Skip Navigation
Skip to contents

Epidemiol Health : Epidemiology and Health

OPEN ACCESS
SEARCH
Search
Advanced Search
mobile menu button

Search

Page Path
HOME > Search
3 "So Young Kim"
Filter
Filter
Article category
Keywords
More +
Publication year
Authors
More +
Funded articles
Original Article
Causal effect of fasting serum glucose on atherosclerotic cardiovascular disease: a multivariable Mendelian randomization
Su Hyun Lee, Heejin Kimm, Byung-Wan Lee, Chung Mo Nam, So Young Kim, Sunmi Lee, Sun Ha Jee
Epidemiol Health. 2024;46:e2024096.   Published online December 6, 2024
DOI: https://doi.org/10.4178/epih.e2024096
  • 1,090 View
  • 80 Download
AbstractAbstract AbstractSummary PDF
Abstract
OBJECTIVES
Observational studies have reported that diabetes is a risk factor that increases the risk of atherosclerotic cardiovascular disease (ASCVD). However, the causal relationship remains a matter of debate. This study aimed to analyze the relationship between fasting serum glucose (FSG) and ASCVD.
METHODS
This study used data from the Korean Cancer Prevention Study-II (KCPS-II) Biobank, consisting of 159,844 people recruited with consent from 18 health examination centers from 2004 to 2013. Outcomes were confirmed based on diagnoses on hospital discharge summaries from National Health Insurance System. We used linear and non-linear Mendelian randomization (MR) methods. The outcome data were obtained from KCPS-II, and the exposure data were derived from the Korean Genome Epidemiology Study.
RESULTS
First, a prospective cohort study estimated that for each 10 mg/dL increase in FSG level, the risk of ASCVD increased by 4% (hazard ratio [HR], 1.04; 95% confidence interval [CI], 1.03 to 1.05). Second, the 2-sample MR study showed that every 10 mg/dL increase in FSG influenced the risk of ASCVD (odds ratio [OR], 1.11; 95% CI, 1.04 to 1.18). Third, the multivariable MR study showed that the OR per 10 mg/dL increase in FSG on ASCVD was 1.14 (p<0.001). Similar results were found for a 10 mg/dL increase in FSG and ischemic heart disease (IHD), but a significant relationship with stroke was not found. When performing non-linear MR, a linear relationship was observed between fasting blood sugar and ASCVD, including IHD and stroke.
CONCLUSIONS
FSG showed a linear and causal association with IHD, but not with stroke.
Summary
Korean summary
그동안 당뇨병이 심뇌혈관질환 발생에 위험요인이라는 역학적인 관찰연구는 많이 발표되었지만, 이러한 관련성에 대한 인과적 관련성에 대부분 연구는 서양인을 대상으로 발표되었고, 한국인 자료를 통해 발표된 적은 없었다. 이 연구는 관찰연구의 제한점으로 부각되는 혼란변수와 측정오류에 덜 영향을 받는 새로운 방법론으로써 다변수 멘델리언 무작위화 방법을 사용하여 공복혈당과 심뇌혈관질환의 인과성을 분석하였다. 분석결과, 공복혈당은 허혈성 심질환 발생위험에 인과적인을 관련성을 보였고 뇌졸중에 대해서는 인과적이지 않았다.
Key Message
Over the years, numerous epidemiological observational studies have reported that diabetes is a risk factor for cardiovascular and cerebrovascular diseases. However, most of these studies examining this association were conducted on Western populations, and no studies have been published using Korean data. This study employed a new methodology—multivariable Mendelian randomization—which is less affected by confounding factors and measurement errors, often highlighted as limitations of observational studies, to analyze the causal relationship between fasting glucose levels and cardiovascular and cerebrovascular diseases. The analysis revealed a causal relationship between fasting glucose levels and the risk of ischemic heart disease, while no causal association was observed with stroke.
Special Article
The Korea National Disability Registration System
Miso Kim, Wonyoung Jung, So Young Kim, Jong Hyock Park, Dong Wook Shin
Epidemiol Health. 2023;45:e2023053.   Published online May 11, 2023
DOI: https://doi.org/10.4178/epih.e2023053
  • 13,554 View
  • 299 Download
  • 29 Web of Science
  • 32 Crossref
AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
The Korea National Disability Registration System (KNDRS) was established in 1989 to provide social welfare benefits based on predefined criteria for disability registration and an objective medical assessment using a disability grading system. Disability registration requires (1) a medical examination by a qualified specialist physician and (2) a medical advisory meeting to review the degree of disability. Medical institutions and specialists for the diagnosis of disabilities are legally stipulated, and medical records for a specified period are required to support the diagnosis. The number of disability types has gradually expanded, and 15 disability types have been legally defined. As of 2021, 2.645 million people were registered as disabled, accounting for approximately 5.1% of the total population. Among the 15 disability types, disabilities of the extremities account for the largest proportion (45.1%). Previous studies have investigated the epidemiology of disabilities using data from the KNDRS, combined predominantly with data from the National Health Insurance Research Database (NHIRD). Korea has a mandatory public health insurance system that covers the entire Korean population, and the National Health Insurance Services manages all eligibility information, including disability types and severity ratings. In short, the KNDRS-NHIRD is a significant data resource for research on the epidemiology of disabilities.
Summary
Korean summary
한국에서는 장애의 유형과 장애 유형별 장애정도를 장애인 복지법에서 규정하고 있다. 우리는 한국의 장애등록제도의 역사와 장애등록절차 그리고 장애유형별 통계 현황에 대해서 다루고자 한다.
Key Message
In Korea, the types and severity levels of disabilities are legally defined by the Korea National Disability Registration System (KNDRS). We address the history of the KNDRS, disability registration procedures, and current statistics.

Citations

Citations to this article as recorded by  
  • Longitudinal analysis of anxiety and sleep disorders in the Korean population with disabilities, from 2006 to 2017: Incidence, prevalence, and association with disability type and severity
    H.-Y. Lee, K.E. Yeob, S.Y. Kim, Y.Y. Kim, J.H. Park
    Journal of Affective Disorders.2025; 369: 135.     CrossRef
  • Association between Age-Related Macular Degeneration with Visual Disability and Risk of Dementia: A Nationwide Cohort Study
    Ki Young Son, Yong-Jun Choi, Bongseong Kim, Kyungdo Han, Sungsoon Hwang, Wonyoung Jung, Dong Wook Shin, Dong Hui Lim
    Journal of the American Medical Directors Association.2025; 26(2): 105392.     CrossRef
  • Increased risk of type 2 diabetes after traumatic amputation: a nationwide retrospective cohort study
    Jung Eun Yoo, Dagyeong Lee, Bongseong Kim, Won Hyuk Chang, Sang-Man Jin, Kyungdo Han, Dong Wook Shin
    Frontiers in Endocrinology.2025;[Epub]     CrossRef
  • Increased Risk of End-Stage Kidney Disease After Traumatic Amputation: Nationwide Cohort Study
    Jung Eun Yoo, Bongseong Kim, Won Hyuk Chang, Kyungho Lee, Hye Ryoun Jang, Kyungdo Han, Dong Wook Shin
    Healthcare.2025; 13(1): 80.     CrossRef
  • The link between disability and social participation revisited: Heterogeneity by type of social participation and by socioeconomic status
    Jinho Kim, Gum-Ryeong Park, Eun Ha Namkung
    Disability and Health Journal.2024; 17(2): 101543.     CrossRef
  • Increased Risk of Dementia Following a Diagnosis of Hearing Impairment: A South Korean Nationwide Cohort Study
    Minah Park, Sung-In Jang, Kyungduk Hurh, Eun-Cheol Park, Seung Hoon Kim
    Journal of Alzheimer's Disease.2024; 97(2): 679.     CrossRef
  • Risk of fracture among patients with spinal cord injury: A nationwide cohort study in South Korea
    Seonghye Kim, Bongseong Kim, Kyung-Do Han, Junhee Park, Jung Eun Yoo, Hea Lim Choi, Won Hyuk Chang, In Young Cho, Dong Wook Shin
    Bone.2024; 183: 117093.     CrossRef
  • Desafios para inclusão de escolares com deficiência em um estado do brasileiro
    Paola Regina Martins Bruno, Graziane Pacini Rodrigues, Damarys Paula Alves Alvim, Francisco Winter dos Santos Figueiredo, Janeisi de Lima Meira, Andreia de Bem Machado, Gabriel Martins Cabral, Fernando Rodrigues Peixoto Quaresma
    Cuadernos de Educación y Desarrollo.2024; 16(4): e3840.     CrossRef
  • Korean autistic persons facing systemic stigmatization from middle education schools: daily survival on the edge as a puppet
    Wn-ho Yoon, JaeKyung Seo, Cheolung Je
    Frontiers in Psychiatry.2024;[Epub]     CrossRef
  • Disability acceptance and depressive symptoms: the moderating role of social support
    Gum-Ryeong Park, Sujeong Park, Jinho Kim
    Disability and Rehabilitation.2024; 46(26): 6424.     CrossRef
  • Impact of a Service-Learning Program Using Soccer Training on the Emotional and Behavioral Problems of Children with Developmental Disabilities
    Huan Meng, Yonghwan Kim, Kyujin Lee
    Children.2024; 11(4): 467.     CrossRef
  • Risk of Heart Disease in Patients With Amputation: A Nationwide Cohort Study in South Korea
    Hea Lim Choi, Jung Eun Yoo, Miso Kim, Bongsung Kim, Junhee Park, Won Hyuk Chang, Heesun Lee, Kyungdo Han, Dong Wook Shin
    Journal of the American Heart Association.2024;[Epub]     CrossRef
  • Fracture Risk Among Stroke Survivors According to Poststroke Disability Status and Stroke Type
    Dagyeong Lee, In Young Cho, Won Hyuk Chang, Jung Eun Yoo, Hea Lim Choi, Junhee Park, Dong Wook Shin, Kyungdo Han
    Stroke.2024; 55(6): 1498.     CrossRef
  • Disparities in the diagnosis and treatment of colorectal cancer among patients with disabilities
    Ki Bae Kim, Dong Wook Shin, Kyoung Eun Yeob, So Young Kim, Joung-Ho Han, Seon Mee Park, Jong Heon Park, Jong Hyock Park
    World Journal of Gastrointestinal Oncology.2024; 16(7): 2925.     CrossRef
  • Increased Risk of Fracture after Traumatic Amputation: A Nationwide Retrospective Cohort Study
    Hyeonjin Cho, Junhee Park, Bongseong Kim, Kyungdo Han, Hea Lim Choi, Dong Wook Shin
    Healthcare.2024; 12(13): 1362.     CrossRef
  • Trends in Physiotherapy Interventions and Medical Costs for Parkinson’s Disease in South Korea, 2011–2020
    Dong-Woo Ryu, Jinse Park, Myung Jun Lee, Dallah Yoo, Sang-Myung Cheon
    Journal of Movement Disorders.2024; 17(3): 270.     CrossRef
  • COVID-19 and Neurodevelopmental Delays in Early Childhood: A Longitudinal Analysis of Developmental Outcomes in Korean Children
    Youn Young Choi, Kyung-Shin Lee, Seul Gi Park, You Sun Kim, Jeehye Lee, Ho Kyung Sung, Myoung-hee Kim
    Journal of Korean Medical Science.2024;[Epub]     CrossRef
  • Risk of depression in amyotrophic lateral sclerosis: A nationwide cohort study in South Korea
    Soonwook Kwon, Bongseong Kim, Kyung-Do Han, Wonyoung Jung, Eun Bin Cho, Dong Wook Shin, Ju-Hong Min
    Journal of Psychiatric Research.2024; 178: 414.     CrossRef
  • Association between glycemic status and all-cause mortality among individuals with dementia: a nationwide cohort study
    Youn Huh, Kye-Yeung Park, Kyungdo Han, Jin-Hyung Jung, Yoon Jeong Cho, Hye Soon Park, Ga Eun Nam, Soo Lim
    Alzheimer's Research & Therapy.2024;[Epub]     CrossRef
  • The Association between Healthcare Satisfaction and Social Support and Stress, Depression, and Life Satisfaction in Female Caregivers: The Moderating Role of Dependence of a Sick Child
    Jadranka Pavić, Mateja Krznar, Snježana Čukljek, Biserka Sedić, Štefanija Ozimec Vulinec, Irena Kovačević
    International Journal of Environmental Research and Public Health.2024; 21(9): 1245.     CrossRef
  • Comparison of the risk of noise-induced hearing loss between male police officers and male non-police officers: a nationwide cohort study using propensity score matching in South Korea
    Woo-Ri Lee, Kyu-Tae Han, Ki-Bong Yoo, Jin-Ha Yoon
    BMC Public Health.2024;[Epub]     CrossRef
  • Retinal Vascular Occlusions After COVID-19 Vaccination in South Korea: A Nation-Wide Population-Based Study
    Yeji Kim, Kyungdo Han, Jae Hui Kim
    Ophthalmic Epidemiology.2024; : 1.     CrossRef
  • Short-Term and Long-Term Risk of Diabetes Mellitus among Patients with Spinal Cord Injury: A Nationwide Retrospective Cohort Study
    Seonghye Kim, Kyung-Do Han, Bongseong Kim, Ju-Hong Min, Won Hyuk Chang, In Young Cho, Dong Wook Shin
    Healthcare.2024; 12(18): 1859.     CrossRef
  • Intellectual disabilities and risk of cardiovascular diseases: A population-based cohort study
    In Young Cho, Hye Yeon Koo, Yoo Jin Um, Yong-Moon Mark Park, Kyung Mee Kim, Chung Eun Lee, Kyungdo Han
    Disability and Health Journal.2024; : 101754.     CrossRef
  • Widening disparities in the national prevalence of diabetes mellitus for people with disabilities in South Korea
    I. Hwang, S.Y. Kim, Y.Y. Kim, J.H. Park
    Public Health.2024; 226: 173.     CrossRef
  • Increased Risk of Myocardial Infarction, Heart Failure, and Atrial Fibrillation After Spinal Cord Injury
    Jung Eun Yoo, Miso Kim, Bongseong Kim, Heesun Lee, Won Hyuk Chang, Jeehyun Yoo, Kyungdo Han, Dong Wook Shin
    Journal of the American College of Cardiology.2024; 83(7): 741.     CrossRef
  • Beyond the Stereotype: Exploring Monetary Donations and Volunteerism Among People With Disabilities
    Jonghwa Lee, Youngeun Son, Ha-Neul Kim
    Nonprofit and Voluntary Sector Quarterly.2024;[Epub]     CrossRef
  • Elevated risk of end-stage kidney disease in stroke patients: A population-based observational study
    Sohyun Chun, Kyungdo Han, Bongseong Kim, Dagyeong Lee, In Young Cho, Hea Lim Choi, Jun Hee Park, Junseok Jeon, Hye Ryoun Jang, Dong Wook Shin
    International Journal of Stroke.2024;[Epub]     CrossRef
  • Caregivers' Awareness and Behavior Impacting the Oral Health of Pediatric and Adolescent Patients with Disabilities
    Haesong Kang, Namki Choi, Seonmi Kim
    THE JOURNAL OF THE KOREAN ACADEMY OF PEDTATRIC DENTISTRY.2024; 51(4): 459.     CrossRef
  • Longitudinal association between disability and suicide mortality in Republic of Korea
    Hwa-Young Lee, Dong Wook Shin, Kyung-Do Han, Ichiro Kawachi
    International Journal of Epidemiology.2024;[Epub]     CrossRef
  • Increased risk of Parkinson's disease amongst patients with age‐related macular degeneration and visual disability: A nationwide cohort study
    Je Moon Yoon, Dong Hui Lim, Jinyoung Youn, Kyungdo Han, Bong Sung Kim, Wonyoung Jung, Yohwan Yeo, Dong Wook Shin, Don‐Il Ham
    European Journal of Neurology.2023; 30(9): 2641.     CrossRef
  • Increased risk of myocardial infarction in amyotrophic lateral sclerosis: A nationwide cohort study in South Korea
    Soonwook Kwon, Bongseong Kim, Kyung-Do Han, Wonyoung Jung, Eun Bin Cho, Jeong Hoon Yang, Dong Wook Shin, Ju-Hong Min
    Journal of the Neurological Sciences.2023; 454: 120829.     CrossRef
Original Article
Nationwide trends in the incidence of tuberculosis among people with disabilities in Korea: a nationwide serial cross-sectional study
Jinsoo Min, So Young Kim, Jong Eun Park, Yeon Yong Kim, Jong Hyock Park
Epidemiol Health. 2022;44:e2022098.   Published online October 28, 2022
DOI: https://doi.org/10.4178/epih.e2022098
  • 6,576 View
  • 135 Download
  • 4 Web of Science
  • 4 Crossref
AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
OBJECTIVES
Studies on the association between disabilities and tuberculosis (TB) are scarce. We aimed to assess the risk of active TB disease among people with disabilities.
METHODS
We conducted a nationwide serial cross-sectional study using national registry linkage databases from 2008 to 2017. The crude and age-standardized and sex-standardized incidence rates of TB were analyzed for each year according to the presence, type, and severity of disabilities. The crude incidence rate and odds of developing TB disease were examined with a multivariable logistic regression model using data from 2017.
RESULTS
The overall incidence of active TB decreased between 2008 and 2017. The age- and sex-standardized incidence rates of TB disease among people with disabilities were significantly higher than among those without disabilities throughout all observed years (p<0.001). As of 2017, the population with disabilities had a higher crude incidence rate of active TB disease than that without disabilities (119.9/100,000 vs. 48.5/100,000 person-years, p<0.001), regardless of sex, income level, and place of residence. Compared to those without disabilities, those with disabilities had higher odds of active TB (adjusted odds ratio [aOR], 1.19; 95% confidence interval [CI], 1.15 to 1.24). Individuals with mental disabilities (aOR, 1.51; 95% CI, 1.24 to1.84) had the highest odds of active TB incidence, followed by those with developmental disabilities (aOR, 1.30; 95% CI, 1.09 to 1.55).
CONCLUSIONS
People with disabilities are at a greater risk of developing TB disease. Active screening and care for TB cases would be beneficial for people with disabilities.
Summary
Korean summary
장애가 있는 사람은 이차적 건강 문제가 발생할 가능성이 더 높고 그들의 건강결정요인은 결핵 발생 위험 요인과 겹친다. 장애인은 비장애인에 비해 연령과 성별에 관계없이 활동성 결핵 발병률이 현저히 높았으며, 장애 유형 중 정신장애와 발달장애가 결핵에 더 취약한 것으로 나타났다. 장애인과 같이 결핵 감염 위험이 있는 취약계층을 파악하고 이들에게 결핵진단 및 항결핵치료의 어려움을 극복할 수 있도록 다학제적 지원을 제공하는 것이 중요하겠다.
Key Message
People with disabilities are more likely to develop secondary health conditions and their social determinants of health overlap with the risk factors for developing TB disease. We found that compared to people without disabilities, a markedly higher incidence of active TB disease among people with disabilities regardless of age and sex, and mental and developmental disabilities among types of disability were more prone to TB disease. It is critical to identify the vulnerable populations, such as people with disabilities, at risk of developing TB infection and provide them with multidisciplinary support to overcome any barriers during TB diagnosis and anti-TB treatment.

Citations

Citations to this article as recorded by  
  • HIV knowledge and access to testing for people with and without disabilities in low‐ and middle‐income countries: evidence from 37 Multiple Indicator Cluster Surveys
    Sara Rotenberg, Shanquan Chen, Jill Hanass‐Hancock, Calum Davey, Lena Morgon Banks, Hannah Kuper
    Journal of the International AIDS Society.2024;[Epub]     CrossRef
  • The Korea National Disability Registration System
    Miso Kim, Wonyoung Jung, So Young Kim, Jong Hyock Park, Dong Wook Shin
    Epidemiology and Health.2023; 45: e2023053.     CrossRef
  • Nationwide Trends in Osteoporosis in Koreans With Disabilities From 2008 to 2017
    Ji Hyoun Kim, So Young Kim, Jong Eun Park, Hyo Jong Kim, Hyun Jeong Jeon, Yeon Yong Kim, Jong‐Hyock Park
    JBMR Plus.2023;[Epub]     CrossRef
  • Growing disparity in the prevalence of chronic obstructive pulmonary disease between people with and without disabilities: a Korean nationwide serial cross-sectional study
    Jinsoo Min, Jong Eun Park, So Young Kim, Yeon Yong Kim, Jong Hyock Park
    Scientific Reports.2023;[Epub]     CrossRef
Epidemiol Health : Epidemiology and Health
© Korean Society of Epidemiology.
TOP