Skip Navigation
Skip to contents

Epidemiol Health : Epidemiology and Health

OPEN ACCESS
SEARCH
Search

Author index

Page Path
HOME > Browse articles > Author index
Search
Maryam Tahmasebi Birgani 1 Article
Oral colonization by Candida species and associated factors in HIV-infected patients in Ahvaz, southwest Iran
Elham Aboualigalehdari, Maryam Tahmasebi Birgani, Mahnaz Fatahinia, Mehran Hosseinzadeh
Epidemiol Health. 2020;42:e2020033.   Published online May 24, 2020
DOI: https://doi.org/10.4178/epih.e2020033
  • 15,231 View
  • 173 Download
  • 14 Web of Science
  • 11 Crossref
AbstractAbstract PDF
Abstract
Objectives
Oropharyngeal candidiasis is one of the most common opportunistic fungal infections among human immunodeficiency virus (HIV)-infected individuals. The most common cause is <i>Candida albicans</i>, followed by non-<i>albicans Candida</i>. This study aimed to identify colonized <i>Candida</i> species in HIV-infected patients from Ahvaz, Iran. Additionally, the relationships between immunity-related factors, lifestyle, and colonization of <i>Candida</i> spp. were studied.
Methods
Oral swabs were taken from 201 HIV-positive patients referred for consultations at the Behavioral Modification Center. Oral <i>Candida</i> colonization was detected using culture-based and molecular assays. Data were assessed by descriptive statistics and analyzed to investigate the correlation between <i>Candida</i> colonization and various factors, including the CD4<sup>+</sup> cell count and viral load.
Results
It was found that 43.8% of patients were positive for <i>Candida</i>. The most common species was C. <i>albicans</i> (48.0%), followed by non-<i>albicans Candida</i> isolates, including <i>C. dubliniensis, C. glabrata, C. tropicalis, C. parapsilosis, C. guilliermondii, C. kefyr</i>, and <i>C. krusei.</i> Colonization of <i>Candida</i> spp. in patients was associated with a CD4 count ≤200 cells/mm<sup>3</sup> (odds ratio [OR], 4.62; p<0.05), history of shared injections (OR, 6.96; p<0.001), and sex (OR, 3.59; p<0.05).
Conclusions
The results of this study showed that C. <i>albicans</i> was the dominant pathogen. The risk factors for colonization of <i>Candida</i> spp. were a CD4 count ≤ 200/mm<sup>3</sup> , a history of shared injections, and sex. Other factors with potential relationships include viral load, age, and opportunistic infections, but further investigations are needed.
Summary

Citations

Citations to this article as recorded by  
  • Antifungal Susceptibility and Candida sp. Biofilm Production in Clinical Isolates of HIV-Positive Brazilian Patients under HAART Therapy
    Anelise Maria Costa Vasconcelos Alves, Érika Helena Salles de Brito, Márcio Flávio Moura de Araújo, Juliana Jales de Hollanda Celestino, Ana Caroline Rocha de Melo Leite, Gabriela Silva Cruz, Nuno Filipe Azevedo, Célia Fortuna Rodrigues
    Biomedicines.2024; 12(2): 310.     CrossRef
  • Exploring the diversity of uncommon oral yeast species and associated risk factors among substance abusers in southwestern Iran
    Aynaz Ghojoghi, Sadegh Khodavaisy, Ali Zarei Mahmoudabadi, Eisa Nazar, Mahnaz Fatahinia
    Scientific Reports.2024;[Epub]     CrossRef
  • Recuento de linfocitos CD4, carga viral y colonización oral por Candida en personas viviendo con VIH/SIDA
    Esperanza Gissela Vargas-Díaz, Graciela Albino Cornejo, Hans Ramón Quiroz-Ruiz
    Gaceta Médica Boliviana.2023; 46(1): 18.     CrossRef
  • Low level of antifungal resistance inCandidaspecies recovered from Iranian HIV-associated oral infection
    Maryam Erfaninejad, Ali Zarei Mahmoudabadi, Elham Maraghi, Mohammad Hashemzadeh, Mahnaz Fatahinia
    Letters in Applied Microbiology.2023;[Epub]     CrossRef
  • Epidemiology, prevalence, and associated factors of oral candidiasis in HIV patients from southwest Iran in post-highly active antiretroviral therapy era
    Maryam Erfaninejad, Ali Zarei Mahmoudabadi, Elham Maraghi, Mohammad Hashemzadeh, Mahnaz Fatahinia
    Frontiers in Microbiology.2022;[Epub]     CrossRef
  • Meyerozyma guilliermondii species complex: review of current epidemiology, antifungal resistance, and mechanisms
    Reza Ghasemi, Ensieh Lotfali, Kamran Rezaei, Seyed Ataollah Madinehzad, Mahdi Falah Tafti, Nikta Aliabadi, Ebrahim Kouhsari, Mahsa Fattahi
    Brazilian Journal of Microbiology.2022; 53(4): 1761.     CrossRef
  • HIV-infected patients rarely develop invasive fungal diseases under good immune reconstitution after ART regardless high prevalence of pathogenic filamentous fungi carriage in nasopharynx/oropharynx
    Xiaoman Chen, Yi Cao, Meijun Chen, Haodi Wang, Peishan Du, Hong Li, Huolin Zhong, Quanmin Li, Santao Zhao, Zhenjiang Yao, Wanshan Chen, Weiping Cai, Xiaoping Tang, Linghua Li
    Frontiers in Microbiology.2022;[Epub]     CrossRef
  • Neglected mycobiome in HIV infection: Alterations, common fungal diseases and antifungal immunity
    Shuang Li, Xiaodong Yang, Christiane Moog, Hao Wu, Bin Su, Tong Zhang
    Frontiers in Immunology.2022;[Epub]     CrossRef
  • Identification & Correlation of Candida Strains with CD4+ Count Among HIV Patients on HAART and Evaluation of In-Vitro Susceptibility to Fluconazole and Voriconazole
    Naidu Harika, Koduri Sridevi, Buduru Krishnaveni, Nalli Prasanth Kumar, Gutta Mounika, Adari Devi Naga Deepika
    Journal of Indian Academy of Oral Medicine and Radiology.2022; 34(1): 38.     CrossRef
  • Update of the list of QPS‐recommended biological agents intentionally added to food or feed as notified to EFSA 13: suitability of taxonomic units notified to EFSA until September 2020
    Kostas Koutsoumanis, Ana Allende, Avelino Alvarez‐Ordóñez, Declan Bolton, Sara Bover‐Cid, Marianne Chemaly, Robert Davies, Alessandra De Cesare, Friederike Hilbert, Roland Lindqvist, Maarten Nauta, Luisa Peixe, Giuseppe Ru, Marion Simmons, Panagiotis Skan
    EFSA Journal.2021;[Epub]     CrossRef
  • Transcription Factors of CAT1, EFG1, and BCR1 Are Effective in Persister Cells of Candida albicans-Associated HIV-Positive and Chemotherapy Patients
    Elham Aboualigalehdari, Maryam Tahmasebi Birgani, Mahnaz Fatahinia, Mehran Hosseinzadeh
    Frontiers in Microbiology.2021;[Epub]     CrossRef

Epidemiol Health : Epidemiology and Health
TOP