IHD was defined as upper 10 percentile of FRS. Multivariate regression and logistic regression models were used to see independent association of higher quintiles of IR level, compared with lowest quintile(Q1) for the risk of IHD.
RESULTS
Mean (+/-standard deviation) 5-year FRS of study subjects were 8.40%(+/-6.89) for men and 5.92%(+/-5.23) for women. There were significant correlation between IR, body mass index, HbA1C, fasting glucose, triglyceride, LDL-cholesterol, C-peptide and FRS in both men and women. After adjusting for triglyceride, LDL-cholesterol, C-peptide, multivariate regression model analysis showed that IR was independently associated with the FRS. A positive association between IR and high risk of IHD was observed in men: highest versus lowest quintile of IR (odds ratio 5.45 in men and 4.71 in women).
CONCLUSION
Increased IR level was independently associated with risk of IHD measured by FRS among type 2 diabetes in Korea.; Summary

Risk Factors of Impaired Fasting Glucose and Type 2 Diabetes Mellitus: Using Datamining.: Jongseon Ryu, Soonduck Kim, Jongsoon Park, Jesuk Lee; Korean J Epidemiol. 2006;28(2):138-151.

65,535 View
35 Download

Abstract PDF: Abstract
PURPOSE
This study aimed to contribute to overall public health by examining the prevalence rates of impaired fasting blood glucose and type 2 diabetes mellitus and developing a model to predict high risk factors for impaired fasting blood glucose and type 2 diabetes mellitus.
METHODS
The 1998 Public Health Nutrition Survey data was used for this study. Subjects were 7,702 adult at the age of 20 or over. The frequency analysis, chisquared test was performed. A decision tree was utilized to define a model designed to predict high risk factors for impaired fasting glucose and type 2 diabetes mellitus.
RESULTS
The prevalence rates of impaired fasting blood glucose was 10.8% and prevalence rates of type 2 diabetes mellitus was 9.4%. The decision tree analysis exhibited that age was strong factors for impaired fasting blood glucose. HDL cholesterol and kind of economic activities were high risk factors for impaired fasting blood glucose and type 2 diabetes mellitus on those in 20s. BMI, total cholesterol level, marriage status, sex for impaired fasting blood glucose and type 2 diabetes mellitus on those in 30s. The total cholesterol level, drinking and waist size were identified as risk factors on those in 40s. BMI, education level and hypertension seemed to have an impact on those in 50s. The waist size, sex and income had an impact on those in 60s.
CONCLUSIONS
This study underscores the need for the public health infrastructure to improve various health promotion programs for those who have risk factors for impaired fasting blood glucose and type 2 diabetes mellius. The implementation of effective nutrition, workout and anti-drinking programs will boost public health.; Summary

Insulin resistance and cancer.: Hee Jin Kim, Sun Ha Jee; Korean J Epidemiol. 2005;27(2):38-50.

65,535 View
30 Download

Abstract PDF: Abstract
Both obesity and diabetes have been proposed as risk factors of cancer. Obesity may be a more significant health problem, which can increase the risk of cancer and cardiovascular disease, which is the most common cause of death. Insulin resistance and metabolic syndrome are suspected of being correlated with cancer risk. Most studies are carried out on the assumption that obesity, diabetes, cardiovascular disease, and cancer are different conditions. However, they have common risk factors-smoking, obesity, and physical inactivity. Although the pathways leading to these diseases are unknown, we brought a focus into the multi-dimensional pathways instead of single pathogenesis. The interaction between pathogenesis can be thought to start from risk factors, and through pathogenesis, diseases can also lead to a severe cause of death. Epidemic of obesity and diabetes is a significant and growing public health problem. This paper reviewed the evidences of the correlation between insulin resistances and cancer and we explored whether insulin resistance may contribute to carcinogenesis.; Summary

The Dose-response Relationship between Amount of Cigarette Smoking and Blood Lipids and Sugar.: Kang Sook Lee, Hyun Sook Hong, Jin Sook Jeong; Korean J Epidemiol. 1999;21(2):195-204.

9,828 View
17 Download

Abstract PDF: Abstract
PURPOSE
To explore the dose-response relationship between amount of cigarette smoking and blood lipids and sugar METHODS: In this cross-sectional study, we gathered the smoking history by self-administered questionnaire between 1994 and 1998 among 2888 men who visited the Health Promotion Center at St. Mary's Hospital, Seoul.
RESULTS
Adjusted for age, body mass index, the odds ratio of hypercholesterolemia (> or =240 mg/dl) were 2.06 (95% Confident Interval, 1.44-2.94), 2.03(95% CI 1.31-3.11), higher LDL-cholesterol(> or =160 mg/dl) were 2.06(95% CI 1.43-2.98), 2.25(95% CI 1.45-3.45) among group of men who smoked 21-30, over 30 cigarettes per day respectively compared with nonsmokers group. And adjusted for age, body mass index, the odds ratio of lower HDL-cholesterol(<35 mg/dl) were 1.76(95% CI 1.34-2.33), 1.98(95% CI 1.39-2.81), 2.35(95% CI 1.54-3.54), hypertriglyceridemia(> or =200 mg/dl) were 1.93(95% CI 1.47-2.55), 2.57(95% CI 1.82-3.62), 2.80(95% CI 1.86-4.21) among group of men who smoked 11-20, 21-30, over 30 cigarettes per day respectively compared with nonsmokers group. The adjusted odds ratio of diabetes(FBS> or =126 mg/dl) was 1.86(95% CI 1.10-3.06) only among who smoked more than 30 cigarettes compared with nonsmokers.
CONCLUSION
This study showed that there were dose-response relationships betwen amount of cigarette smoking and total cholesterol, HDL-cholesterol, LDL-cholesterol, triglyceride and sugar. It suggested that health promotion program including quitting and decrease of cigarette smoking would be necessary to prevent cardiovascular disease in Korean men.; Summary

The Association of Hyperinsulinemia with Other Cardiovascular Risk Factors.: Kang Sook Lee, Bok Rye Song; Korean J Epidemiol. 1998;20(1):167-177.

9,580 View
5 Download

Abstract PDF: Abstract
BACKGROUND
Hypertension, obesity, non-insulin dependent diabetes(NIDDM), and dyslipidemia are common metaolic disorders that afflict the majority of the elderly who live in Westernized societies. To explore whether the hyperinsulinemia associated with other cardiovascular risk factors in Asian populations such as Koreans.
METHODS
In this cross-sectional study we evaluated the association of hyperinsulinemia with hypertension, obesity, diabetes and hyperlipidemia. Subjects were 600 men and 396 women at least 20 years old who visited the prevention center at St. Mary's Hospital in Seoul, between March and August 1997 for a multiphasic health examination.
RESULTS
In hyperinsulinemia group( >90 percentile of fasting blood insulin 10.01uU/ml in men and 8.54 uU/mlin women), body mass index(BMI), fasting blood sugar, and triglyceride and systolic or diastolic blood pressure were significantly higher than normal insulin goup in both of men and women. The major contributable risk factor to blood insulin concentration was BMI(14% in men, 13% in women). In person with the highest tertile of insulin concentration compared with those in the lowest tertile, age adjusted odds ratio of hypertension, obesity, and hypertriglyceride were 2.22(95% Confidence Interval: 1.38-3.63), 6.96(4.31-11.51), and 4.05(1.88-9.75) in men, and 2.05(95% CI: 1.10-3.86), 4.34(2.39-8.16) and 6.84(1.18-129.40) in women. Age adjusted odds ratio for clusterin of cardiovascular risk factors in the higest tertile of insulin compared with those in lower insulin than that level were 8.74(2.82-29.27) in men and 4.91(1.19-21.79) in women.
CONCLUSION
The hyperinsulinemia was associated with hypertension, obesity, NIDDM and hypertriglyceridemia. Further prospective studies are required to investigate the effects of intervetion to improve insulin sensitivity such as calorie restriction and exercise.; Summary

First
Prev
Page of 1
Next
Last

Search