Skip Navigation
Skip to contents

Epidemiol Health : Epidemiology and Health

OPEN ACCESS
SEARCH
Search

Author index

Page Path
HOME > Browse articles > Author index
Search
Jae-Hyun Park 2 Articles
Korea Seroprevalence Study of Monitoring of SARS-COV-2 Antibody Retention and Transmission (K-SEROSMART): findings from national representative sample
Jina Han, Hye Jin Baek, Eunbi Noh, Kyuhyun Yoon, Jung Ae Kim, Sukhyun Ryu, Kay O Lee, No Yai Park, Eunok Jung, Sangil Kim, Hyukmin Lee, Yoo-Sung Hwang, Jaehun Jung, Hun Jae Lee, Sung-il Cho, Sangcheol Oh, Migyeong Kim, Chang-Mo Oh, Byengchul Yu, Young-Seoub Hong, Keonyeop Kim, Sun Jae Jung, Mi Ah Han, Moo-Sik Lee, Jung-Jeung Lee, Young Hwangbo, Hyeon Woo Yim, Yu-Mi Kim, Joongyub Lee, Weon-Young Lee, Jae-Hyun Park, Sungsoo Oh, Heui Sug Jo, Hyeongsu Kim, Gilwon Kang, Hae-Sung Nam, Ju-Hyung Lee, Gyung-Jae Oh, Min-Ho Shin, Soyeon Ryu, Tae-Yoon Hwang, Soon-Woo Park, Sang Kyu Kim, Roma Seol, Ki-Soo Park, Su Young Kim, Jun-wook Kwon, Sung Soon Kim, Byoungguk Kim, June-Woo Lee, Eun Young Jang, Ah-Ra Kim, Jeonghyun Nam, The Korea Community Health Survey Group, Soon Young Lee, Dong-Hyun Kim
Epidemiol Health. 2023;45:e2023075.   Published online August 17, 2023
DOI: https://doi.org/10.4178/epih.e2023075
  • 7,991 View
  • 222 Download
  • 4 Web of Science
  • 4 Crossref
AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
OBJECTIVES
We estimated the population prevalence of antibodies to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), including unreported infections, through a Korea Seroprevalence Study of Monitoring of SARS-CoV-2 Antibody Retention and Transmission (K-SEROSMART) in 258 communities throughout Korea.
METHODS
In August 2022, a survey was conducted among 10,000 household members aged 5 years and older, in households selected through two stage probability random sampling. During face-to-face household interviews, participants self-reported their health status, COVID-19 diagnosis and vaccination history, and general characteristics. Subsequently, participants visited a community health center or medical clinic for blood sampling. Blood samples were analyzed for the presence of antibodies to spike proteins (anti-S) and antibodies to nucleocapsid proteins (anti-N) SARS-CoV-2 proteins using an electrochemiluminescence immunoassay. To estimate the population prevalence, the PROC SURVEYMEANS statistical procedure was employed, with weighting to reflect demographic data from July 2022.
RESULTS
In total, 9,945 individuals from 5,041 households were surveyed across 258 communities, representing all basic local governments in Korea. The overall population-adjusted prevalence rates of anti-S and anti-N were 97.6% and 57.1%, respectively. Since the Korea Disease Control and Prevention Agency has reported a cumulative incidence of confirmed cases of 37.8% through July 31, 2022, the proportion of unreported infections among all COVID-19 infection was suggested to be 33.9%.
CONCLUSIONS
The K-SEROSMART represents the first nationwide, community-based seroepidemiologic survey of COVID-19, confirming that most individuals possess antibodies to SARS-CoV-2 and that a significant number of unreported cases existed. Furthermore, this study lays the foundation for a surveillance system to continuously monitor transmission at the community level and the response to COVID-19.
Summary
Korean summary
인구집단을 기반으로 하여 대표성 있는 표본을 추출하여 COVID-19 항체유병률 조사를 전국적으로 수행함으로 지역사회 단위에서 지속적으로 모니터링할 수 있는 COVID-19 감시체계 구축의 기반을 마련하였다. 2022년 8월 우리나라 국민의 대부분이 COVID-19에 대한 항체를 보유하고 있었고 인구 3명 중 1명은 미확진 감염자로 추정되었다.
Key Message
The K-SEROSMART represents the first nationwide, community-based seroepidemiologic survey of COVID-19. In August 2022, most of the Korean people had antibodies to COVID-19, and one in three people was estimated to have an unreported infection. This study lays the foundation for a surveillance system to continuously monitor transmission at the community level and the response to COVID-19.

Citations

Citations to this article as recorded by  
  • Infection-mediated immune response in SARS-CoV-2 breakthrough infection and implications for next-generation COVID-19 vaccine development
    Sho Miyamoto, Tadaki Suzuki
    Vaccine.2024; 42(6): 1401.     CrossRef
  • Changes in the intrinsic severity of severe acute respiratory syndrome coronavirus 2 according to the emerging variant: a nationwide study from February 2020 to June 2022, including comparison with vaccinated populations
    Boyeong Ryu, Eunjeong Shin, Dong Hwi Kim, HyunJu Lee, So Young Choi, Seong-Sun Kim, Il-Hwan Kim, Eun-Jin Kim, Sangwon Lee, Jaehyun Jeon, Donghyok Kwon, Sungil Cho
    BMC Infectious Diseases.2024;[Epub]     CrossRef
  • Seroprevalence of SARS-CoV-2 infection in pediatric patients in a tertiary care hospital setting
    Ploy Pattanakitsakul, Chanya Pongpatipat, Chavachol Setthaudom, Mongkol Kunakorn, Thiantip Sahakijpicharn, Anannit Visudtibhan, Nopporn Apiwattanakul, Surapat Assawawiroonhakarn, Uthen Pandee, Chonnamet Techasaensiri, Sophida Boonsathorn, Sujittra Chaisav
    PLOS ONE.2024; 19(9): e0310860.     CrossRef
  • Realistic Estimation of COVID-19 Infection by Seroprevalence Surveillance of SARS-CoV-2 Antibodies: An Experience From Korea Metropolitan Area From January to May 2022
    In Hwa Jeong, Jong-Hun Kim, Min-Jung Kwon, Jayoung Kim, Hee Jin Huh, Byoungguk Kim, Junewoo Lee, Jeong-hyun Nam, Eun-Suk Kang
    Journal of Korean Medical Science.2024;[Epub]     CrossRef
Burden of Disease of Multiple Sclerosis in Korea
Soo-Eun Chung, Hae-Kwan Cheong, Jae-Hyun Park, Ho Jin Kim
Epidemiol Health. 2012;34:e2012008.   Published online November 30, 2012
DOI: https://doi.org/10.4178/epih/e2012008
  • 22,243 View
  • 156 Download
  • 20 Crossref
AbstractAbstract PDF
Abstract
<sec><title>OBJECTIVES</title><p>Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system. There are few reports on the burden of disease of MS, worldwide. The authors aim to estimate burden of disease and estimate the epidemiologic indexes of MS in Korea using available epidemiologic data.</p></sec><sec><title>METHODS</title><p>Epidemiologic indexes were computed using DISMOD II software based on prevalence from nationwide survey, incidence estimated from extrapolation, mortality from National Statistics Office, and duration of disease from literature as input indexes. We calculated disability-adjusted life year (DALY) as a measure of premature mortality and disability, equivalent to years of healthy life lost due to a given condition.</p></sec><sec><title>RESULTS</title><p>The incidence of MS in Korea was 0.1 per 100,000, higher in female than in male. The highest incidence was estimated in the age group between 35 and 44 years in male and age group between 25 and 29 years in female. Total burden of disease of MS was 1,394 DALY, comprised of 292 (21%) years of life lost and 1,101 (79%) years lived with disability. The mean age at onset of MS was 33 years old in men and 32 years old in female. Estimated duration of disease was 35 years in men and 40 years in female. Most of the DALY of MS occurred in the adult population between 25 and 54 years of age.</p></sec><sec><title>CONCLUSION</title><p>Although MS is a rare disease in Korea, most of the DALY arises from young people, which results in a major financial burden on the patient, family, health system and society.</p></sec>
Summary

Citations

Citations to this article as recorded by  
  • A systematic review of studies that estimated the burden of chronic non-communicable rare diseases using disability-adjusted life years
    Claudia Cruz Oliveira, Periklis Charalampous, Julien Delaye, Diana Alecsandra Grad, Pavel Kolkhir, Enkeleint A. Mechili, Brigid Unim, Brecht Devleesschauwer, Juanita A. Haagsma
    Orphanet Journal of Rare Diseases.2024;[Epub]     CrossRef
  • Incidencia y prevalencia de la esclerosis múltiple en China y países asiáticos
    G.X. Zhang, A. Carrillo-Vico, W.T. Zhang, S.S. Gao, G. Izquierdo Ayuso
    Neurología.2023; 38(3): 159.     CrossRef
  • Incidence and prevalence of multiple sclerosis in China and other Asian countries
    G.X. Zhang, A. Carrillo-Vico, W.T. Zhang, S.S. Gao, G. Izquierdo Ayuso
    Neurología (English Edition).2023; 38(3): 159.     CrossRef
  • Hypophosphatemic Rickets in Colombia: A Prevalence-Estimation Model in Rare Diseases. 2018
    Jancy Andrea Huertas-Quintero, Natalia Losada-Trujillo, Diego Alberto Cuellar-Ortiz, Harvy Mauricio Velasco-Parra
    The Lancet Regional Health - Americas.2022; 7: 100131.     CrossRef
  • A multicenter study to evaluate the disease burden and health economics of inpatients with multiple sclerosis in China
    Tan Guojun, Xu Yan, Wang Weizhi, Wang Lihua, Li Chunyang, Zhang Xinghu, Zhou Hongyu, Dong Huiqing, Zhang Meini, Jin Tao, Yang Huan, Cui Liying, Guo Li
    Multiple Sclerosis and Related Disorders.2022; 60: 103732.     CrossRef
  • The analysis of dynamic gene expression patterns in peripheral blood of multiple sclerosis patients indicates possible diagnostic and prognostic biomarkers
    Rabat Razia, Fazeel Majeed, Rehab Amin, Shahid Mukhtar, Khalid Mehmood, Deeba Noreen Baig
    Molecular Immunology.2022; 147: 147.     CrossRef
  • Identification of blood-derived candidate gene markers and a new 7-gene diagnostic model for multiple sclerosis
    Xin Chen, Huiqing Hou, Huimin Qiao, Haolong Fan, Tianyi Zhao, Mei Dong
    Biological Research.2021;[Epub]     CrossRef
  • Epidemiology, treatment patterns and healthcare utilizations in multiple sclerosis in Taiwan
    Chia-Yun Hsu, Long-Sun Ro, Li-Ju Chen, Chun-Wei Chang, Kuo-Hsuan Chang, I-Hsuan Wu, Amy Lin, Fei-Yuan Hsiao
    Scientific Reports.2021;[Epub]     CrossRef
  • Burden of multiple sclerosis in Iran from 1990 to 2017
    Nima Fattahi, Sahar Saeedi Moghaddam, Farnam Mohebi, Negar Rezaei, Masoud Masinaei, Sahar Mohammadi Fateh, Elham Soleymani Hassanlouei, Farhad Manoochehri, Eghbal Fattahi, Mohammad Ali Sahraian, Maziar Moradi-lakeh, Ali H. Mokdad, Mohsen Naghavi, Farshad
    BMC Neurology.2021;[Epub]     CrossRef
  • Optic neuritis in German children: clinical findings and association with multiple sclerosis
    Felix Tonagel, Helmut Wilhelm, Carina Kelbsch
    Graefe's Archive for Clinical and Experimental Ophthalmology.2020; 258(7): 1523.     CrossRef
  • Evidence of an increased prevalence of multiple sclerosis: a population-based study of Tehran registry during 1999–2018
    Amir Almasi-Hashiani, Mohammad Ali Sahraian, Sharareh Eskandarieh
    BMC Neurology.2020;[Epub]     CrossRef
  • Epstein-Barr virus infection as a predisposing factor for multiple sclerosis. An update from molecular biology, immunology and epidemiology
    David López-Valencia, Ángela Medina-Ortega, Diego Fernando Hoyos-Samboní, Jhan Sebastián Saavedra-Torres, Carolina Salguero
    Revista de la Facultad de Medicina.2019; 67(3): 305.     CrossRef
  • Osteopontin (OPN) as a CSF and blood biomarker for multiple sclerosis: A systematic review and meta-analysis
    Elmira Agah, Arshia Zardoui, Amene Saghazadeh, Mona Ahmadi, Abbas Tafakhori, Nima Rezaei, Heinz Wiendl
    PLOS ONE.2018; 13(1): e0190252.     CrossRef
  • Using inpatient data to estimate the prevalence of Wegener's granulomatosis in China
    Xiao Liu, Yazhou Cui, Yan Li, Chao Wang, Heng Zhao, Jinxiang Han
    Intractable & Rare Diseases Research.2016; 5(1): 31.     CrossRef
  • Estimating epidemiological data of Multiple sclerosis using hospitalized data in Shandong Province, China
    Xiao Liu, Yazhou Cui, Jinxiang Han
    Orphanet Journal of Rare Diseases.2016;[Epub]     CrossRef
  • Epidemiology of Multiple Sclerosis
    Jonathan Howard, Stephen Trevick, David S. Younger
    Neurologic Clinics.2016; 34(4): 919.     CrossRef
  • Quantifying Burden of Disease to Measure Population Health in Korea
    Jihyun Yoon, Seok-Jun Yoon
    Journal of Korean Medical Science.2016; 31(Suppl 2): S101.     CrossRef
  • Modeling the Burden of Abdominal Aortic Aneurysm in the USA in 2013
    Mark Stuntz
    Cardiology.2016; 135(2): 127.     CrossRef
  • Optic Neuritis in Korean Children: Low Risk of Subsequent Multiple Sclerosis
    Young Mi Kim, Hye Young Kim, Min Jeong Cho, Min Jung Kwak, Kyung Hee Park, Gyu Min Yeon, Yunjin Lee, Sang Ook Nam
    Pediatric Neurology.2015; 53(3): 221.     CrossRef
  • No association between CCL2 gene polymorphisms and risk of inflammatory demyelinating diseases in a Korean population
    S. Namgoong, J. S. Bae, H. S. Cheong, J.‐H. Kim, J. Y. Kim, L. H. Kim, H. J. Kim, H. D. Shin
    Tissue Antigens.2014; 84(2): 223.     CrossRef

Epidemiol Health : Epidemiology and Health
TOP