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Diana Valencia 1 Article
Cohort profile: congenital Zika virus infection and child neurodevelopmental outcomes in the ZEN cohort study in Colombia
Maritza Gonzalez, Van T. Tong, Helena Rodriguez, Diana Valencia, Jacqueline Acosta, Margaret A. Honein, Martha L. Ospina, The ZEN Study Team
Epidemiol Health. 2020;42:e2020060.   Published online August 31, 2020
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AbstractAbstract PDF
<i>Zika en Embarazadas y Niños</i> (ZEN) is a prospective cohort study designed to identify risk factors and modifiers for Zika virus (ZIKV) infection in pregnant women, partners, and infants, as well as to assess the risk for adverse maternal, fetal, infant, and childhood outcomes of ZIKV and other congenital infections. ZIKV infection during pregnancy may be associated with longterm sequelae. In the ZEN cohort, 1,519 pregnant women and 287 partners were enrolled from 3 departments within Colombia between February 2017 and January 2018, as well as 1,108 infants born to the pregnant women who were followed to 6 months. The data include baseline questionnaires at enrollment; repeated symptoms and study follow-up questionnaires; the results of lab tests to detect ZIKV and other congenital infections; medical record abstractions; infant physical, eye, and hearing exams; and developmental screening tests. Follow-up of 850 mother-child dyads occurred at 9 months, 12 months, and 18 months with developmental screenings, physical exams, and parent questionnaires. The data will be pooled with those from other prospective cohort studies for an individual participant data meta-analysis of ZIKV infection during pregnancy to characterize pregnancy outcomes and sequelae in children.


Citations to this article as recorded by  
  • Neurodevelopmental assessment of normocephalic children born to Zika virus exposed and unexposed pregnant people
    Jackeline Alger, María Luisa Cafferata, Raquel López, Lisa D. Wiggins, Allison Callejas, Mario Castillo, Jenny Fúnes, Fátima Rico, Diana Valencia, Douglas Varela, Zulma Alvarez, Mabel Berrueta, Harry Bock, Carolina Bustillo, Alejandra Calderón, Alvaro Cig
    Pediatric Research.2024; 95(2): 566.     CrossRef
  • Zika virus prevention behaviors and knowledge among male partners of pregnant people and lack of condom use as a prevention behavior from the Zika en Embarazadas y Niños (ZEN) prospective cohort study, Colombia
    Christina L. Sancken, Ayzsa Tannis, Sandra A. Amouzou, Veronica Burkel, Jeffrey M. Carlson, Suzanne Newton, Suzanne M. Gilboa, Maritza Gonzalez, Diana Valencia, Van T. Tong, Martha Ospina
    BMC Research Notes.2024;[Epub]     CrossRef
  • Zika virus knowledge, attitudes and prevention behaviors among pregnant women in the ZEN cohort study, Colombia, 2017–2018
    Veronica K Burkel, Suzanne M Newton, Jacqueline Acosta, Diana Valencia, Monica Benavides, Van T Tong, Marcela Daza, Christina Sancken, Maritza Gonzalez, Kara Polen, Helena Rodriguez, Milena Borbón, Carol Y Rao, Suzanne M Gilboa, Margaret A Honein, Marta L
    Transactions of The Royal Society of Tropical Medicine and Hygiene.2023; 117(7): 496.     CrossRef
  • Epidemiology of cytomegalovirus Infection among mothers and infants in Colombia
    Angelica Rico, Sheila C. Dollard, Diana Valencia, Sheryll Corchuelo, Van T. Tong, Katherine Laiton‐Donato, Minal M. Amin, Monica Benavides, Phili Wong, Suzanne Newton, Marcela Daza, Jordan Cates, Maritza Gonzalez, Laura D. Zambrano, Marcela M. Mercado, El
    Journal of Medical Virology.2021; 93(11): 6393.     CrossRef
  • Causes of Phenotypic Variability and Disabilities after Prenatal Viral Infections
    Youssef A. Kousa, Reafa A. Hossain
    Tropical Medicine and Infectious Disease.2021; 6(2): 95.     CrossRef

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